IL60517A - 2,4,6-triiodoisophthalic acid derivatives,process for the preparation thereof and x-ray contrast preparations - Google Patents

2,4,6-triiodoisophthalic acid derivatives,process for the preparation thereof and x-ray contrast preparations

Info

Publication number
IL60517A
IL60517A IL60517A IL6051780A IL60517A IL 60517 A IL60517 A IL 60517A IL 60517 A IL60517 A IL 60517A IL 6051780 A IL6051780 A IL 6051780A IL 60517 A IL60517 A IL 60517A
Authority
IL
Israel
Prior art keywords
alkyl
groups
ray contrast
preparation
hydrogen
Prior art date
Application number
IL60517A
Other languages
English (en)
Other versions
IL60517A0 (en
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL60517A0 publication Critical patent/IL60517A0/xx
Publication of IL60517A publication Critical patent/IL60517A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
IL60517A 1979-07-12 1980-07-08 2,4,6-triiodoisophthalic acid derivatives,process for the preparation thereof and x-ray contrast preparations IL60517A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792928417 DE2928417A1 (de) 1979-07-12 1979-07-12 Trijodierte basen

Publications (2)

Publication Number Publication Date
IL60517A0 IL60517A0 (en) 1980-09-16
IL60517A true IL60517A (en) 1984-06-29

Family

ID=6075678

Family Applications (1)

Application Number Title Priority Date Filing Date
IL60517A IL60517A (en) 1979-07-12 1980-07-08 2,4,6-triiodoisophthalic acid derivatives,process for the preparation thereof and x-ray contrast preparations

Country Status (21)

Country Link
US (1) US4283381A (xx)
EP (1) EP0022744B1 (xx)
JP (1) JPS5659717A (xx)
AT (1) ATE2834T1 (xx)
AU (1) AU536426B2 (xx)
CA (1) CA1129438A (xx)
CS (1) CS214834B2 (xx)
DE (2) DE2928417A1 (xx)
DK (1) DK154501C (xx)
EG (1) EG14884A (xx)
ES (2) ES8104792A1 (xx)
FI (1) FI68042C (xx)
GR (1) GR69303B (xx)
HU (1) HU182154B (xx)
IE (1) IE50064B1 (xx)
IL (1) IL60517A (xx)
NO (1) NO150719C (xx)
PH (1) PH16651A (xx)
PT (1) PT71547A (xx)
YU (1) YU177980A (xx)
ZA (1) ZA804192B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3038853A1 (de) 1980-10-10 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue n-hydroxy-alkylierte dicarbonsaeure-bis-(3,5-dicarbamoyl-2,4,6-trijodanilide), deren herstellung und diese enthaltende roentgenkonstrastmittel (ii)
DE3150917A1 (de) * 1981-12-18 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen "2-amino-1-(1,3-dioxolan-4-yl)-ethanol-verbindungen, deren herstellung und verwendung zur weiterverarbeitung"
FR2541676A1 (fr) * 1983-02-25 1984-08-31 Guerbet Sa Composes non-ioniques a structures benzenique iodee ou bromee et produits opacifiants en contenant
GB8906130D0 (en) * 1989-03-17 1989-05-04 Nycomed As Compositions
US5232685A (en) * 1989-11-03 1993-08-03 Schering Aktiengesellschaft Nonionic x-ray contrast medium with high iodine content
US5614638A (en) * 1989-11-29 1997-03-25 Bracco International B.V. Nonionic radiographic contrast agents
CA2029830A1 (en) * 1989-11-29 1991-05-30 Ramachandran S. Ranganathan Nonionic radiographic contrast agents
GB9020091D0 (en) * 1990-09-14 1990-10-24 Nycomed As Contrast media
US5278311A (en) * 1992-06-05 1994-01-11 E. R. Squibb & Sons, Inc. Nonionic radiographic contrast agents
ATE181547T1 (de) * 1994-09-22 1999-07-15 Guerbet Sa Iodo-verbindungen, ihre herstellung und verwendung als kontrastmittel für röntgen- radiologie
IT1299202B1 (it) * 1998-05-08 2000-02-29 Dibra Spa Processo per la preparazione della s-n,n'-bis (2-idrossi-1- (idrossimetil)etil) -5-((2-idrossi-1-ossopropil)ammino)-2,4,6-triiodo
IT1312569B1 (it) * 1999-05-21 2002-04-22 Raffaele Ansovini Uso dell'enzima gssg reduttasi per il trattamento terapeutico e laprofilassi di pazienti infettati da hiv.
US7790141B2 (en) * 2003-08-11 2010-09-07 Pathak Holdings, Llc Radio-opaque compounds, compositions containing same and methods of their synthesis and use
CN101654417B (zh) * 2009-09-01 2012-06-20 江苏省原子医学研究所 X线造影剂碘佛醇中间体的制备方法
CN105461581A (zh) * 2015-11-17 2016-04-06 浙江海洲制药有限公司 碘帕醇杂质a和杂质b的合成方法
CN115806498A (zh) * 2021-09-15 2023-03-17 大道隆达（北京）医药科技发展有限公司 5-氯乙酰胺基-2,4,6-三碘异酞酰氯的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2776241A (en) * 1952-08-06 1957-01-01 Schering Ag Injectable x-ray contrast agents comprising salts of n-acyl derivatives of 2, 4, 6-triiodo-3-aminobenzoic acid
US3178473A (en) * 1962-03-02 1965-04-13 Nyegaard & Co As Process for the n-alkylation of acyl anilides halogen substituted in the nucleus
US4021481A (en) * 1969-06-27 1977-05-03 Nyegaard & Co. A/S Amido derivatives of 2,4,6-triiodobenzoic acids containing at least one N-hydroxyalkyl and at least two hydroxyl groups
ES381202A1 (es) * 1969-06-27 1973-04-16 Nyegaard & Co As Un procedimiento para la preparacion de agentes de contras-te de rayos x.
BE795555A (fr) * 1972-02-16 1973-08-16 Schering Ag Amides de triiodo-isophtaloyl-monoamino-acide, leur procede de preparation et leur utilisation
GB1548594A (en) * 1976-06-11 1979-07-18 Nyegaard & Co As Triiodoisophthalic acid amides
US4192859A (en) * 1978-09-29 1980-03-11 E. R. Squibb & Sons, Inc. Contrast media containing liposomes as carriers

Also Published As

Publication number Publication date
PH16651A (en) 1983-12-06
ZA804192B (en) 1981-07-29
EP0022744A3 (en) 1981-03-11
FI68042B (fi) 1985-03-29
IE50064B1 (en) 1986-02-05
NO802102L (no) 1981-01-13
ES493301A0 (es) 1981-05-16
EG14884A (en) 1985-06-30
YU177980A (en) 1983-12-31
HU182154B (en) 1983-12-28
DK300680A (da) 1981-01-13
IL60517A0 (en) 1980-09-16
ES8104791A1 (es) 1981-05-16
AU6029480A (en) 1981-01-15
EP0022744A2 (de) 1981-01-21
NO150719B (no) 1984-08-27
PT71547A (en) 1980-08-01
ATE2834T1 (de) 1983-04-15
DK154501C (da) 1989-04-10
DK154501B (da) 1988-11-21
CA1129438A (en) 1982-08-10
ES493302A0 (es) 1981-05-16
JPS5659717A (en) 1981-05-23
CS214834B2 (en) 1982-06-25
NO150719C (no) 1984-12-05
AU536426B2 (en) 1984-05-10
US4283381A (en) 1981-08-11
FI802215A (fi) 1981-01-13
GR69303B (xx) 1982-05-14
DE3062428D1 (en) 1983-04-28
ES8104792A1 (es) 1981-05-16
FI68042C (fi) 1985-07-10
DE2928417A1 (de) 1981-01-29
IE801441L (en) 1981-01-12
EP0022744B1 (de) 1983-03-23

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