ES522814A0 - Procedimiento para preparar derivados (+)-cianidan-3-ol. - Google Patents
Procedimiento para preparar derivados (+)-cianidan-3-ol.Info
- Publication number
- ES522814A0 ES522814A0 ES522814A ES522814A ES522814A0 ES 522814 A0 ES522814 A0 ES 522814A0 ES 522814 A ES522814 A ES 522814A ES 522814 A ES522814 A ES 522814A ES 522814 A0 ES522814 A0 ES 522814A0
- Authority
- ES
- Spain
- Prior art keywords
- sub
- unsubstituted
- substituted
- free
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
- C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8215867 | 1982-06-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8507533A1 ES8507533A1 (es) | 1985-09-16 |
| ES522814A0 true ES522814A0 (es) | 1985-09-16 |
Family
ID=10530750
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES522814A Granted ES522814A0 (es) | 1982-06-01 | 1983-05-30 | Procedimiento para preparar derivados (+)-cianidan-3-ol. |
| ES536423A Expired ES8704919A1 (es) | 1982-06-01 | 1984-10-01 | Procedimiento para preparar derivados de (+)-cianidan-3-ol |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES536423A Expired ES8704919A1 (es) | 1982-06-01 | 1984-10-01 | Procedimiento para preparar derivados de (+)-cianidan-3-ol |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4644011A (es) |
| EP (1) | EP0096007B1 (es) |
| JP (1) | JPS58219177A (es) |
| KR (1) | KR840005124A (es) |
| AT (1) | ATE28641T1 (es) |
| AU (1) | AU568301B2 (es) |
| CA (1) | CA1234103A (es) |
| DD (1) | DD210687A5 (es) |
| DE (1) | DE3372764D1 (es) |
| DK (1) | DK245283A (es) |
| ES (2) | ES522814A0 (es) |
| FI (1) | FI831926L (es) |
| GB (1) | GB2122608B (es) |
| GR (1) | GR78346B (es) |
| IL (1) | IL68832A (es) |
| NO (1) | NO831950L (es) |
| NZ (1) | NZ204422A (es) |
| PT (1) | PT76782B (es) |
| ZA (1) | ZA833908B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5141745A (en) * | 1986-03-27 | 1992-08-25 | The Lubrizol Corporation | Nodulation inducing factors |
| US4743694A (en) * | 1986-04-11 | 1988-05-10 | Mercek & Co., Inc. | Diastereocontrolled synthesis of 2-amino alcohols |
| US4898890A (en) * | 1986-06-21 | 1990-02-06 | Dainippon Ink And Chemicals, Inc. | Medicines for use in the therapy and prevention of kidney and liver diseases |
| US6207842B1 (en) | 1997-10-09 | 2001-03-27 | Mars Incorporated | Process for preparing procyanidin(4-6 or 4-8) oligomers and their derivatives |
| US6156912A (en) * | 1999-04-09 | 2000-12-05 | Mars, Incorporated | 88, 66, and 68 catechin and epicatechin dimers and methods for their preparation |
| US7015338B1 (en) | 1999-04-15 | 2006-03-21 | Mars Incorporated | Synthetic methods for preparing procyanidin oligomers |
| NL1016815C2 (nl) * | 1999-12-15 | 2002-05-14 | Ciba Sc Holding Ag | Oximester-fotoinitiatoren. |
| US6476241B1 (en) * | 2000-09-05 | 2002-11-05 | Mars Incorporated | Synthesis of 4α-arylepicatechins |
| US7067679B2 (en) * | 2002-10-02 | 2006-06-27 | Mars, Inc. | Synthesis of dimeric, trimeric, tetrameric pentameric, and higher oligomeric epicatechin-derived procyanidins having 4,8-interflavan linkages and their use to inhibit cancer cell growth through cell cycle arrest |
| US20070004796A1 (en) * | 2005-06-29 | 2007-01-04 | Romanczyk Leo Jr | Processes for the preparation of protected-(+)-catechin and (-)-epicatechin monomers, for coupling the protected monomers with an activated, protected epicatechin monomer, and for the preparation of epicatechin-(4B,8)-epicatechin or -catechin dimers and their digallates |
| ES2635507T3 (es) * | 2010-04-12 | 2017-10-04 | Berkem S.A. | Procedimiento para la fabricación de derivados de polifenoles estabilizados |
| US9428482B2 (en) | 2011-01-27 | 2016-08-30 | Sphaera Pharma Pte. Ltd. | Process for synthesis of polyphenols |
| CN106518802B (zh) * | 2016-11-17 | 2018-11-09 | 山东铂源药业有限公司 | 一种2-(3-醛基-4-羟基苯基)-4-甲基噻唑-5-甲酸乙酯的合成方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1575004A (en) * | 1976-03-23 | 1980-09-17 | Iverni Della Beffa Spa | Pharmacologically active polyphenolic substances |
| US4255336A (en) * | 1977-11-25 | 1981-03-10 | Ciba-Geigy Corporation | Process for the preparation of O-substituted derivatives of (+)-cyanidan-3-01 |
| EP0037800B1 (de) * | 1980-04-03 | 1987-08-12 | Zyma SA | Verwendung von O-substituierten Derivaten von (+)-Cyanidanol-3 als Verbindungen mit immunomodulatorischen Eigenschaften |
-
1983
- 1983-05-10 GB GB08312765A patent/GB2122608B/en not_active Expired
- 1983-05-26 DE DE8383810222T patent/DE3372764D1/de not_active Expired
- 1983-05-26 EP EP83810222A patent/EP0096007B1/en not_active Expired
- 1983-05-26 AT AT83810222T patent/ATE28641T1/de not_active IP Right Cessation
- 1983-05-30 ES ES522814A patent/ES522814A0/es active Granted
- 1983-05-30 CA CA000429160A patent/CA1234103A/en not_active Expired
- 1983-05-30 ZA ZA833908A patent/ZA833908B/xx unknown
- 1983-05-30 GR GR71509A patent/GR78346B/el unknown
- 1983-05-30 FI FI831926A patent/FI831926L/fi not_active Application Discontinuation
- 1983-05-31 NO NO831950A patent/NO831950L/no unknown
- 1983-05-31 PT PT76782A patent/PT76782B/pt unknown
- 1983-05-31 KR KR1019830002400A patent/KR840005124A/ko not_active Application Discontinuation
- 1983-05-31 AU AU15255/83A patent/AU568301B2/en not_active Ceased
- 1983-05-31 IL IL68832A patent/IL68832A/xx unknown
- 1983-05-31 JP JP58096840A patent/JPS58219177A/ja active Pending
- 1983-05-31 DD DD83251542A patent/DD210687A5/de not_active IP Right Cessation
- 1983-05-31 NZ NZ204422A patent/NZ204422A/en unknown
- 1983-05-31 DK DK245283A patent/DK245283A/da not_active Application Discontinuation
-
1984
- 1984-10-01 ES ES536423A patent/ES8704919A1/es not_active Expired
-
1985
- 1985-07-09 US US06/754,181 patent/US4644011A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU568301B2 (en) | 1987-12-24 |
| AU1525583A (en) | 1983-12-08 |
| GB2122608A (en) | 1984-01-18 |
| ES8507533A1 (es) | 1985-09-16 |
| EP0096007B1 (en) | 1987-07-29 |
| IL68832A (en) | 1988-06-30 |
| IL68832A0 (en) | 1983-09-30 |
| EP0096007A2 (en) | 1983-12-07 |
| JPS58219177A (ja) | 1983-12-20 |
| US4644011A (en) | 1987-02-17 |
| GB8312765D0 (en) | 1983-06-15 |
| DK245283A (da) | 1983-12-02 |
| GR78346B (es) | 1984-09-26 |
| NO831950L (no) | 1983-12-02 |
| ZA833908B (en) | 1984-01-25 |
| DE3372764D1 (en) | 1987-09-03 |
| FI831926L (fi) | 1983-12-02 |
| GB2122608B (en) | 1985-10-02 |
| ATE28641T1 (de) | 1987-08-15 |
| CA1234103A (en) | 1988-03-15 |
| PT76782A (en) | 1983-06-01 |
| KR840005124A (ko) | 1984-11-03 |
| DK245283D0 (da) | 1983-05-31 |
| DD210687A5 (de) | 1984-06-20 |
| ES8704919A1 (es) | 1987-04-16 |
| FI831926A0 (fi) | 1983-05-30 |
| ES536423A0 (es) | 1987-04-16 |
| PT76782B (en) | 1986-05-20 |
| EP0096007A3 (en) | 1984-01-04 |
| NZ204422A (en) | 1986-09-10 |
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