IL87894A - Esters of 71-carboxylic acid adendrostane, their preparation and pharmaceutical preparations containing them - Google Patents

Esters of 71-carboxylic acid adendrostane, their preparation and pharmaceutical preparations containing them

Info

Publication number
IL87894A
IL87894A IL8789488A IL8789488A IL87894A IL 87894 A IL87894 A IL 87894A IL 8789488 A IL8789488 A IL 8789488A IL 8789488 A IL8789488 A IL 8789488A IL 87894 A IL87894 A IL 87894A
Authority
IL
Israel
Prior art keywords
group
androstane
carboxylic acid
methyl
hydroxy
Prior art date
Application number
IL8789488A
Other languages
English (en)
Hebrew (he)
Other versions
IL87894A0 (en
Original Assignee
Norwich Eaton Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norwich Eaton Pharma filed Critical Norwich Eaton Pharma
Publication of IL87894A0 publication Critical patent/IL87894A0/xx
Publication of IL87894A publication Critical patent/IL87894A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
IL8789488A 1987-10-02 1988-09-30 Esters of 71-carboxylic acid adendrostane, their preparation and pharmaceutical preparations containing them IL87894A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8713658A FR2621316B1 (fr) 1987-10-02 1987-10-02 Nouveaux esters d'acide androstane 17-carboxylique, procede pour leur preparation, et medicament les contenant

Publications (2)

Publication Number Publication Date
IL87894A0 IL87894A0 (en) 1989-03-31
IL87894A true IL87894A (en) 1994-02-27

Family

ID=9355472

Family Applications (1)

Application Number Title Priority Date Filing Date
IL8789488A IL87894A (en) 1987-10-02 1988-09-30 Esters of 71-carboxylic acid adendrostane, their preparation and pharmaceutical preparations containing them

Country Status (22)

Country Link
US (1) US4885280A (no)
EP (1) EP0310519B1 (no)
JP (1) JP2783560B2 (no)
KR (1) KR970002642B1 (no)
AT (1) ATE79630T1 (no)
AU (1) AU607100B2 (no)
CA (1) CA1306248C (no)
DE (1) DE3873870T2 (no)
DK (1) DK165595C (no)
EG (1) EG19114A (no)
ES (1) ES2052761T3 (no)
FI (1) FI89055C (no)
FR (1) FR2621316B1 (no)
GR (1) GR3005968T3 (no)
HK (1) HK60297A (no)
IE (1) IE61941B1 (no)
IL (1) IL87894A (no)
MY (1) MY103635A (no)
NO (1) NO173011C (no)
NZ (1) NZ226433A (no)
PT (1) PT88648B (no)
ZA (1) ZA887396B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5124154A (en) * 1990-06-12 1992-06-23 Insite Vision Incorporated Aminosteroids for ophthalmic use
US5256408A (en) * 1990-06-12 1993-10-26 Insite Vision Incorporated Aminosteroids for ophthalmic use
US5252319A (en) * 1990-06-12 1993-10-12 Insite Vision Incorporated Aminosteroids for ophthalmic use
US5209926A (en) * 1990-06-12 1993-05-11 Insite Vision Incorporated Aminosteroids for ophthalmic use
WO1993005790A1 (en) * 1991-09-27 1993-04-01 Procter & Gamble Pharmaceuticals, Inc. Use of 14-aminosteroids for the manufacture of a medicament to slow the rate of progression of myocardial structural damages characteristic of congestive heart failure
SK158394A3 (en) * 1992-06-26 1995-05-10 Pfizer Steroidal glycosides
PL313621A1 (en) * 1993-09-24 1996-07-08 Procter & Gamble Novel 14-aminosteroid compounds containing desoxy oxygen-substituted sugar
JPH09502982A (ja) * 1993-09-24 1997-03-25 ザ、プロクター、エンド、ギャンブル、カンパニー 新規なオリゴ糖含有14‐アミノステロイド化合物および新規なジアステレオ選択的アミノステロイド法の化学
US5922703A (en) * 1993-09-24 1999-07-13 The Procter & Gamble Company Urethane-containing aminosteroid compounds
AU700131B2 (en) * 1993-09-24 1998-12-24 Procter & Gamble Company, The Novel deoxy and oxygen-substituted sugar-containing 14-aminosteroid compounds
CZ413298A3 (cs) * 1996-06-17 1999-09-15 The Procter & Gamble Company 14-Aminosteroidní sloučeniny, obsahující deoxycukr a O-substituovaný cukru, pro použití jako antiarytmika
ATE473759T1 (de) 1998-05-22 2010-07-15 Univ Leland Stanford Junior Bifunktionelle moleküle sowie darauf basierende therapien.
CN103259027A (zh) 2005-04-28 2013-08-21 普罗透斯数字保健公司 药物信息系统
JP2009508494A (ja) 2005-09-16 2009-03-05 ラプトール ファーマシューティカル インコーポレイテッド Crを含むタンパク質に対して特異的な受容体−結合タンパク質(rap)変異体を含む組成物およびその使用
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
TWI556839B (zh) 2009-05-06 2016-11-11 研究室護膚股份有限公司 包含活性劑-磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法
GB201112402D0 (en) 2011-07-19 2011-08-31 British American Tobacco Co Cellulose acetate compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3449381A (en) * 1962-06-12 1969-06-10 Syntex Corp 19-oxo- and 19-lower alkyl-19-oxoandrostane derivatives
US3634409A (en) * 1966-04-26 1972-01-11 Syntex Corp 3beta-tetrahydrofuran-2'-yloxy-delta**4-steroids of the androstane and estrane series
FR2464270A1 (fr) * 1979-08-31 1981-03-06 Nativelle Sa Ets Nouveaux derives d'amino-14 steroides, et procede pour leur preparation
NZ205293A (en) * 1982-08-20 1986-12-05 Nativelle Sa Ets 14-aminosteroids and pharmaceutical compositions
ES8404694A1 (es) * 1982-08-20 1984-05-01 Nativelle Sa Ets Procedimiento de preparacion de nuevos derivos de amino-14 esteroides

Also Published As

Publication number Publication date
DK165595B (da) 1992-12-21
US4885280A (en) 1989-12-05
HK60297A (en) 1997-05-16
FI884511A (fi) 1989-04-03
DE3873870D1 (de) 1992-09-24
KR890006667A (ko) 1989-06-15
EP0310519B1 (fr) 1992-08-19
NO884344D0 (no) 1988-09-30
FI89055B (fi) 1993-04-30
GR3005968T3 (no) 1993-06-07
NO173011C (no) 1993-10-13
ATE79630T1 (de) 1992-09-15
AU2293588A (en) 1989-04-06
FI884511A0 (fi) 1988-09-30
JP2783560B2 (ja) 1998-08-06
ZA887396B (en) 1991-11-27
EG19114A (fr) 1994-07-30
ES2052761T3 (es) 1994-07-16
FR2621316A1 (fr) 1989-04-07
EP0310519A1 (fr) 1989-04-05
NO884344L (no) 1989-04-03
IE61941B1 (en) 1994-11-30
PT88648A (pt) 1988-10-01
IL87894A0 (en) 1989-03-31
DK165595C (da) 1993-05-03
NO173011B (no) 1993-07-05
NZ226433A (en) 1991-06-25
IE882991L (en) 1989-04-02
FR2621316B1 (fr) 1991-06-21
PT88648B (pt) 1992-12-31
CA1306248C (en) 1992-08-11
DK549388D0 (da) 1988-09-30
KR970002642B1 (ko) 1997-03-07
FI89055C (fi) 1993-08-10
JPH01156995A (ja) 1989-06-20
DK549388A (da) 1989-04-03
MY103635A (en) 1993-08-28
DE3873870T2 (de) 1993-02-18
AU607100B2 (en) 1991-02-21

Similar Documents

Publication Publication Date Title
IL87894A (en) Esters of 71-carboxylic acid adendrostane, their preparation and pharmaceutical preparations containing them
GB1599863A (en) Pharmaceutical compositions for use in the inhibition of the biosynthesis of mevalonic acid
EP0124068A1 (en) New derivatives of biliary acids, process for the production thereof and pharmaceutical compositions containing the same
KR20010052850A (ko) 테스토스테론 유도체
US3318927A (en) Alkylated estradiol
US3056727A (en) Cyclohexylcarbonates of steroids
US4332797A (en) Chlorambucil derivatives
GB1589787A (en) Pro-drugs for certain steroids
US3696091A (en) Novel cardiac-active principles of the cardenolide glycoside class
JPS5826899A (ja) ステロイド、その製造方法及び薬物としてのその用法
Zorbach et al. Strophanthidin Cardenolides Containing Hexoses of the Mannose Series1a
US3514514A (en) 17alpha-ethinyl-18-methyl-19-nortestosterone esters
DE1793618C3 (de) 07.03.63 USA 263441 Verfahren zur Herstellung von 3-Hydroxy-1,5-bisdehydrosteroiden der Androstanreihe
IL28867A (en) 1-adamantyl and 1-adamantylmethyl carbonates of testosterone and derivatives thereof
AU1713101A (en) Beta-d-5-thioxylose derivatives, preparation method and therapeutic use
CA1146533A (en) 11-methylene steroids, process for their manufacture and pharmaceutical preparations containing them
USRE28690E (en) 17α-Ethinyl-18-methyl-19-nortestosterone esters
US3483235A (en) New oestratrienes and process for their manufacture
US3511859A (en) 2,3-diazido/diamino-5alpha-androstan-17-ones and derivatives thereof
JPS5888400A (ja) 新規コレスタン誘導体
US3558607A (en) 1,3,5(10)-estratriene diesters
US3449321A (en) Estrogen water-soluble 16alpha-yl-glucopyranosiduronic compounds and preparation thereof
DE69102082T2 (de) Ungesättigte Gallsäurederivate, Verfahren zu ihrer Herstellung und pharmazeutische Präparate diese enthaltend.
US3478068A (en) 4alpha,10alpha;2beta,1' - bicyclo - 5beta - methyl - 19 - nor-steroids and their preparation
JPS6228157B2 (no)

Legal Events

Date Code Title Description
KB Patent renewed
RH Patent void
RH1 Patent not in force