DK245283D0 - Fremgangsmade til fremstilling af (+)-cyanidan-3-ol-derivater - Google Patents

Fremgangsmade til fremstilling af (+)-cyanidan-3-ol-derivater

Info

Publication number
DK245283D0
DK245283D0 DK2452/83A DK245283A DK245283D0 DK 245283 D0 DK245283 D0 DK 245283D0 DK 2452/83 A DK2452/83 A DK 2452/83A DK 245283 A DK245283 A DK 245283A DK 245283 D0 DK245283 D0 DK 245283D0
Authority
DK
Denmark
Prior art keywords
sub
unsubstituted
substituted
free
hydrogen
Prior art date
Application number
DK2452/83A
Other languages
English (en)
Other versions
DK245283A (da
Inventor
Marc Ernest Ballenegger
Christian Gerard Rimbault
Alban Imre Albert
Andre Jean Weith
Pierre Courbat
Robert Graham Tyson
Derek Reginald Palmer
David George Thompson
Original Assignee
Zyma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zyma Sa filed Critical Zyma Sa
Publication of DK245283D0 publication Critical patent/DK245283D0/da
Publication of DK245283A publication Critical patent/DK245283A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/74Benzo[b]pyrans, hydrogenated in the carbocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36Compounds containing methylenedioxyphenyl groups, e.g. sesamin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • C07D311/62Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pyrane Compounds (AREA)
DK245283A 1982-06-01 1983-05-31 Fremgangsmaade til fremstilling af (+)-cyanidan-3-ol-derivater DK245283A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8215867 1982-06-01

Publications (2)

Publication Number Publication Date
DK245283D0 true DK245283D0 (da) 1983-05-31
DK245283A DK245283A (da) 1983-12-02

Family

ID=10530750

Family Applications (1)

Application Number Title Priority Date Filing Date
DK245283A DK245283A (da) 1982-06-01 1983-05-31 Fremgangsmaade til fremstilling af (+)-cyanidan-3-ol-derivater

Country Status (19)

Country Link
US (1) US4644011A (da)
EP (1) EP0096007B1 (da)
JP (1) JPS58219177A (da)
KR (1) KR840005124A (da)
AT (1) ATE28641T1 (da)
AU (1) AU568301B2 (da)
CA (1) CA1234103A (da)
DD (1) DD210687A5 (da)
DE (1) DE3372764D1 (da)
DK (1) DK245283A (da)
ES (2) ES522814A0 (da)
FI (1) FI831926L (da)
GB (1) GB2122608B (da)
GR (1) GR78346B (da)
IL (1) IL68832A (da)
NO (1) NO831950L (da)
NZ (1) NZ204422A (da)
PT (1) PT76782B (da)
ZA (1) ZA833908B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5141745A (en) * 1986-03-27 1992-08-25 The Lubrizol Corporation Nodulation inducing factors
US4743694A (en) * 1986-04-11 1988-05-10 Mercek & Co., Inc. Diastereocontrolled synthesis of 2-amino alcohols
AU601992B2 (en) * 1986-06-21 1990-09-27 Dainippon Ink And Chemicals Inc. Isoliquiritigenin for the treatment of kidney and liver diseases
US6207842B1 (en) 1997-10-09 2001-03-27 Mars Incorporated Process for preparing procyanidin(4-6 or 4-8) oligomers and their derivatives
US6156912A (en) * 1999-04-09 2000-12-05 Mars, Incorporated 88, 66, and 68 catechin and epicatechin dimers and methods for their preparation
US7015338B1 (en) 1999-04-15 2006-03-21 Mars Incorporated Synthetic methods for preparing procyanidin oligomers
NL1016815C2 (nl) * 1999-12-15 2002-05-14 Ciba Sc Holding Ag Oximester-fotoinitiatoren.
US6476241B1 (en) * 2000-09-05 2002-11-05 Mars Incorporated Synthesis of 4α-arylepicatechins
US7067679B2 (en) * 2002-10-02 2006-06-27 Mars, Inc. Synthesis of dimeric, trimeric, tetrameric pentameric, and higher oligomeric epicatechin-derived procyanidins having 4,8-interflavan linkages and their use to inhibit cancer cell growth through cell cycle arrest
US20070004796A1 (en) * 2005-06-29 2007-01-04 Romanczyk Leo Jr Processes for the preparation of protected-(+)-catechin and (-)-epicatechin monomers, for coupling the protected monomers with an activated, protected epicatechin monomer, and for the preparation of epicatechin-(4B,8)-epicatechin or -catechin dimers and their digallates
ES2635507T3 (es) * 2010-04-12 2017-10-04 Berkem S.A. Procedimiento para la fabricación de derivados de polifenoles estabilizados
ES2636441T3 (es) * 2011-01-27 2017-10-05 Sphaera Pharma Pte. Ltd Un procedimiento novedoso para la síntesis de polifenoles
CN106518802B (zh) * 2016-11-17 2018-11-09 山东铂源药业有限公司 一种2-(3-醛基-4-羟基苯基)-4-甲基噻唑-5-甲酸乙酯的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1575004A (en) * 1976-03-23 1980-09-17 Iverni Della Beffa Spa Pharmacologically active polyphenolic substances
US4255336A (en) * 1977-11-25 1981-03-10 Ciba-Geigy Corporation Process for the preparation of O-substituted derivatives of (+)-cyanidan-3-01
EP0037800B1 (de) * 1980-04-03 1987-08-12 Zyma SA Verwendung von O-substituierten Derivaten von (+)-Cyanidanol-3 als Verbindungen mit immunomodulatorischen Eigenschaften

Also Published As

Publication number Publication date
FI831926A0 (fi) 1983-05-30
EP0096007A3 (en) 1984-01-04
ES536423A0 (es) 1987-04-16
DE3372764D1 (en) 1987-09-03
CA1234103A (en) 1988-03-15
JPS58219177A (ja) 1983-12-20
KR840005124A (ko) 1984-11-03
EP0096007A2 (en) 1983-12-07
AU568301B2 (en) 1987-12-24
IL68832A (en) 1988-06-30
ES8704919A1 (es) 1987-04-16
GB8312765D0 (en) 1983-06-15
PT76782A (en) 1983-06-01
DD210687A5 (de) 1984-06-20
NO831950L (no) 1983-12-02
ZA833908B (en) 1984-01-25
GR78346B (da) 1984-09-26
EP0096007B1 (en) 1987-07-29
FI831926L (fi) 1983-12-02
AU1525583A (en) 1983-12-08
ATE28641T1 (de) 1987-08-15
DK245283A (da) 1983-12-02
GB2122608A (en) 1984-01-18
IL68832A0 (en) 1983-09-30
PT76782B (en) 1986-05-20
ES8507533A1 (es) 1985-09-16
NZ204422A (en) 1986-09-10
GB2122608B (en) 1985-10-02
US4644011A (en) 1987-02-17
ES522814A0 (es) 1985-09-16

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment