IL71656A - 8-substituted 4s-6-fluoro-spiro(chroman-4,4'imidazolidine)-2',5'-diones - Google Patents
8-substituted 4s-6-fluoro-spiro(chroman-4,4'imidazolidine)-2',5'-dionesInfo
- Publication number
- IL71656A IL71656A IL71656A IL7165684A IL71656A IL 71656 A IL71656 A IL 71656A IL 71656 A IL71656 A IL 71656A IL 7165684 A IL7165684 A IL 7165684A IL 71656 A IL71656 A IL 71656A
- Authority
- IL
- Israel
- Prior art keywords
- diones
- chroman
- imidazolidine
- spiro
- fluoro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/488,947 US4474967A (en) | 1983-04-27 | 1983-04-27 | 8-Deutero and 8-tritio-substituted derivatives of D-4S-6-fluoro-spiro-[chroman-4,4'-imidazolidine]-2',5'-dione |
Publications (2)
Publication Number | Publication Date |
---|---|
IL71656A0 IL71656A0 (en) | 1984-07-31 |
IL71656A true IL71656A (en) | 1987-10-20 |
Family
ID=23941785
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL71656A IL71656A (en) | 1983-04-27 | 1984-04-26 | 8-substituted 4s-6-fluoro-spiro(chroman-4,4'imidazolidine)-2',5'-diones |
Country Status (22)
Country | Link |
---|---|
US (1) | US4474967A (ru) |
EP (1) | EP0124327A3 (ru) |
JP (1) | JPS59205384A (ru) |
KR (1) | KR860000915B1 (ru) |
AU (1) | AU542142B2 (ru) |
CA (1) | CA1226866A (ru) |
CS (1) | CS250661B2 (ru) |
DD (1) | DD219772A5 (ru) |
DK (1) | DK208284A (ru) |
ES (1) | ES8607312A1 (ru) |
FI (1) | FI841657A (ru) |
GR (1) | GR81491B (ru) |
HU (1) | HU191755B (ru) |
IL (1) | IL71656A (ru) |
NO (1) | NO841627L (ru) |
NZ (1) | NZ207959A (ru) |
PH (1) | PH22869A (ru) |
PL (1) | PL142759B1 (ru) |
PT (1) | PT78476B (ru) |
SU (1) | SU1240362A3 (ru) |
YU (1) | YU43358B (ru) |
ZA (1) | ZA843091B (ru) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0172719B1 (en) * | 1984-08-20 | 1988-09-21 | Pfizer Inc. | Process for the production as asymmetric hydantoins |
US4841079A (en) * | 1987-08-07 | 1989-06-20 | Pfizer, Inc. | Process for the production of asymmetric hydantoins |
US5059693A (en) * | 1989-10-06 | 1991-10-22 | Pfizer Inc. | Process for making 3-aroyl-2-oxindole-1-carboxamides |
GB9317764D0 (en) * | 1993-08-26 | 1993-10-13 | Pfizer Ltd | Therapeutic compound |
ZA99733B (en) * | 1998-01-30 | 1999-08-02 | R Tech Ueno Ltd | Ophthalmic composition. |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3821383A (en) * | 1972-07-10 | 1974-06-28 | Ayerst Mckenna & Harrison | Compositions for and a method of treating diabetic complications |
CA1088945A (en) * | 1976-10-18 | 1980-11-04 | Pfizer Limited | Hydantoin derivatives as therapeutic agents |
US4117230A (en) * | 1976-10-18 | 1978-09-26 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
US4130714A (en) * | 1977-05-23 | 1978-12-19 | Pfizer Inc. | Hydantoin therapeutic agents |
US4248882A (en) * | 1980-02-12 | 1981-02-03 | Pfizer Inc. | Treating diabetes-associated complications with hydantoin amines |
JPS5745185A (en) * | 1980-07-21 | 1982-03-13 | Eisai Co Ltd | Hydantoin derivative and its preparation |
-
1983
- 1983-04-27 US US06/488,947 patent/US4474967A/en not_active Expired - Fee Related
-
1984
- 1984-04-19 EP EP84302667A patent/EP0124327A3/en not_active Withdrawn
- 1984-04-24 PL PL1984247379A patent/PL142759B1/pl unknown
- 1984-04-24 PT PT78476A patent/PT78476B/pt unknown
- 1984-04-24 DD DD84262257A patent/DD219772A5/de not_active IP Right Cessation
- 1984-04-25 CA CA000452774A patent/CA1226866A/en not_active Expired
- 1984-04-25 NO NO841627A patent/NO841627L/no unknown
- 1984-04-25 SU SU843732823A patent/SU1240362A3/ru active
- 1984-04-25 ES ES531873A patent/ES8607312A1/es not_active Expired
- 1984-04-26 DK DK208284A patent/DK208284A/da not_active Application Discontinuation
- 1984-04-26 NZ NZ207959A patent/NZ207959A/en unknown
- 1984-04-26 ZA ZA843091A patent/ZA843091B/xx unknown
- 1984-04-26 YU YU741/84A patent/YU43358B/xx unknown
- 1984-04-26 KR KR1019840002240A patent/KR860000915B1/ko active IP Right Grant
- 1984-04-26 PH PH30605A patent/PH22869A/en unknown
- 1984-04-26 AU AU27263/84A patent/AU542142B2/en not_active Ceased
- 1984-04-26 FI FI841657A patent/FI841657A/fi not_active Application Discontinuation
- 1984-04-26 IL IL71656A patent/IL71656A/xx not_active IP Right Cessation
- 1984-04-26 GR GR74517A patent/GR81491B/el unknown
- 1984-04-26 HU HU841622A patent/HU191755B/hu not_active IP Right Cessation
- 1984-04-26 CS CS843101A patent/CS250661B2/cs unknown
- 1984-04-27 JP JP59086040A patent/JPS59205384A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
PL142759B1 (en) | 1987-11-30 |
JPS59205384A (ja) | 1984-11-20 |
NZ207959A (en) | 1987-04-30 |
NO841627L (no) | 1984-10-29 |
EP0124327A3 (en) | 1985-07-31 |
AU542142B2 (en) | 1985-02-07 |
DK208284A (da) | 1984-10-28 |
DD219772A5 (de) | 1985-03-13 |
FI841657A0 (fi) | 1984-04-26 |
SU1240362A3 (ru) | 1986-06-23 |
YU74184A (en) | 1986-10-31 |
PT78476B (en) | 1986-08-28 |
ES8607312A1 (es) | 1986-06-01 |
DK208284D0 (da) | 1984-04-26 |
ZA843091B (en) | 1985-12-24 |
GR81491B (ru) | 1984-12-11 |
ES531873A0 (es) | 1986-06-01 |
YU43358B (en) | 1989-06-30 |
AU2726384A (en) | 1984-11-01 |
EP0124327A2 (en) | 1984-11-07 |
KR840008355A (ko) | 1984-12-14 |
US4474967A (en) | 1984-10-02 |
PH22869A (en) | 1989-01-19 |
HUT34197A (en) | 1985-02-28 |
IL71656A0 (en) | 1984-07-31 |
PT78476A (en) | 1984-05-01 |
FI841657A (fi) | 1984-10-28 |
KR860000915B1 (ko) | 1986-07-18 |
CS250661B2 (en) | 1987-05-14 |
CA1226866A (en) | 1987-09-15 |
HU191755B (en) | 1987-04-28 |
PL247379A1 (en) | 1985-03-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM9K | Patent not in force due to non-payment of renewal fees |