IL67180A0 - Morphinate derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
Morphinate derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL67180A0 IL67180A0 IL67180A IL6718082A IL67180A0 IL 67180 A0 IL67180 A0 IL 67180A0 IL 67180 A IL67180 A IL 67180A IL 6718082 A IL6718082 A IL 6718082A IL 67180 A0 IL67180 A0 IL 67180A0
- Authority
- IL
- Israel
- Prior art keywords
- morphinate
- derivatives
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/28—Morphinans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/319,482 US4374139A (en) | 1981-11-09 | 1981-11-09 | Levorotatory N-substituted acylmorphinans useful as analgesic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL67180A0 true IL67180A0 (en) | 1983-03-31 |
Family
ID=23242421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL67180A IL67180A0 (en) | 1981-11-09 | 1982-11-05 | Morphinate derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4374139A (cs) |
| EP (1) | EP0079556A3 (cs) |
| JP (1) | JPS5888364A (cs) |
| KR (1) | KR840002357A (cs) |
| AU (1) | AU9027682A (cs) |
| CA (1) | CA1195324A (cs) |
| DK (1) | DK491582A (cs) |
| ES (2) | ES8500948A1 (cs) |
| FI (1) | FI823824L (cs) |
| GR (1) | GR78317B (cs) |
| HU (1) | HU187425B (cs) |
| IL (1) | IL67180A0 (cs) |
| MC (1) | MC1490A1 (cs) |
| NO (1) | NO823707L (cs) |
| NZ (1) | NZ202404A (cs) |
| PH (1) | PH18458A (cs) |
| PT (1) | PT75815B (cs) |
| ZA (1) | ZA827905B (cs) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4423221A (en) * | 1982-06-10 | 1983-12-27 | Sisa Pharmaceutical Laboratories, Inc. | 7-Carboethoxy-morphinan-6-one compounds |
| US4454141A (en) * | 1982-09-23 | 1984-06-12 | Sisa Pharmaceutical Laboratories, Inc. | Trans-B/C-7-(1-hydroxypentyl)-3-methoxy-17 methyl-6,7-didehydromorphinans, and methods of relieving pain with them |
| EP0184041A1 (en) * | 1984-11-13 | 1986-06-11 | Miles Inc. | 6-Methylene morphinan purification technique |
| US4929622A (en) * | 1987-09-24 | 1990-05-29 | Hoechst-Roussel Pharmaceuticals, Inc. | 2,6-Methanopyrrolo-3-benzazocines |
| DE4304450A1 (de) * | 1993-02-13 | 1994-08-18 | Boehringer Mannheim Gmbh | System zur Zubereitung von Flüssigkeiten |
| ES2572332T3 (es) | 2000-10-31 | 2016-05-31 | Rensselaer Polytech Inst | 2,6-metano-3-benzazocinas sustituidas en posición 8 y morfinanos sustituidos en posición 3 como ligandos de receptores opioides |
| EP1554572B1 (en) | 2001-07-25 | 2009-10-14 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| US20040204862A1 (en) * | 2003-04-11 | 2004-10-14 | Wainer Irving W. | Computer-based model for identification and characterization for non-competitive inhibitors of nicotinic acetylcholine receptors and related ligand-gated ion channel receptors |
| CN102379684B (zh) | 2005-04-28 | 2014-11-19 | 普罗透斯数字保健公司 | 药物信息系统 |
| US8795627B2 (en) | 2007-03-21 | 2014-08-05 | Raptor Pharmaceuticals Inc. | Treatment of liver disorders by administration of RAP conjugates |
| CN102316902B (zh) | 2009-02-20 | 2014-09-24 | to-BBB控股股份有限公司 | 基于谷胱甘肽的药物递送系统 |
| IL295075A (en) | 2009-05-06 | 2022-09-01 | Laboratory Skin Care Inc | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same |
| EP3569234A1 (en) | 2009-12-04 | 2019-11-20 | Alkermes Pharma Ireland Limited | Morphinan derivatives for the treatment of drug overdose |
| CA2793725C (en) | 2010-03-22 | 2018-05-01 | Rensselaer Polytechnic Institute | Carboxamide bioisosteres of opiates |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
| PT2725908T (pt) | 2011-06-29 | 2017-08-31 | Alkermes Inc | Compostos opioides de ação periférica |
| US9211293B2 (en) | 2011-12-15 | 2015-12-15 | Alkermes Pharma Ireland Limited | Opioid agonist antagonist combinations |
| WO2014190271A2 (en) | 2013-05-24 | 2014-11-27 | Alkermes Pharma Ireland Limted | Methods for treating depressive symptoms |
| CA2911231C (en) | 2013-05-24 | 2021-12-07 | Alkermes Pharma Ireland Limited | Morphan and morphinan analogues, and methods of use |
| US10745402B2 (en) | 2017-01-02 | 2020-08-18 | Purdue Pharma L.P. | Morphinan derivatives and use thereof |
| EP4243768A1 (en) | 2020-11-12 | 2023-09-20 | Alkermes Pharma Ireland Limited | Immediate release multilayer tablet |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3723437A (en) * | 1970-09-15 | 1973-03-27 | American Home Prod | 4,10-(methaniminomethano phenanthrene derivatives |
| ZA73988B (en) * | 1972-03-10 | 1973-10-31 | Hoffmann La Roche | Morphinan derivatives |
| US3914233A (en) * | 1972-10-20 | 1975-10-21 | Hoffmann La Roche | 4-Hydroxy-N-substituted morphinan derivatives |
-
1981
- 1981-11-09 US US06/319,482 patent/US4374139A/en not_active Expired - Fee Related
- 1981-12-29 GR GR69729A patent/GR78317B/el unknown
-
1982
- 1982-10-28 ZA ZA827905A patent/ZA827905B/xx unknown
- 1982-11-05 IL IL67180A patent/IL67180A0/xx unknown
- 1982-11-05 NZ NZ202404A patent/NZ202404A/en unknown
- 1982-11-05 DK DK491582A patent/DK491582A/da not_active Application Discontinuation
- 1982-11-08 EP EP82110285A patent/EP0079556A3/de not_active Ceased
- 1982-11-08 JP JP57194799A patent/JPS5888364A/ja active Pending
- 1982-11-08 FI FI823824A patent/FI823824L/fi not_active Application Discontinuation
- 1982-11-08 PT PT75815A patent/PT75815B/pt unknown
- 1982-11-08 CA CA000415102A patent/CA1195324A/en not_active Expired
- 1982-11-08 ES ES517222A patent/ES8500948A1/es not_active Expired
- 1982-11-08 PH PH28105A patent/PH18458A/en unknown
- 1982-11-08 NO NO823707A patent/NO823707L/no unknown
- 1982-11-08 MC MC821609A patent/MC1490A1/xx unknown
- 1982-11-08 HU HU823578A patent/HU187425B/hu unknown
- 1982-11-09 AU AU90276/82A patent/AU9027682A/en not_active Abandoned
- 1982-11-09 KR KR1019820005066A patent/KR840002357A/ko not_active Withdrawn
-
1984
- 1984-02-01 ES ES529349A patent/ES8506635A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FI823824A0 (fi) | 1982-11-08 |
| ES529349A0 (es) | 1985-08-01 |
| NZ202404A (en) | 1985-11-08 |
| PT75815B (en) | 1986-01-21 |
| ZA827905B (en) | 1983-08-31 |
| ES517222A0 (es) | 1984-12-01 |
| MC1490A1 (fr) | 1983-09-12 |
| NO823707L (no) | 1983-05-10 |
| DK491582A (da) | 1983-05-10 |
| CA1195324A (en) | 1985-10-15 |
| FI823824A7 (fi) | 1983-05-10 |
| AU9027682A (en) | 1983-05-19 |
| EP0079556A2 (de) | 1983-05-25 |
| KR840002357A (ko) | 1984-06-25 |
| US4374139A (en) | 1983-02-15 |
| ES8506635A1 (es) | 1985-08-01 |
| PT75815A (en) | 1982-12-01 |
| ES8500948A1 (es) | 1984-12-01 |
| FI823824L (fi) | 1983-05-10 |
| HU187425B (en) | 1986-01-28 |
| GR78317B (cs) | 1984-09-26 |
| JPS5888364A (ja) | 1983-05-26 |
| EP0079556A3 (de) | 1983-08-24 |
| PH18458A (en) | 1985-07-18 |
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