FI823824L - Morfinanderivat - Google Patents

Morfinanderivat

Info

Publication number
FI823824L
FI823824L FI823824A FI823824A FI823824L FI 823824 L FI823824 L FI 823824L FI 823824 A FI823824 A FI 823824A FI 823824 A FI823824 A FI 823824A FI 823824 L FI823824 L FI 823824L
Authority
FI
Finland
Prior art keywords
morfinanderivat
Prior art date
Application number
FI823824A
Other languages
English (en)
Finnish (fi)
Other versions
FI823824A7 (fi
FI823824A0 (fi
Inventor
Ernest Mohacsi
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI823824A0 publication Critical patent/FI823824A0/fi
Publication of FI823824L publication Critical patent/FI823824L/fi
Publication of FI823824A7 publication Critical patent/FI823824A7/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/28Morphinans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
FI823824A 1981-11-09 1982-11-08 Morfinaanijohdannaiset. FI823824A7 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/319,482 US4374139A (en) 1981-11-09 1981-11-09 Levorotatory N-substituted acylmorphinans useful as analgesic agents

Publications (3)

Publication Number Publication Date
FI823824A0 FI823824A0 (fi) 1982-11-08
FI823824L true FI823824L (fi) 1983-05-10
FI823824A7 FI823824A7 (fi) 1983-05-10

Family

ID=23242421

Family Applications (1)

Application Number Title Priority Date Filing Date
FI823824A FI823824A7 (fi) 1981-11-09 1982-11-08 Morfinaanijohdannaiset.

Country Status (18)

Country Link
US (1) US4374139A (cs)
EP (1) EP0079556A3 (cs)
JP (1) JPS5888364A (cs)
KR (1) KR840002357A (cs)
AU (1) AU9027682A (cs)
CA (1) CA1195324A (cs)
DK (1) DK491582A (cs)
ES (2) ES8500948A1 (cs)
FI (1) FI823824A7 (cs)
GR (1) GR78317B (cs)
HU (1) HU187425B (cs)
IL (1) IL67180A0 (cs)
MC (1) MC1490A1 (cs)
NO (1) NO823707L (cs)
NZ (1) NZ202404A (cs)
PH (1) PH18458A (cs)
PT (1) PT75815B (cs)
ZA (1) ZA827905B (cs)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4423221A (en) * 1982-06-10 1983-12-27 Sisa Pharmaceutical Laboratories, Inc. 7-Carboethoxy-morphinan-6-one compounds
US4454141A (en) * 1982-09-23 1984-06-12 Sisa Pharmaceutical Laboratories, Inc. Trans-B/C-7-(1-hydroxypentyl)-3-methoxy-17 methyl-6,7-didehydromorphinans, and methods of relieving pain with them
EP0184041A1 (en) * 1984-11-13 1986-06-11 Miles Inc. 6-Methylene morphinan purification technique
US4929622A (en) * 1987-09-24 1990-05-29 Hoechst-Roussel Pharmaceuticals, Inc. 2,6-Methanopyrrolo-3-benzazocines
DE4304450A1 (de) * 1993-02-13 1994-08-18 Boehringer Mannheim Gmbh System zur Zubereitung von Flüssigkeiten
ATE292625T1 (de) * 2000-10-31 2005-04-15 Rensselaer Polytech Inst 8-substituierte 2,6-methano-3-benzazocine und 3- substituierte morphinane als opioidrezeptorbindende agenzien
CA2450073C (en) 2001-07-25 2017-08-29 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
US20040204862A1 (en) * 2003-04-11 2004-10-14 Wainer Irving W. Computer-based model for identification and characterization for non-competitive inhibitors of nicotinic acetylcholine receptors and related ligand-gated ion channel receptors
JP2008539047A (ja) 2005-04-28 2008-11-13 プロテウス バイオメディカル インコーポレイテッド ファーマインフォーマティックスシステム
CN101594878A (zh) 2006-09-18 2009-12-02 雷普特药品公司 通过给予受体相关蛋白(rap)-缀合物对肝病症的治疗
EP3395372B1 (en) 2009-02-20 2022-04-06 EnhanX Biopharm Inc. Glutathione-based drug delivery system
SG10201402069PA (en) 2009-05-06 2014-07-30 Lab Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
SMT201900357T1 (it) 2009-12-04 2019-07-11 Alkermes Pharma Ireland Ltd Derivati di morfinano per trattamento di abuso di sostanze stupefacenti
WO2011119605A2 (en) 2010-03-22 2011-09-29 Rensselaer Polytechnic Institute Carboxamide biosiosteres of opiates
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
EP2725908B1 (en) 2011-06-29 2017-05-31 Alkermes, Inc. Peripherally acting opioid compounds
US9211293B2 (en) 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
CA2911231C (en) 2013-05-24 2021-12-07 Alkermes Pharma Ireland Limited Morphan and morphinan analogues, and methods of use
US9656961B2 (en) 2013-05-24 2017-05-23 Alkermes Pharma Ireland Limited Methods for treating depressive symptoms
WO2018125716A1 (en) * 2017-01-02 2018-07-05 Purdue Pharma L.P. Morphinan derivatives and use thereof
EP4243768A1 (en) 2020-11-12 2023-09-20 Alkermes Pharma Ireland Limited Immediate release multilayer tablet

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3723437A (en) * 1970-09-15 1973-03-27 American Home Prod 4,10-(methaniminomethano phenanthrene derivatives
ZA73988B (en) * 1972-03-10 1973-10-31 Hoffmann La Roche Morphinan derivatives
US3914233A (en) * 1972-10-20 1975-10-21 Hoffmann La Roche 4-Hydroxy-N-substituted morphinan derivatives

Also Published As

Publication number Publication date
ES517222A0 (es) 1984-12-01
ES529349A0 (es) 1985-08-01
PT75815A (en) 1982-12-01
HU187425B (en) 1986-01-28
ZA827905B (en) 1983-08-31
PH18458A (en) 1985-07-18
ES8500948A1 (es) 1984-12-01
GR78317B (cs) 1984-09-26
ES8506635A1 (es) 1985-08-01
EP0079556A3 (de) 1983-08-24
NZ202404A (en) 1985-11-08
MC1490A1 (fr) 1983-09-12
CA1195324A (en) 1985-10-15
DK491582A (da) 1983-05-10
FI823824A7 (fi) 1983-05-10
IL67180A0 (en) 1983-03-31
FI823824A0 (fi) 1982-11-08
JPS5888364A (ja) 1983-05-26
PT75815B (en) 1986-01-21
KR840002357A (ko) 1984-06-25
AU9027682A (en) 1983-05-19
US4374139A (en) 1983-02-15
EP0079556A2 (de) 1983-05-25
NO823707L (no) 1983-05-10

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: F HOFFMANN-LA ROCHE & CO