IL70766A - Lipopeptides,their manufacture and pharmaceutical compositions containing them - Google Patents
Lipopeptides,their manufacture and pharmaceutical compositions containing themInfo
- Publication number
- IL70766A IL70766A IL70766A IL7076684A IL70766A IL 70766 A IL70766 A IL 70766A IL 70766 A IL70766 A IL 70766A IL 7076684 A IL7076684 A IL 7076684A IL 70766 A IL70766 A IL 70766A
- Authority
- IL
- Israel
- Prior art keywords
- amino
- alpha
- acids
- radical
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
- C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH39883 | 1983-01-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL70766A0 IL70766A0 (en) | 1984-04-30 |
IL70766A true IL70766A (en) | 1987-08-31 |
Family
ID=4186110
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL70766A IL70766A (en) | 1983-01-25 | 1984-01-24 | Lipopeptides,their manufacture and pharmaceutical compositions containing them |
Country Status (18)
Country | Link |
---|---|
US (1) | US4666886A (fr) |
EP (1) | EP0114787B1 (fr) |
JP (1) | JPH068316B2 (fr) |
AT (1) | ATE67769T1 (fr) |
AU (1) | AU569865B2 (fr) |
CA (1) | CA1247089A (fr) |
DD (1) | DD213917A5 (fr) |
DE (1) | DE3485094D1 (fr) |
DK (1) | DK31684A (fr) |
ES (3) | ES8606398A1 (fr) |
FI (1) | FI83524C (fr) |
GR (1) | GR81710B (fr) |
HU (1) | HU192864B (fr) |
IE (1) | IE57092B1 (fr) |
IL (1) | IL70766A (fr) |
NZ (1) | NZ206923A (fr) |
PT (1) | PT78002B (fr) |
ZA (1) | ZA84521B (fr) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1986004334A1 (fr) * | 1985-01-18 | 1986-07-31 | MERCK Patent Gesellschaft mit beschränkter Haftung | Peptides de regulation immunitaire |
US6024964A (en) * | 1985-06-24 | 2000-02-15 | Hoechst Aktiengesellschaft | Membrane anchor/active compound conjugate, its preparation and its uses |
US6074650A (en) * | 1985-06-24 | 2000-06-13 | Hoechst Aktiengesellschaft | Membrane anchor/active compound conjugate, its preparation and its uses |
DE3546150A1 (de) | 1985-06-24 | 1987-01-22 | Hoechst Ag | Membrananker-wirkstoffkonjugat, seine herstellung sowie seine verwendung |
DE3522638A1 (de) * | 1985-06-25 | 1987-01-08 | Diamalt Ag | Neue somatostatin-derivate |
GB8524001D0 (en) * | 1985-09-30 | 1985-11-06 | Glaxo Group Ltd | Pharmaceutical composition |
US5374426A (en) * | 1986-09-03 | 1994-12-20 | University Of Saskatchewan | Rotavirus nucleocapsid protein VP6 in vaccine compositions |
CA1315465C (fr) * | 1987-07-31 | 1993-03-30 | Hans-Helmut Goertz | Polymeres de sels d'ammonium oxyalkyles insatures, leur preparation et leur utilisation |
CA2017507C (fr) * | 1989-05-25 | 1996-11-12 | Gary Van Nest | Adjuvant constitue d'une emulsion de gouttelettes submicron d'huile |
DE4119856A1 (de) * | 1991-06-17 | 1992-12-24 | Hoechst Ag | N-acyl-s-(2-hydroxyalkyl)-cysteine, deren herstellung sowie deren verwendung als zwischenprodukte zur herstellung von synthetischen immunadjuvantien und synthetischen impfstoffen |
SG47406A1 (en) * | 1991-12-19 | 1998-04-17 | Ciba Geigy Ag | Aminosulfonic acid derivatives and processes for their preparation |
AU666789B2 (en) * | 1992-12-28 | 1996-02-22 | Takeda Chemical Industries Ltd. | 2-amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, production and use thereof |
EP0604945A1 (fr) * | 1992-12-28 | 1994-07-06 | Takeda Chemical Industries, Ltd. | TAN-1511, dérivés, préparation et utilisation |
EP0641776A3 (fr) * | 1993-09-08 | 1997-05-02 | Takeda Chemical Industries Ltd | Dérivés de thioglycérol. |
WO1996040213A1 (fr) * | 1995-06-07 | 1996-12-19 | Cytel Corporation | Production et purification de peptides |
CA2235245A1 (fr) * | 1995-10-17 | 1997-04-24 | Dovetail Technologies, Inc | Stimulants a faible poids moleculaire des cellules de la moelle osseuse et du systeme immunitaire |
GB9614871D0 (en) | 1996-07-15 | 1996-09-04 | Smithkline Beecham Plc | Compounds |
DE69803653T2 (de) * | 1997-12-05 | 2002-08-29 | F. Hoffmann-La Roche Ag, Basel | 1,3,8-Triazaspiro[4,5]decan-4-on-derivate |
GB0016811D0 (en) * | 2000-07-07 | 2000-08-30 | Adprotech Ltd | Lipid rafts |
FR2816060A1 (fr) * | 2000-10-27 | 2002-05-03 | Pf Medicament | Procede d'identification de nouvelles molecules se liant au recepteur lox et utilisation de ces molecules |
EP1671981A3 (fr) * | 2000-10-27 | 2006-07-05 | Chiron SRL. | Acides nucléiques et protéines de streptocoque, groupe A |
US7082569B2 (en) | 2001-01-17 | 2006-07-25 | Outlooksoft Corporation | Systems and methods providing dynamic spreadsheet functionality |
MX2008001183A (es) * | 2005-07-25 | 2008-04-11 | Therimunex Llc | Peptidil diacilgliceridos. |
WO2007099650A1 (fr) * | 2006-03-01 | 2007-09-07 | Fukuoka Prefectural Government | Vecteur contenant un lipide peptidique et procede permettant d'introduire un compose dans des cellules l'utilisant |
US20080051603A1 (en) * | 2006-06-15 | 2008-02-28 | Cell Therapeutics, Inc. | Process for the preparation of poly-alpha-glutamic acid and derivatives thereof |
PT2411521E (pt) | 2009-03-25 | 2015-04-21 | Univ Texas | Composições para estimulação de resistência imunitária inata de mamíferos contra patogénicos |
KR101080271B1 (ko) * | 2009-03-31 | 2011-11-08 | 주식회사 웰스킨 | 다이펩타이드를 유효성분으로 포함하는 자외선에 의한 홍반반응 억제용 화장품 조성물 |
CA2766907A1 (fr) | 2009-07-06 | 2011-01-13 | Novartis Ag | Molecules d'arn autorepliquantes et leurs utilisations |
EP4218799A1 (fr) | 2009-07-15 | 2023-08-02 | GlaxoSmithKline Biologicals S.A. | Compositions de protéine f rsv et leurs procédés de fabrication |
DE102009034779A1 (de) * | 2009-07-25 | 2011-02-03 | Emc Microcollections Gmbh | Synthetische Analoga bakterieller Lipopeptide und ihre Anwendung zur Therapie und Prophylaxe allergischer Erkrankungen |
ES2443952T3 (es) | 2009-09-02 | 2014-02-21 | Novartis Ag | Composiciones inmunógenas que incluyen moduladores de la actividad de TLR |
EA023725B1 (ru) * | 2010-03-23 | 2016-07-29 | Новартис Аг | Соединения (липопептиды на основе цистеина) и композиции в качестве агонистов tlr2, применяемые для лечения инфекционных, воспалительных, респираторных и других заболеваний |
EP2575988A1 (fr) | 2010-05-28 | 2013-04-10 | Tetris Online, Inc. | Infrastructure de jeu informatique asynchrone hybride interactif |
MX2013000163A (es) | 2010-07-06 | 2013-03-05 | Novartis Ag | Metodos y composiciones inmunogenicas derivadas de norovirus. |
US9192661B2 (en) | 2010-07-06 | 2015-11-24 | Novartis Ag | Delivery of self-replicating RNA using biodegradable polymer particles |
NZ608362A (en) | 2010-09-01 | 2015-11-27 | Novartis Ag | Adsorption of immunopotentiators to insoluble metal salts |
EP2667892B1 (fr) | 2011-01-26 | 2019-03-27 | GlaxoSmithKline Biologicals SA | Régime d'immunisation contre le vrs |
AU2012222883A1 (en) | 2011-03-02 | 2013-10-17 | Novartis Ag | Combination vaccines with lower doses of antigen and/or adjuvant |
WO2012129483A1 (fr) * | 2011-03-24 | 2012-09-27 | Novartis Ag | Nanoémulsions adjuvantes avec des phospholipides |
PT2707385T (pt) | 2011-05-13 | 2017-12-19 | Glaxosmithkline Biologicals Sa | Antigénios de f de rsv pré-fusão |
MX2014002363A (es) | 2011-09-01 | 2014-04-14 | Novartis Ag | Formulaciones de antigenos de staphylococcus aureus con adyuvante. |
NL2007536C2 (en) * | 2011-10-05 | 2013-04-08 | Academisch Ziekenhuis Leiden Lumc | Adjuvant compound. |
JP2015510872A (ja) | 2012-03-07 | 2015-04-13 | ノバルティス アーゲー | Streptococcuspneumoniae抗原の増強された製剤 |
CN104582726A (zh) | 2012-03-07 | 2015-04-29 | 诺华股份有限公司 | 狂犬病病毒免疫原的含佐剂制剂 |
RU2014140521A (ru) | 2012-03-08 | 2016-04-27 | Новартис Аг | Адъювантные составы бустерных вакцин |
EP2659908A1 (fr) | 2012-05-01 | 2013-11-06 | Affiris AG | Compositions |
EP2659907A1 (fr) | 2012-05-01 | 2013-11-06 | Affiris AG | Compositions |
EP2659906A1 (fr) | 2012-05-01 | 2013-11-06 | Affiris AG | Compositions |
RU2015106930A (ru) | 2012-09-06 | 2016-10-20 | Новартис Аг | Комбинированные вакцины с менингококком серогруппы в и к/д/с |
JP6440619B2 (ja) | 2012-10-12 | 2018-12-19 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 混合ワクチン用の架橋されていない無細胞百日咳抗原 |
WO2014118305A1 (fr) | 2013-02-01 | 2014-08-07 | Novartis Ag | Administration intradermique de compositions immunologiques comprenant des agonistes des récepteurs de type toll |
KR20160030097A (ko) | 2013-05-10 | 2016-03-16 | 노파르티스 아게 | 인플루엔자 백신에서 기면증 위험의 방지 |
ES2769647T3 (es) | 2014-03-26 | 2020-06-26 | Glaxosmithkline Biologicals Sa | Antígenos estafilocócicos mutantes |
WO2016044839A2 (fr) | 2014-09-19 | 2016-03-24 | The Board Of Regents Of The University Of Texas System | Compositions et méthodes pour traiter des infections virales par le biais de l'immunité innée stimulée en combinaison avec des composés antiviraux |
EP3302536A1 (fr) | 2015-06-03 | 2018-04-11 | Affiris AG | Vaccins d'il-23-p19 |
AU2016289497A1 (en) | 2015-07-07 | 2017-12-07 | Affiris Ag | Vaccines for the treatment and prevention of IgE mediated diseases |
DE102016005550A1 (de) | 2016-05-09 | 2017-11-09 | Emc Microcollections Gmbh | Adjuvans zur lnduzierung einer zellulären lmmunantwort |
WO2018183827A1 (fr) * | 2017-03-31 | 2018-10-04 | Temple University-Of The Commonwealth System Of Higher Education | Transformateur différentiel variable flexible |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0000330B1 (fr) * | 1977-06-20 | 1981-08-05 | Ciba-Geigy Ag | Lipopeptides, procédé pour leur préparation et compositions pharmaceutiques les contenant |
HU186585B (en) * | 1978-05-18 | 1985-08-28 | Ciba Geigy Ag | Process for producing new muramil-peptide derivatives |
EP0014815A3 (fr) * | 1978-12-20 | 1980-10-29 | Ciba-Geigy Ag | Dérivés peptidiques, procédé pour leur préparation et intermédiaires, et compositions pharmaceutiques contenant un de ces composés |
FR2460288A1 (fr) * | 1979-06-29 | 1981-01-23 | Rhone Poulenc Ind | Nouveaux dipeptides, leur preparation et les medicaments qui les contiennent |
FR2460290A1 (fr) * | 1979-06-29 | 1981-01-23 | Rhone Poulenc Ind | Nouveaux tetra- ou pentapeptides, leur preparation et les medicaments qui les contiennent |
-
1984
- 1984-01-19 DE DE8484810030T patent/DE3485094D1/de not_active Expired - Lifetime
- 1984-01-19 EP EP84810030A patent/EP0114787B1/fr not_active Expired - Lifetime
- 1984-01-19 AT AT84810030T patent/ATE67769T1/de not_active IP Right Cessation
- 1984-01-23 FI FI840259A patent/FI83524C/fi not_active IP Right Cessation
- 1984-01-23 GR GR73573A patent/GR81710B/el unknown
- 1984-01-23 CA CA000445858A patent/CA1247089A/fr not_active Expired
- 1984-01-23 HU HU84264A patent/HU192864B/hu not_active IP Right Cessation
- 1984-01-23 ES ES529091A patent/ES8606398A1/es not_active Expired
- 1984-01-23 DD DD84259549A patent/DD213917A5/de not_active IP Right Cessation
- 1984-01-24 DK DK31684A patent/DK31684A/da unknown
- 1984-01-24 IL IL70766A patent/IL70766A/xx not_active IP Right Cessation
- 1984-01-24 IE IE157/84A patent/IE57092B1/en not_active IP Right Cessation
- 1984-01-24 NZ NZ206923A patent/NZ206923A/en unknown
- 1984-01-24 PT PT78002A patent/PT78002B/pt not_active IP Right Cessation
- 1984-01-24 AU AU23745/84A patent/AU569865B2/en not_active Ceased
- 1984-01-24 ZA ZA84521A patent/ZA84521B/xx unknown
- 1984-01-25 JP JP59010362A patent/JPH068316B2/ja not_active Expired - Lifetime
-
1985
- 1985-06-14 ES ES544193A patent/ES8802620A1/es not_active Expired
- 1985-06-14 ES ES544194A patent/ES8606393A1/es not_active Expired
- 1985-07-17 US US06/756,146 patent/US4666886A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
FI840259A (fi) | 1984-07-26 |
DD213917A5 (de) | 1984-09-26 |
EP0114787A3 (en) | 1987-05-06 |
EP0114787A2 (fr) | 1984-08-01 |
ES544194A0 (es) | 1986-04-01 |
AU569865B2 (en) | 1988-02-25 |
ES8606393A1 (es) | 1986-04-01 |
JPH068316B2 (ja) | 1994-02-02 |
IE840157L (en) | 1984-07-25 |
ZA84521B (en) | 1984-09-26 |
PT78002B (en) | 1986-06-18 |
AU2374584A (en) | 1984-07-26 |
FI840259A0 (fi) | 1984-01-23 |
DK31684A (da) | 1984-07-26 |
IE57092B1 (en) | 1992-04-22 |
ES529091A0 (es) | 1986-04-01 |
GR81710B (fr) | 1984-12-12 |
FI83524C (fi) | 1991-07-25 |
DK31684D0 (da) | 1984-01-24 |
US4666886A (en) | 1987-05-19 |
ATE67769T1 (de) | 1991-10-15 |
ES544193A0 (es) | 1988-09-16 |
ES8606398A1 (es) | 1986-04-01 |
EP0114787B1 (fr) | 1991-09-25 |
IL70766A0 (en) | 1984-04-30 |
NZ206923A (en) | 1988-05-30 |
JPS59139348A (ja) | 1984-08-10 |
DE3485094D1 (de) | 1991-10-31 |
CA1247089A (fr) | 1988-12-20 |
HU192864B (en) | 1987-07-28 |
ES8802620A1 (es) | 1988-09-16 |
PT78002A (en) | 1984-02-01 |
FI83524B (fi) | 1991-04-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RH | Patent void |