DK491582A - Fremgangsmaade til fremstilling af morphinanderivater - Google Patents
Fremgangsmaade til fremstilling af morphinanderivater Download PDFInfo
- Publication number
- DK491582A DK491582A DK491582A DK491582A DK491582A DK 491582 A DK491582 A DK 491582A DK 491582 A DK491582 A DK 491582A DK 491582 A DK491582 A DK 491582A DK 491582 A DK491582 A DK 491582A
- Authority
- DK
- Denmark
- Prior art keywords
- morphinand
- derivatives
- procedure
- preparation
- morphinand derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/28—Morphinans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/319,482 US4374139A (en) | 1981-11-09 | 1981-11-09 | Levorotatory N-substituted acylmorphinans useful as analgesic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK491582A true DK491582A (da) | 1983-05-10 |
Family
ID=23242421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK491582A DK491582A (da) | 1981-11-09 | 1982-11-05 | Fremgangsmaade til fremstilling af morphinanderivater |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4374139A (cs) |
| EP (1) | EP0079556A3 (cs) |
| JP (1) | JPS5888364A (cs) |
| KR (1) | KR840002357A (cs) |
| AU (1) | AU9027682A (cs) |
| CA (1) | CA1195324A (cs) |
| DK (1) | DK491582A (cs) |
| ES (2) | ES517222A0 (cs) |
| FI (1) | FI823824L (cs) |
| GR (1) | GR78317B (cs) |
| HU (1) | HU187425B (cs) |
| IL (1) | IL67180A0 (cs) |
| MC (1) | MC1490A1 (cs) |
| NO (1) | NO823707L (cs) |
| NZ (1) | NZ202404A (cs) |
| PH (1) | PH18458A (cs) |
| PT (1) | PT75815B (cs) |
| ZA (1) | ZA827905B (cs) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4423221A (en) * | 1982-06-10 | 1983-12-27 | Sisa Pharmaceutical Laboratories, Inc. | 7-Carboethoxy-morphinan-6-one compounds |
| US4454141A (en) * | 1982-09-23 | 1984-06-12 | Sisa Pharmaceutical Laboratories, Inc. | Trans-B/C-7-(1-hydroxypentyl)-3-methoxy-17 methyl-6,7-didehydromorphinans, and methods of relieving pain with them |
| EP0184041A1 (en) * | 1984-11-13 | 1986-06-11 | Miles Inc. | 6-Methylene morphinan purification technique |
| US4929622A (en) * | 1987-09-24 | 1990-05-29 | Hoechst-Roussel Pharmaceuticals, Inc. | 2,6-Methanopyrrolo-3-benzazocines |
| DE4304450A1 (de) * | 1993-02-13 | 1994-08-18 | Boehringer Mannheim Gmbh | System zur Zubereitung von Flüssigkeiten |
| WO2002036573A2 (en) * | 2000-10-31 | 2002-05-10 | Rensselaer Polytechnic Institute | 8- substituted-2, 6-methano-3-benzazocines and 3-substituted morphinanes as opioid receptor binding agents |
| US20030129186A1 (en) | 2001-07-25 | 2003-07-10 | Biomarin Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| US20040204862A1 (en) * | 2003-04-11 | 2004-10-14 | Wainer Irving W. | Computer-based model for identification and characterization for non-competitive inhibitors of nicotinic acetylcholine receptors and related ligand-gated ion channel receptors |
| EP3827747A1 (en) | 2005-04-28 | 2021-06-02 | Otsuka Pharmaceutical Co., Ltd. | Pharma-informatics system |
| US8795627B2 (en) | 2007-03-21 | 2014-08-05 | Raptor Pharmaceuticals Inc. | Treatment of liver disorders by administration of RAP conjugates |
| PT3395372T (pt) | 2009-02-20 | 2022-05-05 | Enhanx Biopharm Inc | Sistema de entrega de medicamentos à base de glutationa |
| KR101741629B1 (ko) | 2009-05-06 | 2017-05-31 | 라보라토리 스킨 케어, 인크. | 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법 |
| PT2506712T (pt) | 2009-12-04 | 2019-05-31 | Alkermes Pharma Ireland Ltd | Derivados de morfinano para o tratamento da overdose por fármaco |
| ES2582306T3 (es) | 2010-03-22 | 2016-09-12 | Rensselaer Polytechnic Institute | Derivados de morfinano que contienen un grupo carboxamida como ligandos de receptores opioides |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
| HUE034326T2 (en) | 2011-06-29 | 2018-02-28 | Alkermes Inc | Peripherally acting opioid compounds |
| US9211293B2 (en) | 2011-12-15 | 2015-12-15 | Alkermes Pharma Ireland Limited | Opioid agonist antagonist combinations |
| JP2016519161A (ja) | 2013-05-24 | 2016-06-30 | アルカームス ファーマ アイルランド リミテッド | モルファン及びモルフィナン類似物及び使用の方法 |
| US9656961B2 (en) | 2013-05-24 | 2017-05-23 | Alkermes Pharma Ireland Limited | Methods for treating depressive symptoms |
| WO2018125716A1 (en) * | 2017-01-02 | 2018-07-05 | Purdue Pharma L.P. | Morphinan derivatives and use thereof |
| WO2022101444A1 (en) | 2020-11-12 | 2022-05-19 | Alkermes Pharma Ireland Limited | Immediate release multilayer tablet |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3723437A (en) * | 1970-09-15 | 1973-03-27 | American Home Prod | 4,10-(methaniminomethano phenanthrene derivatives |
| ZA73988B (en) * | 1972-03-10 | 1973-10-31 | Hoffmann La Roche | Morphinan derivatives |
| US3914233A (en) * | 1972-10-20 | 1975-10-21 | Hoffmann La Roche | 4-Hydroxy-N-substituted morphinan derivatives |
-
1981
- 1981-11-09 US US06/319,482 patent/US4374139A/en not_active Expired - Fee Related
- 1981-12-29 GR GR69729A patent/GR78317B/el unknown
-
1982
- 1982-10-28 ZA ZA827905A patent/ZA827905B/xx unknown
- 1982-11-05 DK DK491582A patent/DK491582A/da not_active Application Discontinuation
- 1982-11-05 IL IL67180A patent/IL67180A0/xx unknown
- 1982-11-05 NZ NZ202404A patent/NZ202404A/en unknown
- 1982-11-08 HU HU823578A patent/HU187425B/hu unknown
- 1982-11-08 PT PT75815A patent/PT75815B/pt unknown
- 1982-11-08 JP JP57194799A patent/JPS5888364A/ja active Pending
- 1982-11-08 NO NO823707A patent/NO823707L/no unknown
- 1982-11-08 MC MC821609A patent/MC1490A1/xx unknown
- 1982-11-08 PH PH28105A patent/PH18458A/en unknown
- 1982-11-08 ES ES517222A patent/ES517222A0/es active Granted
- 1982-11-08 FI FI823824A patent/FI823824L/fi not_active Application Discontinuation
- 1982-11-08 CA CA000415102A patent/CA1195324A/en not_active Expired
- 1982-11-08 EP EP82110285A patent/EP0079556A3/de not_active Ceased
- 1982-11-09 KR KR1019820005066A patent/KR840002357A/ko not_active Withdrawn
- 1982-11-09 AU AU90276/82A patent/AU9027682A/en not_active Abandoned
-
1984
- 1984-02-01 ES ES529349A patent/ES529349A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| KR840002357A (ko) | 1984-06-25 |
| ES8506635A1 (es) | 1985-08-01 |
| AU9027682A (en) | 1983-05-19 |
| IL67180A0 (en) | 1983-03-31 |
| ES8500948A1 (es) | 1984-12-01 |
| FI823824A0 (fi) | 1982-11-08 |
| EP0079556A2 (de) | 1983-05-25 |
| FI823824A7 (fi) | 1983-05-10 |
| MC1490A1 (fr) | 1983-09-12 |
| NZ202404A (en) | 1985-11-08 |
| PT75815A (en) | 1982-12-01 |
| GR78317B (cs) | 1984-09-26 |
| PH18458A (en) | 1985-07-18 |
| US4374139A (en) | 1983-02-15 |
| HU187425B (en) | 1986-01-28 |
| ZA827905B (en) | 1983-08-31 |
| EP0079556A3 (de) | 1983-08-24 |
| NO823707L (no) | 1983-05-10 |
| PT75815B (en) | 1986-01-21 |
| JPS5888364A (ja) | 1983-05-26 |
| CA1195324A (en) | 1985-10-15 |
| ES529349A0 (es) | 1985-08-01 |
| ES517222A0 (es) | 1984-12-01 |
| FI823824L (fi) | 1983-05-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |