ZA827905B - Morphinane derivatives - Google Patents
Morphinane derivativesInfo
- Publication number
- ZA827905B ZA827905B ZA827905A ZA827905A ZA827905B ZA 827905 B ZA827905 B ZA 827905B ZA 827905 A ZA827905 A ZA 827905A ZA 827905 A ZA827905 A ZA 827905A ZA 827905 B ZA827905 B ZA 827905B
- Authority
- ZA
- South Africa
- Prior art keywords
- morphinane derivatives
- morphinane
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/28—Morphinans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/319,482 US4374139A (en) | 1981-11-09 | 1981-11-09 | Levorotatory N-substituted acylmorphinans useful as analgesic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA827905B true ZA827905B (en) | 1983-08-31 |
Family
ID=23242421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA827905A ZA827905B (en) | 1981-11-09 | 1982-10-28 | Morphinane derivatives |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4374139A (cs) |
| EP (1) | EP0079556A3 (cs) |
| JP (1) | JPS5888364A (cs) |
| KR (1) | KR840002357A (cs) |
| AU (1) | AU9027682A (cs) |
| CA (1) | CA1195324A (cs) |
| DK (1) | DK491582A (cs) |
| ES (2) | ES8500948A1 (cs) |
| FI (1) | FI823824A7 (cs) |
| GR (1) | GR78317B (cs) |
| HU (1) | HU187425B (cs) |
| IL (1) | IL67180A0 (cs) |
| MC (1) | MC1490A1 (cs) |
| NO (1) | NO823707L (cs) |
| NZ (1) | NZ202404A (cs) |
| PH (1) | PH18458A (cs) |
| PT (1) | PT75815B (cs) |
| ZA (1) | ZA827905B (cs) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4423221A (en) * | 1982-06-10 | 1983-12-27 | Sisa Pharmaceutical Laboratories, Inc. | 7-Carboethoxy-morphinan-6-one compounds |
| US4454141A (en) * | 1982-09-23 | 1984-06-12 | Sisa Pharmaceutical Laboratories, Inc. | Trans-B/C-7-(1-hydroxypentyl)-3-methoxy-17 methyl-6,7-didehydromorphinans, and methods of relieving pain with them |
| EP0184041A1 (en) * | 1984-11-13 | 1986-06-11 | Miles Inc. | 6-Methylene morphinan purification technique |
| US4929622A (en) * | 1987-09-24 | 1990-05-29 | Hoechst-Roussel Pharmaceuticals, Inc. | 2,6-Methanopyrrolo-3-benzazocines |
| DE4304450A1 (de) * | 1993-02-13 | 1994-08-18 | Boehringer Mannheim Gmbh | System zur Zubereitung von Flüssigkeiten |
| ATE292625T1 (de) * | 2000-10-31 | 2005-04-15 | Rensselaer Polytech Inst | 8-substituierte 2,6-methano-3-benzazocine und 3- substituierte morphinane als opioidrezeptorbindende agenzien |
| CA2450073C (en) | 2001-07-25 | 2017-08-29 | Biomarin Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| US20040204862A1 (en) * | 2003-04-11 | 2004-10-14 | Wainer Irving W. | Computer-based model for identification and characterization for non-competitive inhibitors of nicotinic acetylcholine receptors and related ligand-gated ion channel receptors |
| JP2008539047A (ja) | 2005-04-28 | 2008-11-13 | プロテウス バイオメディカル インコーポレイテッド | ファーマインフォーマティックスシステム |
| CN101594878A (zh) | 2006-09-18 | 2009-12-02 | 雷普特药品公司 | 通过给予受体相关蛋白（rap）-缀合物对肝病症的治疗 |
| EP3395372B1 (en) | 2009-02-20 | 2022-04-06 | EnhanX Biopharm Inc. | Glutathione-based drug delivery system |
| SG10201402069PA (en) | 2009-05-06 | 2014-07-30 | Lab Skin Care Inc | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same |
| SMT201900357T1 (it) | 2009-12-04 | 2019-07-11 | Alkermes Pharma Ireland Ltd | Derivati di morfinano per trattamento di abuso di sostanze stupefacenti |
| WO2011119605A2 (en) | 2010-03-22 | 2011-09-29 | Rensselaer Polytechnic Institute | Carboxamide biosiosteres of opiates |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
| EP2725908B1 (en) | 2011-06-29 | 2017-05-31 | Alkermes, Inc. | Peripherally acting opioid compounds |
| US9211293B2 (en) | 2011-12-15 | 2015-12-15 | Alkermes Pharma Ireland Limited | Opioid agonist antagonist combinations |
| CA2911231C (en) | 2013-05-24 | 2021-12-07 | Alkermes Pharma Ireland Limited | Morphan and morphinan analogues, and methods of use |
| US9656961B2 (en) | 2013-05-24 | 2017-05-23 | Alkermes Pharma Ireland Limited | Methods for treating depressive symptoms |
| WO2018125716A1 (en) * | 2017-01-02 | 2018-07-05 | Purdue Pharma L.P. | Morphinan derivatives and use thereof |
| EP4243768A1 (en) | 2020-11-12 | 2023-09-20 | Alkermes Pharma Ireland Limited | Immediate release multilayer tablet |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3723437A (en) * | 1970-09-15 | 1973-03-27 | American Home Prod | 4,10-(methaniminomethano phenanthrene derivatives |
| ZA73988B (en) * | 1972-03-10 | 1973-10-31 | Hoffmann La Roche | Morphinan derivatives |
| US3914233A (en) * | 1972-10-20 | 1975-10-21 | Hoffmann La Roche | 4-Hydroxy-N-substituted morphinan derivatives |
-
1981
- 1981-11-09 US US06/319,482 patent/US4374139A/en not_active Expired - Fee Related
- 1981-12-29 GR GR69729A patent/GR78317B/el unknown
-
1982
- 1982-10-28 ZA ZA827905A patent/ZA827905B/xx unknown
- 1982-11-05 DK DK491582A patent/DK491582A/da not_active Application Discontinuation
- 1982-11-05 IL IL67180A patent/IL67180A0/xx unknown
- 1982-11-05 NZ NZ202404A patent/NZ202404A/en unknown
- 1982-11-08 NO NO823707A patent/NO823707L/no unknown
- 1982-11-08 PH PH28105A patent/PH18458A/en unknown
- 1982-11-08 ES ES517222A patent/ES8500948A1/es not_active Expired
- 1982-11-08 EP EP82110285A patent/EP0079556A3/de not_active Ceased
- 1982-11-08 MC MC821609A patent/MC1490A1/xx unknown
- 1982-11-08 CA CA000415102A patent/CA1195324A/en not_active Expired
- 1982-11-08 PT PT75815A patent/PT75815B/pt unknown
- 1982-11-08 FI FI823824A patent/FI823824A7/fi not_active Application Discontinuation
- 1982-11-08 HU HU823578A patent/HU187425B/hu unknown
- 1982-11-08 JP JP57194799A patent/JPS5888364A/ja active Pending
- 1982-11-09 KR KR1019820005066A patent/KR840002357A/ko not_active Withdrawn
- 1982-11-09 AU AU90276/82A patent/AU9027682A/en not_active Abandoned
-
1984
- 1984-02-01 ES ES529349A patent/ES8506635A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES517222A0 (es) | 1984-12-01 |
| ES529349A0 (es) | 1985-08-01 |
| PT75815A (en) | 1982-12-01 |
| HU187425B (en) | 1986-01-28 |
| PH18458A (en) | 1985-07-18 |
| FI823824L (fi) | 1983-05-10 |
| ES8500948A1 (es) | 1984-12-01 |
| GR78317B (cs) | 1984-09-26 |
| ES8506635A1 (es) | 1985-08-01 |
| EP0079556A3 (de) | 1983-08-24 |
| NZ202404A (en) | 1985-11-08 |
| MC1490A1 (fr) | 1983-09-12 |
| CA1195324A (en) | 1985-10-15 |
| DK491582A (da) | 1983-05-10 |
| FI823824A7 (fi) | 1983-05-10 |
| IL67180A0 (en) | 1983-03-31 |
| FI823824A0 (fi) | 1982-11-08 |
| JPS5888364A (ja) | 1983-05-26 |
| PT75815B (en) | 1986-01-21 |
| KR840002357A (ko) | 1984-06-25 |
| AU9027682A (en) | 1983-05-19 |
| US4374139A (en) | 1983-02-15 |
| EP0079556A2 (de) | 1983-05-25 |
| NO823707L (no) | 1983-05-10 |
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