IL67381A - N-substituted-4-aminomethyl-imidazole derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
N-substituted-4-aminomethyl-imidazole derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL67381A IL67381A IL67381A IL6738182A IL67381A IL 67381 A IL67381 A IL 67381A IL 67381 A IL67381 A IL 67381A IL 6738182 A IL6738182 A IL 6738182A IL 67381 A IL67381 A IL 67381A
- Authority
- IL
- Israel
- Prior art keywords
- sub
- hydrogen
- compounds
- carbon atoms
- substituted
- Prior art date
Links
- -1 N-substituted-4-aminomethyl-imidazole Chemical class 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229940079865 intestinal antiinfectives imidazole derivative Drugs 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 6
- 239000001257 hydrogen Substances 0.000 abstract 6
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 230000002785 anti-thrombosis Effects 0.000 abstract 1
- 239000003146 anticoagulant agent Substances 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB08136646A GB2110663B (en) | 1981-12-04 | 1981-12-04 | Imidazole derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL67381A0 IL67381A0 (en) | 1983-05-15 |
| IL67381A true IL67381A (en) | 1986-08-31 |
Family
ID=10526383
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL67381A IL67381A (en) | 1981-12-04 | 1982-12-01 | N-substituted-4-aminomethyl-imidazole derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4517198A (de) |
| EP (1) | EP0081324B1 (de) |
| JP (1) | JPS58105970A (de) |
| AT (1) | ATE21246T1 (de) |
| AU (1) | AU552908B2 (de) |
| CA (1) | CA1184183A (de) |
| DE (1) | DE3272478D1 (de) |
| DK (1) | DK157926C (de) |
| FI (1) | FI76569C (de) |
| GB (1) | GB2110663B (de) |
| IE (1) | IE54243B1 (de) |
| IL (1) | IL67381A (de) |
| NO (1) | NO158017C (de) |
| NZ (1) | NZ202649A (de) |
| ZA (1) | ZA828803B (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2548183B1 (fr) * | 1983-07-01 | 1985-10-31 | Synthelabo | Diphenylazomethines portant un radical imidazolyle, leur preparation et leur application en therapeutique |
| FR2575469B1 (fr) * | 1984-12-27 | 1987-01-23 | Synthelabo | N-imidazolylmethyl-diphenylazomethines, leur preparation et leur application en therapeutique |
| FR2575470B1 (fr) * | 1984-12-27 | 1987-02-13 | Synthelabo | Derives amines de n-imidazolylmethyl-diphenylazomethines, leur preparation et leur application en therapeutique |
| US4996221A (en) * | 1987-01-13 | 1991-02-26 | The Board Of Trustees Of The Leland Stanford Junior University | Histamine derivatives as immune modulators |
| AU627559B2 (en) * | 1989-03-30 | 1992-08-27 | Farmos-Yhtyma Oy | Novel aromatase inhibiting 4(5)-imidazoles |
| NZ238688A (en) * | 1990-06-28 | 1992-05-26 | Smithkline Beecham Corp | Substituted histidines: pharmaceutical compositions, preparation and uses thereof |
| US5159083A (en) * | 1990-12-28 | 1992-10-27 | Neurogen Corporation | Certain aminomethyl phenylimidazole derivatives; a class of dopamine receptor subtype specific ligands |
| GB9127304D0 (en) * | 1991-12-23 | 1992-02-19 | Boots Co Plc | Therapeutic agents |
| USRE37303E1 (en) * | 1992-01-10 | 2001-07-31 | Institut National Del La Sante Et De La Recherche Medicale | Imidazole compounds and their therapeutic applications |
| FR2686084B1 (fr) * | 1992-01-10 | 1995-12-22 | Bioprojet Soc Civ | Nouveaux derives de l'imidazole, leur preparation et leurs applications therapeutiques. |
| FR2689508B1 (fr) * | 1992-04-01 | 1994-06-17 | Fournier Ind & Sante | Derives de l'imidazole, leur procede de preparation et leur application en therapeutique. |
| GB9312893D0 (en) * | 1993-06-22 | 1993-08-04 | Boots Co Plc | Therapeutic agents |
| AU7275894A (en) * | 1993-08-04 | 1995-02-28 | Yamanouchi Pharmaceutical Co., Ltd. | Imidazolylalkylamine derivative and pharmaceutical composition thereof |
| US6448282B1 (en) | 1995-05-30 | 2002-09-10 | Gliatech, Inc. | 1H-4(5)-substituted imidazole derivatives |
| PT841922E (pt) * | 1995-05-30 | 2002-07-31 | Gliatech Inc | Derivados de ih-imidazole 4(5)-substituidos |
| BR0211098A (pt) * | 2001-07-11 | 2004-11-09 | Univ Yale | Compostos e métodos para a inibição de trypanosoma cruzi |
| US20030152747A1 (en) * | 2002-01-11 | 2003-08-14 | The Garland Company, Inc., An Ohio Corporation | Roofing materials |
| AU2007312390B2 (en) * | 2006-10-19 | 2013-03-28 | F. Hoffmann-La Roche Ag | Aminomethyl-4-imidazoles |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE276541C (de) * | ||||
| GB1341375A (en) * | 1969-11-19 | 1973-12-19 | Smith Kline French Lab | Aminoalkylimidazoles and process for their production |
| DE2842280A1 (de) * | 1978-09-28 | 1980-04-10 | Bayer Ag | N-(1,3-azolyl)-alkyl-halogenacetanilide, verfahren zu ihrer herstellung sowie ihre verwendung als herbizide |
| AU518569B2 (en) * | 1979-08-07 | 1981-10-08 | Farmos-Yhtyma Oy | 4-benzyl- and 4-benzoyl imidazole derivatives |
-
1981
- 1981-12-04 GB GB08136646A patent/GB2110663B/en not_active Expired
-
1982
- 1982-11-11 FI FI823871A patent/FI76569C/fi not_active IP Right Cessation
- 1982-11-25 CA CA000416315A patent/CA1184183A/en not_active Expired
- 1982-11-25 AT AT82306295T patent/ATE21246T1/de not_active IP Right Cessation
- 1982-11-25 DE DE8282306295T patent/DE3272478D1/de not_active Expired
- 1982-11-25 EP EP82306295A patent/EP0081324B1/de not_active Expired
- 1982-11-29 AU AU90957/82A patent/AU552908B2/en not_active Ceased
- 1982-11-29 NZ NZ202649A patent/NZ202649A/en unknown
- 1982-11-30 ZA ZA828803A patent/ZA828803B/xx unknown
- 1982-11-30 DK DK531282A patent/DK157926C/da not_active IP Right Cessation
- 1982-12-01 IL IL67381A patent/IL67381A/xx not_active IP Right Cessation
- 1982-12-03 JP JP57213236A patent/JPS58105970A/ja active Granted
- 1982-12-03 US US06/446,717 patent/US4517198A/en not_active Expired - Fee Related
- 1982-12-03 NO NO824062A patent/NO158017C/no unknown
- 1982-12-03 IE IE2877/82A patent/IE54243B1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0081324B1 (de) | 1986-08-06 |
| US4517198A (en) | 1985-05-14 |
| NZ202649A (en) | 1985-04-30 |
| CA1184183A (en) | 1985-03-19 |
| DK531282A (da) | 1983-06-05 |
| EP0081324A2 (de) | 1983-06-15 |
| GB2110663B (en) | 1985-08-07 |
| GB2110663A (en) | 1983-06-22 |
| EP0081324A3 (en) | 1983-12-07 |
| AU552908B2 (en) | 1986-06-26 |
| JPS58105970A (ja) | 1983-06-24 |
| DE3272478D1 (en) | 1986-09-11 |
| NO158017B (no) | 1988-03-21 |
| IE54243B1 (en) | 1989-08-02 |
| AU9095782A (en) | 1983-06-09 |
| ATE21246T1 (de) | 1986-08-15 |
| IL67381A0 (en) | 1983-05-15 |
| NO824062L (no) | 1983-06-06 |
| DK157926B (da) | 1990-03-05 |
| FI823871A0 (fi) | 1982-11-11 |
| FI76569B (fi) | 1988-07-29 |
| ZA828803B (en) | 1983-09-28 |
| JPH0344072B2 (de) | 1991-07-04 |
| IE822877L (en) | 1983-06-04 |
| FI76569C (fi) | 1988-11-10 |
| FI823871L (fi) | 1983-06-05 |
| DK157926C (da) | 1990-08-06 |
| NO158017C (no) | 1988-06-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU537028B2 (en) | Imidazole derivatives | |
| GB2110663B (en) | Imidazole derivatives | |
| GB2092569B (en) | Substituted imidazole derivatives and their preparation and use | |
| ATE87473T1 (de) | Arzneimittel zur inhibition von hautfalte. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |