IL88047A - Aminomethyl oxooxazolidinyl aroylbenzene derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Aminomethyl oxooxazolidinyl aroylbenzene derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL88047A
IL88047A IL88047A IL8804788A IL88047A IL 88047 A IL88047 A IL 88047A IL 88047 A IL88047 A IL 88047A IL 8804788 A IL8804788 A IL 8804788A IL 88047 A IL88047 A IL 88047A
Authority
IL
Israel
Prior art keywords
aroylbenzene
derivatives
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL88047A
Other languages
English (en)
Other versions
IL88047A0 (en
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Publication of IL88047A0 publication Critical patent/IL88047A0/xx
Publication of IL88047A publication Critical patent/IL88047A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL88047A 1987-10-16 1988-10-14 Aminomethyl oxooxazolidinyl aroylbenzene derivatives,their preparation and pharmaceutical compositions containing them IL88047A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10903287A 1987-10-16 1987-10-16

Publications (2)

Publication Number Publication Date
IL88047A0 IL88047A0 (en) 1989-06-30
IL88047A true IL88047A (en) 1992-11-15

Family

ID=22325458

Family Applications (1)

Application Number Title Priority Date Filing Date
IL88047A IL88047A (en) 1987-10-16 1988-10-14 Aminomethyl oxooxazolidinyl aroylbenzene derivatives,their preparation and pharmaceutical compositions containing them

Country Status (20)

Country Link
EP (1) EP0312000B1 (xx)
JP (1) JPH01132570A (xx)
KR (1) KR890006602A (xx)
AT (1) ATE73783T1 (xx)
AU (1) AU617366B2 (xx)
CA (1) CA1320730C (xx)
DE (1) DE3869310D1 (xx)
DK (1) DK573988A (xx)
ES (1) ES2033394T3 (xx)
FI (1) FI884755A (xx)
GR (1) GR3004973T3 (xx)
HU (1) HU199810B (xx)
IE (1) IE60426B1 (xx)
IL (1) IL88047A (xx)
MY (1) MY103784A (xx)
NO (1) NO174551C (xx)
NZ (1) NZ226582A (xx)
PT (1) PT88765B (xx)
SU (1) SU1616517A3 (xx)
ZA (1) ZA887683B (xx)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
US5231188A (en) * 1989-11-17 1993-07-27 The Upjohn Company Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents
EP0610265B1 (en) * 1991-11-01 1996-12-27 PHARMACIA & UPJOHN COMPANY Substituted aryl- and heteroarylphenyloxazolidinones useful as antibacterial agents
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
DE69316240T2 (de) * 1992-12-08 1998-05-20 Upjohn Co Durch eine tropon gruppe substituierte phenyloxazolidinone-derivate als antibakterielles mittel
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
JP3698724B2 (ja) * 1993-11-22 2005-09-21 ファルマシア・アンド・アップジョン・カンパニー 置換−ヒドロキシアセチルピペラジンフェニルオキサゾリジノンのエステル
DE4425613A1 (de) * 1994-07-20 1996-01-25 Bayer Ag 5-gliedrige Heteroaryl-oxazolidinone
DE4425612A1 (de) * 1994-07-20 1996-04-04 Bayer Ag 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
DE4425609A1 (de) * 1994-07-20 1996-01-25 Bayer Ag Benzofuranyl- und Benzothienyloxazolidinone
DE19514313A1 (de) 1994-08-03 1996-02-08 Bayer Ag Benzoxazolyl- und Benzothiazolyloxazolidinone
US5952324A (en) * 1994-11-15 1999-09-14 Pharmacia & Upjohn Company Bicyclic oxazine and thiazine oxazolidinone antibacterials
DK0807112T3 (da) * 1995-02-03 2001-12-17 Upjohn Co Antimikrobiel heteroaromatisk ringsubstitueret phenyloxazolidinon
HRP960159A2 (en) * 1995-04-21 1997-08-31 Bayer Ag Benzocyclopentane oxazolidinones containing heteroatoms
PT828741E (pt) * 1995-05-11 2002-02-28 Upjohn Co Oxazolidinonas de diazinilo espirociclico e biciclico e de carbazinilo
MX9703040A (es) * 1995-09-12 1997-07-31 Upjohn Co Antimicrobianos de feniloxazolidinona.
DE19601265A1 (de) * 1996-01-16 1997-07-17 Bayer Ag 2-Oxo- und 2-Thio-1,2-dihydrochinolinyl-oxazolidinone
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
DE19604223A1 (de) 1996-02-06 1997-08-07 Bayer Ag Neue substituierte Oxazolidinone
HRP970049A2 (en) 1996-02-06 1998-04-30 Bayer Ag New heteroaryl oxazolidinones
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
EP1007525A1 (en) * 1997-08-29 2000-06-14 Zeneca Limited Aminometyl oxooxazolidinyl benzene derivatives
HUP0100470A3 (en) * 1997-11-12 2002-08-28 Upjohn Co Oxazolidinone derivatives and pharmaceutical compositions containing them
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
US6562844B2 (en) 1998-01-23 2003-05-13 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
AU764184B2 (en) * 1998-01-23 2003-08-14 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US7002020B1 (en) 1998-01-23 2006-02-21 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
WO2000029396A1 (de) * 1998-11-17 2000-05-25 Bayer Aktiengesellschaft Neue substituierte phenyloxazolidon-derivate
PL363960A1 (en) 2000-07-17 2004-11-29 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
US6956040B2 (en) 2001-07-16 2005-10-18 Ranbaxy Laboratories Limited Oxazolidinone piperazinyl derivatives as potential antimicrobials
KR100854211B1 (ko) 2003-12-18 2008-08-26 동아제약주식회사 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물
CN101220002B (zh) * 2007-12-28 2011-07-13 天津药物研究院 作为抗菌剂的噁唑烷酮类化合物
KR101023174B1 (ko) * 2008-09-24 2011-03-18 주식회사 레고켐 바이오사이언스 사이클릭 아미독심 또는 사이클릭 아미드라존 기를 가지는 신규한 옥사졸리디논 유도체 및 이를 함유하는 의약 조성물
CN106220621B (zh) 2008-10-10 2019-06-11 默沙东公司 制备噁唑烷酮类的方法及含有噁唑烷酮类的组合物
NZ594408A (en) 2009-02-03 2014-03-28 Trius Therapeutics Crystalline form of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate
US8580767B2 (en) 2009-05-28 2013-11-12 Trius Therapeutics, Inc. Oxazolidinone containing dimer compounds, compositions and methods to make and use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1222708A (en) * 1968-10-22 1971-02-17 Delalande Sa Novel 5-(n-substituted aminomethyl)-2-oxazolidinones and their process of preparation
FR2500450A1 (fr) * 1981-02-25 1982-08-27 Delalande Sa Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique
ES8506659A1 (es) * 1983-06-07 1985-08-01 Du Pont Un procedimiento para la preparacion de nuevos derivados del amino-metil-oxooxazolidinil-benzeno.
CA1260948A (en) * 1984-12-05 1989-09-26 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents

Also Published As

Publication number Publication date
HU199810B (en) 1990-03-28
FI884755A0 (fi) 1988-10-14
IL88047A0 (en) 1989-06-30
GR3004973T3 (xx) 1993-04-28
AU617366B2 (en) 1991-11-28
EP0312000B1 (en) 1992-03-18
AU2396288A (en) 1989-04-20
PT88765B (pt) 1992-12-31
DE3869310D1 (de) 1992-04-23
DK573988A (da) 1989-04-17
NO174551C (no) 1994-05-25
IE60426B1 (en) 1994-07-13
IE883119L (en) 1989-04-16
NO884594L (no) 1989-04-17
NO884594D0 (no) 1988-10-14
SU1616517A3 (ru) 1990-12-23
NZ226582A (en) 1990-06-26
ES2033394T3 (es) 1993-03-16
KR890006602A (ko) 1989-06-14
HUT49864A (en) 1989-11-28
EP0312000A1 (en) 1989-04-19
CA1320730C (en) 1993-07-27
ZA887683B (en) 1990-06-27
JPH01132570A (ja) 1989-05-25
DK573988D0 (da) 1988-10-14
MY103784A (en) 1993-09-30
NO174551B (no) 1994-02-14
FI884755A (fi) 1989-04-17
ATE73783T1 (de) 1992-04-15

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