IL86821A - Process for dehydrogenation of steroid derivatives and intermediates therefor - Google Patents
Process for dehydrogenation of steroid derivatives and intermediates thereforInfo
- Publication number
- IL86821A IL86821A IL86821A IL8682188A IL86821A IL 86821 A IL86821 A IL 86821A IL 86821 A IL86821 A IL 86821A IL 8682188 A IL8682188 A IL 8682188A IL 86821 A IL86821 A IL 86821A
- Authority
- IL
- Israel
- Prior art keywords
- chem
- dehydrogenation
- steroid derivatives
- intermediates therefor
- straight
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
- C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
- C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Catalysts (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6757287A | 1987-06-29 | 1987-06-29 | |
US6756887A | 1987-06-29 | 1987-06-29 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL86821A0 IL86821A0 (en) | 1988-11-30 |
IL86821A true IL86821A (en) | 1993-05-13 |
Family
ID=26748021
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL86821A IL86821A (en) | 1987-06-29 | 1988-06-21 | Process for dehydrogenation of steroid derivatives and intermediates therefor |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0298652B1 (de) |
JP (1) | JPH0725791B2 (de) |
KR (1) | KR960015038B1 (de) |
AT (1) | ATE117317T1 (de) |
AU (1) | AU608860B2 (de) |
CA (1) | CA1331601C (de) |
CY (1) | CY1871A (de) |
DE (1) | DE3852790T2 (de) |
DK (1) | DK172531B1 (de) |
ES (1) | ES2066786T3 (de) |
GR (1) | GR3015690T3 (de) |
HK (1) | HK116695A (de) |
IE (1) | IE64996B1 (de) |
IL (1) | IL86821A (de) |
NZ (1) | NZ225100A (de) |
PT (1) | PT87777B (de) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5049562A (en) * | 1984-02-27 | 1991-09-17 | Merck & Co., Inc. | 17β-acyl-4-aza-5α-androst-1-ene-3-ones as 5α-reductase inhibitors |
US5084574A (en) * | 1988-04-18 | 1992-01-28 | Merck & Co., Inc. | Dehydrogenation process |
US5237061A (en) * | 1988-10-31 | 1993-08-17 | Merck & Co., Inc. | Methods of synthesizing benign prostatic hypertropic agents and their intermediates |
US5021575A (en) * | 1989-11-13 | 1991-06-04 | Merck & Co., Inc. | Method for introducing a 1,2 double bond into azasteroids |
GB9002922D0 (en) * | 1990-02-09 | 1990-04-04 | Erba Carlo Spa | 17 beta-substituted-4-aza-5 alpha-androstan-3-one derivatives and process for their preparation |
US5091534A (en) * | 1990-08-27 | 1992-02-25 | Merck & Co., Inc. | Trialkylsilyl trifluoromethanesulfonate mediated α-methylenic carbon functionalization of 4-AZA-5α-androstan-3-one steroids |
US5187278A (en) * | 1990-08-27 | 1993-02-16 | Merck & Co., Inc. | Trialkylsilyl trifluoromethanesulfonate mediated α-methylenic carbon functionalization of 4-aza-5α-androstan-3-one steroids |
US5120847A (en) * | 1990-08-27 | 1992-06-09 | Merck & Co., Inc. | Process for iodinating or brominating the α-methylenic carbon of a secondary amide |
WO1993023050A1 (en) * | 1992-05-20 | 1993-11-25 | Merck & Co., Inc. | NEW DELTA-17 AND DELTA-20 OLEFINIC AND SATURATED 17β-SUBSTITUTED-4-AZA-5α-ANDROSTAN-3-ONES AS 5α-REDUCTASE INHIBITORS |
KR950701527A (ko) * | 1992-05-21 | 1995-04-28 | 라브리 페르낭 | 테스토스테론 5α 환원효소 활성 저해제(INHIBITORS OF TESTOSTERONE 5α-REDUCTASE ACTIVITY) |
US5468860A (en) * | 1992-11-19 | 1995-11-21 | Merck & Co., Inc. | New finasteride processes |
TW369521B (en) * | 1993-09-17 | 1999-09-11 | Smithkline Beecham Corp | Androstenone derivative |
US5541322A (en) * | 1994-10-14 | 1996-07-30 | Glaxo Wellcome Inc. | Synthesis of 6-azaandrostenones |
WO1997015564A1 (en) * | 1995-10-26 | 1997-05-01 | Merck & Co., Inc. | 4-oxa and 4-thia steroids |
CZ2003679A3 (cs) * | 2000-09-07 | 2004-02-18 | Dr. Reddy´S Laboratories Ltd. | Nová polymorfní forma 17beta-(N-terc-butylkarbamoyl)-4-aza-5alfa-androst-1-en-3-on a způsob její přípravy |
CN1468254A (zh) | 2000-09-07 | 2004-01-14 | 雷迪实验室有限公司 | 17-β-(N-叔丁基氨基甲酰基)-4-氮杂-5-α-雄甾-1-烯-3-酮的新颖多晶型物及其制备方法 |
EP1322663A1 (de) * | 2000-09-07 | 2003-07-02 | Dr. Reddy's Laboratories Ltd. | Neue polymorphe form von 17-beta-(n-ter.butyl carbamoyl)-4-aza-5- g(a)-androst-1-en-3-one und ein verfahren zur ihrer herstellung |
US6645974B2 (en) | 2001-07-31 | 2003-11-11 | Merck & Co., Inc. | Androgen receptor modulators and methods for use thereof |
ES2185503B1 (es) * | 2001-09-29 | 2004-08-01 | Ragactives, S.L. | Procedimiento para la obtencion de 17beta-(sustituido)-3-oxoalfa1,2-4-azaesteroides e intermedios. |
HU227117B1 (en) | 2002-05-10 | 2010-07-28 | Richter Gedeon Nyrt | Process for dehydrogenation of aza-androstane compounds |
CA2497611A1 (en) | 2002-07-16 | 2004-01-22 | Siegfried Generics International Ag | Method for introducing a 1,2 double bond into 3-oxo-4-azasteroid compounds |
ES2206065B1 (es) | 2002-10-31 | 2005-08-16 | Ragactives, S.L. | Procedimiento para la obtencion de la forma polimorfica i de finasterida. |
KR100508019B1 (ko) | 2003-07-19 | 2005-08-17 | 한미약품 주식회사 | 고순도 1-안드로스텐 유도체의 제조 방법 |
CN1826314A (zh) * | 2003-07-21 | 2006-08-30 | 西格弗里德杰耐克斯国际两合公司 | α,β-不饱和酰胺化合物的制备方法 |
EP2070943A1 (de) * | 2007-12-14 | 2009-06-17 | Crystal Pharma, S.A. | Verfahren zur Herstellung von 6-Alkylidenandrost-1,4-dien-3-onen |
DE102010024714C5 (de) | 2010-06-23 | 2018-10-18 | Bwg Bergwerk- Und Walzwerk-Maschinenbau Gmbh | Verfahren zum Streckbiegerichten von Metallbändern und Streckbiegerichtanlage |
KR102234106B1 (ko) * | 2019-07-16 | 2021-04-01 | 한국에너지기술연구원 | NOx 및 SOx 동시 제거를 위한 흡수제, 조성물 및 방법 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS54109958A (en) * | 1978-02-16 | 1979-08-29 | Patpharma Ets | Steroid compound and its manufacture |
AU527030B2 (en) * | 1978-04-13 | 1983-02-10 | Merck & Co., Inc. | 4-aza-17-substituted-5a-androstan-3-ones |
ZA802452B (en) * | 1979-05-02 | 1981-04-29 | Richardson Merrell Inc | Novel steroid 5 alpha-reductase inhibitors |
NZ211145A (en) * | 1984-02-27 | 1988-10-28 | Merck & Co Inc | 4-aza-5-alpha-androst-1-en-3-ones and pharmaceutical compositions |
-
1988
- 1988-06-20 NZ NZ225100A patent/NZ225100A/xx unknown
- 1988-06-21 IL IL86821A patent/IL86821A/xx not_active IP Right Cessation
- 1988-06-21 PT PT87777A patent/PT87777B/pt not_active IP Right Cessation
- 1988-06-23 CA CA000570228A patent/CA1331601C/en not_active Expired - Lifetime
- 1988-06-27 DE DE3852790T patent/DE3852790T2/de not_active Expired - Lifetime
- 1988-06-27 AU AU18457/88A patent/AU608860B2/en not_active Expired
- 1988-06-27 AT AT88305926T patent/ATE117317T1/de not_active IP Right Cessation
- 1988-06-27 EP EP88305926A patent/EP0298652B1/de not_active Expired - Lifetime
- 1988-06-27 ES ES88305926T patent/ES2066786T3/es not_active Expired - Lifetime
- 1988-06-28 DK DK198803550A patent/DK172531B1/da not_active IP Right Cessation
- 1988-06-28 IE IE195888A patent/IE64996B1/en not_active IP Right Cessation
- 1988-06-28 KR KR1019880007814A patent/KR960015038B1/ko not_active IP Right Cessation
- 1988-06-29 JP JP63159579A patent/JPH0725791B2/ja not_active Expired - Fee Related
-
1995
- 1995-04-04 GR GR950400837T patent/GR3015690T3/el unknown
- 1995-07-13 HK HK116695A patent/HK116695A/xx not_active IP Right Cessation
-
1996
- 1996-04-05 CY CY187196A patent/CY1871A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
AU1845788A (en) | 1989-01-05 |
IE881958L (en) | 1988-12-29 |
CY1871A (en) | 1996-04-05 |
ATE117317T1 (de) | 1995-02-15 |
AU608860B2 (en) | 1991-04-18 |
KR960015038B1 (ko) | 1996-10-24 |
EP0298652A3 (en) | 1990-03-07 |
KR890000512A (ko) | 1989-03-15 |
NZ225100A (en) | 1991-09-25 |
DE3852790D1 (de) | 1995-03-02 |
JPH0725791B2 (ja) | 1995-03-22 |
IE64996B1 (en) | 1995-10-04 |
JPS6479198A (en) | 1989-03-24 |
EP0298652A2 (de) | 1989-01-11 |
CA1331601C (en) | 1994-08-23 |
ES2066786T3 (es) | 1995-03-16 |
DE3852790T2 (de) | 1995-08-17 |
PT87777B (pt) | 1992-10-30 |
PT87777A (pt) | 1989-05-31 |
DK355088D0 (da) | 1988-06-28 |
HK116695A (en) | 1995-07-21 |
DK355088A (da) | 1989-02-24 |
GR3015690T3 (en) | 1995-07-31 |
IL86821A0 (en) | 1988-11-30 |
EP0298652B1 (de) | 1995-01-18 |
DK172531B1 (da) | 1999-06-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
KB | Patent renewed | ||
EXP | Patent expired |