IL63960A - Pharmaceutical compositions comprising prostaglandins and ascorbyl palmitate as stabilizer - Google Patents
Pharmaceutical compositions comprising prostaglandins and ascorbyl palmitate as stabilizerInfo
- Publication number
- IL63960A IL63960A IL63960A IL6396081A IL63960A IL 63960 A IL63960 A IL 63960A IL 63960 A IL63960 A IL 63960A IL 6396081 A IL6396081 A IL 6396081A IL 63960 A IL63960 A IL 63960A
- Authority
- IL
- Israel
- Prior art keywords
- ascorbyl palmitate
- pharmaceutical compositions
- prostaglandins
- stabilizer
- prostaglandin
- Prior art date
Links
- 239000011786 L-ascorbyl-6-palmitate Substances 0.000 title abstract 3
- 150000003180 prostaglandins Chemical class 0.000 title abstract 3
- QAQJMLQRFWZOBN-LAUBAEHRSA-N L-ascorbyl-6-palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@H]1OC(=O)C(O)=C1O QAQJMLQRFWZOBN-LAUBAEHRSA-N 0.000 title abstract 2
- 235000010385 ascorbyl palmitate Nutrition 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229940094443 oxytocics prostaglandins Drugs 0.000 title 1
- 239000003381 stabilizer Substances 0.000 title 1
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 2
- 235000000072 L-ascorbyl-6-palmitate Nutrition 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 229960005070 ascorbic acid Drugs 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 239000007903 gelatin capsule Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 229920000136 polysorbate Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/195,575 US4310543A (en) | 1980-10-09 | 1980-10-09 | Prostaglandin compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL63960A0 IL63960A0 (en) | 1981-12-31 |
| IL63960A true IL63960A (en) | 1985-05-31 |
Family
ID=22721933
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL63960A IL63960A (en) | 1980-10-09 | 1981-09-28 | Pharmaceutical compositions comprising prostaglandins and ascorbyl palmitate as stabilizer |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4310543A (https=) |
| EP (1) | EP0049852B1 (https=) |
| JP (1) | JPS5793911A (https=) |
| AT (1) | ATE14981T1 (https=) |
| AU (1) | AU547175B2 (https=) |
| CA (1) | CA1176567A (https=) |
| DE (1) | DE3171928D1 (https=) |
| DK (1) | DK442881A (https=) |
| IE (1) | IE51637B1 (https=) |
| IL (1) | IL63960A (https=) |
| NZ (1) | NZ198533A (https=) |
| PH (1) | PH17073A (https=) |
| ZA (1) | ZA816852B (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1695783A (en) * | 1982-07-19 | 1984-01-26 | Syntex (U.S.A.) Inc. | Encapsulated pge type compositions |
| US4431833A (en) * | 1982-12-27 | 1984-02-14 | American Cyanamid Company | Prostaglandin and hydroxylated fatty acid ester formulations |
| FR2549371B1 (fr) * | 1983-07-20 | 1985-09-13 | Sanofi Sa | Nouvelle composition pharmaceutique contenant de l'acide valproique ou un de ses sels |
| KR850700213A (ko) * | 1984-02-08 | 1985-12-26 | 제이.데스몬드 다비스 | 아세트 아미노펜 젤라틴 캡슐 |
| DE3438830A1 (de) * | 1984-10-23 | 1986-04-30 | Rentschler Arzneimittel | Nifedipin enthaltende darreichungsform und verfahren zu ihrer herstellung |
| NO882653D0 (no) * | 1988-06-15 | 1988-06-15 | Apothekernes Lab | Doseringsform. |
| US5208256A (en) * | 1990-05-22 | 1993-05-04 | R-Tech Ueno, Ltd. | Treatment of ocular hypertension with a synergistic combination for ocular administration |
| GB2281697A (en) * | 1993-09-14 | 1995-03-15 | Euro Celtique Sa | Laxative compositions in capsules |
| US6180666B1 (en) | 1997-09-05 | 2001-01-30 | Anmax, Inc. | Use of gallic acid esters to increase bioavailability of orally administered pharmaceutical compounds |
| US5962522A (en) * | 1997-09-05 | 1999-10-05 | Avmax, Inc. | Propyl gallate to increase bioavailability of orally administered pharmaceutical compounds |
| WO2001003695A1 (en) * | 1999-07-13 | 2001-01-18 | Avmax, Inc. | Improvement of bioavailability with vitamin c fatty acid esters |
| KR100649860B1 (ko) * | 2000-09-01 | 2006-11-24 | 주식회사종근당 | 알프로스타딜 경점막 및 경피흡수제제 |
| CA2422031C (en) * | 2000-09-13 | 2011-11-15 | Santen Pharmaceutical Co., Ltd. | Ophthalmic solutions comprising difluoroprostaglandin f2 alpha |
| WO2005011704A1 (ja) * | 2003-07-31 | 2005-02-10 | Santen Pharmaceutical Co., Ltd. | プロスタグランジン含有製品 |
| KR101152470B1 (ko) | 2003-08-13 | 2012-06-01 | 바이오콘 리미티드 | 치료제용 마이크로-입자 지방산 염 고형 투약 제형 |
| EP1675548A4 (en) * | 2003-09-25 | 2008-08-13 | Activbiotics Inc | RIFALAZIL FORMULATIONS |
| US9993558B2 (en) | 2004-10-01 | 2018-06-12 | Ramscor, Inc. | Sustained release eye drop formulations |
| US8541413B2 (en) * | 2004-10-01 | 2013-09-24 | Ramscor, Inc. | Sustained release eye drop formulations |
| CN102526064A (zh) * | 2004-12-09 | 2012-07-04 | 参天制药株式会社 | 含有分子内具有氟原子的前列腺素的制品 |
| WO2006068266A1 (ja) * | 2004-12-24 | 2006-06-29 | Santen Pharmaceutical Co., Ltd. | プロスタグランジンＦ２ａ誘導体含有製品 |
| CA2651159A1 (en) * | 2006-04-06 | 2007-10-18 | Activbiotics Pharma Llc | Pharmaceutical compositions and uses thereof |
| EP2327398A3 (en) | 2007-07-19 | 2014-05-21 | R-Tech Ueno, Ltd. | Pharmaceutical composition comprising 11-deoxy-prostaglandin compound and method for stabilizing the compound |
| EP2214635A1 (en) * | 2007-10-19 | 2010-08-11 | Purdue Research Foundation | Solid formulations of crystalline compounds |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2889252A (en) * | 1956-05-14 | 1959-06-02 | American Cyanamid Co | Gelatin capsule containing hexylresorcinol and a lower polyalkylene glycol |
| ZA721937B (en) * | 1971-10-22 | 1972-12-27 | Upjohn Co | Pharmaceutical preparations and uses thereof |
| CA1043259A (en) * | 1972-12-08 | 1978-11-28 | Geoffrey F. Thompson | Medicament preparations and vehicles therefor |
| US3932634A (en) * | 1973-06-28 | 1976-01-13 | Pfizer Inc. | High potency vitamin water dispersible formulations |
| US4052446A (en) * | 1973-08-06 | 1977-10-04 | Hoffmann-La Roche Inc. | 11,16-substituted prostaglandins |
| JPS6019734B2 (ja) * | 1977-05-12 | 1985-05-17 | 三共株式会社 | 安定なプロスタグランジンｅ類製剤の製法 |
| JPS6046094B2 (ja) * | 1977-06-01 | 1985-10-14 | 科研製薬株式会社 | 安定化されたプロスタグランジンｅ類粉末製剤 |
| FI790043A7 (fi) * | 1978-01-17 | 1979-07-18 | Sandoz Ag | Prostaglandiner innehaollande terapeutisk sammansaettning |
-
1980
- 1980-10-09 US US06/195,575 patent/US4310543A/en not_active Expired - Lifetime
-
1981
- 1981-09-09 CA CA000385446A patent/CA1176567A/en not_active Expired
- 1981-09-11 PH PH26191A patent/PH17073A/en unknown
- 1981-09-28 IL IL63960A patent/IL63960A/xx unknown
- 1981-10-02 NZ NZ198533A patent/NZ198533A/en unknown
- 1981-10-02 ZA ZA816852A patent/ZA816852B/xx unknown
- 1981-10-06 EP EP81107988A patent/EP0049852B1/de not_active Expired
- 1981-10-06 AT AT81107988T patent/ATE14981T1/de active
- 1981-10-06 AU AU76068/81A patent/AU547175B2/en not_active Ceased
- 1981-10-06 DE DE8181107988T patent/DE3171928D1/de not_active Expired
- 1981-10-06 DK DK442881A patent/DK442881A/da not_active Application Discontinuation
- 1981-10-08 IE IE2354/81A patent/IE51637B1/en unknown
- 1981-10-08 JP JP56159562A patent/JPS5793911A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| AU7606881A (en) | 1982-04-22 |
| EP0049852A3 (en) | 1983-01-26 |
| ATE14981T1 (de) | 1985-09-15 |
| JPH032848B2 (https=) | 1991-01-17 |
| JPS5793911A (en) | 1982-06-11 |
| EP0049852A2 (de) | 1982-04-21 |
| US4310543A (en) | 1982-01-12 |
| PH17073A (en) | 1984-05-24 |
| DK442881A (da) | 1982-04-10 |
| IE812354L (en) | 1982-04-09 |
| ZA816852B (en) | 1982-09-29 |
| EP0049852B1 (de) | 1985-08-21 |
| AU547175B2 (en) | 1985-10-10 |
| IE51637B1 (en) | 1987-01-21 |
| CA1176567A (en) | 1984-10-23 |
| IL63960A0 (en) | 1981-12-31 |
| NZ198533A (en) | 1984-12-14 |
| DE3171928D1 (en) | 1985-09-26 |
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