IL95012A - דימרים של פפטידים, המווסתים היווצרות דם והפעילים נגד מחלות, הכנתם ותכשירי רוקחות המכילים אותם - Google Patents
דימרים של פפטידים, המווסתים היווצרות דם והפעילים נגד מחלות, הכנתם ותכשירי רוקחות המכילים אותםInfo
- Publication number
- IL95012A IL95012A IL9501290A IL9501290A IL95012A IL 95012 A IL95012 A IL 95012A IL 9501290 A IL9501290 A IL 9501290A IL 9501290 A IL9501290 A IL 9501290A IL 95012 A IL95012 A IL 95012A
- Authority
- IL
- Israel
- Prior art keywords
- lys
- glu
- asp
- acid
- compound
- Prior art date
Links
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- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- BEOOHQFXGBMRKU-UHFFFAOYSA-N sodium cyanoborohydride Chemical compound [Na+].[B-]C#N BEOOHQFXGBMRKU-UHFFFAOYSA-N 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000003595 spectral effect Effects 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 210000000130 stem cell Anatomy 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 210000002536 stromal cell Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- DYHSDKLCOJIUFX-UHFFFAOYSA-N tert-butoxycarbonyl anhydride Chemical compound CC(C)(C)OC(=O)OC(=O)OC(C)(C)C DYHSDKLCOJIUFX-UHFFFAOYSA-N 0.000 description 1
- 150000003512 tertiary amines Chemical class 0.000 description 1
- WROMPOXWARCANT-UHFFFAOYSA-N tfa trifluoroacetic acid Chemical compound OC(=O)C(F)(F)F.OC(=O)C(F)(F)F WROMPOXWARCANT-UHFFFAOYSA-N 0.000 description 1
- 125000004001 thioalkyl group Chemical group 0.000 description 1
- 125000005270 trialkylamine group Chemical group 0.000 description 1
- 210000001215 vagina Anatomy 0.000 description 1
- ABDKAPXRBAPSQN-UHFFFAOYSA-N veratrole Chemical compound COC1=CC=CC=C1OC ABDKAPXRBAPSQN-UHFFFAOYSA-N 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- C07K7/067—Hemoregulatory peptides based on sequence Glp-Glu-Asp-Cys-Lys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Virology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38057889A | 1989-07-14 | 1989-07-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL95012A0 IL95012A0 (en) | 1991-06-10 |
| IL95012A true IL95012A (he) | 1995-03-15 |
Family
ID=23501712
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9501290A IL95012A (he) | 1989-07-14 | 1990-07-09 | דימרים של פפטידים, המווסתים היווצרות דם והפעילים נגד מחלות, הכנתם ותכשירי רוקחות המכילים אותם |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP0408371B1 (he) |
| JP (1) | JP2638666B2 (he) |
| KR (1) | KR910002899A (he) |
| CN (1) | CN1034663C (he) |
| AT (1) | ATE112289T1 (he) |
| AU (1) | AU638468B2 (he) |
| CA (1) | CA2020838C (he) |
| DE (1) | DE69012901T2 (he) |
| DK (1) | DK0408371T3 (he) |
| ES (1) | ES2064642T3 (he) |
| FI (1) | FI94354C (he) |
| HK (1) | HK1004554A1 (he) |
| HU (1) | HU206889B (he) |
| IE (1) | IE65533B1 (he) |
| IL (1) | IL95012A (he) |
| MA (1) | MA21902A1 (he) |
| MX (1) | MX21581A (he) |
| MY (1) | MY106352A (he) |
| NO (1) | NO177713C (he) |
| NZ (1) | NZ234501A (he) |
| PH (1) | PH30055A (he) |
| PL (2) | PL166004B1 (he) |
| PT (1) | PT94702B (he) |
| ZA (1) | ZA905505B (he) |
| ZW (1) | ZW11290A1 (he) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW222280B (he) * | 1991-11-26 | 1994-04-11 | Smithkline Beecham Corp | |
| IL104323A0 (en) * | 1992-01-10 | 1993-05-13 | Smithkline Beecham Corp | Hemoregulatory peptides |
| GB9211677D0 (en) * | 1992-06-02 | 1992-07-15 | Nycomed Bioreg As | Peptide compounds |
| GB9211668D0 (en) | 1992-06-02 | 1992-07-15 | Nycomed Bioreg As | Peptide compounds |
| LV10288B (en) * | 1992-06-02 | 1995-04-20 | Hafslund Nycomed As | Peptide compounds |
| GB9211674D0 (en) | 1992-06-02 | 1992-07-15 | Nycomed Bioreg As | Peptide compounds |
| ES2052447B1 (es) * | 1992-12-14 | 1995-01-16 | Smithkline Beecham Corp | Peptidos hemorreguladores. |
| AU6834194A (en) * | 1993-05-14 | 1994-12-12 | Mallinckrodt Medical, Inc. | Ligand precursors for incorporation into peptides |
| PT713495E (pt) * | 1993-06-08 | 2004-03-31 | Smithkline Beecham Corp | Metodos de aumento da bioactividade de quimocinas |
| GB9314200D0 (en) * | 1993-07-09 | 1993-08-18 | Hafslund Nycomed As | Peptide compounds |
| JPH09504301A (ja) * | 1993-10-29 | 1997-04-28 | スミスクライン・ビーチャム・コーポレイション | 血液調節ペプチド |
| GB9324691D0 (en) * | 1993-12-01 | 1994-01-19 | Hafslund Nycomed As | Peptide compounds |
| US5714469A (en) * | 1994-09-01 | 1998-02-03 | Smithkline Beecham Corporation | Method of treating sepsis |
| CN1212706A (zh) * | 1996-02-13 | 1999-03-31 | 阿克佐诺贝尔公司 | 丝氨酸蛋白酶抑制剂 |
| TW442452B (en) * | 1996-03-01 | 2001-06-23 | Akzo Nobel Nv | Serine protease inhibitors having an alkynylamino side chain |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2860734D1 (en) * | 1977-06-08 | 1981-09-03 | Merck & Co Inc | Somatostatin analogs, process for their preparation and pharmaceutical compositions containing them |
| GB8626539D0 (en) * | 1986-11-06 | 1986-12-10 | Nycomed As | Peptide compounds |
-
1990
- 1990-07-06 ZW ZW112/90A patent/ZW11290A1/xx unknown
- 1990-07-09 IL IL9501290A patent/IL95012A/he not_active IP Right Cessation
- 1990-07-10 PH PH40815A patent/PH30055A/en unknown
- 1990-07-10 CA CA002020838A patent/CA2020838C/en not_active Expired - Fee Related
- 1990-07-12 ES ES90307657T patent/ES2064642T3/es not_active Expired - Lifetime
- 1990-07-12 AT AT90307657T patent/ATE112289T1/de not_active IP Right Cessation
- 1990-07-12 EP EP90307657A patent/EP0408371B1/en not_active Expired - Lifetime
- 1990-07-12 DE DE69012901T patent/DE69012901T2/de not_active Expired - Fee Related
- 1990-07-12 DK DK90307657.8T patent/DK0408371T3/da active
- 1990-07-12 PL PL90301975A patent/PL166004B1/pl unknown
- 1990-07-12 PL PL90286043A patent/PL165133B1/pl unknown
- 1990-07-12 IE IE254790A patent/IE65533B1/en not_active IP Right Cessation
- 1990-07-13 MY MYPI90001180A patent/MY106352A/en unknown
- 1990-07-13 FI FI903571A patent/FI94354C/fi not_active IP Right Cessation
- 1990-07-13 JP JP2187011A patent/JP2638666B2/ja not_active Expired - Lifetime
- 1990-07-13 AU AU59014/90A patent/AU638468B2/en not_active Ceased
- 1990-07-13 CN CN90107067A patent/CN1034663C/zh not_active Expired - Fee Related
- 1990-07-13 HU HU904201A patent/HU206889B/hu not_active IP Right Cessation
- 1990-07-13 MA MA22171A patent/MA21902A1/fr unknown
- 1990-07-13 NZ NZ234501A patent/NZ234501A/xx unknown
- 1990-07-13 ZA ZA905505A patent/ZA905505B/xx unknown
- 1990-07-13 KR KR1019900010824A patent/KR910002899A/ko not_active Ceased
- 1990-07-13 MX MX2158190A patent/MX21581A/es unknown
- 1990-07-13 PT PT94702A patent/PT94702B/pt unknown
- 1990-07-13 NO NO903148A patent/NO177713C/no not_active IP Right Cessation
-
1998
- 1998-04-28 HK HK98103619A patent/HK1004554A1/en not_active IP Right Cessation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |