IL67180A0 - Morphinate derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Morphinate derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL67180A0
IL67180A0 IL67180A IL6718082A IL67180A0 IL 67180 A0 IL67180 A0 IL 67180A0 IL 67180 A IL67180 A IL 67180A IL 6718082 A IL6718082 A IL 6718082A IL 67180 A0 IL67180 A0 IL 67180A0
Authority
IL
Israel
Prior art keywords
morphinate
derivatives
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL67180A
Other languages
English (en)
Original Assignee
Sparamedica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sparamedica Ag filed Critical Sparamedica Ag
Publication of IL67180A0 publication Critical patent/IL67180A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/28—Morphinans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
IL67180A 1981-11-09 1982-11-05 Morphinate derivatives,their preparation and pharmaceutical compositions containing them IL67180A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/319,482 US4374139A (en) 1981-11-09 1981-11-09 Levorotatory N-substituted acylmorphinans useful as analgesic agents

Publications (1)

Publication Number Publication Date
IL67180A0 true IL67180A0 (en) 1983-03-31

Family

ID=23242421

Family Applications (1)

Application Number Title Priority Date Filing Date
IL67180A IL67180A0 (en) 1981-11-09 1982-11-05 Morphinate derivatives,their preparation and pharmaceutical compositions containing them

Country Status (18)

Country Link
US (1) US4374139A (xx)
EP (1) EP0079556A3 (xx)
JP (1) JPS5888364A (xx)
KR (1) KR840002357A (xx)
AU (1) AU9027682A (xx)
CA (1) CA1195324A (xx)
DK (1) DK491582A (xx)
ES (2) ES8500948A1 (xx)
FI (1) FI823824L (xx)
GR (1) GR78317B (xx)
HU (1) HU187425B (xx)
IL (1) IL67180A0 (xx)
MC (1) MC1490A1 (xx)
NO (1) NO823707L (xx)
NZ (1) NZ202404A (xx)
PH (1) PH18458A (xx)
PT (1) PT75815B (xx)
ZA (1) ZA827905B (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4423221A (en) * 1982-06-10 1983-12-27 Sisa Pharmaceutical Laboratories, Inc. 7-Carboethoxy-morphinan-6-one compounds
US4454141A (en) * 1982-09-23 1984-06-12 Sisa Pharmaceutical Laboratories, Inc. Trans-B/C-7-(1-hydroxypentyl)-3-methoxy-17 methyl-6,7-didehydromorphinans, and methods of relieving pain with them
EP0184041A1 (en) * 1984-11-13 1986-06-11 Miles Inc. 6-Methylene morphinan purification technique
US4929622A (en) * 1987-09-24 1990-05-29 Hoechst-Roussel Pharmaceuticals, Inc. 2,6-Methanopyrrolo-3-benzazocines
DE4304450A1 (de) * 1993-02-13 1994-08-18 Boehringer Mannheim Gmbh System zur Zubereitung von Flüssigkeiten
CA2426942C (en) * 2000-10-31 2014-06-03 Mark P. Wentland 8-carboxamido-2,6-methano-3-benzazocines
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
US20040204862A1 (en) * 2003-04-11 2004-10-14 Wainer Irving W. Computer-based model for identification and characterization for non-competitive inhibitors of nicotinic acetylcholine receptors and related ligand-gated ion channel receptors
SI1889198T1 (sl) 2005-04-28 2015-02-27 Proteus Digital Health, Inc. Farma-informacijski sistem
MX2009002893A (es) 2006-09-18 2009-07-10 Raptor Pharmaceutical Inc Tratamiento de trastornos hepaticos mediante la administracion de conjugados de la proteina asociada al receptor (rap).
WO2010095940A2 (en) 2009-02-20 2010-08-26 To-Bbb Holding B.V. Glutathione-based drug delivery system
NZ596876A (en) 2009-05-06 2014-01-31 Lab Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
EP2506712B8 (en) 2009-12-04 2019-06-19 Alkermes Pharma Ireland Limited Morphinan derivatives for the treatment of drug overdose
CA2793725C (en) 2010-03-22 2018-05-01 Rensselaer Polytechnic Institute Carboxamide bioisosteres of opiates
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
PL2725908T3 (pl) 2011-06-29 2017-10-31 Alkermes Inc Działające obwodowo związki opioidowe
US9211293B2 (en) 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
EP3003311A2 (en) 2013-05-24 2016-04-13 Alkermes Pharma Ireland Limited Methods for treating depressive symptoms
AU2014268361B2 (en) 2013-05-24 2018-09-06 Alkermes Pharma Ireland Limited Morphan and morphinan analogues, and methods of use
WO2018125716A1 (en) * 2017-01-02 2018-07-05 Purdue Pharma L.P. Morphinan derivatives and use thereof
EP4243768A1 (en) 2020-11-12 2023-09-20 Alkermes Pharma Ireland Limited Immediate release multilayer tablet

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3723437A (en) * 1970-09-15 1973-03-27 American Home Prod 4,10-(methaniminomethano phenanthrene derivatives
ZA73988B (en) * 1972-03-10 1973-10-31 Hoffmann La Roche Morphinan derivatives
US3914233A (en) * 1972-10-20 1975-10-21 Hoffmann La Roche 4-Hydroxy-N-substituted morphinan derivatives

Also Published As

Publication number Publication date
FI823824A0 (fi) 1982-11-08
FI823824L (fi) 1983-05-10
GR78317B (xx) 1984-09-26
EP0079556A2 (de) 1983-05-25
ZA827905B (en) 1983-08-31
CA1195324A (en) 1985-10-15
US4374139A (en) 1983-02-15
JPS5888364A (ja) 1983-05-26
NZ202404A (en) 1985-11-08
PT75815B (en) 1986-01-21
DK491582A (da) 1983-05-10
PH18458A (en) 1985-07-18
HU187425B (en) 1986-01-28
ES517222A0 (es) 1984-12-01
EP0079556A3 (de) 1983-08-24
ES8506635A1 (es) 1985-08-01
ES529349A0 (es) 1985-08-01
KR840002357A (ko) 1984-06-25
AU9027682A (en) 1983-05-19
NO823707L (no) 1983-05-10
PT75815A (en) 1982-12-01
ES8500948A1 (es) 1984-12-01
MC1490A1 (fr) 1983-09-12

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