IL88664A - Heterocyclic-substituted quinoline and naphthyridine-carboxylic acids - Google Patents

Heterocyclic-substituted quinoline and naphthyridine-carboxylic acids

Info

Publication number
IL88664A
IL88664A IL88664A IL8866488A IL88664A IL 88664 A IL88664 A IL 88664A IL 88664 A IL88664 A IL 88664A IL 8866488 A IL8866488 A IL 8866488A IL 88664 A IL88664 A IL 88664A
Authority
IL
Israel
Prior art keywords
heterocyclic
carboxylic acids
naphthyridine
substituted quinoline
substituted
Prior art date
Application number
IL88664A
Other languages
English (en)
Other versions
IL88664A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL88664A0 publication Critical patent/IL88664A0/xx
Publication of IL88664A publication Critical patent/IL88664A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Quinoline Compounds (AREA)
IL88664A 1987-12-18 1988-12-12 Heterocyclic-substituted quinoline and naphthyridine-carboxylic acids IL88664A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1987/003412 WO1989005643A1 (en) 1987-12-18 1987-12-18 Heterocyclic-substituted quinoline-carboxylic acids

Publications (2)

Publication Number Publication Date
IL88664A0 IL88664A0 (en) 1989-07-31
IL88664A true IL88664A (en) 1993-08-18

Family

ID=22202722

Family Applications (1)

Application Number Title Priority Date Filing Date
IL88664A IL88664A (en) 1987-12-18 1988-12-12 Heterocyclic-substituted quinoline and naphthyridine-carboxylic acids

Country Status (18)

Country Link
US (1) US5037834A (da)
EP (1) EP0321191B1 (da)
JP (1) JPH0725757B2 (da)
KR (1) KR900008568B1 (da)
AT (1) ATE113599T1 (da)
AU (1) AU600188B2 (da)
DE (1) DE3852010T2 (da)
DK (1) DK699788A (da)
ES (1) ES2061695T3 (da)
FI (1) FI90239C (da)
IE (1) IE65732B1 (da)
IL (1) IL88664A (da)
MY (1) MY104072A (da)
NO (1) NO178149C (da)
NZ (1) NZ227357A (da)
PT (1) PT89222B (da)
WO (1) WO1989005643A1 (da)
ZA (1) ZA889395B (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0251308B1 (de) * 1986-07-04 1990-11-22 Chemie Linz Gesellschaft m.b.H. 4-Chinolon-3-carbonsäurederivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
DE3853654T2 (de) * 1987-08-14 1996-01-18 Asahi Glass Co Ltd Fluorierte Benzoylverbindungen.
US5093515A (en) * 1987-08-14 1992-03-03 Asahi Glass Company Ltd. Fluorinated benzoyl compounds
US5214051A (en) * 1989-08-01 1993-05-25 Pfizer Inc. Thiazolyl and oxazolyl[5,4-c]piperidyl-substituted quinolone-carboxylic acid and related analogs thereof having antibacterial properties are disclosed
KR910009333B1 (ko) * 1989-10-23 1991-11-11 재단법인 한국화학연구소 항균작용을 갖는 퀴놀린계 화합물과 그의 제조방법
KR910009330B1 (ko) * 1989-10-23 1991-11-11 재단법인 한국화학연구소 항균작용을 갖는 퀴놀린계 화합물과 그의 제조방법
DE4121214A1 (de) * 1991-06-27 1993-01-14 Bayer Ag 7-azaisoindolinyl-chinolon- und -naphthyridoncarbonsaeure-derivate
DE4342186A1 (de) * 1993-12-10 1995-06-14 Bayer Ag Eintopfverfahren zur Herstellung von 3-Chinoloncarbonsäurederivaten
DE19652239A1 (de) 1996-12-16 1998-06-18 Bayer Ag Verwendung von 7-(2-Oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-chinolon- und -naphthyridoncarbonsäure-Derivaten zur Therapie von Helicobacter-pylori-Infektionen und den damit assoziierten gastroduodenalen Erkrankungen
US6608081B2 (en) * 1999-08-12 2003-08-19 Ortho-Mcneil Pharmaceutical, Inc. Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
US6855385B2 (en) * 2000-05-31 2005-02-15 Ttm Advanced Circuits, Inc. PCB support plate for PCB via fill
CN1250544C (zh) * 2001-02-07 2006-04-12 奥索-麦克尼尔药品公司 吡啶并芳基苯基噁唑烷酮抗菌剂和相关组合物及方法
JP2006505625A (ja) * 2002-09-26 2006-02-16 ファイザー・インク Hiv感染症を治療するためのピラゾールアミド
CL2004000553A1 (es) * 2003-03-20 2005-02-04 Actelion Pharmaceuticals Ltd Uso de compuestos derivados de guanidina como antagonistas del receptor de neuropeptido ff; compuestos derivados de guanidina; procedimientos de preparacion; y composicion farmaceutica que los comprende.
GB0610804D0 (en) * 2006-05-31 2006-07-12 Portela & Ca Sa New crystal forms
ATE488520T1 (de) * 2006-08-04 2010-12-15 Merz Pharma Gmbh & Co Kgaa Pyrazolopyrimidine, ein verfahren zu ihrer herstellung und ihre verwendung als medizin
JP2011506315A (ja) * 2007-12-05 2011-03-03 バイアル−ポルテラ アンド シーエー,エス.エー. 新たな塩、及び結晶形
KR101996697B1 (ko) * 2011-08-31 2019-07-04 오쓰까 세이야꾸 가부시키가이샤 퀴놀론 화합물
TWI695000B (zh) * 2017-10-29 2020-06-01 中國醫藥大學 用於抑制adam9活性之化合物、其醫藥組合物及其用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
JPS53141286A (en) * 1977-05-16 1978-12-08 Kyorin Seiyaku Kk Novel substituted quinolinecarboxylic acid
JPS5746986A (en) * 1980-09-02 1982-03-17 Dai Ichi Seiyaku Co Ltd Pyrido(1,2,3-de)(1,4)benzoxazine derivative
US4665079A (en) * 1984-02-17 1987-05-12 Warner-Lambert Company Antibacterial agents
IE55898B1 (en) * 1982-09-09 1991-02-14 Warner Lambert Co Antibacterial agents
JPS59128383A (ja) * 1982-12-29 1984-07-24 Kanebo Ltd 新規キノリンカルボン酸誘導体および該化合物を有効成分とする抗菌剤
JPS59204194A (ja) * 1983-05-09 1984-11-19 Hokuriku Seiyaku Co Ltd 7−ジアザビシクロアルカン置換−6,8−ジフオロ−4−オキソ−1,4−ジヒドロキノリン−3−カルボン酸誘導体
GB8333798D0 (en) * 1983-12-19 1984-01-25 Fujisawa Pharmaceutical Co Quinolone compounds
US4571396A (en) * 1984-04-16 1986-02-18 Warner-Lambert Company Antibacterial agents
US4636506A (en) * 1984-12-06 1987-01-13 Pfizer, Inc. 7-heterocyclic-1,4-dihydroquinolones
US4657913A (en) * 1985-04-18 1987-04-14 Warner-Lambert Company Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents
DE3519286A1 (de) * 1985-05-30 1986-12-04 Bayer Ag, 5090 Leverkusen 7-azolyl-1-cyclopropyl-1,4-dihydro-4-oxo-3- chinolincarbonsaeuren und -1,8-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
IN166416B (da) * 1985-09-18 1990-05-05 Pfizer

Also Published As

Publication number Publication date
NO893305D0 (no) 1989-08-17
ATE113599T1 (de) 1994-11-15
DK699788A (da) 1989-08-11
KR890009925A (ko) 1989-08-04
NZ227357A (en) 1991-04-26
FI90239B (fi) 1993-09-30
NO178149C (no) 1996-01-31
NO178149B (no) 1995-10-23
US5037834A (en) 1991-08-06
FI893883A (fi) 1989-08-17
KR900008568B1 (ko) 1990-11-24
NO893305L (no) 1989-10-17
IE883763L (en) 1989-06-18
AU2698788A (en) 1989-06-22
EP0321191B1 (en) 1994-11-02
EP0321191A2 (en) 1989-06-21
IE65732B1 (en) 1995-11-15
PT89222A (pt) 1989-12-29
EP0321191A3 (en) 1991-02-27
ZA889395B (en) 1990-08-29
DK699788D0 (da) 1988-12-16
ES2061695T3 (es) 1994-12-16
PT89222B (pt) 1994-11-30
AU600188B2 (en) 1990-08-02
FI893883A0 (fi) 1989-08-17
DE3852010D1 (de) 1994-12-08
DE3852010T2 (de) 1995-03-09
MY104072A (en) 1993-11-30
WO1989005643A1 (en) 1989-06-29
IL88664A0 (en) 1989-07-31
JPH01211587A (ja) 1989-08-24
JPH0725757B2 (ja) 1995-03-22
FI90239C (fi) 1994-01-10

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