IL68832A - Pharmaceutical compositions containing(+)-cyanidan-3-ol derivatives,certain such novel compounds and their manufacture - Google Patents

Pharmaceutical compositions containing(+)-cyanidan-3-ol derivatives,certain such novel compounds and their manufacture

Info

Publication number
IL68832A
IL68832A IL68832A IL6883283A IL68832A IL 68832 A IL68832 A IL 68832A IL 68832 A IL68832 A IL 68832A IL 6883283 A IL6883283 A IL 6883283A IL 68832 A IL68832 A IL 68832A
Authority
IL
Israel
Prior art keywords
sub
unsubstituted
substituted
cyanidan
derivatives
Prior art date
Application number
IL68832A
Other languages
English (en)
Other versions
IL68832A0 (en
Original Assignee
Zyma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zyma Sa filed Critical Zyma Sa
Publication of IL68832A0 publication Critical patent/IL68832A0/xx
Publication of IL68832A publication Critical patent/IL68832A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pyrane Compounds (AREA)
IL68832A 1982-06-01 1983-05-31 Pharmaceutical compositions containing(+)-cyanidan-3-ol derivatives,certain such novel compounds and their manufacture IL68832A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8215867 1982-06-01

Publications (2)

Publication Number Publication Date
IL68832A0 IL68832A0 (en) 1983-09-30
IL68832A true IL68832A (en) 1988-06-30

Family

ID=10530750

Family Applications (1)

Application Number Title Priority Date Filing Date
IL68832A IL68832A (en) 1982-06-01 1983-05-31 Pharmaceutical compositions containing(+)-cyanidan-3-ol derivatives,certain such novel compounds and their manufacture

Country Status (19)

Country Link
US (1) US4644011A (ja)
EP (1) EP0096007B1 (ja)
JP (1) JPS58219177A (ja)
KR (1) KR840005124A (ja)
AT (1) ATE28641T1 (ja)
AU (1) AU568301B2 (ja)
CA (1) CA1234103A (ja)
DD (1) DD210687A5 (ja)
DE (1) DE3372764D1 (ja)
DK (1) DK245283A (ja)
ES (2) ES522814A0 (ja)
FI (1) FI831926L (ja)
GB (1) GB2122608B (ja)
GR (1) GR78346B (ja)
IL (1) IL68832A (ja)
NO (1) NO831950L (ja)
NZ (1) NZ204422A (ja)
PT (1) PT76782B (ja)
ZA (1) ZA833908B (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5141745A (en) * 1986-03-27 1992-08-25 The Lubrizol Corporation Nodulation inducing factors
US4743694A (en) * 1986-04-11 1988-05-10 Mercek & Co., Inc. Diastereocontrolled synthesis of 2-amino alcohols
AU601992B2 (en) * 1986-06-21 1990-09-27 Dainippon Ink And Chemicals Inc. Isoliquiritigenin for the treatment of kidney and liver diseases
US6207842B1 (en) 1997-10-09 2001-03-27 Mars Incorporated Process for preparing procyanidin(4-6 or 4-8) oligomers and their derivatives
US6156912A (en) * 1999-04-09 2000-12-05 Mars, Incorporated 88, 66, and 68 catechin and epicatechin dimers and methods for their preparation
US7015338B1 (en) 1999-04-15 2006-03-21 Mars Incorporated Synthetic methods for preparing procyanidin oligomers
NL1016815C2 (nl) * 1999-12-15 2002-05-14 Ciba Sc Holding Ag Oximester-fotoinitiatoren.
US6476241B1 (en) * 2000-09-05 2002-11-05 Mars Incorporated Synthesis of 4α-arylepicatechins
US7067679B2 (en) * 2002-10-02 2006-06-27 Mars, Inc. Synthesis of dimeric, trimeric, tetrameric pentameric, and higher oligomeric epicatechin-derived procyanidins having 4,8-interflavan linkages and their use to inhibit cancer cell growth through cell cycle arrest
US20070004796A1 (en) * 2005-06-29 2007-01-04 Romanczyk Leo Jr Processes for the preparation of protected-(+)-catechin and (-)-epicatechin monomers, for coupling the protected monomers with an activated, protected epicatechin monomer, and for the preparation of epicatechin-(4B,8)-epicatechin or -catechin dimers and their digallates
ES2635507T3 (es) * 2010-04-12 2017-10-04 Berkem S.A. Procedimiento para la fabricación de derivados de polifenoles estabilizados
ES2636441T3 (es) * 2011-01-27 2017-10-05 Sphaera Pharma Pte. Ltd Un procedimiento novedoso para la síntesis de polifenoles
CN106518802B (zh) * 2016-11-17 2018-11-09 山东铂源药业有限公司 一种2-(3-醛基-4-羟基苯基)-4-甲基噻唑-5-甲酸乙酯的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1575004A (en) * 1976-03-23 1980-09-17 Iverni Della Beffa Spa Pharmacologically active polyphenolic substances
US4255336A (en) * 1977-11-25 1981-03-10 Ciba-Geigy Corporation Process for the preparation of O-substituted derivatives of (+)-cyanidan-3-01
EP0037800B1 (de) * 1980-04-03 1987-08-12 Zyma SA Verwendung von O-substituierten Derivaten von (+)-Cyanidanol-3 als Verbindungen mit immunomodulatorischen Eigenschaften

Also Published As

Publication number Publication date
FI831926A0 (fi) 1983-05-30
EP0096007A3 (en) 1984-01-04
ES536423A0 (es) 1987-04-16
DE3372764D1 (en) 1987-09-03
DK245283D0 (da) 1983-05-31
CA1234103A (en) 1988-03-15
JPS58219177A (ja) 1983-12-20
KR840005124A (ko) 1984-11-03
EP0096007A2 (en) 1983-12-07
AU568301B2 (en) 1987-12-24
ES8704919A1 (es) 1987-04-16
GB8312765D0 (en) 1983-06-15
PT76782A (en) 1983-06-01
DD210687A5 (de) 1984-06-20
NO831950L (no) 1983-12-02
ZA833908B (en) 1984-01-25
GR78346B (ja) 1984-09-26
EP0096007B1 (en) 1987-07-29
FI831926L (fi) 1983-12-02
AU1525583A (en) 1983-12-08
ATE28641T1 (de) 1987-08-15
DK245283A (da) 1983-12-02
GB2122608A (en) 1984-01-18
IL68832A0 (en) 1983-09-30
PT76782B (en) 1986-05-20
ES8507533A1 (es) 1985-09-16
NZ204422A (en) 1986-09-10
GB2122608B (en) 1985-10-02
US4644011A (en) 1987-02-17
ES522814A0 (es) 1985-09-16

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