IL81610A - Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them - Google Patents

Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL81610A
IL81610A IL81610A IL8161087A IL81610A IL 81610 A IL81610 A IL 81610A IL 81610 A IL81610 A IL 81610A IL 8161087 A IL8161087 A IL 8161087A IL 81610 A IL81610 A IL 81610A
Authority
IL
Israel
Prior art keywords
radical
carbon atoms
preparation
compositions containing
tetrahydropyridin
Prior art date
Application number
IL81610A
Other languages
English (en)
Other versions
IL81610A0 (en
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT19565/86A external-priority patent/IT1191667B/it
Priority claimed from IT21157/86A external-priority patent/IT1196510B/it
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of IL81610A0 publication Critical patent/IL81610A0/xx
Publication of IL81610A publication Critical patent/IL81610A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL81610A 1986-02-27 1987-02-18 Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them IL81610A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT19565/86A IT1191667B (it) 1986-02-27 1986-02-27 Derivati della 1,2,5,6-tetraidropiridin-3-carbossaldeide ossima,loro procedimento di preparazione e loro applicazione come farmaci
IT21157/86A IT1196510B (it) 1986-07-17 1986-07-17 Derivati della 1,2-5,6-tetraidropiridin-3-carbossaldeide ossima,loro procedimento di preparazione e loro applicazione come farmaci

Publications (2)

Publication Number Publication Date
IL81610A0 IL81610A0 (en) 1987-09-16
IL81610A true IL81610A (en) 1990-12-23

Family

ID=26327212

Family Applications (1)

Application Number Title Priority Date Filing Date
IL81610A IL81610A (en) 1986-02-27 1987-02-18 Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them

Country Status (20)

Country Link
US (3) US5219872A (cs)
EP (1) EP0239445B1 (cs)
JP (1) JPH07599B2 (cs)
KR (1) KR950005197B1 (cs)
AT (1) ATE76066T1 (cs)
AU (1) AU588972B2 (cs)
BG (1) BG61120B2 (cs)
CA (1) CA1327803C (cs)
DE (1) DE3778951D1 (cs)
DK (1) DK167803B1 (cs)
ES (1) ES2032456T3 (cs)
FI (1) FI87199C (cs)
GR (1) GR3004845T3 (cs)
HK (1) HK29797A (cs)
HU (1) HU198018B (cs)
IE (1) IE59095B1 (cs)
IL (1) IL81610A (cs)
NO (1) NO172180C (cs)
NZ (1) NZ219416A (cs)
PT (1) PT84366B (cs)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4786648A (en) * 1986-12-08 1988-11-22 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
US4710508A (en) * 1986-12-08 1987-12-01 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
US4798841A (en) * 1987-03-31 1989-01-17 Warner-Lambert Company Tetrahydropyridine oxime cholinergic agents and method of treatment
IT1203971B (it) * 1987-04-24 1989-02-23 Roussel Maestretti Spa Derivati di 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro applicazione come medicamenti
IT1222526B (it) * 1987-08-21 1990-09-05 Roussel Maestretti Spa Derivati dell' ossima della 1,2,5,6-tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
IL88156A (en) * 1987-11-13 1997-02-18 Novo Nordisk As Azacyclic compounds their preparation and pharmaceutical compositions containing them
IT1233446B (it) * 1987-12-30 1992-04-01 Roussel Maestretti Spa Derivati della 3 piperidinocarbaldeide ossima, loro procedimento di preparazione e loro applicazione come farmaci
DK177889A (da) * 1988-04-15 1989-10-16 Beecham Group Plc Hidtil ukendte forbindelser
US5278170A (en) * 1989-04-13 1994-01-11 Beecham Group P.L.C. Azabicylo oxime compounds
DK0392803T3 (da) * 1989-04-13 2004-10-18 Beecham Group Plc Hidtil ukendte forbindelser
IT1240603B (it) * 1990-03-14 1993-12-17 Roussel Maestretti Spa Derivati della 1,2,5,6-tetraidropiridina 3- carbossaldeide ossima, loro procedimento di preparazione e loro impiego come sostanza medicinale
IT1241138B (it) * 1990-05-15 1993-12-29 Roussel Pharma Derivati dell'ossina della 1,2,5,6- tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
MX9100779A (es) * 1990-08-24 1992-04-01 Beecham Group Plc Compuestos azabiciclicos y procedimiento para su preparacion
GB9019095D0 (en) * 1990-09-01 1990-10-17 Beecham Group Plc Novel compounds
EP0552213A1 (en) * 1990-10-12 1993-07-28 Beecham Group Plc 1,2,5,6-tetrahydropyridine oxime derivatives
AU3142793A (en) * 1991-12-18 1993-07-19 Warner-Lambert Company Transdermal delivery of (E)-1,2,5,6-tetrahydro-1-methyl-3-pyridine-carboxaldehyde-O- methyloxine HCL and related compounds in the treatment of cognitive disorders and for analgesia
ZA937382B (en) * 1992-10-06 1994-04-29 Warner Lambert Co Novel composition for peroral therapy of cognitionimpairment and a process therefor
AU5297693A (en) * 1992-10-06 1994-04-26 Warner-Lambert Company Stabilized compositions containing 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxyaldehyde-o-meth yl-oxime
US5424301A (en) * 1993-02-01 1995-06-13 Warner-Lambert Company Starch stabilized o-substituted tetrahydropyridine oxime cholinergic agents
US5731314A (en) * 1995-01-06 1998-03-24 Bencherif; Merouane Pharamceutical compositions for prevention and treatment of tourette's syndrome
US5583140A (en) * 1995-05-17 1996-12-10 Bencherif; Merouane Pharmaceutical compositions for the treatment of central nervous system disorders
DE19707655A1 (de) * 1997-02-26 1998-08-27 Hoechst Ag Kombinationspräparat zur Anwendung bei Demenz
US6455648B1 (en) 1999-12-29 2002-09-24 Chevron Phillips Chemical Company Lp Olefin production
ATE445838T1 (de) 2001-07-25 2009-10-15 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
CA2789097C (en) 2005-04-28 2017-02-21 Proteus Digital Health, Inc. Pharma-informatics system
CA2663377A1 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
US9877500B2 (en) * 2007-03-14 2018-01-30 Concentrate Manufacturing Company Of Ireland Natural beverage products
PL2398500T3 (pl) 2009-02-20 2019-09-30 2-Bbb Medicines B.V. System dostarczania leków na bazie glutationu
BRPI1011188B1 (pt) 2009-05-06 2019-10-15 Laboratory Skin Care, Inc. Composições de liberação dérmica compreendendo complexos de partículas de agente ativo-fosfato de cálcio e métodos para usar as mesmas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CH704993A1 (fr) 2011-05-20 2012-11-30 Bacab S A Câble électrique.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3004979A (en) * 1961-10-17 Oximes of certain tetrahydropyridine
FR1258847A (fr) * 1960-02-12 1961-04-21 Ciba Geigy Procédé de préparation de nouveaux dérivés pyridiniques, entre autres de l'oxime de la l-méthyl-3 ou 4-acétyl-1, 2, 5, 6-tétrahydropyridine
US4710508A (en) * 1986-12-08 1987-12-01 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
US4786648A (en) * 1986-12-08 1988-11-22 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
IT1203971B (it) * 1987-04-24 1989-02-23 Roussel Maestretti Spa Derivati di 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro applicazione come medicamenti

Also Published As

Publication number Publication date
HK29797A (en) 1997-03-21
FI870842L (fi) 1987-08-28
NO172180B (no) 1993-03-08
EP0239445A2 (fr) 1987-09-30
HU198018B (en) 1989-07-28
DK98787D0 (da) 1987-02-26
NO870771L (no) 1987-08-28
NZ219416A (en) 1989-04-26
JPH07599B2 (ja) 1995-01-11
GR3004845T3 (cs) 1993-04-28
KR950005197B1 (ko) 1995-05-19
FI87199B (fi) 1992-08-31
IE870497L (en) 1987-08-27
NO172180C (no) 1993-06-16
IE59095B1 (en) 1994-01-12
KR870007890A (ko) 1987-09-22
PT84366B (pt) 1989-10-04
JPS62252767A (ja) 1987-11-04
EP0239445A3 (en) 1989-01-18
HUT44497A (en) 1988-03-28
FI87199C (fi) 1992-12-10
DE3778951D1 (de) 1992-06-17
DK98787A (da) 1987-08-28
ES2032456T3 (es) 1993-02-16
EP0239445B1 (fr) 1992-05-13
US5219872A (en) 1993-06-15
AU6927987A (en) 1987-09-03
IL81610A0 (en) 1987-09-16
ATE76066T1 (de) 1992-05-15
DK167803B1 (da) 1993-12-20
US5532375A (en) 1996-07-02
US5391754A (en) 1995-02-21
CA1327803C (en) 1994-03-15
BG61120B2 (bg) 1996-11-29
FI870842A0 (fi) 1987-02-26
NO870771D0 (no) 1987-02-25
PT84366A (en) 1987-03-01
AU588972B2 (en) 1989-09-28

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Legal Events

Date Code Title Description
KB Patent renewed
HCE Change of name and address of proprietor(s)
KB Patent renewed
HCA Change of name of proprietor(s) after amalgamation
MM9K Patent not in force due to non-payment of renewal fees