DE3676632D1 - 5-aryl-2,4-dialkyl-3h-1,2,4-triazol-3-thione und ihre verwendung als antidepressiva. - Google Patents
5-aryl-2,4-dialkyl-3h-1,2,4-triazol-3-thione und ihre verwendung als antidepressiva.Info
- Publication number
- DE3676632D1 DE3676632D1 DE8686114874T DE3676632T DE3676632D1 DE 3676632 D1 DE3676632 D1 DE 3676632D1 DE 8686114874 T DE8686114874 T DE 8686114874T DE 3676632 T DE3676632 T DE 3676632T DE 3676632 D1 DE3676632 D1 DE 3676632D1
- Authority
- DE
- Germany
- Prior art keywords
- antidepressive
- thione
- triazol
- dialkyl
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79235985A | 1985-10-29 | 1985-10-29 | |
US80761385A | 1985-12-11 | 1985-12-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3676632D1 true DE3676632D1 (de) | 1991-02-07 |
Family
ID=27121269
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8686114874T Expired - Fee Related DE3676632D1 (de) | 1985-10-29 | 1986-10-27 | 5-aryl-2,4-dialkyl-3h-1,2,4-triazol-3-thione und ihre verwendung als antidepressiva. |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0221485B1 (de) |
JP (1) | JPH07116162B2 (de) |
KR (1) | KR900003879B1 (de) |
CN (1) | CN1014993B (de) |
AR (1) | AR243171A1 (de) |
AU (1) | AU587646B2 (de) |
CA (2) | CA1284997C (de) |
DE (1) | DE3676632D1 (de) |
DK (1) | DK164785C (de) |
ES (1) | ES2031449T3 (de) |
FI (1) | FI89047C (de) |
GR (1) | GR3001246T3 (de) |
HU (1) | HU196191B (de) |
IE (1) | IE58969B1 (de) |
IL (1) | IL80434A (de) |
NO (1) | NO165542C (de) |
NZ (1) | NZ218087A (de) |
PH (2) | PH22377A (de) |
PT (1) | PT83636B (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR243169A1 (es) * | 1985-10-29 | 1993-07-30 | Merrell Pharma Inc | Procedimiento para preparar 5-naftil-2,4-dialquil-3h-1,2,4-triazol-3-tionas. |
PH24094A (en) * | 1986-12-19 | 1990-03-05 | Merrell Dow Pharma | 5-aryl-3h-1,2,4-triazol-3-ones and their use as anticonvulsants |
JP2593084B2 (ja) * | 1986-12-19 | 1997-03-19 | メレルダウファーマスーティカルズ インコーポレーテッド | 5−アリールー3h−1,2,4−トリアゾールー3−オン類の神経変性障害の処置への用途 |
EP0280867A1 (de) * | 1987-01-27 | 1988-09-07 | Merrell Dow Pharmaceuticals Inc. | Verfahren zur Herstellung von 5-aryl-2,4-dialkyl-3H-1,2,4-triazol-3-thione |
US4847276A (en) * | 1988-09-06 | 1989-07-11 | Merrell Dow Pharmaceuticals Inc. | Treatment of thromobocytosis with 5-(4-chlorophenyl)-2,4-diemthyl-3H-1,2,4-triazole-3-thione |
DE69404322T2 (de) * | 1993-10-29 | 1997-10-30 | Merrell Pharma Inc | 3-aryl-4-alkyl und 4,5-dialkyl-4h-1,2,4-triazole, verwendbar gegen gedächtnis-störungen |
WO1996001812A1 (en) * | 1994-07-07 | 1996-01-25 | Merrell Pharmaceuticals Inc. | Process for the preparation of 5-aryl-2,4-dialkyl-3h-1,2,4-triazole-3-thiones |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR243169A1 (es) * | 1985-10-29 | 1993-07-30 | Merrell Pharma Inc | Procedimiento para preparar 5-naftil-2,4-dialquil-3h-1,2,4-triazol-3-tionas. |
DK570987A (da) * | 1986-12-01 | 1988-06-02 | Hoffmann La Roche | Oxadiazol-, thiadiazol- og triazolforbindelser |
-
1986
- 1986-10-22 AR AR86305652A patent/AR243171A1/es active
- 1986-10-24 AU AU64386/86A patent/AU587646B2/en not_active Ceased
- 1986-10-24 PH PH34414A patent/PH22377A/en unknown
- 1986-10-24 CA CA000521330A patent/CA1284997C/en not_active Expired - Lifetime
- 1986-10-27 EP EP86114874A patent/EP0221485B1/de not_active Expired - Lifetime
- 1986-10-27 ES ES198686114874T patent/ES2031449T3/es not_active Expired - Lifetime
- 1986-10-27 DE DE8686114874T patent/DE3676632D1/de not_active Expired - Fee Related
- 1986-10-28 HU HU864526A patent/HU196191B/hu not_active IP Right Cessation
- 1986-10-28 CN CN86106880A patent/CN1014993B/zh not_active Expired
- 1986-10-28 NZ NZ218087A patent/NZ218087A/xx unknown
- 1986-10-28 PT PT83636A patent/PT83636B/pt not_active IP Right Cessation
- 1986-10-28 NO NO864306A patent/NO165542C/no not_active IP Right Cessation
- 1986-10-28 KR KR1019860009007A patent/KR900003879B1/ko not_active IP Right Cessation
- 1986-10-28 IE IE283286A patent/IE58969B1/en not_active IP Right Cessation
- 1986-10-28 DK DK514886A patent/DK164785C/da active
- 1986-10-28 IL IL80434A patent/IL80434A/xx not_active IP Right Cessation
- 1986-10-28 JP JP61254829A patent/JPH07116162B2/ja not_active Expired - Lifetime
- 1986-10-28 FI FI864377A patent/FI89047C/fi not_active IP Right Cessation
-
1987
- 1987-10-08 PH PH35910A patent/PH23275A/en unknown
-
1990
- 1990-08-07 CA CA000615808A patent/CA1301655C/en not_active Expired - Lifetime
- 1990-12-28 GR GR90401022T patent/GR3001246T3/el unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |