FI854396A - Syntetisk hepatitis b-virus vaccin som innehaoller baode t-cellens och b-cellens determinanter. - Google Patents

Syntetisk hepatitis b-virus vaccin som innehaoller baode t-cellens och b-cellens determinanter. Download PDF

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Publication number
FI854396A
FI854396A FI854396A FI854396A FI854396A FI 854396 A FI854396 A FI 854396A FI 854396 A FI854396 A FI 854396A FI 854396 A FI854396 A FI 854396A FI 854396 A FI854396 A FI 854396A
Authority
FI
Finland
Prior art keywords
cellens
virus
determinanter
baode
vaccin
Prior art date
Application number
FI854396A
Other languages
English (en)
Other versions
FI854396A0 (fi
FI84558C (fi
FI84558B (fi
Inventor
David R Milich
Frank V Chisari
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/588,122 external-priority patent/US4599230A/en
Priority claimed from US06/587,983 external-priority patent/US4599231A/en
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Publication of FI854396A publication Critical patent/FI854396A/fi
Publication of FI854396A0 publication Critical patent/FI854396A0/fi
Application granted granted Critical
Publication of FI84558B publication Critical patent/FI84558B/fi
Publication of FI84558C publication Critical patent/FI84558C/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Air Bags (AREA)
  • Selective Calling Equipment (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FI854396A 1984-03-09 1985-11-07 Foerfarande foer framstaellning av ett vaccin mot hepatitis b-virus. FI84558C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US58812284 1984-03-09
US06/588,122 US4599230A (en) 1984-03-09 1984-03-09 Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
US06/587,983 US4599231A (en) 1984-03-09 1984-03-09 Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
US58798384 1984-03-09
PCT/US1985/000360 WO1985004103A1 (en) 1984-03-09 1985-03-06 Synthetic hepatitis b virus vaccine including both t cell anc b cell determinants
US8500360 1985-03-06

Publications (4)

Publication Number Publication Date
FI854396A true FI854396A (fi) 1985-11-07
FI854396A0 FI854396A0 (fi) 1985-11-07
FI84558B FI84558B (fi) 1991-09-13
FI84558C FI84558C (fi) 1991-12-27

Family

ID=27080174

Family Applications (1)

Application Number Title Priority Date Filing Date
FI854396A FI84558C (fi) 1984-03-09 1985-11-07 Foerfarande foer framstaellning av ett vaccin mot hepatitis b-virus.

Country Status (11)

Country Link
EP (1) EP0155146B1 (fi)
AT (1) ATE82135T1 (fi)
AU (2) AU579148B2 (fi)
CA (1) CA1253069A (fi)
DE (1) DE3586801D1 (fi)
DK (1) DK516385A (fi)
FI (1) FI84558C (fi)
IL (3) IL74545A (fi)
NO (1) NO167359C (fi)
NZ (2) NZ227731A (fi)
WO (1) WO1985004103A1 (fi)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2560890B1 (fr) * 1984-03-07 1987-10-16 Grp Genie Genetique Composition utile pour la fabrication de vaccins contenant des particules portant l'antigene de surface du virus de l'hepatite b et le recepteur de l'albumine serique humaine polymerisee, cellules animales capables de produire de telles particules et procede pour leur obtention
AU617292B2 (en) * 1986-06-20 1991-11-28 Scripps Clinic And Research Foundation T and b cell epitopes of the pre-s region of hepatitis b virus surface antigen
US6222020B1 (en) * 1987-01-07 2001-04-24 Imperial Cancer Research Technology Limited Antigens derived from the core protein of the human mammary epithelial mucin
EP0293201A3 (en) * 1987-05-26 1990-02-28 The Wistar Institute Method of vaccination for hepatitis b virus
WO1988010300A1 (en) * 1987-06-22 1988-12-29 Medico Labs Ag Heterologous viral peptide particle immunogens
WO1989001943A1 (en) * 1987-09-04 1989-03-09 Whitehead Institute For Biomedical Research Peptide complexes having enhanced stability
EP0491077A1 (en) * 1990-12-19 1992-06-24 Medeva Holdings B.V. A composition used as a therapeutic agent against chronic viral hepatic diseases
GB9325772D0 (en) * 1993-12-16 1994-02-16 Smithkline Beecham Biolog Novel compounds
JP2000514643A (ja) * 1996-04-18 2000-11-07 アボツト・ラボラトリーズ B型肝炎表面抗原のa―決定基の抗原エピトープ及びその利用法
WO1998012332A1 (en) 1996-09-17 1998-03-26 Chiron Corporation Compositions and methods for treating intracellular diseases
WO1998029442A1 (en) * 1996-12-30 1998-07-09 Innogenetics N.V. ANNEXIN V-BINDING POLYPEPTIDES DERIVED FROM HBsAg AND THEIR USES
US6881723B1 (en) 1998-11-05 2005-04-19 Powderject Vaccines, Inc. Nucleic acid constructs
ES2330904B1 (es) 2005-09-21 2010-09-23 Fundacio Centre De Recerca En Sanitat Animal Polinucleotidos de haemophilus parasuis y su uso.
CA2926004A1 (en) 2006-08-11 2008-02-14 Life Sciences Research Partners Vzw Immunogenic peptides and their use in allergic and autoimmune disorders
WO2009101205A2 (en) 2008-02-14 2009-08-20 Life Sciences Research Partners Vzw Immunogenic control of tumours and tumour cells
ES2637812T3 (es) 2008-02-14 2017-10-17 Life Sciences Research Partners Vzw Inmunoterapia dirigida a patógenos intracelulares
EP3763729B1 (en) 2010-11-25 2022-07-06 Imcyse SA Immunogenic peptides for use in the prevention and/or treatment of infectious diseases, autoimmune diseases, immune responses to allofactors, allergic diseases, tumors, graft rejection and immune responses against viral vectors used for gene therapy or gene vaccination
GB201201511D0 (en) 2012-01-30 2012-03-14 Univ Leuven Kath Modified epitopes for boosting CD4+ T-cell responses
EP2860188B1 (en) * 2012-06-11 2020-10-21 Xiamen University Polypeptides and antibodies for treating hbv infection and related diseases
GB201309469D0 (en) 2013-05-28 2013-07-10 Imcyse Sa Detection of CD4+ T lymphocytes
US10729791B2 (en) 2015-05-18 2020-08-04 Imcyse Sa Animal models for evaluating pharmaceutical compounds
EP3352782B1 (en) 2015-09-25 2021-03-31 ImCyse SA Improved methods and compounds for eliminating immune responses to therapeutic agents
KR20220132023A (ko) 2016-04-19 2022-09-29 임시스 에스에이 신규 면역원성 CD1d 결합 펩티드
CN108456686B (zh) 2017-02-17 2021-03-05 厦门大学 一种用于展示目的多肽的多肽载体及其用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA792485B (en) * 1978-06-07 1980-06-25 New York Blood Center Inc Vaccine for active immunization containing hepatitis b surface and/or e-antigens
FR2480779B2 (fr) * 1979-08-30 1986-07-18 Anvar Vecteur contenant une sequence nucleotidique de l'antigene de surface du virus de l'hepatite b et procede de fabrication d'une molecule immunogene mettant en oeuvre ce vecteur
JP2530801B2 (ja) * 1978-12-22 1996-09-04 バイオゲン インコーポレイテッド 組換えdna分子
US4415491A (en) * 1980-01-14 1983-11-15 The Regents Of The University Of California Synthetic vaccine peptide epitomes of hepatitis B surface antigen
IL63224A (en) * 1980-07-17 1985-05-31 Scripps Clinic Res Synthetic peptide specific antigenic determinant and method of manufacturing antigenic materials therefrom
IL61904A (en) * 1981-01-13 1985-07-31 Yeda Res & Dev Synthetic vaccine against influenza virus infections comprising a synthetic peptide and process for producing same
DE3275998D1 (en) * 1981-12-22 1987-05-14 Baylor College Medicine Immunological composition and method for hepatitis b virus
US4483793A (en) * 1982-10-04 1984-11-20 The Regents Of The University Of California Dimeric oligopeptides as heptenic epitopic sites for hepatitis
JPS5974985A (ja) * 1982-10-19 1984-04-27 Takeda Chem Ind Ltd 新規dna
NZ207394A (en) * 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids

Also Published As

Publication number Publication date
AU4115985A (en) 1985-10-11
ATE82135T1 (de) 1992-11-15
IL90035A0 (en) 1989-12-15
AU2682388A (en) 1989-05-25
AU579148B2 (en) 1988-11-17
EP0155146A3 (en) 1988-01-20
FI854396A0 (fi) 1985-11-07
IL90035A (en) 1990-11-05
NO167359B (no) 1991-07-22
IL74545A (en) 1990-11-05
NO854460L (no) 1986-01-08
DK516385D0 (da) 1985-11-08
FI84558C (fi) 1991-12-27
NO167359C (no) 1991-10-30
CA1253069A (en) 1989-04-25
FI84558B (fi) 1991-09-13
DK516385A (da) 1985-11-08
DE3586801D1 (de) 1992-12-17
NZ227731A (en) 1990-07-26
EP0155146B1 (en) 1992-11-11
WO1985004103A1 (en) 1985-09-26
AU623106B2 (en) 1992-05-07
IL74545A0 (en) 1985-06-30
EP0155146A2 (en) 1985-09-18
NZ211356A (en) 1990-07-26

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Owner name: SCRIPPS CLINIC AND RESEARCH FOUNDATION