IL87780A - 3-substituted 4-alkyl-4,5-dihydro-5-oxo-imidazo(1,5-a)thieno(2,3-d)-and(3,2-e)pyrimidine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

3-substituted 4-alkyl-4,5-dihydro-5-oxo-imidazo(1,5-a)thieno(2,3-d)-and(3,2-e)pyrimidine derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL87780A
IL87780A IL87780A IL8778088A IL87780A IL 87780 A IL87780 A IL 87780A IL 87780 A IL87780 A IL 87780A IL 8778088 A IL8778088 A IL 8778088A IL 87780 A IL87780 A IL 87780A
Authority
IL
Israel
Prior art keywords
alkyl
thieno
imidazo
dihydro
oxo
Prior art date
Application number
IL87780A
Other languages
English (en)
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL87780A publication Critical patent/IL87780A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IL87780A 1987-10-06 1988-09-16 3-substituted 4-alkyl-4,5-dihydro-5-oxo-imidazo(1,5-a)thieno(2,3-d)-and(3,2-e)pyrimidine derivatives,their preparation and pharmaceutical compositions containing them IL87780A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK522187A DK522187D0 (da) 1987-10-06 1987-10-06 Imidozothienopyrimidiner, deres fremstilling og anvendelse

Publications (1)

Publication Number Publication Date
IL87780A true IL87780A (en) 1992-02-16

Family

ID=8140567

Family Applications (1)

Application Number Title Priority Date Filing Date
IL87780A IL87780A (en) 1987-10-06 1988-09-16 3-substituted 4-alkyl-4,5-dihydro-5-oxo-imidazo(1,5-a)thieno(2,3-d)-and(3,2-e)pyrimidine derivatives,their preparation and pharmaceutical compositions containing them

Country Status (18)

Country Link
US (1) US4866065A (no)
EP (1) EP0311321B1 (no)
JP (1) JP2662426B2 (no)
KR (1) KR0130978B1 (no)
AT (1) ATE100107T1 (no)
AU (1) AU611718B2 (no)
CA (1) CA1323365C (no)
DE (1) DE3887064T2 (no)
DK (1) DK522187D0 (no)
ES (1) ES2061675T3 (no)
FI (1) FI91759C (no)
IE (1) IE64931B1 (no)
IL (1) IL87780A (no)
NO (1) NO168646C (no)
NZ (1) NZ226461A (no)
PH (1) PH25297A (no)
PT (1) PT88673B (no)
ZA (1) ZA887313B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5185446A (en) * 1990-09-04 1993-02-09 Neurogen Corporation Certain cycloalkyl imidazopyrimidines; a new class of gaba brainreceptor ligands
FR2872165B1 (fr) * 2004-06-24 2006-09-22 Sod Conseils Rech Applic Nouveaux derives de pyrimido-benzimidazole
JP2009528389A (ja) * 2006-03-02 2009-08-06 シーブイ・セラピューティクス・インコーポレイテッド Ａ２ａアデノシン受容体拮抗剤

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2411274A1 (de) * 1974-03-06 1975-09-18 Schering Ag Neue 2-nitrothieno eckige klammer auf 2,3-d eckige klammer zu pyrimidinon-derivate und verfahren zu ihrer herstellung
CA1142924A (en) * 1980-06-27 1983-03-15 Hoffmann-La Roche Limited Pyrimidine derivatives
GB8432073D0 (en) * 1984-12-19 1985-01-30 Roussel Lab Ltd Chemical compounds
AU587802B2 (en) * 1985-03-08 1989-08-31 Ferrosan A/S Novel oxadiazolyl imidazobenzodiazepine derivatives and methods of preparing such compounds
US4771051A (en) * 1985-05-17 1988-09-13 A/S Ferrosan 3-substituted-4,5-dihydro-5-oxo imidazoquinazolines, their preparation, and their use in treating benzodiazepin receptor-related ailments
US4622321A (en) * 1985-05-17 1986-11-11 As Ferrosan Oxadiazolylimidazobenzodiazepine, compositions, and method
EP0274009B1 (en) * 1985-10-17 1992-09-09 Novo Nordisk A/S Oxadiazolylacetonitriles, their preparation and use

Also Published As

Publication number Publication date
JP2662426B2 (ja) 1997-10-15
NZ226461A (en) 1990-05-28
IE64931B1 (en) 1995-09-20
US4866065A (en) 1989-09-12
FI91759C (fi) 1994-08-10
ES2061675T3 (es) 1994-12-16
ATE100107T1 (de) 1994-01-15
DE3887064T2 (de) 1994-05-05
EP0311321B1 (en) 1994-01-12
FI884595A0 (fi) 1988-10-06
IE882794L (en) 1989-04-06
FI884595A (fi) 1989-04-07
EP0311321A3 (en) 1990-08-01
KR890006653A (ko) 1989-06-15
PT88673B (pt) 1992-12-31
NO168646C (no) 1992-03-18
AU2334188A (en) 1989-04-06
KR0130978B1 (ko) 1998-04-16
AU611718B2 (en) 1991-06-20
JPH01121291A (ja) 1989-05-12
EP0311321A2 (en) 1989-04-12
NO168646B (no) 1991-12-09
DE3887064D1 (de) 1994-02-24
ZA887313B (en) 1989-06-28
PH25297A (en) 1991-04-30
FI91759B (fi) 1994-04-29
CA1323365C (en) 1993-10-19
DK522187D0 (da) 1987-10-06
NO884431D0 (no) 1988-10-05
NO884431L (no) 1989-04-07

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Legal Events

Date Code Title Description
RH Patent void