NO890801D0 - Fremgangsmaate for fremstilling av lysyloxydaseinhibitorer. - Google Patents

Fremgangsmaate for fremstilling av lysyloxydaseinhibitorer.

Info

Publication number
NO890801D0
NO890801D0 NO890801A NO890801A NO890801D0 NO 890801 D0 NO890801 D0 NO 890801D0 NO 890801 A NO890801 A NO 890801A NO 890801 A NO890801 A NO 890801A NO 890801 D0 NO890801 D0 NO 890801D0
Authority
NO
Norway
Prior art keywords
inhibitors
lysyloxydase
procedure
preparation
collagen
Prior art date
Application number
NO890801A
Other languages
English (en)
Other versions
NO890801L (no
Inventor
Michael G Palfreyman
Ian A Mcdonald
Philippe Bey
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of NO890801D0 publication Critical patent/NO890801D0/no
Publication of NO890801L publication Critical patent/NO890801L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/62Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Furan Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO89890801A 1988-02-25 1989-02-24 Fremgangsmaate for fremstilling av lysyloxydaseinhibitorer. NO890801L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16038288A 1988-02-25 1988-02-25
US16036488A 1988-02-25 1988-02-25

Publications (2)

Publication Number Publication Date
NO890801D0 true NO890801D0 (no) 1989-02-24
NO890801L NO890801L (no) 1989-08-28

Family

ID=26856831

Family Applications (1)

Application Number Title Priority Date Filing Date
NO89890801A NO890801L (no) 1988-02-25 1989-02-24 Fremgangsmaate for fremstilling av lysyloxydaseinhibitorer.

Country Status (17)

Country Link
EP (1) EP0330218B1 (no)
JP (1) JP2772660B2 (no)
KR (1) KR890012641A (no)
CN (1) CN1035497A (no)
AT (1) ATE117549T1 (no)
AU (1) AU618076B2 (no)
CA (1) CA1338647C (no)
DE (1) DE68920757T2 (no)
DK (1) DK89489A (no)
ES (1) ES2070134T3 (no)
FI (1) FI890827A (no)
GR (1) GR3015470T3 (no)
IE (1) IE65553B1 (no)
IL (1) IL89388A (no)
NO (1) NO890801L (no)
NZ (1) NZ228068A (no)
PT (1) PT89839B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101917845A (zh) 2007-11-21 2010-12-15 法马克西斯制药公司 Ssao/vap-1的卤代烯丙胺抑制剂及其用途
MX2017011269A (es) * 2015-03-06 2018-01-12 Pharmakea Inc Inhibidores de lisil oxidasa tipo 2 fluorinados y usos de los mismos.
GB201602934D0 (en) 2016-02-19 2016-04-06 Cancer Res Inst Royal Compounds
WO2018157190A1 (en) * 2017-03-02 2018-09-07 Pharmaxis Ltd. Haloallylamine pyrazole derivative inhibitors of lysyl oxidases and uses thereof
GB201809295D0 (en) 2018-06-06 2018-07-25 Institute Of Cancer Res Royal Cancer Hospital Lox inhibitors
GB201818750D0 (en) 2018-11-16 2019-01-02 Institute Of Cancer Res Royal Cancer Hospital Lox inhibitors
WO2024044813A1 (en) * 2022-08-29 2024-03-07 Pharmaxis Ltd. Novel selective inhibitors of lysyl oxidases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2891064A (en) * 1956-05-28 1959-06-16 Dow Chemical Co 3, 3-dichloro-2-methylallylamines
US4454158A (en) * 1981-06-01 1984-06-12 Merrell Toraude Et Compagnie Allyl amine MAO inhibitors
US4650907A (en) * 1985-12-05 1987-03-17 Merrell Dow Pharmaceuticals Inc. Nonaromatic fluoroallylamine MAO inhibitors
DD246990A1 (de) * 1986-02-26 1987-06-24 Univ Leipzig Verfahren zur herstellung von gamma-chlorallylverbindungen aus polychloralkanen

Also Published As

Publication number Publication date
GR3015470T3 (en) 1995-06-30
NO890801L (no) 1989-08-28
NZ228068A (en) 1991-11-26
AU3016089A (en) 1989-08-31
CN1035497A (zh) 1989-09-13
EP0330218A2 (en) 1989-08-30
FI890827A (fi) 1989-08-26
JPH023626A (ja) 1990-01-09
IL89388A (en) 1995-03-15
JP2772660B2 (ja) 1998-07-02
EP0330218B1 (en) 1995-01-25
ES2070134T3 (es) 1995-06-01
DK89489D0 (da) 1989-02-24
DE68920757D1 (de) 1995-03-09
IE65553B1 (en) 1995-11-01
KR890012641A (ko) 1989-09-18
DK89489A (da) 1989-08-26
PT89839B (pt) 1994-04-29
IE890612L (en) 1989-08-25
EP0330218A3 (en) 1992-01-02
FI890827A0 (fi) 1989-02-21
DE68920757T2 (de) 1995-06-08
ATE117549T1 (de) 1995-02-15
PT89839A (pt) 1989-10-04
AU618076B2 (en) 1991-12-12
CA1338647C (en) 1996-10-15

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