IL74865A - 4'-amino-9a-aza-9a-homoerythromycin derivatives and pharmaceutical compositions containing them - Google Patents

4'-amino-9a-aza-9a-homoerythromycin derivatives and pharmaceutical compositions containing them

Info

Publication number
IL74865A
IL74865A IL74865A IL7486585A IL74865A IL 74865 A IL74865 A IL 74865A IL 74865 A IL74865 A IL 74865A IL 7486585 A IL7486585 A IL 7486585A IL 74865 A IL74865 A IL 74865A
Authority
IL
Israel
Prior art keywords
aza
amino
pharmaceutical compositions
compositions containing
homoerythromycin
Prior art date
Application number
IL74865A
Other languages
English (en)
Other versions
IL74865A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/600,252 external-priority patent/US4512982A/en
Application filed by Pfizer filed Critical Pfizer
Publication of IL74865A0 publication Critical patent/IL74865A0/xx
Publication of IL74865A publication Critical patent/IL74865A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL74865A 1984-04-13 1985-04-10 4'-amino-9a-aza-9a-homoerythromycin derivatives and pharmaceutical compositions containing them IL74865A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/600,252 US4512982A (en) 1984-04-13 1984-04-13 9α-Aza-9α-homoerythromycin compounds, pharmaceutical composition and therapeutic method
US06/616,529 US4518590A (en) 1984-04-13 1984-06-04 9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method

Publications (2)

Publication Number Publication Date
IL74865A0 IL74865A0 (en) 1985-07-31
IL74865A true IL74865A (en) 1987-12-31

Family

ID=27083554

Family Applications (1)

Application Number Title Priority Date Filing Date
IL74865A IL74865A (en) 1984-04-13 1985-04-10 4'-amino-9a-aza-9a-homoerythromycin derivatives and pharmaceutical compositions containing them

Country Status (19)

Country Link
US (1) US4518590A (es)
EP (1) EP0159856B1 (es)
KR (1) KR860002111B1 (es)
AU (1) AU549235B2 (es)
CA (1) CA1234805A (es)
DE (1) DE3565267D1 (es)
DK (1) DK164785A (es)
EG (1) EG17459A (es)
ES (3) ES8607335A1 (es)
FI (1) FI851449L (es)
GR (1) GR850900B (es)
HU (1) HU195668B (es)
IE (1) IE57739B1 (es)
IL (1) IL74865A (es)
NO (1) NO161497C (es)
NZ (1) NZ211769A (es)
PH (1) PH21185A (es)
PT (1) PT80270B (es)
YU (3) YU62385A (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075289A (en) * 1988-06-07 1991-12-24 Abbott Laboratories 9-r-azacyclic erythromycin antibiotics
US4904644A (en) * 1988-08-03 1990-02-27 Schering Corporation Antimicrobial compound isolated from Actinomadura fulva subsp indica
US5912331A (en) * 1991-03-15 1999-06-15 Merck & Co., Inc. Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A
CA2062932A1 (en) 1991-03-15 1992-09-16 Robert R. Wilkening 9-deoxo-9(z)-hydroxyiminoerythromycin a and o-derivatives thereof
US5985844A (en) * 1992-03-26 1999-11-16 Merck & Co., Inc. Homoerythromycin A derivatives modified at the 4"-and 8A-positions
KR100222014B1 (ko) * 1991-04-09 1999-10-01 스티븐 에프. 웨인스톡 거대환식 락탐 유도체, 이의 제조방법 및 이를 포함하는 약제학적 조성물
US5189159A (en) * 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers
US5523399A (en) * 1991-12-27 1996-06-04 Taisho Pharmaceutical Co., Ltd. 5-O-desosaminylerythronolide derivatives
US5215980A (en) * 1992-01-17 1993-06-01 Merck & Co., Inc. 10-AZA-9-deoxo-11-deoxy-erythromycin A and derivatives thereof
US5210235A (en) * 1992-08-26 1993-05-11 Merck & Co., Inc. Methods of elaborating erythromycin fragments into amine-containing fragments of azalide antibiotics
US5332807A (en) * 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
ATE154806T1 (de) * 1993-05-19 1997-07-15 Pfizer Zwischenprodukt für azithromycin
US5441939A (en) * 1994-03-04 1995-08-15 Pfizer Inc. 3"-desmethoxy derivatives of erythromycin and azithromycin
FR2739620B1 (fr) * 1995-10-09 1997-12-19 Roussel Uclaf Nouveaux derives de la 5-0-desosaminyl 6-o-methyl erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
USRE38426E1 (en) * 1995-10-09 2004-02-10 Aventis Pharma S.A. 5-O-deosaminyl 6-O-methyl erythronolide A derivatives, preparation method therefor and use thereof for preparing biologically active materials
JP2004506664A (ja) 2000-08-23 2004-03-04 ウォックハート・リミテッド 無水アジトロマイシンの製造法
JP4104463B2 (ja) 2001-04-27 2008-06-18 ファイザー・プロダクツ・インク ４’’−置換された−９−デオキソ−９ａ−アザ−９ａ−ホモエリスロマイシン誘導体を製造するための方法
EP1483579A4 (en) 2002-02-15 2006-07-12 Merckle Gmbh CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS, METHODS FOR THE PREPARATION AND USE OF CONJUGATES, FORMULATION AND PHARMACEUTICAL APPLICATIONS OBTAINED FROM SUCH CONJUGATES
AU2003219770B2 (en) 2002-02-15 2008-10-09 Merckle Gmbh Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
US7271154B2 (en) 2002-02-15 2007-09-18 Merckle Gmbh Antibiotic conjugates
GB0310992D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
US7468428B2 (en) * 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
US20060116336A1 (en) * 2004-03-17 2006-06-01 American Pharmaceutical Partners, Inc. Lyophilized azithromycin formulation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE445223B (sv) * 1977-02-04 1986-06-09 Pfizer Sett att framstella 4"-amino-erytomylin-a-derivat
US4150220A (en) * 1977-02-04 1979-04-17 Pfizer Inc. Semi-synthetic 4"-erythromycin A derivatives
US4180654A (en) * 1978-01-03 1979-12-25 Pfizer Inc. 4"-Deoxy-4"-acylamido derivatives of oleandomycin, erythromycin and erythromycin carbonate
YU43116B (en) * 1979-04-02 1989-04-30 Pliva Pharm & Chem Works Process for preparing 11-aza-4-o-cladinosyl-6-o-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane-2-one(11-aza-10-deox
YU43006B (en) * 1981-03-06 1989-02-28 Pliva Pharm & Chem Works Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
US4465674A (en) * 1983-09-06 1984-08-14 Pfizer Inc. Azahomoerythromycin D derivative and intermediates therefor

Also Published As

Publication number Publication date
KR850007435A (ko) 1985-12-04
IL74865A0 (en) 1985-07-31
EP0159856A3 (en) 1986-03-19
YU126787A (en) 1988-02-29
FI851449A0 (fi) 1985-04-11
FI851449L (fi) 1985-10-14
GR850900B (es) 1985-11-25
ES8705458A1 (es) 1987-05-01
ES542134A0 (es) 1986-06-16
PH21185A (en) 1987-08-12
YU126887A (en) 1988-02-29
EP0159856A2 (en) 1985-10-30
DK164785D0 (da) 1985-04-12
NO161497C (no) 1989-08-23
KR860002111B1 (ko) 1986-11-26
NO851466L (no) 1985-10-14
CA1234805A (en) 1988-04-05
AU549235B2 (en) 1986-01-23
PT80270A (en) 1985-05-01
DK164785A (da) 1985-12-10
ES551503A0 (es) 1987-04-16
PT80270B (pt) 1987-10-20
IE57739B1 (en) 1993-03-24
NZ211769A (en) 1987-10-30
US4518590A (en) 1985-05-21
ES8607335A1 (es) 1986-06-16
HUT37629A (en) 1986-01-23
YU62385A (en) 1988-02-29
DE3565267D1 (en) 1988-11-03
ES551502A0 (es) 1987-05-01
EG17459A (en) 1992-12-30
ES8704965A1 (es) 1987-04-16
HU195668B (en) 1988-06-28
AU4107085A (en) 1985-10-17
NO161497B (no) 1989-05-16
EP0159856B1 (en) 1988-09-28
IE850912L (en) 1985-10-13

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Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
EXP Patent expired