IL80434A - 5-aryl-2,4-dialkyl-3h-1,2,4-triazole-3-thiones and antidepressant pharmaceutical compositions containing them - Google Patents
5-aryl-2,4-dialkyl-3h-1,2,4-triazole-3-thiones and antidepressant pharmaceutical compositions containing themInfo
- Publication number
- IL80434A IL80434A IL80434A IL8043486A IL80434A IL 80434 A IL80434 A IL 80434A IL 80434 A IL80434 A IL 80434A IL 8043486 A IL8043486 A IL 8043486A IL 80434 A IL80434 A IL 80434A
- Authority
- IL
- Israel
- Prior art keywords
- thiones
- triazole
- dialkyl
- aryl
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79235985A | 1985-10-29 | 1985-10-29 | |
| US80761385A | 1985-12-11 | 1985-12-11 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL80434A0 IL80434A0 (en) | 1987-01-30 |
| IL80434A true IL80434A (en) | 1991-01-31 |
Family
ID=27121269
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL80434A IL80434A (en) | 1985-10-29 | 1986-10-28 | 5-aryl-2,4-dialkyl-3h-1,2,4-triazole-3-thiones and antidepressant pharmaceutical compositions containing them |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0221485B1 (es) |
| JP (1) | JPH07116162B2 (es) |
| KR (1) | KR900003879B1 (es) |
| CN (1) | CN1014993B (es) |
| AR (1) | AR243171A1 (es) |
| AU (1) | AU587646B2 (es) |
| CA (2) | CA1284997C (es) |
| DE (1) | DE3676632D1 (es) |
| DK (1) | DK164785C (es) |
| ES (1) | ES2031449T3 (es) |
| FI (1) | FI89047C (es) |
| GR (1) | GR3001246T3 (es) |
| HU (1) | HU196191B (es) |
| IE (1) | IE58969B1 (es) |
| IL (1) | IL80434A (es) |
| NO (1) | NO165542C (es) |
| NZ (1) | NZ218087A (es) |
| PH (2) | PH22377A (es) |
| PT (1) | PT83636B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR243169A1 (es) * | 1985-10-29 | 1993-07-30 | Merrell Pharma Inc | Procedimiento para preparar 5-naftil-2,4-dialquil-3h-1,2,4-triazol-3-tionas. |
| JP2593084B2 (ja) * | 1986-12-19 | 1997-03-19 | メレルダウファーマスーティカルズ インコーポレーテッド | ５−アリールー３ｈ−１，２，４−トリアゾールー３−オン類の神経変性障害の処置への用途 |
| JP2542880B2 (ja) * | 1986-12-19 | 1996-10-09 | メレルダウファーマスーティカルズ インコーポレーテッド | ５−アリ―ル−３ｈ−１，２，４，−トリアゾ―ル−３−オン類の抗痙攣剤としての用途 |
| EP0280867A1 (en) * | 1987-01-27 | 1988-09-07 | Merrell Dow Pharmaceuticals Inc. | Process for the preparation of 5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3-thiones |
| US4847276A (en) * | 1988-09-06 | 1989-07-11 | Merrell Dow Pharmaceuticals Inc. | Treatment of thromobocytosis with 5-(4-chlorophenyl)-2,4-diemthyl-3H-1,2,4-triazole-3-thione |
| DE69404322T2 (de) * | 1993-10-29 | 1997-10-30 | Merrell Pharma Inc | 3-aryl-4-alkyl und 4,5-dialkyl-4h-1,2,4-triazole, verwendbar gegen gedächtnis-störungen |
| AU700620B2 (en) * | 1994-07-07 | 1999-01-07 | Merrell Pharmaceuticals Inc. | Process for the preparation of 5-aryl-2,4-dialkyl-3 h-1,2,4-triazole-3-thiones |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR243169A1 (es) * | 1985-10-29 | 1993-07-30 | Merrell Pharma Inc | Procedimiento para preparar 5-naftil-2,4-dialquil-3h-1,2,4-triazol-3-tionas. |
| DK570987A (da) * | 1986-12-01 | 1988-06-02 | Hoffmann La Roche | Oxadiazol-, thiadiazol- og triazolforbindelser |
-
1986
- 1986-10-22 AR AR86305652A patent/AR243171A1/es active
- 1986-10-24 CA CA000521330A patent/CA1284997C/en not_active Expired - Lifetime
- 1986-10-24 PH PH34414A patent/PH22377A/en unknown
- 1986-10-24 AU AU64386/86A patent/AU587646B2/en not_active Ceased
- 1986-10-27 EP EP86114874A patent/EP0221485B1/en not_active Expired - Lifetime
- 1986-10-27 ES ES198686114874T patent/ES2031449T3/es not_active Expired - Lifetime
- 1986-10-27 DE DE8686114874T patent/DE3676632D1/de not_active Expired - Fee Related
- 1986-10-28 PT PT83636A patent/PT83636B/pt not_active IP Right Cessation
- 1986-10-28 NZ NZ218087A patent/NZ218087A/xx unknown
- 1986-10-28 DK DK514886A patent/DK164785C/da active
- 1986-10-28 JP JP61254829A patent/JPH07116162B2/ja not_active Expired - Lifetime
- 1986-10-28 NO NO864306A patent/NO165542C/no not_active IP Right Cessation
- 1986-10-28 KR KR1019860009007A patent/KR900003879B1/ko not_active IP Right Cessation
- 1986-10-28 CN CN86106880A patent/CN1014993B/zh not_active Expired
- 1986-10-28 IL IL80434A patent/IL80434A/xx not_active IP Right Cessation
- 1986-10-28 FI FI864377A patent/FI89047C/fi not_active IP Right Cessation
- 1986-10-28 IE IE283286A patent/IE58969B1/en not_active IP Right Cessation
- 1986-10-28 HU HU864526A patent/HU196191B/hu not_active IP Right Cessation
-
1987
- 1987-10-08 PH PH35910A patent/PH23275A/en unknown
-
1990
- 1990-08-07 CA CA000615808A patent/CA1301655C/en not_active Expired - Lifetime
- 1990-12-28 GR GR90401022T patent/GR3001246T3/el unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| RH | Patent void | ||
| HC | Change of name of proprietor(s) |
Owner name: AVENTIS INC. Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC. |