IL65858A - 4-demethoxy-6(11)-deoxy-doxorubicin and daunorubicin derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

4-demethoxy-6(11)-deoxy-doxorubicin and daunorubicin derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL65858A
IL65858A IL65858A IL6585882A IL65858A IL 65858 A IL65858 A IL 65858A IL 65858 A IL65858 A IL 65858A IL 6585882 A IL6585882 A IL 6585882A IL 65858 A IL65858 A IL 65858A
Authority
IL
Israel
Prior art keywords
demethoxy
deoxy
doxorubicin
preparation
pharmaceutical compositions
Prior art date
Application number
IL65858A
Other languages
English (en)
Other versions
IL65858A0 (en
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of IL65858A0 publication Critical patent/IL65858A0/xx
Publication of IL65858A publication Critical patent/IL65858A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/38—Quinones containing —CHO or non—quinoid keto groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL65858A 1981-05-28 1982-05-24 4-demethoxy-6(11)-deoxy-doxorubicin and daunorubicin derivatives,their preparation and pharmaceutical compositions containing them IL65858A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8116264 1981-05-28
GB8125949 1981-08-22

Publications (2)

Publication Number Publication Date
IL65858A0 IL65858A0 (en) 1982-08-31
IL65858A true IL65858A (en) 1985-07-31

Family

ID=26279611

Family Applications (1)

Application Number Title Priority Date Filing Date
IL65858A IL65858A (en) 1981-05-28 1982-05-24 4-demethoxy-6(11)-deoxy-doxorubicin and daunorubicin derivatives,their preparation and pharmaceutical compositions containing them

Country Status (16)

Country Link
US (2) US4465671A (xx)
AU (2) AU564016B2 (xx)
CA (1) CA1210390A (xx)
CH (1) CH652131A5 (xx)
DE (2) DE3219380C2 (xx)
DK (1) DK239382A (xx)
FI (1) FI75833C (xx)
FR (2) FR2506772B1 (xx)
GB (1) GB2100257B (xx)
HU (2) HU190015B (xx)
IE (1) IE53120B1 (xx)
IL (1) IL65858A (xx)
IT (1) IT1210476B (xx)
NL (1) NL8202102A (xx)
SE (2) SE458685B (xx)
YU (2) YU113082A (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5138042A (en) * 1981-05-28 1992-08-11 Farmitalia Carlo Erba S.P.A. 6-deoxyanthracyclines
IT1210476B (it) * 1981-05-28 1989-09-14 Erba Farmitalia Antracicline.
GB8317037D0 (en) * 1983-06-23 1983-07-27 Erba Farmitalia 6-deoxyanthracyclines
DE3233020A1 (de) * 1981-09-18 1983-04-07 Farmitalia Carlo Erba S.p.A., 20159 Milano Verfahren zur herstellung von 4-demethoxy-7,9-dideoxydaunomycinon
IT1155446B (it) * 1982-12-23 1987-01-28 Erba Farmitalia Procedimento per la purificazione di glucosidi antraciclinonici mediante adsobimento selettivo su resine
DE3422735C2 (de) * 1983-06-23 1996-07-11 Erba Carlo Spa Anthracyclinglykoside, Verfahren zu deren Herstellung und Arzneimittel, welche diese enthalten
FR2560600B1 (fr) * 1983-06-23 1988-01-15 Erba Farmitalia Glycosides d'anthracyclines, procede pour les preparer, medicament les contenant
FR2551057B1 (fr) * 1983-08-30 1986-07-18 Hoechst Lab Nouveaux aglycones utiles pour la preparation des antibiotiques et des antitumoraux de la serie des anthracyclines et leurs procedes de preparation
GB8421491D0 (en) * 1984-08-24 1984-09-26 Erba Farmitalia Anthracycline glycosides
GB8426672D0 (en) * 1984-10-22 1984-11-28 Erba Farmitalia Pharmaceutical compositions
US4634765A (en) * 1984-12-18 1987-01-06 Merrell Dow Pharmaceuticals Inc. Homodisaccharide hypoglycemic agents
GB2182926B (en) * 1985-11-19 1989-10-04 Erba Farmitalia Nitro anthracyclines, process for their preparation and use thereof
GB8905668D0 (en) * 1989-03-13 1989-04-26 Erba Carlo Spa New 3'-(4-morpholinyl)-and 3'-(2-methoxy-4-morpholinyl)-anthracycline derivatives
US5948896A (en) * 1997-08-13 1999-09-07 Gem Pharmaceuticals Processes for preparing 13-deoxy anthracycline derivatives
US5942605A (en) * 1998-03-03 1999-08-24 Gem Pharmaceuticals, Inc. 5-imino-13-deoxy anthracycline derivatives, their uses, and processes for preparing them

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE44954C (de) * FARBENFABRIKEN VORM. FRIEDR. BAYER & CO. in Elberfeld Verfahren zur Darstellung gelbbis rothbrauner, im alkalischen Bade färbender Azofarbstoffe aus Chrysoidin
GB1467383A (en) * 1974-06-12 1977-03-16 Farmaceutici Italia Daunomycin analogues
NL7900869A (nl) * 1978-02-09 1979-08-13 Erba Farmitalia Anthracyclinenantibiotica.
IT1098212B (it) * 1978-05-09 1985-09-07 Farmaceutici Italia Antracioline antitumorali sostituite
JPS5756494A (en) * 1980-09-22 1982-04-05 Microbial Chem Res Found New anthracyclin derivative
IT1210476B (it) * 1981-05-28 1989-09-14 Erba Farmitalia Antracicline.

Also Published As

Publication number Publication date
FI75833C (fi) 1988-08-08
GB2100257A (en) 1982-12-22
DK239382A (da) 1982-11-29
SE8704116L (sv) 1987-10-22
DE3219380A1 (de) 1982-12-16
DE3249834C2 (xx) 1989-08-03
AU576684B2 (en) 1988-09-01
CA1210390A (en) 1986-08-26
FR2514754A1 (xx) 1983-04-22
IT1210476B (it) 1989-09-14
HU190015B (en) 1986-08-28
SE458685B (sv) 1989-04-24
SE8704116D0 (sv) 1987-10-22
YU191984A (en) 1985-04-30
AU6173186A (en) 1987-01-08
IE821260L (en) 1982-11-28
FI75833B (fi) 1988-04-29
AU564016B2 (en) 1987-07-30
CH652131A5 (de) 1985-10-31
FR2514754B1 (xx) 1985-12-13
HU199767B (en) 1990-03-28
NL8202102A (nl) 1982-12-16
IL65858A0 (en) 1982-08-31
YU113082A (en) 1985-04-30
DE3219380C2 (de) 1986-12-04
IE53120B1 (en) 1988-07-06
FR2506772A1 (fr) 1982-12-03
US4600537A (en) 1986-07-15
FR2506772B1 (fr) 1985-10-18
IT8220606A0 (it) 1982-04-06
AU8412782A (en) 1982-12-02
SE8203274L (sv) 1982-11-29
US4465671A (en) 1984-08-14
GB2100257B (en) 1985-09-25
FI821833A0 (fi) 1982-05-24

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