IL91046A - Pharmaceutical and diagnostic compositions containing metal complexes of poly(carboxymethyl)-poly [azabicyclo (x,3,1) alkane] derivatives some new such derivatives and their preparation - Google Patents

Pharmaceutical and diagnostic compositions containing metal complexes of poly(carboxymethyl)-poly [azabicyclo (x,3,1) alkane] derivatives some new such derivatives and their preparation

Info

Publication number
IL91046A
IL91046A IL9104689A IL9104689A IL91046A IL 91046 A IL91046 A IL 91046A IL 9104689 A IL9104689 A IL 9104689A IL 9104689 A IL9104689 A IL 9104689A IL 91046 A IL91046 A IL 91046A
Authority
IL
Israel
Prior art keywords
group
atom
radical
optionally
mmol
Prior art date
Application number
IL9104689A
Other languages
English (en)
Other versions
IL91046A0 (en
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL91046A0 publication Critical patent/IL91046A0/xx
Publication of IL91046A publication Critical patent/IL91046A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
    • C07D255/04—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
IL9104689A 1988-07-20 1989-07-19 Pharmaceutical and diagnostic compositions containing metal complexes of poly(carboxymethyl)-poly [azabicyclo (x,3,1) alkane] derivatives some new such derivatives and their preparation IL91046A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3825040A DE3825040A1 (de) 1988-07-20 1988-07-20 5- oder 6-ring- enthaltende makrocyclische polyaza-verbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel

Publications (2)

Publication Number Publication Date
IL91046A0 IL91046A0 (en) 1990-02-09
IL91046A true IL91046A (en) 1995-10-31

Family

ID=6359368

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9104689A IL91046A (en) 1988-07-20 1989-07-19 Pharmaceutical and diagnostic compositions containing metal complexes of poly(carboxymethyl)-poly [azabicyclo (x,3,1) alkane] derivatives some new such derivatives and their preparation

Country Status (15)

Country Link
EP (1) EP0352218B1 (no)
JP (1) JP2877844B2 (no)
AT (1) ATE118775T1 (no)
CA (1) CA1341035C (no)
DE (2) DE3825040A1 (no)
DK (1) DK171097B1 (no)
ES (1) ES2068908T3 (no)
FI (1) FI893509A (no)
GR (1) GR3015162T3 (no)
IE (1) IE66693B1 (no)
IL (1) IL91046A (no)
NO (1) NO179104C (no)
NZ (1) NZ229996A (no)
PT (1) PT91211B (no)
ZA (1) ZA895543B (no)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4001655A1 (de) * 1990-01-18 1991-07-25 Schering Ag 6-ring enthaltende makrocyclische tetraaza-verbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
US5334371A (en) * 1988-07-20 1994-08-02 Schering Aktiengesellschaft Marcocyclic polyaza bicyclo compounds containing 5 or 6 membered rings, and method for MRI
DE69026499T2 (de) * 1989-01-17 1996-09-19 Xyrofin Oy Verfahren zur herstellung von xylitol aus xylose enthaltenden gemischen
FR2652589B1 (fr) * 1989-10-04 1995-02-17 Roquette Freres Procede de fabrication de xylitol et de produits riches en xylitol.
WO1991010669A1 (en) * 1990-01-19 1991-07-25 Cockbain, Julian, Roderick, Michaelson Chelating compounds
GB9001245D0 (en) * 1990-01-19 1990-03-21 Salutar Inc Compounds
US5330737A (en) * 1991-12-06 1994-07-19 Mallinckrodt Medical, Inc. Nitrogen-sulfur ligands as opiate receptor drug mimics
ZA929576B (en) * 1991-12-10 1994-06-10 Dow Chemical Co Bicyclopolyazamacrocyclophosphonic acids their complexes and conjugates for use as contrast agents and processes for their preparation
US5739294A (en) * 1991-12-10 1998-04-14 The Dow Chemical Company Bicyclopol yazamacrocyclophosphonic acid complexes for use as contrast agents
US5428139A (en) * 1991-12-10 1995-06-27 The Dow Chemical Company Bicyclopolyazamacrocyclophosphonic acid complexes for use as radiopharmaceuticals
CA2103553A1 (en) * 1991-12-10 1993-06-11 Garry E. Kiefer Bicyclopolyazamacrocyclocarboxylic acid complexes their conjugates, processes for their preparation, and use as radiopharmaceuticals
WO1994026313A1 (en) * 1993-05-06 1994-11-24 The Dow Chemical Company Bicyclopolyazamacrocyclocarboxylic acid complexes, their conjugates, processes for their preparation, and use as contrast agents
WO1993011800A1 (en) * 1991-12-10 1993-06-24 The Dow Chemical Company Bicycle-polyazamacrocyclocarboxylic acid complexes, conjugates, preparation and use as contrast agents
US5480990A (en) * 1991-12-10 1996-01-02 The Dow Chemical Company Bicyclopolyazamacrocyclocarboxylic acid complexes for use as contrast agents
US5385893A (en) * 1993-05-06 1995-01-31 The Dow Chemical Company Tricyclopolyazamacrocyclophosphonic acids, complexes and derivatives thereof, for use as contrast agents
AU4237493A (en) * 1993-05-06 1994-12-12 Dow Chemical Company, The Bicyclopolyazamacrocyclocarboxylic acid complexes, their conjugates, processes for their preparation, and use as radiopharmaceuticals
US5480970A (en) * 1993-12-22 1996-01-02 Resolution Pharmaceuticals Metal chelators
US5569745A (en) * 1994-02-25 1996-10-29 Resolution Pharmaceuticals Inc. Peptide-Chelator conjugates
ATE254129T1 (de) * 1996-04-19 2003-11-15 Dow Global Technologies Inc Fluoreszierende chelate als gewebespezifische bildgebende mittel
FR2794744B1 (fr) * 1999-06-09 2001-09-21 Guerbet Sa Complexes metalliques de polyaminoacides bicycliques, leur procede de preparation et leur application en imagerie medicale
WO2002026267A2 (en) * 2000-09-25 2002-04-04 The Procter & Gamble Company Manganes complexes for magnetic resonance imaging
FR2891830B1 (fr) * 2005-10-07 2011-06-24 Guerbet Sa Composes a chaines aminoalcools courtes et complexes metalliques pour l'imagerie medicale
US8926945B2 (en) 2005-10-07 2015-01-06 Guerbet Compounds comprising a biological target recognizing part, coupled to a signal part capable of complexing gallium
US8986650B2 (en) 2005-10-07 2015-03-24 Guerbet Complex folate-NOTA-Ga68
GB201610738D0 (en) 2016-06-20 2016-08-03 Ge Healthcare As Chelate compounds
US11110186B2 (en) * 2017-12-20 2021-09-07 General Electric Company Anionic chelate compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2478456A (en) 1946-03-15 1949-08-09 Socony Vaeuum Oil Company Inc Solvent dewaxing
US3194818A (en) 1963-08-14 1965-07-13 Sterling Drug Inc Alpha-aryl or aralkyl furfurylamines
DE3129906C3 (de) * 1981-07-24 1996-12-19 Schering Ag Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik
DE3150917A1 (de) 1981-12-18 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen "2-amino-1-(1,3-dioxolan-4-yl)-ethanol-verbindungen, deren herstellung und verwendung zur weiterverarbeitung"
NL194579C (nl) * 1983-01-21 2002-08-05 Schering Ag Diagnostisch middel.
DE3324235A1 (de) * 1983-07-01 1985-01-10 Schering AG, 1000 Berlin und 4709 Bergkamen Neue komplexbildner, komplexe und komplexsalze
SE8502573D0 (sv) * 1985-05-23 1985-05-23 Jouko Kanakre Fluorescent lanthanide chelates useful as labels of physiologically active materials
DE3772785D1 (de) 1986-01-23 1991-10-17 Squibb & Sons Inc 1-substituiertes-4,7,10-triscarboxymethyl-1,4,7,10-tetraazacyclododecan und analoga.

Also Published As

Publication number Publication date
AU3827589A (en) 1990-02-01
DE58909022D1 (de) 1995-04-06
EP0352218A3 (de) 1991-01-16
PT91211B (pt) 1995-03-01
ATE118775T1 (de) 1995-03-15
NZ229996A (en) 1992-05-26
CA1341035C (en) 2000-06-20
JP2877844B2 (ja) 1999-04-05
GR3015162T3 (en) 1995-05-31
DK358889D0 (da) 1989-07-19
DK171097B1 (da) 1996-06-03
EP0352218A2 (de) 1990-01-24
PT91211A (pt) 1990-02-08
EP0352218B1 (de) 1995-02-22
NO179104B (no) 1996-04-29
DE3825040A1 (de) 1990-01-25
IL91046A0 (en) 1990-02-09
AU637052B2 (en) 1993-05-20
FI893509A (fi) 1990-01-21
JPH02104588A (ja) 1990-04-17
ES2068908T3 (es) 1995-05-01
NO179104C (no) 1996-08-07
DK358889A (da) 1990-01-21
NO892959D0 (no) 1989-07-19
IE892335L (en) 1990-01-20
IE66693B1 (en) 1996-01-24
FI893509A0 (fi) 1989-07-20
ZA895543B (en) 1990-05-30
NO892959L (no) 1990-01-22

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Legal Events

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KB Patent renewed
KB Patent renewed
RH1 Patent not in force