IL89388A - Preparations containing reliable idols are converted to halogen, several such compounds and a process for their preparation - Google Patents
Preparations containing reliable idols are converted to halogen, several such compounds and a process for their preparationInfo
- Publication number
- IL89388A IL89388A IL8938889A IL8938889A IL89388A IL 89388 A IL89388 A IL 89388A IL 8938889 A IL8938889 A IL 8938889A IL 8938889 A IL8938889 A IL 8938889A IL 89388 A IL89388 A IL 89388A
- Authority
- IL
- Israel
- Prior art keywords
- group
- chloro
- hydrogen
- allylamine
- fluoro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
- Pyrrole Compounds (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16038288A | 1988-02-25 | 1988-02-25 | |
| US16036488A | 1988-02-25 | 1988-02-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL89388A true IL89388A (en) | 1995-03-15 |
Family
ID=26856831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL8938889A IL89388A (en) | 1988-02-25 | 1989-02-23 | Preparations containing reliable idols are converted to halogen, several such compounds and a process for their preparation |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0330218B1 (fr) |
| JP (1) | JP2772660B2 (fr) |
| KR (1) | KR890012641A (fr) |
| CN (1) | CN1035497A (fr) |
| AT (1) | ATE117549T1 (fr) |
| AU (1) | AU618076B2 (fr) |
| CA (1) | CA1338647C (fr) |
| DE (1) | DE68920757T2 (fr) |
| DK (1) | DK89489A (fr) |
| ES (1) | ES2070134T3 (fr) |
| FI (1) | FI890827A (fr) |
| GR (1) | GR3015470T3 (fr) |
| IE (1) | IE65553B1 (fr) |
| IL (1) | IL89388A (fr) |
| NO (1) | NO890801L (fr) |
| NZ (1) | NZ228068A (fr) |
| PT (1) | PT89839B (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8426587B2 (en) | 2007-11-21 | 2013-04-23 | Pharmaxis Ltd. | Haloallylamine inhibitors of SSAO/VAP-1 and uses therefor |
| MX2017011269A (es) * | 2015-03-06 | 2018-01-12 | Pharmakea Inc | Inhibidores de lisil oxidasa tipo 2 fluorinados y usos de los mismos. |
| GB201602934D0 (en) | 2016-02-19 | 2016-04-06 | Cancer Res Inst Royal | Compounds |
| WO2018157190A1 (fr) * | 2017-03-02 | 2018-09-07 | Pharmaxis Ltd. | Inhibiteurs de lysyl oxydases dérivés d'halogénoallylamine pyrazole et leurs utilisations |
| GB201809295D0 (en) | 2018-06-06 | 2018-07-25 | Institute Of Cancer Res Royal Cancer Hospital | Lox inhibitors |
| GB201818750D0 (en) | 2018-11-16 | 2019-01-02 | Institute Of Cancer Res Royal Cancer Hospital | Lox inhibitors |
| WO2024044813A1 (fr) * | 2022-08-29 | 2024-03-07 | Pharmaxis Ltd. | Nouveaux inhibiteurs sélectifs de lysyl oxydases |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2891064A (en) * | 1956-05-28 | 1959-06-16 | Dow Chemical Co | 3, 3-dichloro-2-methylallylamines |
| US4454158A (en) * | 1981-06-01 | 1984-06-12 | Merrell Toraude Et Compagnie | Allyl amine MAO inhibitors |
| US4650907A (en) * | 1985-12-05 | 1987-03-17 | Merrell Dow Pharmaceuticals Inc. | Nonaromatic fluoroallylamine MAO inhibitors |
| DD246990A1 (de) * | 1986-02-26 | 1987-06-24 | Univ Leipzig | Verfahren zur herstellung von gamma-chlorallylverbindungen aus polychloralkanen |
-
1989
- 1989-02-21 NZ NZ228068A patent/NZ228068A/xx unknown
- 1989-02-21 AU AU30160/89A patent/AU618076B2/en not_active Ceased
- 1989-02-21 CA CA000591677A patent/CA1338647C/fr not_active Expired - Fee Related
- 1989-02-21 FI FI890827A patent/FI890827A/fi not_active Application Discontinuation
- 1989-02-23 IL IL8938889A patent/IL89388A/en not_active IP Right Cessation
- 1989-02-23 JP JP1042011A patent/JP2772660B2/ja not_active Expired - Lifetime
- 1989-02-24 IE IE61289A patent/IE65553B1/en not_active IP Right Cessation
- 1989-02-24 KR KR1019890002189A patent/KR890012641A/ko not_active Application Discontinuation
- 1989-02-24 DK DK089489A patent/DK89489A/da not_active Application Discontinuation
- 1989-02-24 AT AT89103247T patent/ATE117549T1/de not_active IP Right Cessation
- 1989-02-24 PT PT89839A patent/PT89839B/pt active IP Right Grant
- 1989-02-24 EP EP89103247A patent/EP0330218B1/fr not_active Expired - Lifetime
- 1989-02-24 DE DE68920757T patent/DE68920757T2/de not_active Expired - Fee Related
- 1989-02-24 NO NO89890801A patent/NO890801L/no unknown
- 1989-02-24 ES ES89103247T patent/ES2070134T3/es not_active Expired - Lifetime
- 1989-02-25 CN CN89101156A patent/CN1035497A/zh active Pending
-
1995
- 1995-03-20 GR GR950400601T patent/GR3015470T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT89839A (pt) | 1989-10-04 |
| CA1338647C (fr) | 1996-10-15 |
| DK89489D0 (da) | 1989-02-24 |
| DK89489A (da) | 1989-08-26 |
| JPH023626A (ja) | 1990-01-09 |
| ATE117549T1 (de) | 1995-02-15 |
| DE68920757D1 (de) | 1995-03-09 |
| EP0330218A3 (fr) | 1992-01-02 |
| EP0330218A2 (fr) | 1989-08-30 |
| DE68920757T2 (de) | 1995-06-08 |
| EP0330218B1 (fr) | 1995-01-25 |
| IE890612L (en) | 1989-08-25 |
| NZ228068A (en) | 1991-11-26 |
| AU3016089A (en) | 1989-08-31 |
| NO890801D0 (no) | 1989-02-24 |
| ES2070134T3 (es) | 1995-06-01 |
| FI890827A0 (fi) | 1989-02-21 |
| KR890012641A (ko) | 1989-09-18 |
| AU618076B2 (en) | 1991-12-12 |
| CN1035497A (zh) | 1989-09-13 |
| IE65553B1 (en) | 1995-11-01 |
| JP2772660B2 (ja) | 1998-07-02 |
| GR3015470T3 (en) | 1995-06-30 |
| FI890827A (fi) | 1989-08-26 |
| NO890801L (no) | 1989-08-28 |
| PT89839B (pt) | 1994-04-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US5021456A (en) | Inhibitors of lysyl oxidase | |
| US4965288A (en) | Inhibitors of lysyl oxidase | |
| US5182297A (en) | Inhibitors of lysyl oxidase | |
| US5252608A (en) | Inhibitors of lysyl oxidase | |
| US4943593A (en) | Inhibitors of lysyl oxidase | |
| US5059714A (en) | Inhibitors of lysyl oxidase | |
| US5120764A (en) | Inhibitors of lysyl oxidase | |
| AU782759B2 (en) | Composition comprising a tramadol material and an anticonvulsant drug | |
| EP0678026B1 (fr) | Application de la carbamazepine et de l'oxcarbazepine dans le traitement de la maladie de parkinson et des syndromes parkinsoniens | |
| US7902251B2 (en) | Method for treating pain | |
| EP1415667B1 (fr) | Regulateurs de la secretion de suc pancreatique comprenant un agent de regulation du recepteur a lpa | |
| IL89388A (en) | Preparations containing reliable idols are converted to halogen, several such compounds and a process for their preparation | |
| JP2001506978A (ja) | 置換１―［２［ビス（アリール）メトキシ］エチル］―ピペラジンおよび―ホモピペラジンのヒドロキシル化類似物の持続性放出誘導体およびそのドパミン再アップテイクの非競合的拮抗物質としての使用 | |
| US20070088073A1 (en) | Method for treating pain | |
| JPH10511978A (ja) | アルツハイマー病の治療用薬剤 | |
| WO2008020651A1 (fr) | antagoniste de récepteur P2X4 | |
| KR101701943B1 (ko) | 당뇨병의 치료 또는 예방약 | |
| US20070105940A1 (en) | Method for treating pain | |
| US20070259945A1 (en) | Method for treating pain | |
| RU2349587C2 (ru) | Производное фенилуксусной кислоты и его применение | |
| FR2763847A1 (fr) | Utilisation de tetrahydropyridines 4-substituees pour fabriquer des medicaments agissant sur le tgf-beta-1 | |
| JP6461922B2 (ja) | アミロイド線維形成の抑制又は阻害剤 | |
| MXPA06004390A (es) | Tratamiento de combinacion de obesidad que implica derivados de 4,5-dihidro-1h-pirazol que tienen actividad antagonista de cb1 e inhibidores de lipasa. | |
| GB2413322A (en) | Nefopam analogues | |
| Dąbrowska-Maś et al. | New approaches to the synthesis of diclofenac choline |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| RH1 | Patent not in force | ||
| HC | Change of name of proprietor(s) |
Owner name: AVENTIS INC. Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC. |