IL80670A - Bicyclic sulfonamide derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same - Google Patents

Bicyclic sulfonamide derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same

Info

Publication number
IL80670A
IL80670A IL80670A IL8067086A IL80670A IL 80670 A IL80670 A IL 80670A IL 80670 A IL80670 A IL 80670A IL 8067086 A IL8067086 A IL 8067086A IL 80670 A IL80670 A IL 80670A
Authority
IL
Israel
Prior art keywords
processes
preparation
same
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL80670A
Other languages
English (en)
Other versions
IL80670A0 (en
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of IL80670A0 publication Critical patent/IL80670A0/xx
Publication of IL80670A publication Critical patent/IL80670A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/32—Sulfur atoms
    • C07D213/34—Sulfur atoms to which a second hetero atom is attached
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL80670A 1985-11-18 1986-11-17 Bicyclic sulfonamide derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same IL80670A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP25915485 1985-11-18
JP3013086 1986-02-13
JP11559986 1986-05-19
JP12901186 1986-06-03
JP16925786 1986-07-17

Publications (2)

Publication Number Publication Date
IL80670A0 IL80670A0 (en) 1987-02-27
IL80670A true IL80670A (en) 1991-06-10

Family

ID=27521199

Family Applications (1)

Application Number Title Priority Date Filing Date
IL80670A IL80670A (en) 1985-11-18 1986-11-17 Bicyclic sulfonamide derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same

Country Status (20)

Country Link
US (6) US4861913A (es)
EP (1) EP0226346B1 (es)
JP (1) JPS63139161A (es)
CN (1) CN1019194B (es)
AR (1) AR245102A1 (es)
AT (1) ATE66207T1 (es)
AU (1) AU595554B2 (es)
CA (1) CA1278577C (es)
DE (1) DE3680884D1 (es)
DK (1) DK169918B1 (es)
ES (1) ES2051693T3 (es)
FI (1) FI90064C (es)
GB (1) GB2184118B (es)
GR (1) GR3002489T3 (es)
HU (1) HU203078B (es)
IE (1) IE58988B1 (es)
IL (1) IL80670A (es)
NO (1) NO165442C (es)
NZ (1) NZ218115A (es)
PT (1) PT83744B (es)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1278577C (en) * 1985-11-18 1991-01-02 Tatsuo Tsuri Bicyclic sulfonamide derivatives
GB8708233D0 (en) * 1987-04-07 1987-05-13 Smith Kline French Lab Pharmaceutically active compounds
CA1294974C (en) * 1987-05-08 1992-01-28 Sanji Hagishita Bicyclic sulfonamide derivatives and process therefor
GB8717374D0 (en) * 1987-07-22 1987-08-26 Smith Kline French Lab Pharmaceutically active compounds
EP0516181A1 (en) * 1987-10-23 1992-12-02 Ono Pharmaceutical Co., Ltd. Novel sulfonamide derivatives
JP2565746B2 (ja) * 1987-10-23 1996-12-18 小野薬品工業株式会社 新規な炭素環系スルホンアミド誘導体
EP0312906A3 (en) * 1987-10-23 1990-09-05 Ono Pharmaceutical Co., Ltd. Novel sulfonamide derivatives
EP0516180A1 (en) * 1988-04-19 1992-12-02 Ono Pharmaceutical Co., Ltd. Novel sulfonamide derivatives
CA1332607C (en) * 1988-07-19 1994-10-18 Masayuki Narisada Alkenyltetrazole derivatives
US5241104A (en) * 1988-12-14 1993-08-31 Shionogi & Co., Ltd. Mono ester of dicarboxylic acid and process thereof
US5008409A (en) * 1988-12-14 1991-04-16 Shionogi & Co., Ltd. Process for preparing 1,4-bridged cyclohexane carboxylic acid derivatives
KR0138528B1 (en) * 1988-12-14 1998-05-01 Shionogi Seiyaku Kk Preparation of 2,3-trans-1,4-bridged cyclohexane sulfonamide derivatives
US5117039A (en) * 1988-12-14 1992-05-26 Shionogi & Co., Ltd. Monoesters of arylacetic acid and the process thereof
US5047574A (en) * 1988-12-14 1991-09-10 Shionogi & Co., Ltd. Certain optically active mono esters of dicarboxylic acids
JP2756689B2 (ja) * 1989-02-20 1998-05-25 塩野義製薬株式会社 置換ヘキセン酸誘導体
DK0557519T3 (da) * 1989-10-18 1997-06-23 Shionogi & Co Fremgangsmåde til fremstilling af sulfonamidderivater af norbornan
US5763647A (en) * 1990-03-30 1998-06-09 Shionogi & Co., Ltd. Preparation of optically active 1,4-bridged-cyclohexane carboxylic acid derivatives
JP2891740B2 (ja) * 1990-03-30 1999-05-17 塩野義製薬株式会社 光学活性ノルボルナン系アミン誘導体の製造方法
JP2984077B2 (ja) * 1990-04-19 1999-11-29 塩野義製薬株式会社 スルホニルアミノ置換ビシクロ環系ヒドロキサム酸誘導体
FR2665440B1 (fr) * 1990-07-31 1994-02-04 Lipha Nouveaux cycloalkylsulfonamides substitues, procedes de preparation et medicaments les contenant.
US5550248A (en) * 1990-11-29 1996-08-27 E.R. Squibb & Sons, Inc. Substituted stryl heterocyclic amido prostaglandin analogs
US5334369A (en) * 1991-06-11 1994-08-02 Medical University Of South Carolina Platelet receptor antagonists useful in detecting intravascular platelet aggregation
US5827868A (en) * 1991-10-07 1998-10-27 E. R. Squibb & Sons, Inc. Prostaglandin analogs
CA2113787A1 (en) * 1993-01-29 1994-07-30 Nobuyuki Hamanaka Carbocyclic sulfonamides
CA2225250C (en) * 1995-06-21 2005-03-22 Shionogi & Co., Ltd. Bicyclic amino derivatives and pgd2 antagonist containing the same
IL118727A (en) * 1995-06-29 2003-01-12 Lilly Co Eli (-)-2-spiro-5-hydantoinbicyclo [3.1.0] hexane-6-carboxylic acid, salts thereof and use thereof for the preparation of (+)-(2) aminobicyclo [3.1.0] hexane-2,6-dicarboxylic acid
WO1997017950A1 (en) * 1995-11-16 1997-05-22 Eli Lilly And Company Shoulder prosthesis
ZA969485B (en) * 1995-11-16 1998-05-12 Lilly Co Eli Excitatory amino acid receptor antagonists.
US6056974A (en) * 1996-04-26 2000-05-02 Shionogi & Co., Ltd. Rapid-release S1452 tablets
ATE295360T1 (de) * 1996-12-12 2005-05-15 Shionogi & Co Kondensierte heterocyclische benzolcarbonsäureamid-derivate und diese enthaltende pgd2 antagonisten
CZ297324B6 (cs) * 1996-12-13 2006-11-15 Shionogi & Co., Ltd. Benzothiofenkarboxamidové deriváty a antagonisty PGD2, které je obsahují
ZA984040B (en) 1997-05-15 1998-11-20 Ono Pharmaceutical Co Benzenesulfonamide compounds
WO1999015502A1 (fr) 1997-09-19 1999-04-01 Shionogi & Co., Ltd. Composes ayant un squelette [2.2.1]bicyclo
ES2244179T3 (es) * 1998-03-31 2005-12-01 SHIONOGI & CO., LTD. Proceso para la preparacion de derivados de acido 5-hidroxibenzo(b)tiofen-3-carboxilico.
PA8469401A1 (es) * 1998-04-10 2000-05-24 Pfizer Prod Inc Derivados biciclicos del acido hidroxamico
WO2000030683A1 (fr) * 1998-11-19 2000-06-02 Shionogi & C0., Ltd. Composes prophylactiques et/ou therapeutiques destines a des maladies du systeme nerveux central et possedant des composes antagonistes du recepteur de txa2 et/ou inhibiteurs de la txa2 synthase
JP2000351729A (ja) * 1999-06-08 2000-12-19 Shionogi & Co Ltd トロンボキサンａ２受容体拮抗剤の経皮吸収製剤
KR100733752B1 (ko) 1999-11-26 2007-06-29 시오노기세이야쿠가부시키가이샤 Ｎｐｙｙ５ 길항제
US7365196B2 (en) * 2000-03-20 2008-04-29 Merck Sharp & Dohme Ltd. Sulphonamido-substituted bridged bicycloalkyl derivatives
US6727277B1 (en) 2002-11-12 2004-04-27 Kansas State University Research Foundation Compounds affecting cholesterol absorption
JP5861884B2 (ja) * 2012-03-29 2016-02-16 荒川化学工業株式会社 エキソ型ノルボルネン化合物の製造方法
CN110563006A (zh) * 2019-09-25 2019-12-13 新乡市锦源化工有限公司 一种对位酯生产中亚硫酸氢钠处理方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2004327A1 (de) * 1969-02-14 1970-09-03 F. Hoffmann-La Roche & Co Ag, Basel (Schweiz) Bornanocarboxamide
US3988362A (en) * 1972-08-10 1976-10-26 Hoffmann-La Roche Inc. Intermediates for preparation of 2,2,3-endotrimethyl-7-anti-amino-norbornanes
EP0045118B1 (en) * 1979-01-05 1984-04-04 National Research Development Corporation Intermediates for the synthesis of bicyclo (2,2,1) heptanes and bicyclo (2,2,1) hept-2z-enes
DE3162659D1 (en) * 1980-07-22 1984-04-19 Ono Pharmaceutical Co 9,11-methano-13-aza-11a-carbathrombanoic acid analogues and pharmaceutical use thereof
JPS5813551A (ja) 1981-07-16 1983-01-26 Ono Pharmaceut Co Ltd １３−アザトロンボキサン類似化合物、その製造方法及びその化合物を有効成分として含有するトロンボキサン起因疾患治療剤
AU561739B2 (en) * 1981-12-23 1987-05-14 British Technology Group Limited Prostaglandins
US4456615A (en) * 1982-10-25 1984-06-26 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction
US4456616A (en) * 1982-12-27 1984-06-26 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction
US4647585A (en) * 1984-11-08 1987-03-03 E. R. Squibb & Sons, Inc. Bicycloheptane substituted ethers
US4663336A (en) * 1985-07-01 1987-05-05 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted diamide and its congener prostaglandin analogs useful in the treatment of thrombotic disease
US4654357A (en) * 1985-08-09 1987-03-31 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted sulfonamide prostaglandin analogs
CA1278577C (en) * 1985-11-18 1991-01-02 Tatsuo Tsuri Bicyclic sulfonamide derivatives
US4734424A (en) * 1986-09-24 1988-03-29 E. R. Squibb & Sons, Inc. Bicycloheptane substituted diamide and its congener prostaglandin analogs
CA1294974C (en) * 1987-05-08 1992-01-28 Sanji Hagishita Bicyclic sulfonamide derivatives and process therefor

Also Published As

Publication number Publication date
NZ218115A (en) 1990-02-26
AU6536086A (en) 1987-05-21
CA1278577C (en) 1991-01-02
NO864542D0 (no) 1986-11-14
NO864542L (no) 1987-05-19
JPS63139161A (ja) 1988-06-10
GR3002489T3 (en) 1992-12-30
ATE66207T1 (de) 1991-08-15
FI90064C (fi) 1993-12-27
US5043451A (en) 1991-08-27
CN1019194B (zh) 1992-11-25
IL80670A0 (en) 1987-02-27
DK549086A (da) 1987-05-19
IE863002L (en) 1987-05-18
FI864675A0 (fi) 1986-11-17
EP0226346B1 (en) 1991-08-14
CN86108584A (zh) 1987-07-29
US4861913A (en) 1989-08-29
AU595554B2 (en) 1990-04-05
US5043456A (en) 1991-08-27
AR245102A1 (es) 1993-12-30
EP0226346A1 (en) 1987-06-24
GB2184118A (en) 1987-06-17
GB8627561D0 (en) 1986-12-17
US4976891A (en) 1990-12-11
PT83744A (en) 1986-12-01
US5041635A (en) 1991-08-20
JPH0579060B2 (es) 1993-11-01
DK549086D0 (da) 1986-11-17
DK169918B1 (da) 1995-04-03
PT83744B (pt) 1988-08-17
NO165442C (no) 1991-02-13
IE58988B1 (en) 1993-12-15
NO165442B (no) 1990-11-05
HUT44765A (en) 1988-04-28
DE3680884D1 (de) 1991-09-19
FI864675A (fi) 1987-05-19
FI90064B (fi) 1993-09-15
US4960909A (en) 1990-10-02
HU203078B (en) 1991-05-28
GB2184118B (en) 1990-01-17
ES2051693T3 (es) 1994-07-01

Similar Documents

Publication Publication Date Title
IL80670A0 (en) Bicyclic sulfonamide derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL84522A0 (en) Imidazopyridine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL77762A (en) 11beta-phenyl gonane derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
HK18194A (en) Substituted benzamide derivatives,processes for the preparation thereof,and pharmaceutical compositions containing the same
IL75400A0 (en) Dialkoxypyridines,processes for the preparation thereof and pharmaceutical compositions containing the same
IL75120A0 (en) New pyrrolobenzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing them
IL81950A0 (en) 2-azolylmethyl-2-aryl-1,3-dioxolanes and the salts thereof processes for the preparation thereof and pharmaceutical compositions containing them
IL87809A0 (en) Imidazopyridine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL83760A0 (en) Cephem compounds,processes for the preparation thereof and pharmaceutical compositions containing the same
IL80160A (en) Beta-lactam derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL87731A0 (en) Cephem derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL80669A0 (en) Cephem compounds,processes for the preparation thereof and pharmaceutical compositions containing the same
ZA879166B (en) Pyrrolobenzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing them
ZA859729B (en) New imidazo derivatives,the preparation thereof and pharmaceutical compositions containing these compounds
AR243499A1 (es) Un procedimiento para la preparacion de derivados de sulfonanilida.
IL88903A0 (en) Indolylpiperidine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL78576A0 (en) 5-pyrimidinecarboxamide,processes for the preparation thereof and pharmaceutical compositions containing same
IL87563A0 (en) Isoxazole-beta-carboline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL84728A (en) Bicyclic v-triazine-4-one derivatives,their manufacture and pharmaceutical compositions containing them
GB2179347B (en) Methylenedioxyphenanthrene and -stilbene derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
IL81949A0 (en) 2-azolylmethyl-2-aryl-1,3-dioxolanes and the salts thereof,processes for their preparation and pharmaceutical compositions containing them
PT83231A (en) Process for the preparation of gem-dihalo-1,8-diamino-4-aza-octanes and of pharmaceutical compositions containing the same
IL83133A0 (en) Bicyclic thiaaza compounds,their manufacture and pharmaceutical compositions containing them
GB2184726B (en) Azoniaspironortropanol esters, processes for the preparation thereof and pharmaceutical compositions containing them
DE3665720D1 (en) Novel ll-methylene-oestr-15-enes, processes for their preparation, and pharmaceutical compositions

Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed