FI823824L - Morfinanderivat - Google Patents

Morfinanderivat

Info

Publication number
FI823824L
FI823824L FI823824A FI823824A FI823824L FI 823824 L FI823824 L FI 823824L FI 823824 A FI823824 A FI 823824A FI 823824 A FI823824 A FI 823824A FI 823824 L FI823824 L FI 823824L
Authority
FI
Finland
Prior art keywords
morfinanderivat
Prior art date
Application number
FI823824A
Other languages
English (en)
Finnish (fi)
Other versions
FI823824A0 (fi
FI823824A7 (fi
Inventor
Ernest Mohacsi
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI823824A0 publication Critical patent/FI823824A0/fi
Publication of FI823824A7 publication Critical patent/FI823824A7/fi
Publication of FI823824L publication Critical patent/FI823824L/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/28Morphinans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
FI823824A 1981-11-09 1982-11-08 Morfinanderivat FI823824L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/319,482 US4374139A (en) 1981-11-09 1981-11-09 Levorotatory N-substituted acylmorphinans useful as analgesic agents

Publications (3)

Publication Number Publication Date
FI823824A0 FI823824A0 (fi) 1982-11-08
FI823824A7 FI823824A7 (fi) 1983-05-10
FI823824L true FI823824L (fi) 1983-05-10

Family

ID=23242421

Family Applications (1)

Application Number Title Priority Date Filing Date
FI823824A FI823824L (fi) 1981-11-09 1982-11-08 Morfinanderivat

Country Status (18)

Country Link
US (1) US4374139A (cs)
EP (1) EP0079556A3 (cs)
JP (1) JPS5888364A (cs)
KR (1) KR840002357A (cs)
AU (1) AU9027682A (cs)
CA (1) CA1195324A (cs)
DK (1) DK491582A (cs)
ES (2) ES8500948A1 (cs)
FI (1) FI823824L (cs)
GR (1) GR78317B (cs)
HU (1) HU187425B (cs)
IL (1) IL67180A0 (cs)
MC (1) MC1490A1 (cs)
NO (1) NO823707L (cs)
NZ (1) NZ202404A (cs)
PH (1) PH18458A (cs)
PT (1) PT75815B (cs)
ZA (1) ZA827905B (cs)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4423221A (en) * 1982-06-10 1983-12-27 Sisa Pharmaceutical Laboratories, Inc. 7-Carboethoxy-morphinan-6-one compounds
US4454141A (en) * 1982-09-23 1984-06-12 Sisa Pharmaceutical Laboratories, Inc. Trans-B/C-7-(1-hydroxypentyl)-3-methoxy-17 methyl-6,7-didehydromorphinans, and methods of relieving pain with them
EP0184041A1 (en) * 1984-11-13 1986-06-11 Miles Inc. 6-Methylene morphinan purification technique
US4929622A (en) * 1987-09-24 1990-05-29 Hoechst-Roussel Pharmaceuticals, Inc. 2,6-Methanopyrrolo-3-benzazocines
DE4304450A1 (de) * 1993-02-13 1994-08-18 Boehringer Mannheim Gmbh System zur Zubereitung von Flüssigkeiten
ES2572332T3 (es) 2000-10-31 2016-05-31 Rensselaer Polytech Inst 2,6-metano-3-benzazocinas sustituidas en posición 8 y morfinanos sustituidos en posición 3 como ligandos de receptores opioides
EP1554572B1 (en) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
US20040204862A1 (en) * 2003-04-11 2004-10-14 Wainer Irving W. Computer-based model for identification and characterization for non-competitive inhibitors of nicotinic acetylcholine receptors and related ligand-gated ion channel receptors
CN102379684B (zh) 2005-04-28 2014-11-19 普罗透斯数字保健公司 药物信息系统
US8795627B2 (en) 2007-03-21 2014-08-05 Raptor Pharmaceuticals Inc. Treatment of liver disorders by administration of RAP conjugates
CN102316902B (zh) 2009-02-20 2014-09-24 to-BBB控股股份有限公司 基于谷胱甘肽的药物递送系统
IL295075A (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
EP3569234A1 (en) 2009-12-04 2019-11-20 Alkermes Pharma Ireland Limited Morphinan derivatives for the treatment of drug overdose
CA2793725C (en) 2010-03-22 2018-05-01 Rensselaer Polytechnic Institute Carboxamide bioisosteres of opiates
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
PT2725908T (pt) 2011-06-29 2017-08-31 Alkermes Inc Compostos opioides de ação periférica
US9211293B2 (en) 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
WO2014190271A2 (en) 2013-05-24 2014-11-27 Alkermes Pharma Ireland Limted Methods for treating depressive symptoms
CA2911231C (en) 2013-05-24 2021-12-07 Alkermes Pharma Ireland Limited Morphan and morphinan analogues, and methods of use
US10745402B2 (en) 2017-01-02 2020-08-18 Purdue Pharma L.P. Morphinan derivatives and use thereof
EP4243768A1 (en) 2020-11-12 2023-09-20 Alkermes Pharma Ireland Limited Immediate release multilayer tablet

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3723437A (en) * 1970-09-15 1973-03-27 American Home Prod 4,10-(methaniminomethano phenanthrene derivatives
ZA73988B (en) * 1972-03-10 1973-10-31 Hoffmann La Roche Morphinan derivatives
US3914233A (en) * 1972-10-20 1975-10-21 Hoffmann La Roche 4-Hydroxy-N-substituted morphinan derivatives

Also Published As

Publication number Publication date
IL67180A0 (en) 1983-03-31
FI823824A0 (fi) 1982-11-08
ES529349A0 (es) 1985-08-01
NZ202404A (en) 1985-11-08
PT75815B (en) 1986-01-21
ZA827905B (en) 1983-08-31
ES517222A0 (es) 1984-12-01
MC1490A1 (fr) 1983-09-12
NO823707L (no) 1983-05-10
DK491582A (da) 1983-05-10
CA1195324A (en) 1985-10-15
FI823824A7 (fi) 1983-05-10
AU9027682A (en) 1983-05-19
EP0079556A2 (de) 1983-05-25
KR840002357A (ko) 1984-06-25
US4374139A (en) 1983-02-15
ES8506635A1 (es) 1985-08-01
PT75815A (en) 1982-12-01
ES8500948A1 (es) 1984-12-01
HU187425B (en) 1986-01-28
GR78317B (cs) 1984-09-26
JPS5888364A (ja) 1983-05-26
EP0079556A3 (de) 1983-08-24
PH18458A (en) 1985-07-18

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: F HOFFMANN-LA ROCHE & CO