IL83079A - Nitrilotriacetic acid derivatives,metal chelate resins prepared therefrom and their use in chromatography - Google Patents

Nitrilotriacetic acid derivatives,metal chelate resins prepared therefrom and their use in chromatography

Info

Publication number
IL83079A
IL83079A IL83079A IL8307987A IL83079A IL 83079 A IL83079 A IL 83079A IL 83079 A IL83079 A IL 83079A IL 8307987 A IL8307987 A IL 8307987A IL 83079 A IL83079 A IL 83079A
Authority
IL
Israel
Prior art keywords
metal chelate
chromatography
nitrilotriacetic acid
acid derivatives
prepared therefrom
Prior art date
Application number
IL83079A
Other languages
English (en)
Other versions
IL83079A0 (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4241469&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL83079(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to IL9653587A priority Critical patent/IL96535A/xx
Publication of IL83079A0 publication Critical patent/IL83079A0/xx
Priority to IL96535A priority patent/IL96535A0/xx
Publication of IL83079A publication Critical patent/IL83079A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B01D15/3828—Ligand exchange chromatography, e.g. complexation, chelation or metal interaction chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds
    • B01J20/3265—Non-macromolecular compounds with an organic functional group containing a metal, e.g. a metal affinity ligand

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Treatment Of Water By Ion Exchange (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Manufacture And Refinement Of Metals (AREA)
  • Polymerisation Methods In General (AREA)
IL83079A 1986-07-10 1987-07-03 Nitrilotriacetic acid derivatives,metal chelate resins prepared therefrom and their use in chromatography IL83079A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IL9653587A IL96535A (en) 1986-07-10 1987-07-03 Nitrilotriacetic acid derivatives and their manufacture
IL96535A IL96535A0 (en) 1986-07-10 1990-12-04 Nitrilotriacetic acid derivatives and their manufacture

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH278286 1986-07-10

Publications (2)

Publication Number Publication Date
IL83079A0 IL83079A0 (en) 1987-12-31
IL83079A true IL83079A (en) 1991-11-21

Family

ID=4241469

Family Applications (1)

Application Number Title Priority Date Filing Date
IL83079A IL83079A (en) 1986-07-10 1987-07-03 Nitrilotriacetic acid derivatives,metal chelate resins prepared therefrom and their use in chromatography

Country Status (13)

Country Link
US (1) US4877830A (da)
EP (1) EP0253303B1 (da)
JP (2) JPH0822382B2 (da)
AT (1) ATE76866T1 (da)
AU (1) AU596674B2 (da)
CA (1) CA1304886C (da)
DE (1) DE3779501D1 (da)
DK (2) DK172602B1 (da)
IE (1) IE60468B1 (da)
IL (1) IL83079A (da)
NZ (1) NZ220948A (da)
PH (1) PH23746A (da)
ZA (1) ZA874860B (da)

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CA1304886C (en) * 1986-07-10 1992-07-07 Heinz Dobeli Metal chelate resins
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CA1340522C (en) * 1987-03-10 1999-05-04 Heinz Dobeli Fusion proteins containing neighbouring histidines for improved purification
US5225534A (en) * 1987-09-08 1993-07-06 Hoffmann-La Roche Inc. Recombinant malarial polypeptides
EP0309746A1 (de) * 1987-09-08 1989-04-05 F. Hoffmann-La Roche Ag Antimalaria-Vakzine
US4952321A (en) * 1988-10-07 1990-08-28 Brigham Young University Process of removing and concentrating desired ions from solutions
US5169936A (en) * 1989-04-14 1992-12-08 Biogen, Inc. Protein purification on immobilized metal affinity resins effected by elution using a weak ligand
DE59010560D1 (de) * 1989-08-19 1996-12-12 Qiagen Gmbh Verfahren und vorrichtung zur trennung und detektion von komponenten eines stoffgemisches durch temperaturgradienten-gelelektrophorese
US5266686A (en) * 1992-09-25 1993-11-30 Pierce Chemical Company Method for isolation and purification of enzyme-antibody conjugates
CA2125467C (en) * 1993-07-06 2001-02-06 Heinz Dobeli Process for producing hydrophobic polypeptides, proteins or peptides
SE9303822D0 (sv) * 1993-11-18 1993-11-18 Kabi Pharmacia Ab Method for purification
DE4433980C2 (de) * 1994-09-23 1996-08-22 Boehringer Ingelheim Int Verfahren und Biosensorhit zur Untersuchung der Wechselwirkung von Biomolekülen mittels Oberflächen-Plasma-Resonanz
US5620850A (en) 1994-09-26 1997-04-15 President And Fellows Of Harvard College Molecular recognition at surfaces derivatized with self-assembled monolayers
US6472148B1 (en) 1994-09-26 2002-10-29 President And Fellows Of Harvard College Molecular recognition at surfaces derivatized with self-assembled monolayers
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DE19531173A1 (de) * 1995-08-24 1997-02-27 Boehringer Mannheim Gmbh Verfahren zum Stabilisieren des Gehalts glykierten Proteins einer Probe auf einem Matrixmaterial
DE69730551T2 (de) 1996-04-15 2005-09-01 Givaudan S.A. Hydroxyperoxide Lyasen
US5858724A (en) * 1996-07-16 1999-01-12 Pel-Freez Recombinant rabbit tissue factor
US5962641A (en) * 1996-08-16 1999-10-05 Clontech Laboratories, Inc. Method for purification of recombinant proteins
US7014992B1 (en) 1996-11-05 2006-03-21 Clinical Micro Sensors, Inc. Conductive oligomers attached to electrodes and nucleoside analogs
DE19645729C1 (de) * 1996-11-06 1998-06-04 Brahms Diagnostica Gmbh Rezeptorbindungsassay, für den Rezeptorbindungsassay geeigneter rekombinanter Fusionsrezeptor, Vektor zu dessen Herstellung sowie Reagenziensatz für die Durchführung des Rezeptorbindungsassays
WO1998058952A1 (en) * 1997-06-24 1998-12-30 Proteus Molecular Design Limited Angiotensin derivatives
US6068993A (en) * 1997-07-02 2000-05-30 Biobras Sa Vector for expression of heterologous protein and methods for extracting recombinant protein and for purifying isolated recombinant insulin
US7087148B1 (en) 1998-06-23 2006-08-08 Clinical Micro Sensors, Inc. Binding acceleration techniques for the detection of analytes
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ES2248936T3 (es) 1999-03-04 2006-03-16 F. KURT RETSCH GMBH & CO. KG Procedimiento y dispositivo para descomponer material biologico.
US6479300B1 (en) 1999-03-15 2002-11-12 Millipore Corporation Metal loaded ligand bound membranes for metal ion affinity chromatography
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US7312087B2 (en) * 2000-01-11 2007-12-25 Clinical Micro Sensors, Inc. Devices and methods for biochip multiplexing
JP2001029783A (ja) * 1999-07-13 2001-02-06 Tran Quang Minh 親和性固定化金属樹脂
DK1069131T3 (da) 1999-07-15 2006-06-26 Qiagen Gmbh Fremgangsmåde til at skille partikelformige substrater fra en oplösning med et minimalt tab af partikler
US6379708B1 (en) * 1999-11-20 2002-04-30 Cytologic, Llc Method for enhancing immune responses in mammals
US6623655B1 (en) 2000-04-24 2003-09-23 Sigma-Aldrich Co. Metal chelating compositions
GB0028879D0 (en) * 2000-11-27 2001-01-10 Prometic Biosciences Ltd Adsorbents and their use
CA2467736A1 (en) * 2001-12-05 2003-06-19 Large Scale Biology Corporation Flexible method and apparatus for high throughput production and purification of multiple proteins
AU2003233498A1 (en) * 2002-06-10 2003-12-22 Phynexus, Inc. Biomolecule open channel solid phase extraction systems and methods
US7879621B2 (en) * 2003-05-08 2011-02-01 Phynexus, Inc. Open channel solid phase extraction systems and methods
US7122640B2 (en) * 2002-06-10 2006-10-17 Phynexus, Inc. Open channel solid phase extraction systems and methods
US20040224329A1 (en) * 2003-05-08 2004-11-11 Gjerde Douglas T. Three-dimensional solid phase extraction surfaces
US7151167B2 (en) * 2002-06-10 2006-12-19 Phynexus, Inc. Open channel solid phase extraction systems and methods
US8025873B2 (en) 2002-06-20 2011-09-27 Paladin Labs, Inc. Chimeric antigens for eliciting an immune response
US8029803B2 (en) 2002-06-20 2011-10-04 Paladin Labs, Inc. Chimeric antigens for eliciting an immune response
CA2498341A1 (en) * 2002-10-18 2004-04-29 Promega Corporation Composition for separating molecules
US7799526B2 (en) * 2002-11-21 2010-09-21 The University Of North Carolina At Chapel Hill Phosphoprotein detection reagent and methods of making and using the same
SE526214C2 (sv) * 2003-02-28 2005-07-26 Amersham Biosciences Ab Ett sätt att generera metallkelaterande affinitetsligander
SE0301011D0 (sv) * 2003-04-04 2003-04-04 Amersham Biosciences Ab Preparation of a metal chelating separation medium
US20040241721A1 (en) * 2003-05-08 2004-12-02 Gjerde Douglas T. Open channel solid phase extraction systems and methods
JP2007528870A (ja) * 2003-05-23 2007-10-18 アプラーゲン ゲゼルシャフト ミット ベシュレンクテル ハフツング ペプチドの合成
US8007805B2 (en) * 2003-08-08 2011-08-30 Paladin Labs, Inc. Chimeric antigens for breaking host tolerance to foreign antigens
US20050123932A1 (en) * 2003-12-09 2005-06-09 Mekbib Astatke Nucleic acid-chelating agent conjugates
US7276362B2 (en) * 2004-01-30 2007-10-02 Roche Diagnostics Operations, Inc. Recombinant histidine-tagged inosine monophosphate dehydrogenase polypeptides
DE102004038134B4 (de) 2004-08-05 2013-07-25 Johann Wolfgang Goethe-Universität Frankfurt am Main Multivalente Chelatoren zum Modifizieren und Organisieren von Zielmolekülen, Verfahren zu ihrer Herstellung sowie ihre Verwendung
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US20070196833A1 (en) * 2005-04-21 2007-08-23 Gjerde Douglas T Open channel solid phase extraction systems and methods
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US20070065514A1 (en) * 2005-09-22 2007-03-22 Howell Mark D Method for enhancing immune responses in mammals
AU2006301846A1 (en) * 2005-10-13 2007-04-19 Akshaya Bio Inc. Chimeric antigen containing hepatitis C virus polypeptide and FC fragment for eliciting an immune response
WO2007120999A2 (en) * 2006-03-06 2007-10-25 Bio-Rad Laboratories, Inc. Chelating monomers and polymers
GB0610479D0 (en) * 2006-05-26 2006-07-05 Ge Healthcare Bio Sciences Ab A method for generating metal chelating affinity ligands
WO2009008802A1 (en) * 2007-07-09 2009-01-15 Ge Healthcare Bio-Sciences Ab Method for preparation of a biomolecule adsorbent
US20090162845A1 (en) * 2007-12-20 2009-06-25 Elazar Rabbani Affinity tag nucleic acid and protein compositions, and processes for using same
KR20160110544A (ko) * 2008-06-04 2016-09-21 그리폴스 테라퓨틱스 인코포레이티드 플라스민의 제조를 위한 조성물, 방법 및 키트
EP2192410B1 (en) 2008-11-26 2012-07-11 Corning Incorporated Nanoparticulate affininty capture for label independent detections system
US9206410B2 (en) 2009-03-03 2015-12-08 Grifols Therapeutics Inc. Compositions, methods and kits for preparing plasminogen and plasmin prepared therefrom
JP2013507124A (ja) * 2009-10-09 2013-03-04 アナフォア インコーポレイテッド Ｉｌ−２３ｒを結合するポリペプチド
EP2362220A1 (en) 2010-02-25 2011-08-31 Corning Incorporated Affinity hydrogel and label independent detection methods thereof
HU230585B1 (hu) 2012-05-30 2017-01-30 Budapesti Műszaki és Gazdaságtudományi Egyetem Fehérjék megkötésére és elválasztására alkalmas lantanida fémionokkal komplexált hordozók
JP2014113108A (ja) * 2012-12-11 2014-06-26 Tokyo Medical Univ タンパク質の可溶化活性を有する多量体タンパク質およびその用途
JP7544704B2 (ja) 2018-11-28 2024-09-03 キューブ バイオテック ゲーエムベーハー 固相キレート材、その製造方法およびタンパク質の精製におけるその使用
CN109535274B (zh) * 2018-11-30 2021-02-19 淮阴工学院 一种蒲菜多糖脱蛋白脱色的方法
EP4288411A1 (en) 2021-02-02 2023-12-13 Cube Biotech GmbH Soluble chelator for targeting recombinant proteins
CN113150194A (zh) * 2021-02-24 2021-07-23 广东昊邦医药健康有限责任公司 金属螯合树脂及其制备方法、应用
CN117339580B (zh) * 2023-12-05 2024-04-02 凯莱英生命科学技术(天津)有限公司 螯合载体、其制备方法及应用

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AU426693B2 (en) * 1968-07-18 1972-07-31 Mobil Oil Corporation Fuel additive
US4530963A (en) * 1982-08-20 1985-07-23 Devoe-Holbein International, N.V. Insoluble chelating compositions
CA1304886C (en) * 1986-07-10 1992-07-07 Heinz Dobeli Metal chelate resins

Also Published As

Publication number Publication date
IE871842L (en) 1988-01-10
JPH0899944A (ja) 1996-04-16
CA1304886C (en) 1992-07-07
PH23746A (en) 1989-11-03
JPS6344947A (ja) 1988-02-25
DK172602B1 (da) 1999-02-22
US4877830A (en) 1989-10-31
ATE76866T1 (de) 1992-06-15
EP0253303B1 (de) 1992-06-03
IL83079A0 (en) 1987-12-31
NZ220948A (en) 1990-07-26
DK172891B1 (da) 1999-09-13
DK149397A (da) 1997-12-19
DE3779501D1 (de) 1992-07-09
JPH0822382B2 (ja) 1996-03-06
ZA874860B (en) 1988-01-11
EP0253303A3 (en) 1989-05-24
IE60468B1 (en) 1994-07-13
AU7524587A (en) 1988-01-14
DK285187A (da) 1988-01-11
JP2562571B2 (ja) 1996-12-11
DK285187D0 (da) 1987-06-03
AU596674B2 (en) 1990-05-10
EP0253303A2 (de) 1988-01-20

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