IL90231A0 - 1,1-dioxo-cephem-4-carbothiolic acid derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

1,1-dioxo-cephem-4-carbothiolic acid derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL90231A0
IL90231A0 IL90231A IL9023189A IL90231A0 IL 90231 A0 IL90231 A0 IL 90231A0 IL 90231 A IL90231 A IL 90231A IL 9023189 A IL9023189 A IL 9023189A IL 90231 A0 IL90231 A0 IL 90231A0
Authority
IL
Israel
Prior art keywords
cephem
dioxo
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL90231A
Other languages
English (en)
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of IL90231A0 publication Critical patent/IL90231A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Peptides Or Proteins (AREA)
IL90231A 1988-05-13 1989-05-08 1,1-dioxo-cephem-4-carbothiolic acid derivatives,their preparation and pharmaceutical compositions containing them IL90231A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888811388A GB8811388D0 (en) 1988-05-13 1988-05-13 1,1-dioxo-cephem-4-carbothiolic acid derivatives

Publications (1)

Publication Number Publication Date
IL90231A0 true IL90231A0 (en) 1989-12-15

Family

ID=10636869

Family Applications (1)

Application Number Title Priority Date Filing Date
IL90231A IL90231A0 (en) 1988-05-13 1989-05-08 1,1-dioxo-cephem-4-carbothiolic acid derivatives,their preparation and pharmaceutical compositions containing them

Country Status (19)

Country Link
US (1) US5356888A (xx)
EP (1) EP0378604B1 (xx)
JP (1) JPH02504285A (xx)
KR (1) KR0147300B1 (xx)
AU (1) AU628821B2 (xx)
DE (1) DE68913498T2 (xx)
DK (1) DK10190A (xx)
ES (1) ES2016017A6 (xx)
FI (1) FI94642C (xx)
GB (1) GB8811388D0 (xx)
GR (1) GR1002249B (xx)
HU (1) HU208141B (xx)
IE (1) IE66309B1 (xx)
IL (1) IL90231A0 (xx)
NZ (1) NZ229023A (xx)
PT (1) PT90530B (xx)
RU (1) RU2091383C1 (xx)
WO (1) WO1989010926A1 (xx)
ZA (1) ZA893569B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991004977A1 (en) * 1989-10-06 1991-04-18 Synphar Laboratories, Inc. Novel 2-spirocyclopropyl cephalosporin sulfone derivatives and processes for the preparation thereof
US5264429A (en) * 1989-10-06 1993-11-23 Synphar Laboratories, Inc. 2-spirocyclopropyl cephalosporin sulfone derivatives
US5258377A (en) * 1991-04-08 1993-11-02 Taiho Pharmaceutical Co., Ltd. 2-spirocyclopropyl 4-acylcephems
US5446037A (en) * 1991-12-05 1995-08-29 Synphar Laboratories, Inc. 2-[(substituted) methylene]cephalosporin sulfones as antiinflammatory, antidegenerative and antithrombin agents
US5439904A (en) * 1993-12-07 1995-08-08 Synphar Laboratories, Inc. 2-spiro(2'-spirocycloalkyl)cyclopropyl cephalosporin sulfones as antiinflammatory and antigenerative agents
US5629306A (en) 1994-12-09 1997-05-13 Research Corporation Technologies, Inc. 7-alkylidene cephalosporanic acid derivatives and methods of using the same
JPH11511463A (ja) * 1995-08-31 1999-10-05 スミスクライン・ビーチャム・コーポレイション インターロイキン変換酵素およびアポプトーシス
US5760027A (en) * 1996-12-06 1998-06-02 Research Corporation Technologies, Inc. Use of 7-alkylidene cephalosporins to inhibit elastase activity
US6407091B1 (en) * 1999-04-15 2002-06-18 Research Corporation Technologies, Inc. β-lactamase inhibiting compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1187323A (en) * 1967-06-26 1970-04-08 Fujisawa Pharmaceutical Co Sydnone and Sydnone Imine Derivatives of 7-Aminocephalosporanic Acids and Preparation thereof
US4623645A (en) * 1983-04-18 1986-11-18 Merck & Co., Inc. Substituted cephalosporin sulfoxides as anti-inflammatory and antidegenerative agents
US4547371A (en) * 1983-04-18 1985-10-15 Merck & Co., Inc. Substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents
EP0124081A3 (en) * 1983-05-02 1986-11-26 Merck & Co. Inc. New substituted cephalosporin sulfones as antiinflammatory and antidegenerative agents, pharmaceutical compositions containing the same and processes for making them
US4699904A (en) * 1985-07-01 1987-10-13 Merck & Co., Inc. Tetrazolyl derivatives of β-lactams useful as elastase inhibitors
NZ222399A (en) * 1986-11-12 1991-07-26 Merck & Co Inc Cephalosporin derivatives; pharmaceutical compositions and processes for preparation
GB8808701D0 (en) * 1988-04-13 1988-05-18 Erba Carlo Spa Beta-lactam derivatives
US5258377A (en) * 1991-04-08 1993-11-02 Taiho Pharmaceutical Co., Ltd. 2-spirocyclopropyl 4-acylcephems

Also Published As

Publication number Publication date
HU893631D0 (en) 1990-11-28
ZA893569B (en) 1990-01-31
EP0378604B1 (en) 1994-03-02
GR1002249B (en) 1996-04-23
GR890100309A (el) 1990-03-12
HU208141B (en) 1993-08-30
IE891550L (en) 1989-11-13
DE68913498D1 (en) 1994-04-07
RU2091383C1 (ru) 1997-09-27
KR900701800A (ko) 1990-12-04
AU3579289A (en) 1989-11-29
FI900145A0 (fi) 1990-01-11
PT90530A (pt) 1989-11-30
EP0378604A1 (en) 1990-07-25
DE68913498T2 (de) 1994-06-09
DK10190A (da) 1990-01-15
IE66309B1 (en) 1995-12-27
KR0147300B1 (ko) 1998-08-17
DK10190D0 (da) 1990-01-12
JPH02504285A (ja) 1990-12-06
PT90530B (pt) 1994-11-30
FI94642B (fi) 1995-06-30
NZ229023A (en) 1990-09-26
GB8811388D0 (en) 1988-06-15
FI94642C (fi) 1995-10-10
WO1989010926A1 (en) 1989-11-16
ES2016017A6 (es) 1990-10-01
HUT54166A (en) 1991-01-28
AU628821B2 (en) 1992-09-24
US5356888A (en) 1994-10-18
FI900145A (fi) 1990-01-11

Similar Documents

Publication Publication Date Title
IL91129A0 (en) Aminomethyloxooxazolidinyl arylbenzene derivatives,their preparation and pharmaceutical compositions containing them
IL90245A0 (en) Ethenediamine derivatives,their preparation and pharmaceutical compositions containing them
IL93845A0 (en) Amino acid derivatives,their preparation and pharmaceutical compositions containing them
IL85136A0 (en) Peptide derivatives,their preparation and pharmaceutical compositions containing them
IL86798A0 (en) 2,2-dimethylchroman-3-ol derivatives,their preparation and pharmaceutical compositions containing them
IL76405A0 (en) 1,3-diacyl-2-oxyindole derivatives,their preparation and pharmaceutical compositions containing them
IL84944A (en) Pharmaceutical compositions containing 1,2-dihydro-3h-indazolone derivatives,some new such compounds and their preparation
IL90864A0 (en) Substituted 1,7-annelated 1h-indazoles,their preparation and pharmaceutical compositions containing them
IL102261A0 (en) 7-isoindolinyl-quinolone-and-naphthyridonecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
IL88989A (en) 16-dehydro-vitamin d3 derivatives, their preparation and pharmaceutical compositions containing them
IL83413A0 (en) 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
IL104356A0 (en) Benzofuranyl-and thiophenylmethylthio-alkanecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
IL92710A0 (en) 2-iminobenzothiazoline derivatives,their preparation and pharmaceutical compositions containing them
IL103292A0 (en) Cyclic-substituted imidazolyl-propenoic acid derivatives,their preparation and pharmaceutical compositions containing them
IL88002A0 (en) 2,2-dimethylchromene derivatives,their preparation and pharmaceutical compositions containing them
IL93955A0 (en) Amino acid derivatives,their preparation and pharmaceutical compositions containing them
IL91245A0 (en) Benzopyranol derivatives,their preparation and pharmaceutical compositions containing them
IL84808A0 (en) Furanuronic acid derivatives,their preparation and pharmaceutical compositions containing them
IL103291A0 (en) Imidazolyl-propenoic acid derivatives,their preparation and pharmaceutical compositions containing them
IL80658A0 (en) 6,7,8,9-tetrahydro-10-methyl-pyrido(1,2-a)indol-9-amines and derivatives thereof,their preparation and pharmaceutical compositions containing them
IL90231A0 (en) 1,1-dioxo-cephem-4-carbothiolic acid derivatives,their preparation and pharmaceutical compositions containing them
IL90002A0 (en) Phosphonoalkylpurine derivatives,their preparation and pharmaceutical compositions containing them
ZA86301B (en) 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
IL88827A (en) 5,5-dimethyl-3-styryl -2-cyclohexene-1-one oxime derivatives, their preparation and pharmaceutical compositions containing them
IL75603A0 (en) 1,3-dioxanylheptenoic acid derivatives,their preparation and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
RH Patent void