IL53635A - 4'-0-methyl derivatives of daunomycin,adriamycin and of their 4'-epi forms and process for their preparation - Google Patents

4'-0-methyl derivatives of daunomycin,adriamycin and of their 4'-epi forms and process for their preparation

Info

Publication number
IL53635A
IL53635A IL53635A IL5363577A IL53635A IL 53635 A IL53635 A IL 53635A IL 53635 A IL53635 A IL 53635A IL 5363577 A IL5363577 A IL 5363577A IL 53635 A IL53635 A IL 53635A
Authority
IL
Israel
Prior art keywords
daunomycin
adriamycin
preparation
methyl derivatives
epi forms
Prior art date
Application number
IL53635A
Other languages
English (en)
Other versions
IL53635A0 (en
Original Assignee
Farmaceutici Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia
Publication of IL53635A0 publication Critical patent/IL53635A0/xx
Publication of IL53635A publication Critical patent/IL53635A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL53635A 1976-12-22 1977-12-19 4'-0-methyl derivatives of daunomycin,adriamycin and of their 4'-epi forms and process for their preparation IL53635A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB53454/76A GB1550879A (en) 1976-12-22 1976-12-22 Antitumour glycosides

Publications (2)

Publication Number Publication Date
IL53635A0 IL53635A0 (en) 1978-03-10
IL53635A true IL53635A (en) 1981-03-31

Family

ID=10467870

Family Applications (1)

Application Number Title Priority Date Filing Date
IL53635A IL53635A (en) 1976-12-22 1977-12-19 4'-0-methyl derivatives of daunomycin,adriamycin and of their 4'-epi forms and process for their preparation

Country Status (24)

Country Link
US (1) US4183919A (ko)
JP (1) JPS5379851A (ko)
AT (1) AT354629B (ko)
AU (1) AU518244B2 (ko)
BE (1) BE862102A (ko)
CA (1) CA1090788A (ko)
CH (1) CH632770A5 (ko)
CS (1) CS198280B2 (ko)
DE (1) DE2757102C2 (ko)
DK (1) DK148098C (ko)
FI (1) FI63419C (ko)
FR (1) FR2375252A1 (ko)
GB (1) GB1550879A (ko)
GR (1) GR70040B (ko)
HU (1) HU176957B (ko)
IE (1) IE45951B1 (ko)
IL (1) IL53635A (ko)
NL (1) NL7713850A (ko)
NO (1) NO145163C (ko)
NZ (1) NZ186047A (ko)
SE (1) SE437992B (ko)
SU (1) SU797583A3 (ko)
YU (1) YU301177A (ko)
ZA (1) ZA777555B (ko)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4265885A (en) * 1978-10-25 1981-05-05 Farmitalia Carlo Erba S.P.A. Anthracyclines containing branched-chain amino-deoxy sugars
US4254110A (en) * 1979-02-02 1981-03-03 Farmitalia Carlo Erba S.P.A. Pentofuranosyl anthracyclines, intermediates in and method for their preparation and compositions and use thereof
NL8001417A (nl) * 1979-03-17 1980-09-19 Erba Farmitalia Antitumorglycosiden.
BE883759A (fr) * 1979-06-16 1980-10-01 Erba Farmitalia Glycosides d'anthracycline
ATE4387T1 (de) * 1979-07-04 1983-08-15 Farmitalia Carlo Erba S.P.A. Anthracyclin-glycoside, verfahren zu ihrer herstellung und sie enthaltende therapeutische zusammensetzung.
DE3100968A1 (de) * 1980-01-16 1982-01-14 Farmitalia Carlo Erba S.p.A., 20159 Milano Anthracyclinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
CA1248944A (en) * 1982-09-28 1989-01-17 Gareth J. Thomas Anthracycline glycosides
WO2007075094A1 (en) * 2005-12-27 2007-07-05 Instytut Biochemii I Biofizyki New derivatives of epirubicin, their medicinal application and pharmaceuticaly acceptable forms of drugs
WO2007075092A1 (en) 2005-12-29 2007-07-05 Instytut Biochemii I Biofizyki New derivatives of epirubicin, their medicinal application and pharmaceuticals acceptable forms of drugs

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1506200A (en) * 1975-04-30 1978-04-05 Farmaceutici Italia Glycosides
US3976667A (en) * 1975-06-19 1976-08-24 The Upjohn Company Steffimycinone, 7-deoxysteffimycinone and derivatives
GB1511559A (en) * 1975-09-26 1978-05-24 Farmaceutici Italia Anthracycline glycosides

Also Published As

Publication number Publication date
FI63419C (fi) 1983-06-10
FI773822A (fi) 1978-06-23
FR2375252B1 (ko) 1980-08-22
NL7713850A (nl) 1978-06-26
JPS5379851A (en) 1978-07-14
GR70040B (ko) 1982-07-26
BE862102A (fr) 1978-06-21
CH632770A5 (de) 1982-10-29
ZA777555B (en) 1978-09-27
NO145163B (no) 1981-10-19
SU797583A3 (ru) 1981-01-15
DK148098C (da) 1985-07-29
HU176957B (hu) 1981-06-28
SE7714464L (sv) 1978-06-23
YU301177A (en) 1982-06-30
DE2757102C2 (de) 1986-06-19
NO774370L (no) 1978-06-23
NZ186047A (en) 1979-06-19
GB1550879A (en) 1979-08-22
NO145163C (no) 1982-01-27
CA1090788A (en) 1980-12-02
IL53635A0 (en) 1978-03-10
FR2375252A1 (fr) 1978-07-21
DK564777A (da) 1978-06-23
FI63419B (fi) 1983-02-28
DE2757102A1 (de) 1978-07-06
IE45951B1 (en) 1983-01-12
US4183919A (en) 1980-01-15
AU3174877A (en) 1979-06-28
CS198280B2 (en) 1980-05-30
AT354629B (de) 1979-01-25
ATA907377A (de) 1979-06-15
JPS6134437B2 (ko) 1986-08-07
AU518244B2 (en) 1981-09-24
SE437992B (sv) 1985-03-25
DK148098B (da) 1985-03-04
IE45951L (en) 1978-06-22

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