IL89673A0 - Novel polypeptides having growth factor activity and nucleic acid sequences encoding the polypeptides - Google Patents

Novel polypeptides having growth factor activity and nucleic acid sequences encoding the polypeptides

Info

Publication number
IL89673A0
IL89673A0 IL89673A IL8967389A IL89673A0 IL 89673 A0 IL89673 A0 IL 89673A0 IL 89673 A IL89673 A IL 89673A IL 8967389 A IL8967389 A IL 8967389A IL 89673 A0 IL89673 A0 IL 89673A0
Authority
IL
Israel
Prior art keywords
polypeptides
nucleic acid
acid sequences
growth factor
sequences encoding
Prior art date
Application number
IL89673A
Other languages
English (en)
Original Assignee
Oncogen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogen filed Critical Oncogen
Publication of IL89673A0 publication Critical patent/IL89673A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
IL89673A 1988-03-24 1989-03-20 Novel polypeptides having growth factor activity and nucleic acid sequences encoding the polypeptides IL89673A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17265388A 1988-03-24 1988-03-24

Publications (1)

Publication Number Publication Date
IL89673A0 true IL89673A0 (en) 1989-09-28

Family

ID=22628611

Family Applications (1)

Application Number Title Priority Date Filing Date
IL89673A IL89673A0 (en) 1988-03-24 1989-03-20 Novel polypeptides having growth factor activity and nucleic acid sequences encoding the polypeptides

Country Status (22)

Country Link
JP (1) JPH0279981A (el)
KR (1) KR890014743A (el)
AU (2) AU3169589A (el)
BE (1) BE1004202A5 (el)
CH (1) CH681081A5 (el)
DE (1) DE3910084A1 (el)
DK (1) DK146789A (el)
ES (1) ES2013408A6 (el)
FI (1) FI891308A (el)
FR (1) FR2632321A1 (el)
GB (1) GB2219799B (el)
GR (1) GR1000876B (el)
HU (1) HUT50501A (el)
IE (1) IE890950L (el)
IL (1) IL89673A0 (el)
IT (1) IT1234961B (el)
LU (1) LU87489A1 (el)
NL (1) NL8900724A (el)
NO (1) NO891273D0 (el)
NZ (1) NZ228427A (el)
PT (1) PT90118B (el)
SE (1) SE8901031L (el)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0293785A3 (en) * 1987-05-29 1990-05-02 Oncogen Limited Partnership Cloning and expression of simian transforming growth factor-ss1
CA2037440A1 (en) * 1990-03-02 1991-09-03 Gregory D. Plowman Her3: a novel egf receptor homolog
EP0739984A1 (en) * 1995-04-26 1996-10-30 San Tumorforschungs-Gmbh Bivalent polypeptides containing at least two domains
US6852506B1 (en) 1996-04-10 2005-02-08 Human Genome Sciences, Inc. Extracellular/epidermal growth factor-like protein
AU5549296A (en) * 1996-04-10 1997-10-29 Human Genome Sciences, Inc. Extracellular/epidermal growth factor-like protein

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983004030A1 (en) * 1982-05-06 1983-11-24 Applied Molecular Genetics, Inc. The manufacture and expression of genes for urogastrone and polypeptide analogs thereof
JPS6028994A (ja) * 1983-07-08 1985-02-14 Wakunaga Seiyaku Kk 〔２１―ロイシン〕ヒトウロガストロン
WO1985002198A1 (en) * 1983-11-01 1985-05-23 Amgen Microbial expression of type i transforming growth factor, polypeptide analogs thereof and hybrid egf/tgf polypeptides
JP2554459B2 (ja) * 1984-07-02 1996-11-13 アース製薬 株式会社 β−ウロガストロン遺伝子、対応プラスミド組換体及び対応形質転換体
JPS62501071A (ja) * 1984-10-30 1987-04-30 オンコゲン 成長因子活性を有する新規なポリペプチド及び該ポリペプチドをコ−ドする核酸配列
GB8507666D0 (en) * 1985-03-25 1985-05-01 Wellcome Found Epidermal growth factor production
US4743679A (en) * 1986-02-24 1988-05-10 Creative Biomolecules, Inc. Process for producing human epidermal growth factor and analogs thereof
GB2210618B (en) * 1987-10-08 1991-10-16 British Bio Technology Synthetic egf gene
ES2081801T3 (es) * 1987-10-30 1996-03-16 Bristol Myers Squibb Co Plasmidos de expresion.
WO1989003886A1 (en) * 1987-10-30 1989-05-05 Oncogen, A Limited Partnership Expression systems for preparation of polypeptides in prokaryotic cells

Also Published As

Publication number Publication date
SE8901031D0 (sv) 1989-03-22
DE3910084A1 (de) 1989-11-16
SE8901031L (sv) 1989-09-25
FI891308A0 (fi) 1989-03-20
DK146789A (da) 1989-09-25
DK146789D0 (da) 1989-03-22
IT1234961B (it) 1992-06-09
IE890950L (en) 1989-09-24
ES2013408A6 (es) 1990-05-01
KR890014743A (ko) 1989-10-25
NZ228427A (en) 1993-03-26
PT90118A (pt) 1989-11-10
GB8906758D0 (en) 1989-05-10
NO891273D0 (no) 1989-03-22
GB2219799B (en) 1992-10-14
BE1004202A5 (fr) 1992-10-13
AU3169589A (en) 1989-09-28
NL8900724A (nl) 1989-10-16
FI891308A (fi) 1989-09-25
FR2632321A1 (fr) 1989-12-08
IT8919917A0 (it) 1989-03-24
CH681081A5 (el) 1993-01-15
JPH0279981A (ja) 1990-03-20
PT90118B (pt) 1994-07-29
GR890100185A (en) 1990-01-19
LU87489A1 (fr) 1989-10-26
AU2990492A (en) 1993-03-04
GR1000876B (el) 1993-03-16
HUT50501A (en) 1990-02-28
GB2219799A (en) 1989-12-20

Similar Documents

Publication Publication Date Title
GB8819209D0 (en) Polypeptide & dna encoding same
GB2181433B (en) Protein modification with peg
IL81839A0 (en) Polypeptide,dna and its use
IL86455A0 (en) Polypeptide and production thereof
EP0429544A4 (en) Synthetic, anti-complement protein and the gene encoding same
IL85372A0 (en) Peptides with laminin-like activity
GB8823068D0 (en) Recombinant dna
ZA886314B (en) Polypeptides with fibronectin activity
EP0329413A3 (en) Polypeptides with cell-spreading activity
IL89673A0 (en) Novel polypeptides having growth factor activity and nucleic acid sequences encoding the polypeptides
PH24603A (en) Novel polypeptides having growth factor activity and nucleic acid sequences encoding the polypeptides
GB8929110D0 (en) Polypeptides and dna encoding therefor
EP0286114A3 (en) Reg gene and protein encoded by the gene
GB8818150D0 (en) Gene modification
GB2218420B (en) Synthetic gene encoding interleukin 4
GB8818775D0 (en) Synthetic gene
GB2223495B (en) Synthetic gene encoding basic fibroblast growth factor
IE852704L (en) Novel polypeptides having growth factor activity and¹nucleic acid sequences encoding the polypeptides
GB8808523D0 (en) Synthetic gene
GB8808205D0 (en) Synthetic gene
GB8808524D0 (en) Synthetic gene
IE870674L (en) Polypeptide, dna and its use
GB8716938D0 (en) Dna sequence coding
IE881177L (en) Recombinant dna
ZA895536B (en) Peptide and dna sequences