FI893509A0 - Makrocykliska polyazafoereningar, vilka innehaoller en 5- eller 6-ring, foerfaranden foer framstaellning daerav och dessa innehaollande farmaceutiska medel. - Google Patents

Makrocykliska polyazafoereningar, vilka innehaoller en 5- eller 6-ring, foerfaranden foer framstaellning daerav och dessa innehaollande farmaceutiska medel.

Info

Publication number
FI893509A0
FI893509A0 FI893509A FI893509A FI893509A0 FI 893509 A0 FI893509 A0 FI 893509A0 FI 893509 A FI893509 A FI 893509A FI 893509 A FI893509 A FI 893509A FI 893509 A0 FI893509 A0 FI 893509A0
Authority
FI
Finland
Prior art keywords
group
radical
atom
image
hydrogen
Prior art date
Application number
FI893509A
Other languages
English (en)
Other versions
FI893509A (fi
Inventor
Johannes Platzek
Bernd Raduechel
Heinz Gries
Hans-Joachim Weinmann
Ulrich Speck
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of FI893509A0 publication Critical patent/FI893509A0/fi
Publication of FI893509A publication Critical patent/FI893509A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
    • C07D255/04—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
FI893509A 1988-07-20 1989-07-20 Makrocykliska polyazafoereningar, vilka innehaoller en 5- eller 6-ring, foerfaranden foer framstaellning daerav och dessa innehaollande farmaceutiska medel. FI893509A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3825040A DE3825040A1 (de) 1988-07-20 1988-07-20 5- oder 6-ring- enthaltende makrocyclische polyaza-verbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel

Publications (2)

Publication Number Publication Date
FI893509A0 true FI893509A0 (fi) 1989-07-20
FI893509A FI893509A (fi) 1990-01-21

Family

ID=6359368

Family Applications (1)

Application Number Title Priority Date Filing Date
FI893509A FI893509A (fi) 1988-07-20 1989-07-20 Makrocykliska polyazafoereningar, vilka innehaoller en 5- eller 6-ring, foerfaranden foer framstaellning daerav och dessa innehaollande farmaceutiska medel.

Country Status (15)

Country Link
EP (1) EP0352218B1 (fi)
JP (1) JP2877844B2 (fi)
AT (1) ATE118775T1 (fi)
CA (1) CA1341035C (fi)
DE (2) DE3825040A1 (fi)
DK (1) DK171097B1 (fi)
ES (1) ES2068908T3 (fi)
FI (1) FI893509A (fi)
GR (1) GR3015162T3 (fi)
IE (1) IE66693B1 (fi)
IL (1) IL91046A (fi)
NO (1) NO179104C (fi)
NZ (1) NZ229996A (fi)
PT (1) PT91211B (fi)
ZA (1) ZA895543B (fi)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4001655A1 (de) * 1990-01-18 1991-07-25 Schering Ag 6-ring enthaltende makrocyclische tetraaza-verbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
US5334371A (en) * 1988-07-20 1994-08-02 Schering Aktiengesellschaft Marcocyclic polyaza bicyclo compounds containing 5 or 6 membered rings, and method for MRI
JP2947609B2 (ja) * 1989-01-17 1999-09-13 スオメン ザイロフィン オサケ イティオ キシロース含有混合物からのキシリトールの製造方法
FR2652589B1 (fr) * 1989-10-04 1995-02-17 Roquette Freres Procede de fabrication de xylitol et de produits riches en xylitol.
GB9001245D0 (en) * 1990-01-19 1990-03-21 Salutar Inc Compounds
CA2072080A1 (en) * 1990-01-19 1991-07-20 Jo Klaveness Chelating compounds
US5330737A (en) * 1991-12-06 1994-07-19 Mallinckrodt Medical, Inc. Nitrogen-sulfur ligands as opiate receptor drug mimics
US5739294A (en) * 1991-12-10 1998-04-14 The Dow Chemical Company Bicyclopol yazamacrocyclophosphonic acid complexes for use as contrast agents
US5480990A (en) * 1991-12-10 1996-01-02 The Dow Chemical Company Bicyclopolyazamacrocyclocarboxylic acid complexes for use as contrast agents
WO1994026313A1 (en) * 1993-05-06 1994-11-24 The Dow Chemical Company Bicyclopolyazamacrocyclocarboxylic acid complexes, their conjugates, processes for their preparation, and use as contrast agents
WO1993012112A1 (en) * 1991-12-10 1993-06-24 The Dow Chemical Company Bicyclopolyazamacrocyclocarboxylic acid complexes, their conjugates processes for their preparation, and use as radiopharmaceuticals
ATE192047T1 (de) * 1991-12-10 2000-05-15 Dow Chemical Co Bicylclische, polyazamakrocyclocarbonsäure- komplexe, konjugate, herstellung und verwendung als kontraststoffe
MX9207166A (es) * 1991-12-10 1993-07-01 Dow Chemical Co Acidos biciclopoliazamacrociclofosfonicos, sus complejos y conjugados, para uso como agentes de contraste, y procedimientos para su preparacion.
US5428139A (en) * 1991-12-10 1995-06-27 The Dow Chemical Company Bicyclopolyazamacrocyclophosphonic acid complexes for use as radiopharmaceuticals
AU4237493A (en) * 1993-05-06 1994-12-12 Dow Chemical Company, The Bicyclopolyazamacrocyclocarboxylic acid complexes, their conjugates, processes for their preparation, and use as radiopharmaceuticals
US5385893A (en) * 1993-05-06 1995-01-31 The Dow Chemical Company Tricyclopolyazamacrocyclophosphonic acids, complexes and derivatives thereof, for use as contrast agents
US5480970A (en) * 1993-12-22 1996-01-02 Resolution Pharmaceuticals Metal chelators
US5569745A (en) * 1994-02-25 1996-10-29 Resolution Pharmaceuticals Inc. Peptide-Chelator conjugates
IL126659A (en) * 1996-04-19 2003-05-29 Dow Global Technologies Inc Fluorescent chelates as visual tissue specific imaging agents
FR2794744B1 (fr) * 1999-06-09 2001-09-21 Guerbet Sa Complexes metalliques de polyaminoacides bicycliques, leur procede de preparation et leur application en imagerie medicale
EP1322340A2 (en) * 2000-09-25 2003-07-02 The Procter & Gamble Company Manganese complexes for magnetic resonance imaging
EP1940841B9 (fr) * 2005-10-07 2017-04-19 Guerbet Composes comprenant une partie de reconnaissance d'une cible biologique, couplee a une partie de signal capable de complexer le gallium
FR2891830B1 (fr) * 2005-10-07 2011-06-24 Guerbet Sa Composes a chaines aminoalcools courtes et complexes metalliques pour l'imagerie medicale
US8986650B2 (en) 2005-10-07 2015-03-24 Guerbet Complex folate-NOTA-Ga68
GB201610738D0 (en) 2016-06-20 2016-08-03 Ge Healthcare As Chelate compounds
JP7332600B2 (ja) * 2017-12-20 2023-08-23 ゼネラル・エレクトリック・カンパニイ アニオン性キレート化合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2478456A (en) 1946-03-15 1949-08-09 Socony Vaeuum Oil Company Inc Solvent dewaxing
US3194818A (en) 1963-08-14 1965-07-13 Sterling Drug Inc Alpha-aryl or aralkyl furfurylamines
DE3129906C3 (de) * 1981-07-24 1996-12-19 Schering Ag Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik
DE3150917A1 (de) 1981-12-18 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen "2-amino-1-(1,3-dioxolan-4-yl)-ethanol-verbindungen, deren herstellung und verwendung zur weiterverarbeitung"
NL194579C (nl) * 1983-01-21 2002-08-05 Schering Ag Diagnostisch middel.
DE3324235A1 (de) * 1983-07-01 1985-01-10 Schering AG, 1000 Berlin und 4709 Bergkamen Neue komplexbildner, komplexe und komplexsalze
SE8502573D0 (sv) * 1985-05-23 1985-05-23 Jouko Kanakre Fluorescent lanthanide chelates useful as labels of physiologically active materials
DE3772785D1 (de) 1986-01-23 1991-10-17 Squibb & Sons Inc 1-substituiertes-4,7,10-triscarboxymethyl-1,4,7,10-tetraazacyclododecan und analoga.

Also Published As

Publication number Publication date
IE892335L (en) 1990-01-20
CA1341035C (en) 2000-06-20
JP2877844B2 (ja) 1999-04-05
NO179104C (no) 1996-08-07
DE58909022D1 (de) 1995-04-06
NO892959D0 (no) 1989-07-19
AU637052B2 (en) 1993-05-20
IL91046A (en) 1995-10-31
IE66693B1 (en) 1996-01-24
DK171097B1 (da) 1996-06-03
AU3827589A (en) 1990-02-01
NZ229996A (en) 1992-05-26
NO179104B (no) 1996-04-29
PT91211A (pt) 1990-02-08
ATE118775T1 (de) 1995-03-15
NO892959L (no) 1990-01-22
DE3825040A1 (de) 1990-01-25
PT91211B (pt) 1995-03-01
EP0352218B1 (de) 1995-02-22
GR3015162T3 (en) 1995-05-31
DK358889D0 (da) 1989-07-19
EP0352218A2 (de) 1990-01-24
IL91046A0 (en) 1990-02-09
EP0352218A3 (de) 1991-01-16
JPH02104588A (ja) 1990-04-17
ES2068908T3 (es) 1995-05-01
FI893509A (fi) 1990-01-21
DK358889A (da) 1990-01-21
ZA895543B (en) 1990-05-30

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Legal Events

Date Code Title Description
FD Application lapsed
FD Application lapsed

Owner name: SCHERING AKTIENGESELLSCHAFT