IL90533A - History of 5-phenyl-8-nitro-2,3,4,5-tetrahydro-H1- 3-benzazepine, their preparation and pharmaceutical preparations containing them - Google Patents
History of 5-phenyl-8-nitro-2,3,4,5-tetrahydro-H1- 3-benzazepine, their preparation and pharmaceutical preparations containing themInfo
- Publication number
- IL90533A IL90533A IL9053389A IL9053389A IL90533A IL 90533 A IL90533 A IL 90533A IL 9053389 A IL9053389 A IL 9053389A IL 9053389 A IL9053389 A IL 9053389A IL 90533 A IL90533 A IL 90533A
- Authority
- IL
- Israel
- Prior art keywords
- bridge
- benzazepines
- hydroxy
- hydrogen
- benzazepine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK325188A DK325188D0 (da) | 1988-06-15 | 1988-06-15 | Hidtil ukendte benzazepinderivater |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL90533A0 IL90533A0 (en) | 1990-01-18 |
| IL90533A true IL90533A (en) | 1994-05-30 |
Family
ID=8120790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9053389A IL90533A (en) | 1988-06-15 | 1989-06-05 | History of 5-phenyl-8-nitro-2,3,4,5-tetrahydro-H1- 3-benzazepine, their preparation and pharmaceutical preparations containing them |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US5010074A (de) |
| EP (1) | EP0347672B1 (de) |
| JP (1) | JP2769718B2 (de) |
| AT (1) | ATE102188T1 (de) |
| AU (1) | AU622911B2 (de) |
| CA (1) | CA1317938C (de) |
| DE (1) | DE68913367T2 (de) |
| DK (1) | DK325188D0 (de) |
| ES (1) | ES2061794T3 (de) |
| FI (1) | FI93354C (de) |
| IE (1) | IE891932L (de) |
| IL (1) | IL90533A (de) |
| NO (1) | NO173865C (de) |
| NZ (1) | NZ229521A (de) |
| PT (1) | PT90883B (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK67489D0 (da) * | 1989-02-14 | 1989-02-14 | Novo Industri As | Nye benzazepinderivater |
| US5158948A (en) * | 1990-11-16 | 1992-10-27 | Abbott Laboratories | Tetracyclic spirobenzazepine dopamine antagonists |
| DK23392D0 (da) * | 1992-02-24 | 1992-02-24 | Novo Nordisk As | Heterocykliske forbindelser, deres anvendelse og fremstilling |
| US5470850A (en) * | 1992-02-24 | 1995-11-28 | Novo Nordisk A/S | 2,3,4,5-tetrahydro-1H-3-benzazepines |
| IL131670A (en) * | 1997-03-12 | 2005-07-25 | Addex Pharmaceuticals Sa | Use of 2,3,4,5-tetrahydro-1h-3-benzazepines for the manufacture of a pharmaceutical composition for the treatment of sleep disorders |
| US6277844B1 (en) | 1998-09-14 | 2001-08-21 | Sydney Spector | Compound for selective treatment of malignant cells by inhibiting cell cycle progression, decreasing Bcl2, and increasing apoptosis |
| GB0130576D0 (en) * | 2001-12-20 | 2002-02-06 | Cenes Ltd | Dopamine D1 receptor agonist pro-drug compounds & derivatives |
| US7211574B2 (en) * | 2002-08-29 | 2007-05-01 | Schering Corporation | Selective D1/D5 receptor antagonists for the treatment of obesity and CNS disorders |
| MXPA05006567A (es) | 2002-12-20 | 2005-08-16 | Glaxo Group Ltd | Derivados de benzazepina para el tratamiento de trastornos neurologicos. |
| WO2005035504A2 (en) * | 2003-05-22 | 2005-04-21 | Schering Corporation | 5-h -benzo [d] naphth [2, 1-b] azepine derivative as selective d1/d5 receptor antagonists for the treatment of obesity and cns disorders |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA974989A (en) * | 1968-03-11 | 1975-09-23 | Wallace And Tiernan Inc. | Process for preparing 1,2,4,5-tetrahydro-3h,3-benzazepines and products obtained thereby |
| US4210749A (en) * | 1974-11-12 | 1980-07-01 | Pennwalt Corporation | Substituted 1,2,4,5-tetrahydro-3H,3 benzazepines |
| ZA792043B (en) * | 1978-05-08 | 1980-05-28 | Scherico Ltd | Esters of substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines,process for the preparation thereof and pharmaceutical compositions containing them |
| US4284556A (en) * | 1980-01-31 | 1981-08-18 | Smithkline Corporation | 7,8-Amino, hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines |
| US4327023A (en) * | 1980-01-31 | 1982-04-27 | Smithkline Corporation | Intermediates for preparing 7,8-amino, hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines |
| DK180485D0 (da) * | 1985-04-22 | 1985-04-23 | Novo Industri As | Nitrogenholdige forbindelser |
| WO1987004430A2 (en) * | 1986-01-16 | 1987-07-30 | Schering Corporation | Fused benzazepines |
| EP0244088A3 (de) * | 1986-04-03 | 1989-03-15 | Smithkline Beecham Corporation | 1-Phenyl-3-benzazepin-Verbindungen und diese enthaltende Arzneimittel zur Behandlung von Störungen des gastrointestinalen Bewegungsvermögens |
-
1988
- 1988-06-15 DK DK325188A patent/DK325188D0/da not_active Application Discontinuation
-
1989
- 1989-06-05 IL IL9053389A patent/IL90533A/en unknown
- 1989-06-09 ES ES89110490T patent/ES2061794T3/es not_active Expired - Lifetime
- 1989-06-09 DE DE68913367T patent/DE68913367T2/de not_active Expired - Lifetime
- 1989-06-09 AT AT89110490T patent/ATE102188T1/de not_active IP Right Cessation
- 1989-06-09 EP EP89110490A patent/EP0347672B1/de not_active Expired - Lifetime
- 1989-06-12 US US07/365,250 patent/US5010074A/en not_active Expired - Lifetime
- 1989-06-13 CA CA000602684A patent/CA1317938C/en not_active Expired - Lifetime
- 1989-06-13 NZ NZ229521A patent/NZ229521A/en unknown
- 1989-06-14 NO NO892476A patent/NO173865C/no not_active IP Right Cessation
- 1989-06-14 AU AU36359/89A patent/AU622911B2/en not_active Expired
- 1989-06-15 JP JP1150662A patent/JP2769718B2/ja not_active Expired - Lifetime
- 1989-06-15 FI FI892946A patent/FI93354C/fi active IP Right Grant
- 1989-06-15 IE IE891932A patent/IE891932L/xx not_active IP Right Cessation
- 1989-06-15 PT PT90883A patent/PT90883B/pt not_active IP Right Cessation
-
1990
- 1990-02-07 US US07/477,450 patent/US5025009A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FI93354B (fi) | 1994-12-15 |
| NO173865C (no) | 1994-02-16 |
| IE891932L (en) | 1989-12-15 |
| JPH0240364A (ja) | 1990-02-09 |
| FI892946A0 (fi) | 1989-06-15 |
| NO173865B (no) | 1993-11-08 |
| EP0347672A1 (de) | 1989-12-27 |
| IL90533A0 (en) | 1990-01-18 |
| PT90883B (pt) | 1994-12-30 |
| NO892476L (no) | 1989-12-18 |
| DE68913367D1 (de) | 1994-04-07 |
| DE68913367T2 (de) | 1994-06-01 |
| FI892946A (fi) | 1989-12-16 |
| AU622911B2 (en) | 1992-04-30 |
| PT90883A (pt) | 1989-12-29 |
| CA1317938C (en) | 1993-05-18 |
| ATE102188T1 (de) | 1994-03-15 |
| AU3635989A (en) | 1989-12-21 |
| DK325188D0 (da) | 1988-06-15 |
| NO892476D0 (no) | 1989-06-14 |
| US5025009A (en) | 1991-06-18 |
| EP0347672B1 (de) | 1994-03-02 |
| FI93354C (fi) | 1995-03-27 |
| US5010074A (en) | 1991-04-23 |
| NZ229521A (en) | 1991-12-23 |
| ES2061794T3 (es) | 1994-12-16 |
| JP2769718B2 (ja) | 1998-06-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| HP | Change in proprietorship | ||
| KB | Patent renewed | ||
| HP | Change in proprietorship | ||
| KB | Patent renewed |