IL60877A - Propenylamines,their production and pharmaceutical compositions containing them - Google Patents

Propenylamines,their production and pharmaceutical compositions containing them

Info

Publication number
IL60877A
IL60877A IL60877A IL6087780A IL60877A IL 60877 A IL60877 A IL 60877A IL 60877 A IL60877 A IL 60877A IL 6087780 A IL6087780 A IL 6087780A IL 60877 A IL60877 A IL 60877A
Authority
IL
Israel
Prior art keywords
production
pharmaceutical compositions
compositions containing
propenylamines
formula
Prior art date
Application number
IL60877A
Other languages
English (en)
Other versions
IL60877A0 (en
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4328536&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL60877(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IL60877A0 publication Critical patent/IL60877A0/xx
Publication of IL60877A publication Critical patent/IL60877A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/04—Acyclic alcohols with carbon-to-carbon triple bonds
    • C07C33/048—Acyclic alcohols with carbon-to-carbon triple bonds with double and triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/05—Alcohols containing rings other than six-membered aromatic rings
    • C07C33/12—Alcohols containing rings other than six-membered aromatic rings containing five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/12—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with only hydrogen atoms attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/08—Hydrogen atoms or radicals containing only hydrogen and carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58—Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
  • Radiation-Therapy Devices (AREA)
  • Replacement Of Web Rolls (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IL60877A 1979-08-22 1980-08-19 Propenylamines,their production and pharmaceutical compositions containing them IL60877A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH765679 1979-08-22

Publications (2)

Publication Number Publication Date
IL60877A0 IL60877A0 (en) 1980-10-26
IL60877A true IL60877A (en) 1984-08-31

Family

ID=4328536

Family Applications (1)

Application Number Title Priority Date Filing Date
IL60877A IL60877A (en) 1979-08-22 1980-08-19 Propenylamines,their production and pharmaceutical compositions containing them

Country Status (24)

Country Link
US (1) US4755534A (es)
EP (1) EP0024587B1 (es)
JP (2) JPS5632440A (es)
AT (1) ATE10272T1 (es)
AU (1) AU538928B2 (es)
CA (1) CA1157023A (es)
CY (1) CY1410A (es)
DE (3) DE3069633D1 (es)
DK (1) DK153470C (es)
ES (1) ES8105694A1 (es)
FI (1) FI65775C (es)
HK (1) HK21588A (es)
IE (1) IE50878B1 (es)
IL (1) IL60877A (es)
KE (1) KE3775A (es)
LU (1) LU88343I2 (es)
MY (1) MY8600181A (es)
NL (1) NL930136I2 (es)
NZ (1) NZ194714A (es)
PH (1) PH22166A (es)
PT (1) PT71717B (es)
SG (1) SG89287G (es)
YU (1) YU41513B (es)
ZA (1) ZA805185B (es)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
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US5132459A (en) * 1979-08-22 1992-07-21 Sandoz Ltd. Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals
CH653028A5 (de) * 1982-02-03 1985-12-13 Sandoz Ag Benzthiophenallylamin-verbindungen und verfahren zu ihrer herstellung.
FR2526423B1 (fr) * 1982-05-07 1987-07-10 Sandoz Sa Nouvelles amines insaturees, leur preparation et leur utilisation comme medicaments
JPS6145A (ja) * 1984-06-09 1986-01-06 Kaken Pharmaceut Co Ltd Ｎ‐（４‐ｔｅｒｔ‐ブチルベンジル）‐Ｎ‐メチル‐１‐ナフチルメチルアミンおよびそれを有効成分とする抗真菌剤
EP0191269B1 (en) * 1984-11-22 1991-03-06 Sandoz Ag Novel homopropargylamines
CH672311A5 (es) * 1985-09-14 1989-11-15 Sandoz Ag
HU211997B (en) * 1986-01-29 1996-01-29 Sandoz Ag Process to prepare n-methyl-n-(1-naphtyl-methyl)-4-(2-phenyl-propyl)-benzylamine and pharmaceutical compns. contg. it
US4751245A (en) * 1986-06-25 1988-06-14 E. R. Squibb & Sons, Inc. Antifungal derivatives of N-(6,6-dimethyl-2-hepten-4-ynyl)-1-naphthalenemethanamine and method of using same
EP0254677A1 (en) * 1986-07-08 1988-01-27 Sandoz Ag Antimycotic 6-phenyl-2-hexen-4-ynamines
JPS63238060A (ja) * 1987-03-26 1988-10-04 Maruho Kk キノリン誘導体
CA1327795C (en) * 1987-08-14 1994-03-15 Jules Freedman Antidepressants which are aryloxy inadanamines
US5149714A (en) * 1987-08-14 1992-09-22 Merrell Dow Pharmaceuticals Inc. Antidepressants
NZ227042A (en) 1987-11-27 1991-05-28 Banyu Pharma Co Ltd Substituted alkylamine derivatives and pharmaceutical compositions
US5234946A (en) * 1987-11-27 1993-08-10 Banyu Pharmaceutical Co., Ltd. Substituted alkylamine derivatives
EP0363326A3 (en) * 1988-10-07 1991-10-09 Sandoz Ag Fungicidal amines
EP0378457B1 (en) * 1989-01-12 1994-08-03 Sumitomo Chemical Company Limited Aromatic allyl amine thermosetting resin composition
JP3116364B2 (ja) * 1989-10-02 2000-12-11 萬有製薬株式会社 エンイン誘導体の製造法
FR2673537B1 (fr) 1991-03-08 1993-06-11 Oreal Utilisation d'agents de penetration hydrophiles dans les compositions dermatologiques pour le traitement des onychomycoses, et compositions correspondantes.
HU223343B1 (hu) * 1991-05-20 2004-06-28 Novartis Ag. Allil-amin-származékot tartalmazó gyógyászati készítmények és eljárás azok előállítására
HU219480B (hu) * 1991-05-23 2001-04-28 Novartis Ag. Eljárás gombás körömmegbetegségek ellen helyileg alkalmazható, allil-amin-származékot tartalmazó gyógyászati készítmények előállítására
GB9111611D0 (en) * 1991-05-30 1991-07-24 Sandoz Ltd Liposomes
JPH04138020U (ja) * 1991-06-14 1992-12-24 日立機材株式会社 バケツトエレベータ
GB9513750D0 (en) * 1995-07-06 1995-09-06 Sandoz Ltd Use of allylamines
NZ280065A (en) * 1995-09-20 1998-04-27 Apotex Inc Preparation of n-alkyl-n-(1-naphthylmethyl)alk-2-en-4-ynylamine derivatives
US6075056A (en) * 1997-10-03 2000-06-13 Penederm, Inc. Antifungal/steroid topical compositions
SK5202000A3 (en) 2000-04-07 2001-12-03 Slovakofarma As Method for the preparation of (e)-n-(6,6-dimethyl-2-hepten-4- inyl)-n-methyl-1-naphthalenemethylamine (terbinaphin)
BR0111654A (pt) * 2000-06-09 2003-05-20 Bayer Cropscience Sa Processo de preparação de compostos pesticidas
IL137364A (en) * 2000-07-18 2005-08-31 Chemagis Ltd Process for the preparation of 6,6-dimethylhept-1-en-4-yn-3-ol
GB0103046D0 (en) 2001-02-07 2001-03-21 Novartis Ag Organic Compounds
US7244703B2 (en) * 2001-06-22 2007-07-17 Bentley Pharmaceuticals, Inc. Pharmaceutical compositions and methods for peptide treatment
KR100459275B1 (ko) 2001-12-28 2004-12-03 주식회사유한양행 터비나핀 또는 그의 염산염의 제조방법
BG65097B1 (bg) * 2002-03-15 2007-02-28 Richter Gedeon Vegyeszeti Gyar Rt. Метод за получаване на заместено производно на алиламин и на съответните му соли
US8404751B2 (en) 2002-09-27 2013-03-26 Hallux, Inc. Subunguicide, and method for treating onychomycosis
JP4540667B2 (ja) 2003-03-21 2010-09-08 ネクスメツド・ホールデイングス・インコーポレイテツド 抗真菌性ネイルコート
US20050197512A1 (en) * 2003-08-29 2005-09-08 Ulrich Beutler Purification process
GB0320312D0 (en) * 2003-08-29 2003-10-01 Novartis Ag Purification process
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US7112561B2 (en) 2003-12-08 2006-09-26 Bentley Pharmaceuticals, Inc. Pharmaceutical compositions and methods for insulin treatment
ES2245596B1 (es) * 2004-06-10 2007-07-01 Ercros Industrial, S.A. Procedimiento para la obtencion de clorhidrato de terbinafina.
US20060004230A1 (en) * 2004-06-30 2006-01-05 Joseph Kaspi Process for the preparation of terbinafine and salts thereof
CA2570245A1 (en) * 2004-07-02 2006-01-12 Warner-Lambert Company Llc Compositions and methods for treating pathological infections
US7740875B2 (en) * 2004-10-08 2010-06-22 Mediquest Therapeutics, Inc. Organo-gel formulations for therapeutic applications
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CN1293037C (zh) * 2004-11-03 2007-01-03 浙江海正药业股份有限公司 一种制备特比萘芬盐酸盐的方法
JP2009502258A (ja) * 2005-07-21 2009-01-29 ノミール・メディカル・テクノロジーズ・インコーポレーテッド 標的部位の生物学的汚染物質のレベルを下げる方法
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US20080176908A1 (en) * 2007-01-18 2008-07-24 Mcanally Weylan R Method of using squalene monooxygenase inhibitors to treat acne
US20090082469A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched terbinafine
JP2011529038A (ja) * 2008-07-23 2011-12-01 ターゲッティド デリバリー テクノロジーズ リミテッド 真菌感染症の処置のための局所抗真菌製剤の投与方法
EP2730271B1 (en) 2012-11-11 2018-01-24 Symrise AG Aqeuous compositions
US8697753B1 (en) 2013-02-07 2014-04-15 Polichem Sa Method of treating onychomycosis
ES2701758T3 (es) 2013-02-27 2019-02-25 Symrise Ag Extracto de jengibre para la protección de citoblastos
CN105377355A (zh) 2013-03-14 2016-03-02 拇趾公司 治疗甲单元的感染、疾病或病症的方法
EP2862852B1 (en) 2013-10-18 2018-07-04 Symrise AG Urea derivatives for the protection of stem cells
EP2921157B1 (en) 2014-03-18 2017-08-16 Symrise AG Coated titanium dioxide to reduce whitening effect on skin
ES2819207T3 (es) 2014-04-29 2021-04-15 Symrise Ag Mezclas activas
EP3045161A1 (en) 2015-01-18 2016-07-20 Symrise AG Active compositions comprising 1,2-hexanediol and 1,2-octanediol
CN104725240B (zh) * 2015-02-12 2017-05-24 吉林修正药业新药开发有限公司 一种盐酸特比萘芬z型异构体的制备方法
CN108084125B (zh) * 2016-11-23 2020-08-18 华东理工大学 苯并杂环烷基胺类化合物及其用途
CN114727689B (zh) 2019-11-12 2023-11-03 Ykk株式会社 拉链

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BE623609A (es) * 1961-10-27
DE2716943C2 (de) * 1976-04-28 1986-08-14 Sandoz-Patent-GmbH, 7850 Lörrach N-(3-Phenyl-2-propenyl)-N-(1-naphthylmethyl)-amine, ihre Verwendung und Herstellung
DE2862103D1 (en) * 1977-08-19 1982-11-18 Sandoz Ag Propenyl amines, processes for their production and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
CY1410A (en) 1988-04-22
FI802583A (fi) 1981-02-23
JPH0415216B2 (es) 1992-03-17
YU209680A (en) 1983-10-31
ES494408A0 (es) 1981-06-16
LU88343I2 (fr) 1994-05-04
IL60877A0 (en) 1980-10-26
JPS5632440A (en) 1981-04-01
DK153470B (da) 1988-07-18
MY8600181A (en) 1986-12-31
ES8105694A1 (es) 1981-06-16
AU6159280A (en) 1981-04-16
DE19975055I1 (de) 2000-01-27
DK153470C (da) 1988-11-28
SG89287G (en) 1988-09-30
ATE10272T1 (de) 1984-11-15
IE50878B1 (en) 1986-08-06
NZ194714A (en) 1984-11-09
FI65775C (fi) 1984-07-10
CA1157023A (en) 1983-11-15
US4755534A (en) 1988-07-05
FI65775B (fi) 1984-03-30
ZA805185B (en) 1982-03-31
DK357980A (da) 1981-02-23
DE3069633D1 (en) 1984-12-20
NL930136I2 (nl) 1998-10-01
NL930136I1 (nl) 1993-11-01
PH22166A (en) 1988-06-28
PT71717B (en) 1981-09-24
IE801770L (en) 1981-02-22
KE3775A (en) 1987-11-27
EP0024587B1 (en) 1984-11-14
JPS6342612B2 (es) 1988-08-24
PT71717A (en) 1980-09-01
EP0024587A1 (en) 1981-03-11
AU538928B2 (en) 1984-09-06
JPS63313753A (ja) 1988-12-21
YU41513B (en) 1987-08-31
HK21588A (en) 1988-03-31
DE19375084I2 (de) 2000-11-16

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Legal Events

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