IL72831A - (5r,6s)-2-aminomethyl-penem compounds,their preparation and pharmaceutical compositions containing them - Google Patents

(5r,6s)-2-aminomethyl-penem compounds,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL72831A
IL72831A IL72831A IL7283184A IL72831A IL 72831 A IL72831 A IL 72831A IL 72831 A IL72831 A IL 72831A IL 7283184 A IL7283184 A IL 7283184A IL 72831 A IL72831 A IL 72831A
Authority
IL
Israel
Prior art keywords
aminomethyl
preparation
pharmaceutical compositions
compositions containing
penem compounds
Prior art date
Application number
IL72831A
Other languages
English (en)
Other versions
IL72831A0 (en
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH2510/84A external-priority patent/CH662119A5/de
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of IL72831A0 publication Critical patent/IL72831A0/xx
Publication of IL72831A publication Critical patent/IL72831A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568—Four-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL72831A 1983-09-02 1984-08-31 (5r,6s)-2-aminomethyl-penem compounds,their preparation and pharmaceutical compositions containing them IL72831A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH483183 1983-09-02
CH2510/84A CH662119A5 (en) 1984-05-22 1984-05-22 Aminomethyl-penem compounds

Publications (2)

Publication Number Publication Date
IL72831A0 IL72831A0 (en) 1984-11-30
IL72831A true IL72831A (en) 1987-12-31

Family

ID=25690638

Family Applications (1)

Application Number Title Priority Date Filing Date
IL72831A IL72831A (en) 1983-09-02 1984-08-31 (5r,6s)-2-aminomethyl-penem compounds,their preparation and pharmaceutical compositions containing them

Country Status (20)

Country Link
US (1) US4656165A (da)
AT (1) ATA279784A (da)
AU (1) AU3264484A (da)
BE (1) BE900477A (da)
DD (1) DD222314A5 (da)
DE (1) DE3431980A1 (da)
DK (1) DK419084A (da)
ES (3) ES8701763A1 (da)
FI (1) FI843427A (da)
FR (1) FR2551441A1 (da)
GB (2) GB2146021B (da)
GR (1) GR80270B (da)
HU (1) HU193054B (da)
IL (1) IL72831A (da)
IT (1) IT1177980B (da)
LU (1) LU85519A1 (da)
NL (1) NL8402668A (da)
NO (2) NO843469L (da)
PT (1) PT79143B (da)
SE (1) SE8404297L (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0042026B1 (de) * 1978-02-02 1986-01-08 Ciba-Geigy Ag 3,4-Disubstituierte Azetidin-2-onverbindungen und Verfahren zu ihrer Herstellung
US4761408A (en) * 1984-11-02 1988-08-02 Ciba-Geigy Corporation Crystalline aminomethyl compound
US5215997A (en) * 1985-09-11 1993-06-01 Ciba-Geigy Corporation Synthesis of beta-lactam compounds
ATE93861T1 (de) * 1985-09-11 1993-09-15 Ciba Geigy Ag Synthese von beta-lactamverbindungen.
EP0290385B1 (de) 1987-05-04 1992-10-21 Ciba-Geigy Ag Neues Verfahren zur Herstellung von 4-Acyloxy-3-hydroxyethyl-azetidinonen
EP0597401A3 (en) * 1992-11-11 1995-07-26 Takeda Chemical Industries Ltd Preparation of penemes.

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
EP0042026B1 (de) * 1978-02-02 1986-01-08 Ciba-Geigy Ag 3,4-Disubstituierte Azetidin-2-onverbindungen und Verfahren zu ihrer Herstellung
JPS5625110A (en) * 1978-12-18 1981-03-10 Bristol Myers Co Antibacterial
US4272437A (en) * 1978-12-18 1981-06-09 Bristol-Myers Company Antibacterial agents, and 4-thio azetidinone intermediates
GR73623B (da) * 1979-02-24 1984-03-26 Erba Farmitalia
US4386030A (en) * 1979-12-31 1983-05-31 Merck & Co., Inc. Process for preparing 6-(1'-hydroxyethyl)-2-substituted-pen-2-em-3-carboxylic acid
JPS56166194A (en) * 1980-05-27 1981-12-21 Sankyo Co Ltd Penem derivative and its preparation
US4347183A (en) * 1981-02-02 1982-08-31 Schering Corporation Process for the synthesis of penems and carbapenems
JPS588084A (ja) * 1981-07-08 1983-01-18 Takeda Chem Ind Ltd （６ｒ）−置換−（５ｒ）−ペネム−３−カルボン酸誘導体およびその製造法
DE3277696D1 (en) * 1981-07-15 1987-12-23 Sumitomo Pharma Carboxylic beta-lactam compounds and the preparation thereof
DE3366926D1 (en) * 1982-11-16 1986-11-20 Schering Corp Penems, pharmaceutical compositions containing them, process for preparing them

Also Published As

Publication number Publication date
PT79143A (en) 1984-09-01
ES8704953A1 (es) 1987-04-16
FR2551441A1 (fr) 1985-03-08
IT8448789A0 (it) 1984-08-31
ES549384A0 (es) 1987-04-16
DK419084D0 (da) 1984-08-31
PT79143B (en) 1986-11-14
SE8404297D0 (sv) 1984-08-29
GB8625937D0 (en) 1986-12-03
IT1177980B (it) 1987-09-03
IL72831A0 (en) 1984-11-30
GB2183230B (en) 1988-01-13
ES535582A0 (es) 1986-12-01
LU85519A1 (de) 1985-04-24
US4656165A (en) 1987-04-07
DD222314A5 (de) 1985-05-15
GB2146021A (en) 1985-04-11
NO843469L (no) 1985-03-04
ES549383A0 (es) 1987-04-16
NL8402668A (nl) 1985-04-01
HU193054B (en) 1987-08-28
IT8448789A1 (it) 1986-03-03
ATA279784A (de) 1987-08-15
GB2146021B (en) 1988-01-13
GB8421773D0 (en) 1984-10-03
HUT34983A (en) 1985-05-28
GB2183230A (en) 1987-06-03
AU3264484A (en) 1985-03-07
ES8704954A1 (es) 1987-04-16
FI843427A (fi) 1985-03-03
GR80270B (en) 1985-01-02
SE8404297L (sv) 1985-03-03
DK419084A (da) 1985-03-03
ES8701763A1 (es) 1986-12-01
BE900477A (fr) 1985-02-28
FI843427A0 (fi) 1984-08-31
DE3431980A1 (de) 1985-04-18
NO850932L (no) 1985-03-04

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Legal Events

Date Code Title Description
HC Change of name of proprietor(s)
KB Patent renewed
KB Patent renewed
EXP Patent expired