NO165442C - Analogifremgangsmaate for fremstilling av bicykliske sulfonamid-derivater. - Google Patents

Analogifremgangsmaate for fremstilling av bicykliske sulfonamid-derivater.

Info

Publication number
NO165442C
NO165442C NO864542A NO864542A NO165442C NO 165442 C NO165442 C NO 165442C NO 864542 A NO864542 A NO 864542A NO 864542 A NO864542 A NO 864542A NO 165442 C NO165442 C NO 165442C
Authority
NO
Norway
Prior art keywords
bicyclic
preparation
sulphonamide derivatives
analogy procedure
analogy
Prior art date
Application number
NO864542A
Other languages
English (en)
Other versions
NO864542L (no
NO864542D0 (no
NO165442B (no
Inventor
Masayuki Narisada
Mitsuaki Ohtani
Fumihiko Watanabe
Sanji Hagishita
Kaoru Seno
Susumu Kamata
Nobuhiro Haga
Tatsuo Tsuri
Tadahiko Tsushima
Kenji Kawada
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of NO864542D0 publication Critical patent/NO864542D0/no
Publication of NO864542L publication Critical patent/NO864542L/no
Publication of NO165442B publication Critical patent/NO165442B/no
Publication of NO165442C publication Critical patent/NO165442C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/32—Sulfur atoms
    • C07D213/34—Sulfur atoms to which a second hetero atom is attached
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
NO864542A 1985-11-18 1986-11-14 Analogifremgangsmaate for fremstilling av bicykliske sulfonamid-derivater. NO165442C (no)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP25915485 1985-11-18
JP3013086 1986-02-13
JP11559986 1986-05-19
JP12901186 1986-06-03
JP16925786 1986-07-17

Publications (4)

Publication Number Publication Date
NO864542D0 NO864542D0 (no) 1986-11-14
NO864542L NO864542L (no) 1987-05-19
NO165442B NO165442B (no) 1990-11-05
NO165442C true NO165442C (no) 1991-02-13

Family

ID=27521199

Family Applications (1)

Application Number Title Priority Date Filing Date
NO864542A NO165442C (no) 1985-11-18 1986-11-14 Analogifremgangsmaate for fremstilling av bicykliske sulfonamid-derivater.

Country Status (20)

Country Link
US (6) US4861913A (no)
EP (1) EP0226346B1 (no)
JP (1) JPS63139161A (no)
CN (1) CN1019194B (no)
AR (1) AR245102A1 (no)
AT (1) ATE66207T1 (no)
AU (1) AU595554B2 (no)
CA (1) CA1278577C (no)
DE (1) DE3680884D1 (no)
DK (1) DK169918B1 (no)
ES (1) ES2051693T3 (no)
FI (1) FI90064C (no)
GB (1) GB2184118B (no)
GR (1) GR3002489T3 (no)
HU (1) HU203078B (no)
IE (1) IE58988B1 (no)
IL (1) IL80670A (no)
NO (1) NO165442C (no)
NZ (1) NZ218115A (no)
PT (1) PT83744B (no)

Families Citing this family (42)

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CA1278577C (en) * 1985-11-18 1991-01-02 Tatsuo Tsuri Bicyclic sulfonamide derivatives
GB8708233D0 (en) * 1987-04-07 1987-05-13 Smith Kline French Lab Pharmaceutically active compounds
CA1294974C (en) * 1987-05-08 1992-01-28 Sanji Hagishita Bicyclic sulfonamide derivatives and process therefor
GB8717374D0 (en) * 1987-07-22 1987-08-26 Smith Kline French Lab Pharmaceutically active compounds
EP0516181A1 (en) * 1987-10-23 1992-12-02 Ono Pharmaceutical Co., Ltd. Novel sulfonamide derivatives
JP2565746B2 (ja) * 1987-10-23 1996-12-18 小野薬品工業株式会社 新規な炭素環系スルホンアミド誘導体
EP0312906A3 (en) * 1987-10-23 1990-09-05 Ono Pharmaceutical Co., Ltd. Novel sulfonamide derivatives
EP0516180A1 (en) * 1988-04-19 1992-12-02 Ono Pharmaceutical Co., Ltd. Novel sulfonamide derivatives
CA1332607C (en) * 1988-07-19 1994-10-18 Masayuki Narisada Alkenyltetrazole derivatives
US5117039A (en) * 1988-12-14 1992-05-26 Shionogi & Co., Ltd. Monoesters of arylacetic acid and the process thereof
US5241104A (en) * 1988-12-14 1993-08-31 Shionogi & Co., Ltd. Mono ester of dicarboxylic acid and process thereof
US5008409A (en) * 1988-12-14 1991-04-16 Shionogi & Co., Ltd. Process for preparing 1,4-bridged cyclohexane carboxylic acid derivatives
KR0138528B1 (en) * 1988-12-14 1998-05-01 Shionogi Seiyaku Kk Preparation of 2,3-trans-1,4-bridged cyclohexane sulfonamide derivatives
US5047574A (en) * 1988-12-14 1991-09-10 Shionogi & Co., Ltd. Certain optically active mono esters of dicarboxylic acids
JP2756689B2 (ja) * 1989-02-20 1998-05-25 塩野義製薬株式会社 置換ヘキセン酸誘導体
ES2104612T3 (es) * 1989-10-18 1997-10-16 Shionogi & Co Procedimiento de preparacion de derivados de sulfonamida de norbornano.
US5763647A (en) * 1990-03-30 1998-06-09 Shionogi & Co., Ltd. Preparation of optically active 1,4-bridged-cyclohexane carboxylic acid derivatives
JP2891740B2 (ja) * 1990-03-30 1999-05-17 塩野義製薬株式会社 光学活性ノルボルナン系アミン誘導体の製造方法
JP2984077B2 (ja) * 1990-04-19 1999-11-29 塩野義製薬株式会社 スルホニルアミノ置換ビシクロ環系ヒドロキサム酸誘導体
FR2665440B1 (fr) * 1990-07-31 1994-02-04 Lipha Nouveaux cycloalkylsulfonamides substitues, procedes de preparation et medicaments les contenant.
US5550248A (en) * 1990-11-29 1996-08-27 E.R. Squibb & Sons, Inc. Substituted stryl heterocyclic amido prostaglandin analogs
US5334369A (en) * 1991-06-11 1994-08-02 Medical University Of South Carolina Platelet receptor antagonists useful in detecting intravascular platelet aggregation
US5827868A (en) * 1991-10-07 1998-10-27 E. R. Squibb & Sons, Inc. Prostaglandin analogs
CA2113787A1 (en) * 1993-01-29 1994-07-30 Nobuyuki Hamanaka Carbocyclic sulfonamides
EA000987B1 (ru) * 1995-06-21 2000-08-28 Сионоги Энд Ко., Лтд. Бициклические аминопроизводные и содержащие их антагонисты pgd2
IL118727A (en) * 1995-06-29 2003-01-12 Lilly Co Eli (-)-2-spiro-5-hydantoinbicyclo [3.1.0] hexane-6-carboxylic acid, salts thereof and use thereof for the preparation of (+)-(2) aminobicyclo [3.1.0] hexane-2,6-dicarboxylic acid
BR9611521A (pt) * 1995-11-16 1999-06-29 Lilly Co Eli Antagonistas de receptor de aminoácido excitador
ZA969485B (en) * 1995-11-16 1998-05-12 Lilly Co Eli Excitatory amino acid receptor antagonists.
US6056974A (en) * 1996-04-26 2000-05-02 Shionogi & Co., Ltd. Rapid-release S1452 tablets
EP0945450B1 (en) * 1996-12-12 2005-05-11 Shionogi & Co., Ltd. Fused heterocyclic benzenecarboxylic acid amide derivatives and pgd2 antagonists containing the same
BR9714016A (pt) * 1996-12-13 2000-02-29 Shionogi & Co Derivados de benzotiofenocarboxamida e antagonistas a pgd2, que compreendem os mesmos
ZA984040B (en) 1997-05-15 1998-11-20 Ono Pharmaceutical Co Benzenesulfonamide compounds
AU8998298A (en) 1997-09-19 1999-04-12 Shionogi & Co., Ltd. Compounds having (2.2.1)bicyclo skeleton
PL197331B1 (pl) * 1998-03-31 2008-03-31 Shionogi & Co Sposób wytwarzania pochodnych kwasów 5-hydroksybenzo [b] -tiofeno-3-karboksylowych
PA8469401A1 (es) * 1998-04-10 2000-05-24 Pfizer Prod Inc Derivados biciclicos del acido hidroxamico
WO2000030683A1 (fr) * 1998-11-19 2000-06-02 Shionogi & C0., Ltd. Composes prophylactiques et/ou therapeutiques destines a des maladies du systeme nerveux central et possedant des composes antagonistes du recepteur de txa2 et/ou inhibiteurs de la txa2 synthase
JP2000351729A (ja) * 1999-06-08 2000-12-19 Shionogi & Co Ltd トロンボキサンａ２受容体拮抗剤の経皮吸収製剤
JP3910446B2 (ja) 1999-11-26 2007-04-25 塩野義製薬株式会社 Ｎｐｙｙ５拮抗剤
ATE346039T1 (de) * 2000-03-20 2006-12-15 Merck Sharp & Dohme Sulfonamido-substituierte verbrückte bicycloalkylderivative
US6727277B1 (en) 2002-11-12 2004-04-27 Kansas State University Research Foundation Compounds affecting cholesterol absorption
JP5861884B2 (ja) * 2012-03-29 2016-02-16 荒川化学工業株式会社 エキソ型ノルボルネン化合物の製造方法
CN110563006A (zh) * 2019-09-25 2019-12-13 新乡市锦源化工有限公司 一种对位酯生产中亚硫酸氢钠处理方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2004327A1 (de) * 1969-02-14 1970-09-03 F. Hoffmann-La Roche & Co Ag, Basel (Schweiz) Bornanocarboxamide
US3988362A (en) * 1972-08-10 1976-10-26 Hoffmann-La Roche Inc. Intermediates for preparation of 2,2,3-endotrimethyl-7-anti-amino-norbornanes
WO1980001381A1 (en) * 1979-01-05 1980-07-10 R Jones Substituted bicyclo (2,2,1) heptanes and hept-2-enes
EP0044711B1 (en) * 1980-07-22 1984-03-14 Ono Pharmaceutical Co., Ltd. 9,11-methano-13-aza-11a-carbathrombanoic acid analogues and pharmaceutical use thereof
JPS5813551A (ja) 1981-07-16 1983-01-26 Ono Pharmaceut Co Ltd １３−アザトロンボキサン類似化合物、その製造方法及びその化合物を有効成分として含有するトロンボキサン起因疾患治療剤
GB2113678B (en) * 1981-12-23 1985-06-19 Nat Res Dev Prostaglandins
US4456615A (en) * 1982-10-25 1984-06-26 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction
US4456616A (en) * 1982-12-27 1984-06-26 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction
US4647585A (en) * 1984-11-08 1987-03-03 E. R. Squibb & Sons, Inc. Bicycloheptane substituted ethers
US4663336A (en) * 1985-07-01 1987-05-05 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted diamide and its congener prostaglandin analogs useful in the treatment of thrombotic disease
US4654357A (en) * 1985-08-09 1987-03-31 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted sulfonamide prostaglandin analogs
CA1278577C (en) * 1985-11-18 1991-01-02 Tatsuo Tsuri Bicyclic sulfonamide derivatives
US4734424A (en) * 1986-09-24 1988-03-29 E. R. Squibb & Sons, Inc. Bicycloheptane substituted diamide and its congener prostaglandin analogs
CA1294974C (en) * 1987-05-08 1992-01-28 Sanji Hagishita Bicyclic sulfonamide derivatives and process therefor

Also Published As

Publication number Publication date
HUT44765A (en) 1988-04-28
JPS63139161A (ja) 1988-06-10
IE58988B1 (en) 1993-12-15
IL80670A0 (en) 1987-02-27
DK169918B1 (da) 1995-04-03
GB2184118B (en) 1990-01-17
FI864675A0 (fi) 1986-11-17
AR245102A1 (es) 1993-12-30
CN86108584A (zh) 1987-07-29
IE863002L (en) 1987-05-18
ATE66207T1 (de) 1991-08-15
NO864542L (no) 1987-05-19
CN1019194B (zh) 1992-11-25
AU6536086A (en) 1987-05-21
US4861913A (en) 1989-08-29
DE3680884D1 (de) 1991-09-19
US5043456A (en) 1991-08-27
PT83744A (en) 1986-12-01
US5043451A (en) 1991-08-27
HU203078B (en) 1991-05-28
DK549086A (da) 1987-05-19
GR3002489T3 (en) 1992-12-30
EP0226346A1 (en) 1987-06-24
FI90064C (fi) 1993-12-27
NO864542D0 (no) 1986-11-14
AU595554B2 (en) 1990-04-05
US4960909A (en) 1990-10-02
CA1278577C (en) 1991-01-02
DK549086D0 (da) 1986-11-17
EP0226346B1 (en) 1991-08-14
US5041635A (en) 1991-08-20
GB8627561D0 (en) 1986-12-17
IL80670A (en) 1991-06-10
ES2051693T3 (es) 1994-07-01
NO165442B (no) 1990-11-05
PT83744B (pt) 1988-08-17
FI864675A (fi) 1987-05-19
FI90064B (fi) 1993-09-15
US4976891A (en) 1990-12-11
JPH0579060B2 (no) 1993-11-01
NZ218115A (en) 1990-02-26
GB2184118A (en) 1987-06-17

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Legal Events

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