IL66679A - Process for the preparation or 6-alkyl-8-amino-(or 3,3-di-alkylureido)ergoline derivatives - Google Patents

Process for the preparation or 6-alkyl-8-amino-(or 3,3-di-alkylureido)ergoline derivatives

Info

Publication number
IL66679A
IL66679A IL66679A IL6667982A IL66679A IL 66679 A IL66679 A IL 66679A IL 66679 A IL66679 A IL 66679A IL 6667982 A IL6667982 A IL 6667982A IL 66679 A IL66679 A IL 66679A
Authority
IL
Israel
Prior art keywords
alkylureido
alkyl
amino
preparation
hydrogen
Prior art date
Application number
IL66679A
Other languages
English (en)
Other versions
IL66679A0 (en
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL66679A0 publication Critical patent/IL66679A0/xx
Publication of IL66679A publication Critical patent/IL66679A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL66679A 1981-09-03 1982-08-30 Process for the preparation or 6-alkyl-8-amino-(or 3,3-di-alkylureido)ergoline derivatives IL66679A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3135305A DE3135305C2 (de) 1981-09-03 1981-09-03 Verfahren zur Herstellung von 8-Ergolinyl-harnstoffen

Publications (2)

Publication Number Publication Date
IL66679A0 IL66679A0 (en) 1982-12-31
IL66679A true IL66679A (en) 1986-04-29

Family

ID=6141023

Family Applications (1)

Application Number Title Priority Date Filing Date
IL66679A IL66679A (en) 1981-09-03 1982-08-30 Process for the preparation or 6-alkyl-8-amino-(or 3,3-di-alkylureido)ergoline derivatives

Country Status (17)

Country Link
US (1) US4748248A (enExample)
EP (1) EP0074921B1 (enExample)
JP (1) JPS5855483A (enExample)
AT (1) ATE11289T1 (enExample)
AU (1) AU555576B2 (enExample)
CA (1) CA1175813A (enExample)
CS (1) CS241122B2 (enExample)
DD (1) DD203544A5 (enExample)
DE (2) DE3135305C2 (enExample)
DK (1) DK161646C (enExample)
ES (1) ES8305361A1 (enExample)
GR (1) GR76897B (enExample)
HU (1) HU186969B (enExample)
IE (1) IE53437B1 (enExample)
IL (1) IL66679A (enExample)
SU (1) SU1272988A3 (enExample)
YU (1) YU199282A (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3151912A1 (de) * 1981-12-23 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
DE3309493A1 (de) * 1983-03-14 1984-09-20 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ergolin-derivate, verfahren zu ihrer herstellung sowie verwendung als arzneimittel
CH666035A5 (de) * 1984-12-24 1988-06-30 Sandoz Ag 8-alpha-acylaminoergolene.
DE3915950A1 (de) * 1989-05-12 1990-11-15 Schering Ag 8(alpha)-acylamino-ergoline, ihre herstellung und verwendung als arzneimittel
US20060171795A1 (en) * 2005-01-28 2006-08-03 Cromwell Stephen D Substantial embedment of metallic debris
JP2010119349A (ja) * 2008-11-20 2010-06-03 Shinichi Okamoto 即席のパンなどの穀物粉加工食品の製造方法
CA2974113A1 (en) 2015-01-20 2016-07-28 Xoc Pharmaceuticals, Inc. Isoergoline compounds and uses thereof
BR112017015487A2 (pt) 2015-01-20 2018-01-30 Xoc Pharmaceuticals Inc Composto; composição; método de tratamento e/ou prevenção de enxaqueca, als, doença de alzheimer, doença de parkinson, distúrbios extrapirimidais, depressão, náusea, êmese, síndrome das pernas inquietas, insônia, agressão, doença de huntington, doença cardiopulmonar, fibrogênese, hipertensão arterial pulmonar, ansiedade, dependências a drogas, distonia, parassonia ou hiperlactinemia em um indivíduo; métodos de agonização dos receptores d2, 5-ht1d, 5-ht1a e 5-ht2c, em um indivíduo; método de antagonização do receptor d3 em um indivíduo; métodos de agonização seletiva dos receptores 5 -ht1d, e 5-ht2c, método de fornecimento de atividade de antagonista funcional no receptor 5 -ht2b ou no receptor 5-ht7, ou em ambos, em um indivíduo; método de fornecimento de atividade de antagonista funcional nos receptores adrenérgicos em um indivíduo
CA3064274A1 (en) 2017-06-01 2018-12-06 Xoc Pharmaceuticals, Inc. Ergoline derivatives for use in medicine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0021206B1 (de) * 1979-06-13 1983-06-22 Schering Aktiengesellschaft Neue (Ergolin-yl)-N', N'-diäthylharnstoff-Derivate, ihre Herstellung und sie enthaltende Arzneimittel

Also Published As

Publication number Publication date
DE3135305C2 (de) 1983-07-21
ES515428A0 (es) 1983-05-01
JPH0239511B2 (enExample) 1990-09-05
DK161646B (da) 1991-07-29
DK368382A (da) 1983-03-04
YU199282A (en) 1985-03-20
IE53437B1 (en) 1988-11-09
AU8786382A (en) 1983-03-10
EP0074921A1 (en) 1983-03-23
EP0074921B1 (en) 1985-01-16
DK161646C (da) 1992-01-06
AU555576B2 (en) 1986-10-02
HU186969B (en) 1985-10-28
ATE11289T1 (de) 1985-02-15
IE822156L (en) 1983-03-03
IL66679A0 (en) 1982-12-31
CA1175813A (en) 1984-10-09
US4748248A (en) 1988-05-31
JPS5855483A (ja) 1983-04-01
GR76897B (enExample) 1984-09-04
DE3135305A1 (de) 1983-03-10
DE3261963D1 (en) 1985-02-28
CS642282A2 (en) 1985-07-16
SU1272988A3 (ru) 1986-11-23
ES8305361A1 (es) 1983-05-01
CS241122B2 (en) 1986-03-13
DD203544A5 (de) 1983-10-26

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