IL66614A - Method of constructing a dna sequence encoding a polypeptide,microbial production of human serum albumin,and pharmaceutical compositions comprising it - Google Patents

Method of constructing a dna sequence encoding a polypeptide,microbial production of human serum albumin,and pharmaceutical compositions comprising it

Info

Publication number
IL66614A
IL66614A IL66614A IL6661482A IL66614A IL 66614 A IL66614 A IL 66614A IL 66614 A IL66614 A IL 66614A IL 6661482 A IL6661482 A IL 6661482A IL 66614 A IL66614 A IL 66614A
Authority
IL
Israel
Prior art keywords
polypeptide
fragments
serum albumin
human serum
constructing
Prior art date
Application number
IL66614A
Other languages
English (en)
Other versions
IL66614A0 (en
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23146077&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL66614(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of IL66614A0 publication Critical patent/IL66614A0/xx
Publication of IL66614A publication Critical patent/IL66614A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL66614A 1981-08-28 1982-08-23 Method of constructing a dna sequence encoding a polypeptide,microbial production of human serum albumin,and pharmaceutical compositions comprising it IL66614A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29738081A 1981-08-28 1981-08-28

Publications (2)

Publication Number Publication Date
IL66614A0 IL66614A0 (en) 1982-12-31
IL66614A true IL66614A (en) 1985-09-29

Family

ID=23146077

Family Applications (1)

Application Number Title Priority Date Filing Date
IL66614A IL66614A (en) 1981-08-28 1982-08-23 Method of constructing a dna sequence encoding a polypeptide,microbial production of human serum albumin,and pharmaceutical compositions comprising it

Country Status (14)

Country Link
EP (1) EP0073646B1 (da)
JP (4) JPS5856684A (da)
KR (1) KR840001216A (da)
AT (1) ATE43138T1 (da)
AU (2) AU8775582A (da)
CA (1) CA1221927A (da)
DE (1) DE3279699D1 (da)
DK (1) DK169726B1 (da)
ES (1) ES8401133A1 (da)
GB (2) GB2105343B (da)
IE (1) IE53892B1 (da)
IL (1) IL66614A (da)
NZ (1) NZ201704A (da)
ZA (1) ZA826250B (da)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0079739A3 (en) * 1981-11-12 1984-08-08 The Upjohn Company Albumin-based nucleotides, their replication and use, and plasmids for use therein
EP0091527A3 (en) * 1981-12-14 1984-07-25 The President And Fellows Of Harvard College Dna sequences, recombinant dna molecules and processes for producing human serum albumin-like polypeptides
FR2579223B1 (fr) * 1985-03-25 1988-12-09 Genetica Procede de preparation microbiologique de la serum-albumine humaine
AU5890286A (en) * 1985-06-17 1986-12-24 Genex Corp. Cloned human serum albumin gene
US4956282A (en) * 1985-07-29 1990-09-11 Calgene, Inc. Mammalian peptide expression in plant cells
FR2594846B1 (fr) * 1986-02-21 1989-10-20 Genetica Procede de preparation de la serum albumine humaine mature
IE62458B1 (en) * 1987-07-28 1995-02-08 Gist Brocades Nv Kluyveromyces as a host strain
US5879907A (en) * 1987-09-14 1999-03-09 Skandigen Ab Artificial gene coding for authentic human serum albumin, use thereof and method
SE459586B (sv) * 1987-09-14 1989-07-17 Mta Szegedi Biolog Koezponti Strukturgen som kodar foer autentiskt humant serum albumin och foerfarande foer dess framstaellning
GB8725529D0 (en) * 1987-10-30 1987-12-02 Delta Biotechnology Ltd Polypeptides
IL88326A (en) * 1987-11-18 1993-03-15 Gist Brocades Nv Purification of serum albumin
JPH01215289A (ja) * 1988-02-22 1989-08-29 Toa Nenryo Kogyo Kk 遺伝子組換えによる正常ヒト血清アルブミンａの製造方法
US4990447A (en) * 1988-06-24 1991-02-05 Gist-Brocades Nv Process for the purification of serum albumin
US5260202A (en) * 1988-09-07 1993-11-09 Delta Biotechnology Limited Fermentation method
GB8820951D0 (en) * 1988-09-07 1988-10-05 Delta Biotechnology Ltd Fermentation method
US5759802A (en) * 1988-10-26 1998-06-02 Tonen Corporation Production of human serum alubumin A
JPH0671432B2 (ja) * 1991-03-20 1994-09-14 株式会社ミドリ十字 ヒト血清アルブミンの製造方法
CA2058820C (en) * 1991-04-25 2003-07-15 Kotikanyad Sreekrishna Expression cassettes and vectors for the secretion of human serum albumin in pichia pastoris cells
US5330901A (en) * 1991-04-26 1994-07-19 Research Corporation Technologies, Inc. Expression of human serum albumin in Pichia pastoris
US5849874A (en) * 1991-07-12 1998-12-15 Gist-Brocades, N.V. Process for the purification of serum albumin
ES2141715T3 (es) 1991-07-12 2000-04-01 Dsm Nv Procedimiento para la purificacion de albumina de suero.
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
JPH07102148B2 (ja) * 1992-05-20 1995-11-08 株式会社ミドリ十字 遺伝子操作により得られるヒト血清アルブミンの製造方法、およびそれにより得られるヒト血清アルブミン含有組成物
US5728553A (en) 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
JPH07308199A (ja) 1994-05-18 1995-11-28 Green Cross Corp:The ヒト血清アルブミンの製造方法
GB9526733D0 (en) 1995-12-30 1996-02-28 Delta Biotechnology Ltd Fusion proteins
GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
WO2001077137A1 (en) 2000-04-12 2001-10-18 Human Genome Sciences, Inc. Albumin fusion proteins
US6946134B1 (en) 2000-04-12 2005-09-20 Human Genome Sciences, Inc. Albumin fusion proteins
JP4798832B2 (ja) 2000-10-24 2011-10-19 一般財団法人化学及血清療法研究所 ヒト血清アルブミン多量体の除去方法
JP4798833B2 (ja) 2000-10-24 2011-10-19 一般財団法人化学及血清療法研究所 加熱処理工程を含むヒト血清アルブミンの製造方法
US7507413B2 (en) 2001-04-12 2009-03-24 Human Genome Sciences, Inc. Albumin fusion proteins
JP5424521B2 (ja) 2001-12-21 2014-02-26 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド アルブミン融合タンパク質
GB0329722D0 (en) 2003-12-23 2004-01-28 Delta Biotechnology Ltd Modified plasmid and use thereof
GB0329681D0 (en) 2003-12-23 2004-01-28 Delta Biotechnology Ltd Gene expression technique
CN1934128B (zh) 2004-01-20 2011-01-26 财团法人化学及血清疗法研究所 在2价阳离子存在下通过加热处理制备人血清白蛋白的方法
JP4651282B2 (ja) * 2004-01-21 2011-03-16 田辺三菱製薬株式会社 造血幹細胞及び造血前駆細胞の増幅方法
JP4492156B2 (ja) 2004-03-03 2010-06-30 ニプロ株式会社 血清アルブミンドメインを含む蛋白質
DK2330200T3 (da) 2004-12-23 2017-07-24 Albumedix As Gene expression technique
KR20110020819A (ko) 2008-05-15 2011-03-03 가부시키가이샤 아루떼꾸 우에노 안구건조증 및/또는 각막/결막 질환 치료용 약학 조성물
CN106986933A (zh) 2009-02-11 2017-07-28 阿尔布梅迪克斯医疗公司 白蛋白变体和缀合物
CN102405279B (zh) 2009-04-09 2015-10-21 塞尔卡有限公司 改善单细胞克隆的方法
SG10201606161UA (en) 2011-07-05 2016-09-29 Novozymes Biopharma Dk As Albumin Formulation and Use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4719177A (en) * 1981-04-20 1988-01-12 Massachusetts Institute Of Technology Production of complementary DNA representing RNA viral sequences by recombinant DNA methods and uses therefor
FR2506326A1 (fr) * 1981-05-19 1982-11-26 Pasteur Institut Fragments d'adn portant des parties de l'information genetique des poliovirus, notamment du type pv1, et procede pour leur obtention
EP0079739A3 (en) * 1981-11-12 1984-08-08 The Upjohn Company Albumin-based nucleotides, their replication and use, and plasmids for use therein
EP0091527A3 (en) * 1981-12-14 1984-07-25 The President And Fellows Of Harvard College Dna sequences, recombinant dna molecules and processes for producing human serum albumin-like polypeptides

Also Published As

Publication number Publication date
IL66614A0 (en) 1982-12-31
JP2968052B2 (ja) 1999-10-25
CA1221927A (en) 1987-05-19
DE3279699D1 (en) 1989-06-22
ZA826250B (en) 1983-09-28
EP0073646B1 (en) 1989-05-17
IE822085L (en) 1983-02-28
DK169726B1 (da) 1995-01-23
AU603394B2 (en) 1990-11-15
JPH0460639B2 (da) 1992-09-28
GB8423932D0 (en) 1984-10-31
JPH08228790A (ja) 1996-09-10
AU8775582A (en) 1983-03-03
IE53892B1 (en) 1989-04-12
AU8146187A (en) 1988-03-17
EP0073646A2 (en) 1983-03-09
GB2147903A (en) 1985-05-22
JPS5856684A (ja) 1983-04-04
JPH0662841A (ja) 1994-03-08
NZ201704A (en) 1986-08-08
EP0073646A3 (en) 1984-08-01
GB2105343A (en) 1983-03-23
ES515259A0 (es) 1983-12-01
ES8401133A1 (es) 1983-12-01
JPH0775538B2 (ja) 1995-08-16
GB2105343B (en) 1985-12-24
ATE43138T1 (de) 1989-06-15
GB2147903B (en) 1985-12-24
DK384582A (da) 1983-03-01
KR840001216A (ko) 1984-03-28
JPH05292993A (ja) 1993-11-09

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Legal Events

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