IL70757A - 3-morpholinoethylamino-6-cyclohexyl-or-thienylpyridazine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
3-morpholinoethylamino-6-cyclohexyl-or-thienylpyridazine derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL70757A IL70757A IL70757A IL7075784A IL70757A IL 70757 A IL70757 A IL 70757A IL 70757 A IL70757 A IL 70757A IL 7075784 A IL7075784 A IL 7075784A IL 70757 A IL70757 A IL 70757A
- Authority
- IL
- Israel
- Prior art keywords
- derivatives
- cyclohexyl
- thienylpyridazine
- morpholinoethylamino
- preparation
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 2
- 125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000001541 3-thienyl group Chemical group S1C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000004892 pyridazines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8301029A FR2539742B1 (fr) | 1983-01-24 | 1983-01-24 | Derives amines de la pyridazine substitues en position 6 par un heterocycle ou un alicycle, lesdits derives etant actifs sur le systeme nerveux central |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL70757A0 IL70757A0 (en) | 1984-04-30 |
| IL70757A true IL70757A (en) | 1986-12-31 |
Family
ID=9285222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL70757A IL70757A (en) | 1983-01-24 | 1984-01-23 | 3-morpholinoethylamino-6-cyclohexyl-or-thienylpyridazine derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4524070A (cs) |
| EP (1) | EP0117171B1 (cs) |
| JP (1) | JPS59139367A (cs) |
| KR (1) | KR910000641B1 (cs) |
| AT (1) | ATE28077T1 (cs) |
| AU (1) | AU560542B2 (cs) |
| CA (1) | CA1218063A (cs) |
| CS (1) | CS241539B2 (cs) |
| DD (1) | DD238793A5 (cs) |
| DE (1) | DE3464491D1 (cs) |
| DK (1) | DK31584A (cs) |
| ES (1) | ES529007A0 (cs) |
| FI (1) | FI840268A7 (cs) |
| FR (1) | FR2539742B1 (cs) |
| GR (1) | GR81717B (cs) |
| HU (1) | HU192390B (cs) |
| IE (1) | IE840150L (cs) |
| IL (1) | IL70757A (cs) |
| NO (1) | NO840244L (cs) |
| NZ (1) | NZ206907A (cs) |
| PT (1) | PT77982B (cs) |
| SU (1) | SU1189345A3 (cs) |
| YU (1) | YU12384A (cs) |
| ZA (1) | ZA84501B (cs) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5141628A (en) * | 1987-08-19 | 1992-08-25 | Rwe-Entsorgung Aktiengesellschaft | Method of cleaning and regenerating used oils |
| US5656631A (en) * | 1989-02-07 | 1997-08-12 | Sanofi | Pyridazine derivatives |
| FR2665442B1 (fr) * | 1990-07-31 | 1992-12-04 | Sanofi Sa | Derives d'alkyl-6 pyridazine, procede de preparation et compositions pharmaceutiques en contenant. |
| US5461053A (en) * | 1989-02-07 | 1995-10-24 | Sanofi | Pyridazine derivatives |
| PT93060B (pt) | 1989-02-07 | 1995-12-29 | Sanofi Sa | Processo para a obtencao de derivados de piridazina e de composicoes farmaceuticas que os contem |
| AU2005260102A1 (en) * | 2004-05-08 | 2006-01-12 | Novartis International Pharmaceutical Ltd. | 3-aryl-5,6-disubstituted pyridazines |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1292443A (en) * | 1968-11-01 | 1972-10-11 | Ct D Etudes Experimentales Et | New pyridazine derivatives and process for their preparation |
| GB1345880A (en) * | 1971-06-18 | 1974-02-06 | Cepbepe | Pyridazine derivatives |
-
1983
- 1983-01-24 FR FR8301029A patent/FR2539742B1/fr not_active Expired
-
1984
- 1984-01-18 AT AT84400102T patent/ATE28077T1/de active
- 1984-01-18 EP EP84400102A patent/EP0117171B1/fr not_active Expired
- 1984-01-18 US US06/571,698 patent/US4524070A/en not_active Expired - Fee Related
- 1984-01-18 DE DE8484400102T patent/DE3464491D1/de not_active Expired
- 1984-01-18 CA CA000445483A patent/CA1218063A/en not_active Expired
- 1984-01-19 ES ES529007A patent/ES529007A0/es active Granted
- 1984-01-20 NZ NZ206907A patent/NZ206907A/en unknown
- 1984-01-20 PT PT77982A patent/PT77982B/pt not_active IP Right Cessation
- 1984-01-23 SU SU843694357A patent/SU1189345A3/ru active
- 1984-01-23 KR KR1019840000274A patent/KR910000641B1/ko not_active Expired
- 1984-01-23 FI FI840268A patent/FI840268A7/fi not_active Application Discontinuation
- 1984-01-23 GR GR73585A patent/GR81717B/el unknown
- 1984-01-23 ZA ZA84501A patent/ZA84501B/xx unknown
- 1984-01-23 IL IL70757A patent/IL70757A/xx unknown
- 1984-01-23 NO NO840244A patent/NO840244L/no unknown
- 1984-01-23 IE IE840150A patent/IE840150L/xx unknown
- 1984-01-23 DD DD84259545A patent/DD238793A5/de unknown
- 1984-01-24 JP JP59010903A patent/JPS59139367A/ja active Pending
- 1984-01-24 CS CS84530A patent/CS241539B2/cs unknown
- 1984-01-24 YU YU00123/84A patent/YU12384A/xx unknown
- 1984-01-24 AU AU23727/84A patent/AU560542B2/en not_active Ceased
- 1984-01-24 DK DK31584A patent/DK31584A/da unknown
- 1984-01-24 HU HU84294A patent/HU192390B/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE840150L (en) | 1984-07-24 |
| PT77982B (fr) | 1986-04-10 |
| NZ206907A (en) | 1987-03-31 |
| KR840007409A (ko) | 1984-12-07 |
| HU192390B (en) | 1987-06-29 |
| CS53084A2 (en) | 1985-07-16 |
| NO840244L (no) | 1984-07-25 |
| EP0117171B1 (fr) | 1987-07-01 |
| IL70757A0 (en) | 1984-04-30 |
| ZA84501B (en) | 1984-09-26 |
| KR910000641B1 (ko) | 1991-01-31 |
| FI840268A0 (fi) | 1984-01-23 |
| DK31584A (da) | 1984-07-25 |
| ES8407043A1 (es) | 1984-09-01 |
| CA1218063A (en) | 1987-02-17 |
| DK31584D0 (da) | 1984-01-24 |
| EP0117171A1 (fr) | 1984-08-29 |
| DE3464491D1 (en) | 1987-08-06 |
| FI840268A7 (fi) | 1984-07-25 |
| GR81717B (cs) | 1984-12-12 |
| ATE28077T1 (de) | 1987-07-15 |
| US4524070A (en) | 1985-06-18 |
| SU1189345A3 (ru) | 1985-10-30 |
| AU560542B2 (en) | 1987-04-09 |
| YU12384A (en) | 1986-10-31 |
| DD238793A5 (de) | 1986-09-03 |
| PT77982A (fr) | 1984-02-01 |
| AU2372784A (en) | 1984-07-26 |
| JPS59139367A (ja) | 1984-08-10 |
| FR2539742A1 (fr) | 1984-07-27 |
| FR2539742B1 (fr) | 1986-09-05 |
| CS241539B2 (en) | 1986-03-13 |
| ES529007A0 (es) | 1984-09-01 |
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