DK10190D0 - 1,1-dioxo-cephem-4-carbothiolsyrederivater - Google Patents

1,1-dioxo-cephem-4-carbothiolsyrederivater

Info

Publication number
DK10190D0
DK10190D0 DK010190A DK10190A DK10190D0 DK 10190 D0 DK10190 D0 DK 10190D0 DK 010190 A DK010190 A DK 010190A DK 10190 A DK10190 A DK 10190A DK 10190 D0 DK10190 D0 DK 10190D0
Authority
DK
Denmark
Prior art keywords
cephem
dioxo
acid derivatives
carbothiolic acid
carbothiolic
Prior art date
Application number
DK010190A
Other languages
English (en)
Other versions
DK10190A (da
Inventor
Marco Alpegiani
Pierluigi Bissolino
Ettore Perrone
Francesco Di Matteo
Piergiuseppe Orezzi
Guiseppe Cassinelli
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of DK10190D0 publication Critical patent/DK10190D0/da
Publication of DK10190A publication Critical patent/DK10190A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Peptides Or Proteins (AREA)
DK010190A 1988-05-13 1990-01-12 1,1-dioxo-cephem-4-carbothiolsyrederivater DK10190A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888811388A GB8811388D0 (en) 1988-05-13 1988-05-13 1,1-dioxo-cephem-4-carbothiolic acid derivatives
PCT/EP1989/000505 WO1989010926A1 (en) 1988-05-13 1989-05-08 1,1-dioxo-cephem-4-carbothiolic acid derivatives

Publications (2)

Publication Number Publication Date
DK10190D0 true DK10190D0 (da) 1990-01-12
DK10190A DK10190A (da) 1990-01-15

Family

ID=10636869

Family Applications (1)

Application Number Title Priority Date Filing Date
DK010190A DK10190A (da) 1988-05-13 1990-01-12 1,1-dioxo-cephem-4-carbothiolsyrederivater

Country Status (19)

Country Link
US (1) US5356888A (da)
EP (1) EP0378604B1 (da)
JP (1) JPH02504285A (da)
KR (1) KR0147300B1 (da)
AU (1) AU628821B2 (da)
DE (1) DE68913498T2 (da)
DK (1) DK10190A (da)
ES (1) ES2016017A6 (da)
FI (1) FI94642C (da)
GB (1) GB8811388D0 (da)
GR (1) GR1002249B (da)
HU (1) HU208141B (da)
IE (1) IE66309B1 (da)
IL (1) IL90231A0 (da)
NZ (1) NZ229023A (da)
PT (1) PT90530B (da)
RU (1) RU2091383C1 (da)
WO (1) WO1989010926A1 (da)
ZA (1) ZA893569B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5264429A (en) * 1989-10-06 1993-11-23 Synphar Laboratories, Inc. 2-spirocyclopropyl cephalosporin sulfone derivatives
AU661453B2 (en) * 1989-10-06 1995-07-27 Synphar Laboratories, Inc. Novel 2-spirocyclopropyl cephalosporin sulfone derivatives and processes for the preparation thereof
US5258377A (en) * 1991-04-08 1993-11-02 Taiho Pharmaceutical Co., Ltd. 2-spirocyclopropyl 4-acylcephems
US5446037A (en) * 1991-12-05 1995-08-29 Synphar Laboratories, Inc. 2-[(substituted) methylene]cephalosporin sulfones as antiinflammatory, antidegenerative and antithrombin agents
US5439904A (en) * 1993-12-07 1995-08-08 Synphar Laboratories, Inc. 2-spiro(2'-spirocycloalkyl)cyclopropyl cephalosporin sulfones as antiinflammatory and antigenerative agents
US5629306A (en) * 1994-12-09 1997-05-13 Research Corporation Technologies, Inc. 7-alkylidene cephalosporanic acid derivatives and methods of using the same
WO1997008174A1 (en) * 1995-08-31 1997-03-06 Smithkline Beecham Corporation Interleukin converting enzyme and apoptosis
US5760027A (en) * 1996-12-06 1998-06-02 Research Corporation Technologies, Inc. Use of 7-alkylidene cephalosporins to inhibit elastase activity
US6407091B1 (en) * 1999-04-15 2002-06-18 Research Corporation Technologies, Inc. β-lactamase inhibiting compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1187323A (en) * 1967-06-26 1970-04-08 Fujisawa Pharmaceutical Co Sydnone and Sydnone Imine Derivatives of 7-Aminocephalosporanic Acids and Preparation thereof
US4623645A (en) * 1983-04-18 1986-11-18 Merck & Co., Inc. Substituted cephalosporin sulfoxides as anti-inflammatory and antidegenerative agents
US4547371A (en) * 1983-04-18 1985-10-15 Merck & Co., Inc. Substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents
EP0124081A3 (en) * 1983-05-02 1986-11-26 Merck & Co. Inc. New substituted cephalosporin sulfones as antiinflammatory and antidegenerative agents, pharmaceutical compositions containing the same and processes for making them
US4699904A (en) * 1985-07-01 1987-10-13 Merck & Co., Inc. Tetrazolyl derivatives of β-lactams useful as elastase inhibitors
EP0267723B1 (en) * 1986-11-12 1996-02-07 Merck & Co. Inc. New substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents
GB8808701D0 (en) * 1988-04-13 1988-05-18 Erba Carlo Spa Beta-lactam derivatives
US5258377A (en) * 1991-04-08 1993-11-02 Taiho Pharmaceutical Co., Ltd. 2-spirocyclopropyl 4-acylcephems

Also Published As

Publication number Publication date
ZA893569B (en) 1990-01-31
DK10190A (da) 1990-01-15
NZ229023A (en) 1990-09-26
IE891550L (en) 1989-11-13
FI900145A0 (fi) 1990-01-11
WO1989010926A1 (en) 1989-11-16
HU208141B (en) 1993-08-30
HUT54166A (en) 1991-01-28
EP0378604A1 (en) 1990-07-25
FI900145A (fi) 1990-01-11
FI94642C (fi) 1995-10-10
IE66309B1 (en) 1995-12-27
ES2016017A6 (es) 1990-10-01
GB8811388D0 (en) 1988-06-15
KR0147300B1 (ko) 1998-08-17
AU628821B2 (en) 1992-09-24
JPH02504285A (ja) 1990-12-06
DE68913498D1 (en) 1994-04-07
PT90530A (pt) 1989-11-30
FI94642B (fi) 1995-06-30
IL90231A0 (en) 1989-12-15
EP0378604B1 (en) 1994-03-02
GR890100309A (el) 1990-03-12
RU2091383C1 (ru) 1997-09-27
GR1002249B (en) 1996-04-23
HU893631D0 (en) 1990-11-28
DE68913498T2 (de) 1994-06-09
KR900701800A (ko) 1990-12-04
US5356888A (en) 1994-10-18
PT90530B (pt) 1994-11-30
AU3579289A (en) 1989-11-29

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment