IL68152A0 - Improvements in or relating to thiazole anti-ulcer drugs - Google Patents

Improvements in or relating to thiazole anti-ulcer drugs

Info

Publication number
IL68152A0
IL68152A0 IL68152A IL6815283A IL68152A0 IL 68152 A0 IL68152 A0 IL 68152A0 IL 68152 A IL68152 A IL 68152A IL 6815283 A IL6815283 A IL 6815283A IL 68152 A0 IL68152 A0 IL 68152A0
Authority
IL
Israel
Prior art keywords
sub
sup
alkyl
aryl
alkynyl
Prior art date
Application number
IL68152A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL68152A0 publication Critical patent/IL68152A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/194—Radicals derived from thio- or thiono carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Supply Devices, Intensifiers, Converters, And Telemotors (AREA)
  • Earth Drilling (AREA)
  • Inert Electrodes (AREA)
  • Treating Waste Gases (AREA)
IL68152A 1982-03-19 1983-03-16 Improvements in or relating to thiazole anti-ulcer drugs IL68152A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/360,034 US4474794A (en) 1982-03-19 1982-03-19 N-Thiazolylmethylthioalkyl-N1 -alkenyl (or alkynyl)guanidines and related compounds

Publications (1)

Publication Number Publication Date
IL68152A0 true IL68152A0 (en) 1983-06-15

Family

ID=23416322

Family Applications (1)

Application Number Title Priority Date Filing Date
IL68152A IL68152A0 (en) 1982-03-19 1983-03-16 Improvements in or relating to thiazole anti-ulcer drugs

Country Status (22)

Country Link
US (1) US4474794A (ja)
EP (1) EP0091220B1 (ja)
JP (1) JPS58170773A (ja)
KR (1) KR840004091A (ja)
AT (1) ATE27156T1 (ja)
AU (1) AU1254583A (ja)
CA (1) CA1190547A (ja)
CS (1) CS236788B2 (ja)
DD (1) DD207376A5 (ja)
DE (1) DE3371514D1 (ja)
DK (1) DK91083A (ja)
ES (1) ES520791A0 (ja)
FI (1) FI830879L (ja)
GB (1) GB2116973B (ja)
GR (1) GR77882B (ja)
IL (1) IL68152A0 (ja)
NZ (1) NZ203605A (ja)
PH (1) PH18504A (ja)
PL (1) PL241066A1 (ja)
PT (1) PT76397B (ja)
RO (1) RO85385B (ja)
ZA (1) ZA831882B (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1277325C (en) * 1985-12-18 1990-12-04 Bruce A. Slomski Synthesis of nizatidine
ATE86619T1 (de) * 1987-04-06 1993-03-15 Heumann Pharma Gmbh & Co Verfahren zur herstellung von nitroethenderivaten.
NL9000132A (nl) * 1990-01-19 1991-08-16 Cedona Pharm Bv Nieuwe thiazoolderivaten.
US20230349922A1 (en) 2020-08-11 2023-11-02 Université De Strasbourg H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200578A (en) * 1978-12-18 1980-04-29 Bristol-Myers Company Thiazole derivatives
US4375547A (en) * 1980-10-02 1983-03-01 Eli Lilly And Company N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine

Also Published As

Publication number Publication date
PL241066A1 (en) 1985-01-02
EP0091220A2 (en) 1983-10-12
GB2116973B (en) 1985-08-29
AU1254583A (en) 1983-09-22
KR840004091A (ko) 1984-10-06
GB2116973A (en) 1983-10-05
CA1190547A (en) 1985-07-16
JPS58170773A (ja) 1983-10-07
FI830879L (fi) 1983-09-20
DK91083D0 (da) 1983-02-25
ATE27156T1 (de) 1987-05-15
PT76397A (en) 1983-04-01
PT76397B (en) 1986-02-04
FI830879A0 (fi) 1983-03-16
ZA831882B (en) 1984-11-28
EP0091220B1 (en) 1987-05-13
ES8405386A1 (es) 1984-06-01
PH18504A (en) 1985-08-02
DD207376A5 (de) 1984-02-29
EP0091220A3 (en) 1984-05-23
DK91083A (da) 1983-09-20
CS236788B2 (en) 1985-05-15
GR77882B (ja) 1984-09-25
RO85385A (ro) 1984-11-25
GB8307201D0 (en) 1983-04-20
NZ203605A (en) 1985-10-11
DE3371514D1 (en) 1987-06-19
US4474794A (en) 1984-10-02
RO85385B (ro) 1984-11-30
ES520791A0 (es) 1984-06-01

Similar Documents

Publication Publication Date Title
KR830007624A (ko) 헤테로 사이클릭 화합물의 제조방법
ES8605511A1 (es) Un procedimiento para la preparacion de derivados de tiazol,2, 4, disustituidos.
KR940005633A (ko) 약제학적으로 유용한 항경련제 설파메이트의 이미데이트 유도체
JPS5622770A (en) Amidine derivative and its preparation
ES8301950A1 (es) Un procedimiento para la preparacion de un derivado de tia- zol
ES383868A1 (es) Un procedimiento de preparar oxindolcarboxamidas.
EP0125803A3 (en) Pharmaceutically active dihydropyridines
GB2116973B (en) Improvements in or relating to thiazole anti-ulcer drugs
KR900018042A (ko) 부텐산 유도체
JPS6438091A (en) Condensed heterocyclic sulfonylurea
ATE27455T1 (de) Heterocyclische guanidino-phenylamidine, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung.
ES8609314A1 (es) Procedimiento pra la preparacion de 1,4-dihidropiridinas sustituidas,opticamente activas
EP0372410A3 (en) Use of heterocyclic amides to inhibit tumor metastasis
ES8201541A1 (es) Un procedimiento para la preparacion de nuevas guanilamidi- nas
ATE44741T1 (de) 2-(n-substituierte guanidino)-4heteroarylthiazole als mittel gegen geschwuere.
FI850593L (fi) N-(2,6-disubstituerade aromatiska) -n'-pyridinylureafoereningar.
ES8604531A1 (es) Procedimiento para preparar pirido(1,4)benzodiazepinas
TH68407A (th) 3-ไพริดิล-4-แอริลพิร์โรลที่ถูกแทนที่ และวิธีการรักษาโรคและการป้องกันโรคที่เกี่ยวข้อง
TH630A (th) N-(อาริลไธโออัลคิล)-n'-(อมิโนอัลคิล)ยูเรีย
TH3061A (th) 2-(อัลคอกซิมิโนอัลคอกซีคาร์บอนิล)-เฟนนิลซัลโฟนิลซัลโฟนิลยูเรีย
NO912420L (no) Antiatherosklerotiske og antitrombotiske 1-benzopyran-4-oner og 2-amino-1,3-benzoksazin-4-oner.