IL60245A - Oxopiperazinyl analogs of enkephalin,their preparation and pharmaceutical compositions comprising them - Google Patents

Oxopiperazinyl analogs of enkephalin,their preparation and pharmaceutical compositions comprising them

Info

Publication number
IL60245A
IL60245A IL60245A IL6024580A IL60245A IL 60245 A IL60245 A IL 60245A IL 60245 A IL60245 A IL 60245A IL 6024580 A IL6024580 A IL 6024580A IL 60245 A IL60245 A IL 60245A
Authority
IL
Israel
Prior art keywords
oxopiperazinyl
enkephalin
analogs
preparation
pharmaceutical compositions
Prior art date
Application number
IL60245A
Other languages
English (en)
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Priority to IL7078980A priority Critical patent/IL70789A/xx
Priority to IL7078880A priority patent/IL70788A/xx
Priority to IL70788A priority patent/IL70788A0/xx
Priority to IL70789A priority patent/IL70789A0/xx
Publication of IL60245A publication Critical patent/IL60245A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IL60245A 1979-06-21 1980-06-06 Oxopiperazinyl analogs of enkephalin,their preparation and pharmaceutical compositions comprising them IL60245A (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IL7078980A IL70789A (en) 1979-06-21 1980-06-06 Piperazine derivatives and process for their production
IL7078880A IL70788A (en) 1979-06-21 1980-06-06 Piperazine derivatives and process for their production
IL70788A IL70788A0 (en) 1979-06-21 1984-01-26 Novel piperazine derivatives and process for their production
IL70789A IL70789A0 (en) 1979-06-21 1984-01-26 Novel piperazine derivatives and process for their production

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5095079A 1979-06-21 1979-06-21
US06/130,431 US4341698A (en) 1979-06-21 1980-03-14 Enkaphalin derivatives
AU91877/82A AU559278B2 (en) 1979-06-21 1982-12-24 Piperazines

Publications (1)

Publication Number Publication Date
IL60245A true IL60245A (en) 1985-08-30

Family

ID=36764304

Family Applications (1)

Application Number Title Priority Date Filing Date
IL60245A IL60245A (en) 1979-06-21 1980-06-06 Oxopiperazinyl analogs of enkephalin,their preparation and pharmaceutical compositions comprising them

Country Status (17)

Country Link
US (1) US4341698A (xx)
AU (1) AU559278B2 (xx)
CA (1) CA1161838A (xx)
CH (2) CH645363A5 (xx)
DE (1) DE3022401A1 (xx)
DK (1) DK265780A (xx)
ES (1) ES492566A0 (xx)
FR (2) FR2459236A1 (xx)
GB (3) GB2051821B (xx)
IE (1) IE49834B1 (xx)
IL (1) IL60245A (xx)
IT (1) IT1148277B (xx)
NL (1) NL8003580A (xx)
NO (1) NO801855L (xx)
NZ (1) NZ193934A (xx)
PH (1) PH19222A (xx)
SE (3) SE447250B (xx)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6369080B2 (en) 1996-10-11 2002-04-09 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6262047B1 (en) 1996-10-11 2001-07-17 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6194435B1 (en) 1996-10-11 2001-02-27 Cor Therapeutics, Inc. Lactams as selective factor Xa inhibitors
US6063794A (en) 1996-10-11 2000-05-16 Cor Therapeutics Inc. Selective factor Xa inhibitors
AU6896298A (en) 1997-04-14 1998-11-11 Cor Therapeutics, Inc. Selective factor xa inhibitors
US6133256A (en) * 1997-04-14 2000-10-17 Cor Therapeutics Inc Selective factor Xa inhibitors
AU6896398A (en) 1997-04-14 1998-11-11 Cor Therapeutics, Inc. Selective factor xa inhibitors
US6228854B1 (en) 1997-08-11 2001-05-08 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6218382B1 (en) 1997-08-11 2001-04-17 Cor Therapeutics, Inc Selective factor Xa inhibitors
US6333321B1 (en) 1997-08-11 2001-12-25 Cor Therapeutics, Inc. Selective factor Xa inhibitors
JP2008534504A (ja) 2005-03-22 2008-08-28 アゼヴァン ファーマスーティカルズ，インコーポレイテッド 月経前障害を治療するためのβラクタミルアルカン酸
SI1910346T1 (sl) 2005-07-19 2019-08-30 Azevan Pharmaceuticals, Inc. Antagonist beta-laktamil fenilalalina, cisteina in serin vasopresina
EA200802060A1 (ru) * 2006-03-30 2009-10-30 Палатин Текнолоджиз, Инк. Суррогаты аминокислот для пептидных конструктов
US8580746B2 (en) 2006-03-30 2013-11-12 Palatin Technologies, Inc. Amide linkage cyclic natriuretic peptide constructs
WO2007115175A2 (en) * 2006-03-30 2007-10-11 Palatin Technologies, Inc. Cyclic natriuretic peptide constructs
US8114844B2 (en) * 2006-03-30 2012-02-14 Palatin Technologies, Inc. Linear and cyclic melanocortin receptor-specific peptidomimetics
US7964181B2 (en) * 2006-03-30 2011-06-21 Palatin Technologies, Inc. Amino acid surrogates for peptidic constructs
US7795221B2 (en) * 2006-03-30 2010-09-14 Palatin Technologies, Inc. Linear natriuretic peptide constructs
NZ577114A (en) * 2006-12-19 2011-12-22 Hoffmann La Roche Heteroaryl pyrrolidinyl and piperidinyl ketone derivatives
CA2728373A1 (en) * 2008-06-18 2009-12-23 F.Hoffmann-La Roche Ag Aryl ketone as mri
US9376424B2 (en) 2010-07-01 2016-06-28 Azevan Pharmaceuticals, Inc. Methods for treating post traumatic stress disorder
US9802925B2 (en) 2014-03-28 2017-10-31 Azevan Pharmaceuticals, Inc. Compositions and methods for treating neurodegenerative diseases
AU2018333051B2 (en) 2017-09-15 2024-03-21 Azevan Pharmaceuticals, Inc. Compositions and methods for treating brain injury

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2604845A1 (de) * 1976-02-07 1977-08-18 Knoll Ag Neue piperazinderivate
US4254107A (en) * 1979-11-27 1981-03-03 Merck & Co., Inc. Long-lasting agonists of enkephalin

Also Published As

Publication number Publication date
CH648835A5 (de) 1985-04-15
ES8105720A1 (es) 1981-06-16
SE447250B (sv) 1986-11-03
NZ193934A (en) 1983-02-15
CA1161838A (en) 1984-02-07
GB2132605A (en) 1984-07-11
GB2132605B (en) 1985-01-03
AU559278B2 (en) 1987-03-05
IT1148277B (it) 1986-11-26
FR2459236B1 (xx) 1984-01-06
IE801152L (en) 1980-12-21
FR2473042A1 (fr) 1981-07-10
FR2459236A1 (fr) 1981-01-09
SE460540B (sv) 1989-10-23
IT8049032A0 (it) 1980-06-20
FR2473042B1 (xx) 1983-07-01
NL8003580A (nl) 1980-12-23
GB2106515B (en) 1983-11-23
SE460541B (sv) 1989-10-23
ES492566A0 (es) 1981-06-16
US4341698A (en) 1982-07-27
GB2051821A (en) 1981-01-21
CH645363A5 (de) 1984-09-28
DE3022401A1 (de) 1981-01-08
SE8500877D0 (sv) 1985-02-22
GB2106515A (en) 1983-04-13
AU9187782A (en) 1983-04-21
GB2051821B (en) 1983-04-27
NO801855L (no) 1980-12-22
SE8500878D0 (sv) 1985-02-22
PH19222A (en) 1986-02-12
SE8500877L (sv) 1985-02-22
IE49834B1 (en) 1985-12-25
DK265780A (da) 1980-12-22
SE8004254L (sv) 1980-12-22

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