IL56222A - 3-hydroxy(and methoxy)-17-substituted-8beta-ethyl-(and 8beta-methyl)-4,5alpha-epoxymorphinan-6-one compounds and their production - Google Patents

3-hydroxy(and methoxy)-17-substituted-8beta-ethyl-(and 8beta-methyl)-4,5alpha-epoxymorphinan-6-one compounds and their production

Info

Publication number
IL56222A
IL56222A IL56222A IL5622278A IL56222A IL 56222 A IL56222 A IL 56222A IL 56222 A IL56222 A IL 56222A IL 5622278 A IL5622278 A IL 5622278A IL 56222 A IL56222 A IL 56222A
Authority
IL
Israel
Prior art keywords
8beta
epoxymorphinan
5alpha
methoxy
hydroxy
Prior art date
Application number
IL56222A
Other languages
English (en)
Other versions
IL56222A0 (en
Original Assignee
Miles Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Lab filed Critical Miles Lab
Publication of IL56222A0 publication Critical patent/IL56222A0/xx
Publication of IL56222A publication Critical patent/IL56222A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL56222A 1978-02-10 1978-12-15 3-hydroxy(and methoxy)-17-substituted-8beta-ethyl-(and 8beta-methyl)-4,5alpha-epoxymorphinan-6-one compounds and their production IL56222A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87664078A 1978-02-10 1978-02-10
US91193978A 1978-06-02 1978-06-02

Publications (2)

Publication Number Publication Date
IL56222A0 IL56222A0 (en) 1979-03-12
IL56222A true IL56222A (en) 1981-11-30

Family

ID=27128411

Family Applications (1)

Application Number Title Priority Date Filing Date
IL56222A IL56222A (en) 1978-02-10 1978-12-15 3-hydroxy(and methoxy)-17-substituted-8beta-ethyl-(and 8beta-methyl)-4,5alpha-epoxymorphinan-6-one compounds and their production

Country Status (7)

Country Link
JP (1) JPS54117499A (de)
AU (1) AU507873B2 (de)
CA (1) CA1106369A (de)
DE (1) DE2900918A1 (de)
FR (1) FR2424277A1 (de)
GB (1) GB2014141B (de)
IL (1) IL56222A (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4272541A (en) * 1978-06-02 1981-06-09 Miles Laboratories, Inc. 7,8 and 7-8 Substituted 4,5α-epoxymorphinan-6-one compounds, and methods of treating pain and drug dependence with them
US4259329A (en) * 1979-10-17 1981-03-31 Miles Laboratories, Inc. 17-Cyclobutylmethyl-3-hydroxy-β-methyl-6-methylene morphinane, and methods of treating pain with them
US4275205A (en) * 1980-05-05 1981-06-23 Miles Laboratories, Inc. 7,7-Ditosyloxymethyl-4,5α-epoxy-morphinan-6-ols
JPS59500418A (ja) * 1982-03-16 1984-03-15 ザ　ロツクフエラ−　ユニバ−シテイ 胃腸能動作用障害を回復する方法
JPH0174251U (de) * 1987-11-02 1989-05-19
JPH043470U (de) * 1990-04-24 1992-01-13
US5194637A (en) * 1991-08-22 1993-03-16 Syracuse University Method and apparatus for synthesis of highly isomerically pure stereoisomers of glycidol derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1355143A (fr) * 1963-04-05 1964-03-13 Shionogi & Co Dérivés du morphinane et procédé de fabrication

Also Published As

Publication number Publication date
GB2014141B (en) 1982-09-15
FR2424277A1 (fr) 1979-11-23
JPS54117499A (en) 1979-09-12
FR2424277B1 (de) 1982-03-12
AU4409079A (en) 1979-08-16
JPS5757476B2 (de) 1982-12-04
AU507873B2 (en) 1980-02-28
GB2014141A (en) 1979-08-22
IL56222A0 (en) 1979-03-12
DE2900918A1 (de) 1979-08-16
CA1106369A (en) 1981-08-04

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