IL58256A - N-pyrrolyl-pyridazineamines,process for their manufacture and antihypertensive compositions containing them - Google Patents

N-pyrrolyl-pyridazineamines,process for their manufacture and antihypertensive compositions containing them

Info

Publication number
IL58256A
IL58256A IL58256A IL5825679A IL58256A IL 58256 A IL58256 A IL 58256A IL 58256 A IL58256 A IL 58256A IL 5825679 A IL5825679 A IL 5825679A IL 58256 A IL58256 A IL 58256A
Authority
IL
Israel
Prior art keywords
formula
lower alkyl
hydrogen
pyrrolyl
pyrrol
Prior art date
Application number
IL58256A
Other languages
English (en)
Other versions
IL58256A0 (en
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of IL58256A0 publication Critical patent/IL58256A0/xx
Publication of IL58256A publication Critical patent/IL58256A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30Phthalazines
    • C07D237/34Phthalazines with nitrogen atoms directly attached to carbon atoms of the nitrogen-containing ring, e.g. hydrazine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20Nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrrole Compounds (AREA)
IL58256A 1978-10-02 1979-09-17 N-pyrrolyl-pyridazineamines,process for their manufacture and antihypertensive compositions containing them IL58256A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7838898 1978-10-02

Publications (2)

Publication Number Publication Date
IL58256A0 IL58256A0 (en) 1979-12-30
IL58256A true IL58256A (en) 1984-02-29

Family

ID=10500040

Family Applications (1)

Application Number Title Priority Date Filing Date
IL58256A IL58256A (en) 1978-10-02 1979-09-17 N-pyrrolyl-pyridazineamines,process for their manufacture and antihypertensive compositions containing them

Country Status (15)

Country Link
EP (1) EP0009655B1 (de)
JP (1) JPS5569577A (de)
AT (1) ATE3294T1 (de)
AU (1) AU529482B2 (de)
CA (1) CA1144165A (de)
DE (1) DE2965377D1 (de)
DK (1) DK151803C (de)
ES (1) ES484616A1 (de)
FI (1) FI65998C (de)
GR (1) GR69856B (de)
IE (1) IE49017B1 (de)
IL (1) IL58256A (de)
NO (1) NO151620C (de)
YU (1) YU41886B (de)
ZA (1) ZA794923B (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD916552S1 (en) * 2019-07-26 2021-04-20 Spectrum Diversified Designs, Llc Trivet

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1150070B (it) * 1980-12-22 1986-12-10 Lepetit Spa Procedimento per preparare derivati n-pirrolipiridazinamminici
US5254622A (en) * 1988-12-09 1993-10-19 Asahi Kasei Kogyo Kabushiki Kaisha ABS resin compositions and molded articles thereof having improved coating performances
US7514436B2 (en) * 2003-07-30 2009-04-07 Xenon Pharmaceuticals Inc. Pyridazine derivatives and their use as therapeutic agents
CN101083982A (zh) 2004-09-20 2007-12-05 泽农医药公司 用于治疗硬脂酰CoA去饱和酶介导的疾病的杂环衍生物
AU2005329423A1 (en) 2004-09-20 2006-09-28 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
WO2006034441A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
JP4958786B2 (ja) 2004-09-20 2012-06-20 ゼノン・ファーマシューティカルズ・インコーポレイテッド 複素環誘導体および治療薬としてのそれらの使用
TW200626138A (en) 2004-09-20 2006-08-01 Xenon Pharmaceuticals Inc Heterocyclic derivatives and their use as therapeutic agents
AR051091A1 (es) 2004-09-20 2006-12-20 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
CN101083992A (zh) 2004-09-20 2007-12-05 泽农医药公司 抑制人硬脂酰CoA去饱和酶的哒嗪衍生物
MX2007015216A (es) 2005-06-03 2008-02-22 Xenon Pharmaceuticals Inc Derivados de aminotiazol y sus usos como agentes terapeuticos.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1168334A (en) * 1967-01-25 1969-10-22 Lepetit Spa New Pharmacologically Active Pyridazines
GB1378102A (en) * 1972-03-14 1974-12-18 Lepetit Spa Antihypertensive compositions
GB1408362A (en) * 1973-05-25 1975-10-01 Lepetit Spa 2-pyrrol-1-yl amino 4,5-dihydro-1-h-imidazole derivatives
AU477837B2 (en) * 1973-05-30 1974-12-05 I. S. F. Sp. A New anti-hypertensive compounds having a high therapeutic index and a long-term hypotensive effect
ES431009A1 (es) * 1974-05-09 1976-10-16 Isf Spa Procedimiento para la preparacion de derivados de 3-benci- lidenhidracino-6-aminopiridacina.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD916552S1 (en) * 2019-07-26 2021-04-20 Spectrum Diversified Designs, Llc Trivet

Also Published As

Publication number Publication date
DK400679A (da) 1980-04-03
AU5086679A (en) 1980-04-17
ATE3294T1 (de) 1983-05-15
DE2965377D1 (en) 1983-06-16
YU41886B (en) 1988-02-29
IE49017B1 (en) 1985-07-10
NO151620B (no) 1985-01-28
FI65998C (fi) 1984-08-10
IE791866L (en) 1980-04-02
AU529482B2 (en) 1983-06-09
GR69856B (de) 1982-07-19
ZA794923B (en) 1980-09-24
NO151620C (no) 1985-05-08
EP0009655A1 (de) 1980-04-16
DK151803C (da) 1988-06-13
EP0009655B1 (de) 1983-05-11
YU237479A (en) 1983-02-28
CA1144165A (en) 1983-04-05
DK151803B (da) 1988-01-04
ES484616A1 (es) 1980-05-16
NO793151L (no) 1980-04-08
FI65998B (fi) 1984-04-30
JPH0321553B2 (de) 1991-03-22
IL58256A0 (en) 1979-12-30
JPS5569577A (en) 1980-05-26
FI792832A (fi) 1980-04-03

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