IL74545A - Synthetic hepatitis b virus vaccine including both t cell and b cell determinants - Google Patents

Synthetic hepatitis b virus vaccine including both t cell and b cell determinants

Info

Publication number
IL74545A
IL74545A IL74545A IL7454585A IL74545A IL 74545 A IL74545 A IL 74545A IL 74545 A IL74545 A IL 74545A IL 7454585 A IL7454585 A IL 7454585A IL 74545 A IL74545 A IL 74545A
Authority
IL
Israel
Prior art keywords
cell
hepatitis
virus vaccine
determinants
vaccine including
Prior art date
Application number
IL74545A
Other languages
English (en)
Other versions
IL74545A0 (en
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/588,122 external-priority patent/US4599230A/en
Priority claimed from US06/587,983 external-priority patent/US4599231A/en
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Priority to IL90035A priority Critical patent/IL90035A/xx
Publication of IL74545A0 publication Critical patent/IL74545A0/xx
Priority to IL90035A priority patent/IL90035A0/xx
Publication of IL74545A publication Critical patent/IL74545A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Air Bags (AREA)
  • Selective Calling Equipment (AREA)
IL74545A 1984-03-09 1985-03-08 Synthetic hepatitis b virus vaccine including both t cell and b cell determinants IL74545A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IL90035A IL90035A (en) 1984-03-09 1985-03-08 Synthetic multimeric hepatitis b virus vaccine including both t cell and b cell determinants
IL90035A IL90035A0 (en) 1984-03-09 1989-04-19 Synthetic hepatitis b virus vaccine including both t cell and b cell determinants

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/588,122 US4599230A (en) 1984-03-09 1984-03-09 Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
US06/587,983 US4599231A (en) 1984-03-09 1984-03-09 Synthetic hepatitis B virus vaccine including both T cell and B cell determinants

Publications (2)

Publication Number Publication Date
IL74545A0 IL74545A0 (en) 1985-06-30
IL74545A true IL74545A (en) 1990-11-05

Family

ID=27080174

Family Applications (3)

Application Number Title Priority Date Filing Date
IL74545A IL74545A (en) 1984-03-09 1985-03-08 Synthetic hepatitis b virus vaccine including both t cell and b cell determinants
IL90035A IL90035A (en) 1984-03-09 1985-03-08 Synthetic multimeric hepatitis b virus vaccine including both t cell and b cell determinants
IL90035A IL90035A0 (en) 1984-03-09 1989-04-19 Synthetic hepatitis b virus vaccine including both t cell and b cell determinants

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL90035A IL90035A (en) 1984-03-09 1985-03-08 Synthetic multimeric hepatitis b virus vaccine including both t cell and b cell determinants
IL90035A IL90035A0 (en) 1984-03-09 1989-04-19 Synthetic hepatitis b virus vaccine including both t cell and b cell determinants

Country Status (11)

Country Link
EP (1) EP0155146B1 (de)
AT (1) ATE82135T1 (de)
AU (2) AU579148B2 (de)
CA (1) CA1253069A (de)
DE (1) DE3586801D1 (de)
DK (1) DK516385A (de)
FI (1) FI84558C (de)
IL (3) IL74545A (de)
NO (1) NO167359C (de)
NZ (2) NZ211356A (de)
WO (1) WO1985004103A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2560890B1 (fr) * 1984-03-07 1987-10-16 Grp Genie Genetique Composition utile pour la fabrication de vaccins contenant des particules portant l'antigene de surface du virus de l'hepatite b et le recepteur de l'albumine serique humaine polymerisee, cellules animales capables de produire de telles particules et procede pour leur obtention
WO1987007896A1 (en) * 1986-06-20 1987-12-30 Scripps Clinic And Research Foundation T and b cell epitopes of the pre-s region of hepatitis b virus surface antigen
US6054438A (en) * 1987-01-07 2000-04-25 Imperial Cancer Research Technology Limited Nucleic acid fragments encoding portions of the core protein of the human mammary epithelial mucin
EP0293201A3 (de) * 1987-05-26 1990-02-28 The Wistar Institute Methode zur Impfung gegen Hepatitis-B-Virus
CA1341074C (en) * 1987-06-22 2000-08-08 Hans A. Thoma Hbv surface antigen particles, prepared by recombinant dna processes, composed of different epitopes, selected from the pre-s and s-peptides as a new vaccine
EP0375740A1 (de) * 1987-09-04 1990-07-04 Whitehead Institute For Biomedical Research Peptidkomplexe mit erhöhter stabilität
EP0491077A1 (de) * 1990-12-19 1992-06-24 Medeva Holdings B.V. Zusammensetzung verwendbar als therapeutisches Mittel gegen chronische virale Leberkrankheiten
GB9325772D0 (en) * 1993-12-16 1994-02-16 Smithkline Beecham Biolog Novel compounds
JP2000514643A (ja) * 1996-04-18 2000-11-07 アボツト・ラボラトリーズ Ｂ型肝炎表面抗原のａ―決定基の抗原エピトープ及びその利用法
EP1860192A1 (de) 1996-09-17 2007-11-28 Novartis Vaccines and Diagnostics, Inc. Zusammensetzungen und Verfahren zur Behandlung intrazellulärer Erkrankungen
CA2274585A1 (en) * 1996-12-30 1998-07-09 Innogenetics N.V. Annexin v-binding polypeptides derived from hbsag and their uses
US6881723B1 (en) 1998-11-05 2005-04-19 Powderject Vaccines, Inc. Nucleic acid constructs
ES2330904B1 (es) 2005-09-21 2010-09-23 Fundacio Centre De Recerca En Sanitat Animal Polinucleotidos de haemophilus parasuis y su uso.
EP2476437B1 (de) 2006-08-11 2018-11-28 Life Sciences Research Partners VZW Immunogene Peptide und deren Verwendung bei Immunerkrankungen
EP2244733B1 (de) 2008-02-14 2015-06-17 Life Sciences Research Partners VZW Auf intrazelluläre pathogene abzielende immuntherapie
AU2009214039B2 (en) 2008-02-14 2013-09-19 Katholieke Universiteit Leuven Immunogenic control of tumours and tumour cells
ES2924027T3 (es) 2010-11-25 2022-10-04 Imcyse Sa Péptidos inmunogénicos para su uso en la prevención y/o tratamiento de enfermedades infecciosas, enfermedades autoinmunitarias, respuestas inmunitarias a alofactores, enfermedades alérgicas, tumores, rechazo de injerto y respuestas inmunitarias contra vectores virales usados para terapia génica o vacunación génica
GB201201511D0 (en) 2012-01-30 2012-03-14 Univ Leuven Kath Modified epitopes for boosting CD4+ T-cell responses
KR101944263B1 (ko) * 2012-06-11 2019-02-01 시아먼 유니버시티 에이치비브이 감염 및 관련 질병의 치료를 위한 폴리펩타이드 및 항체
GB201309469D0 (en) 2013-05-28 2013-07-10 Imcyse Sa Detection of CD4+ T lymphocytes
US10729791B2 (en) 2015-05-18 2020-08-04 Imcyse Sa Animal models for evaluating pharmaceutical compounds
WO2017050966A1 (en) 2015-09-25 2017-03-30 Imcyse Sa Improved methods and compounds for eliminating immune responses to therapeutic agents
RU2018136760A (ru) 2016-04-19 2020-05-19 Имсис Са НОВЫЕ ИММУНОГЕННЫЕ CD1d-СВЯЗЫВАЮЩИЕ ПЕПТИДЫ
KR102358577B1 (ko) 2017-02-17 2022-02-04 시아먼 유니버시티 타겟 폴리펩티드를 제시하는 펩티드 캐리어 및 이의 용도

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA792485B (en) * 1978-06-07 1980-06-25 New York Blood Center Inc Vaccine for active immunization containing hepatitis b surface and/or e-antigens
FR2480779B2 (fr) * 1979-08-30 1986-07-18 Anvar Vecteur contenant une sequence nucleotidique de l'antigene de surface du virus de l'hepatite b et procede de fabrication d'une molecule immunogene mettant en oeuvre ce vecteur
DK171727B1 (da) * 1978-12-22 1997-04-14 Biogen Inc Rekombinante hepatitis B virus DNA-molekyler, værtsorganismer transformeret hermed, HBV-antigenspecifikke polypeptider, DNA-sekvenser kodende for HBV-antigenspecifikke polypeptider, metoder til påvisning af hepatitis B virus-antistoffer, metoder til fremstilling af nævnte DNA-molekyler, fremgangsmåder til fremstilling af nævnte polypeptider og midler til påvisning af HBV-infektion
US4415491A (en) * 1980-01-14 1983-11-15 The Regents Of The University Of California Synthetic vaccine peptide epitomes of hepatitis B surface antigen
FI83662C (fi) * 1980-07-17 1991-08-12 Scripps Clinic Res Diagnostik antikropp och foerfarande foer dess framstaellning.
IL61904A (en) * 1981-01-13 1985-07-31 Yeda Res & Dev Synthetic vaccine against influenza virus infections comprising a synthetic peptide and process for producing same
EP0082789B1 (de) * 1981-12-22 1987-04-08 Baylor College of Medicine Immunologische Zusammensetzung und Methode für Hepatitis-B-Virus
US4483793A (en) * 1982-10-04 1984-11-20 The Regents Of The University Of California Dimeric oligopeptides as heptenic epitopic sites for hepatitis
JPS5974985A (ja) * 1982-10-19 1984-04-27 Takeda Chem Ind Ltd 新規ｄｎａ
NZ207394A (en) * 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids

Also Published As

Publication number Publication date
NO167359B (no) 1991-07-22
DE3586801D1 (de) 1992-12-17
FI84558B (fi) 1991-09-13
FI854396A0 (fi) 1985-11-07
FI854396A (fi) 1985-11-07
EP0155146A2 (de) 1985-09-18
NZ211356A (en) 1990-07-26
ATE82135T1 (de) 1992-11-15
IL90035A0 (en) 1989-12-15
EP0155146A3 (en) 1988-01-20
IL74545A0 (en) 1985-06-30
AU4115985A (en) 1985-10-11
DK516385D0 (da) 1985-11-08
FI84558C (fi) 1991-12-27
AU2682388A (en) 1989-05-25
AU579148B2 (en) 1988-11-17
EP0155146B1 (de) 1992-11-11
WO1985004103A1 (en) 1985-09-26
AU623106B2 (en) 1992-05-07
NO854460L (no) 1986-01-08
NO167359C (no) 1991-10-30
DK516385A (da) 1985-11-08
IL90035A (en) 1990-11-05
NZ227731A (en) 1990-07-26
CA1253069A (en) 1989-04-25

Similar Documents

Publication Publication Date Title
IL90035A0 (en) Synthetic hepatitis b virus vaccine including both t cell and b cell determinants
EP0271302A3 (de) T-Zell-Epitope von Hepatitis-B-Virus-Nukleocapsid-Protein
IE873314L (en) T cell epitopes of the hepatitis b virus nucleocapsid¹protein
ES8105388A1 (es) Un metodo para mantener, replicar y expresar por lo menos una porcion del genoma de un virus n.p.
IL86832A0 (en) Recombinant dna molecules,host cells containing the same,immunogenic particles,pharmaceutical compositions containing the same and processes for the preparation thereof
WO1993015205A3 (en) Synthetic haemophilus influenzae conjugate vaccine
AU3473489A (en) Expression of hepatisis b s and pres2proteins in methylotrophic yeasts
ES555124A0 (es) Procedimiento de preparar particulas que contienen secuencias de aminoacidos y que tienen propiedades inmunogenas
AU4446593A (en) Recombinant adenovirus vaccines
ZA861767B (en) Process for preparing hepatitis b surface antigen containing particles in novel forms which are highly immunogenic
NZ508892A (en) Nucleic acid encoding a vaccine-induced mutant major surface antigen of a hepatitis B viral strain
EP0317279A3 (de) Peptide für die Verwendung zur Reinigung von Faktor-VIII
EP0485347A3 (en) Recombinant hepatitis delta antigen, process for the purification and use thereof
ES8801127A1 (es) Un procedimiento para preparar una vacuna auto antigena en forma de virus modificado de la viruela vacuna.
SU1380209A1 (ru) РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК PUR 291-HAV 22, КОДИРУЮЩАЯ СИНТЕЗ ГИБРИДНОГО ПОЛИПЕПТИДА АНТИГЕННЫХ ДЕТЕРМИНАНТ ВИРУСА ГЕПАТИТА А С β -ГАЛАКТОЗИДАЗОЙ
NZ230996A (en) Immunogenic recombinant polypeptides and their use in the production of neutralising antibodies against viral haemorrhagic septicaemia virus
Makela A study of the antigenicity and immunogenicity of the measles virus surface proteins
ES8801958A1 (es) Un procedimiento para la determinacion de virus de sida
PT89041A (pt) Metodo de preparacao de diagnosticos e vacinas nanbv