ZA786963B - 5,6-dihydro-prostacyclin derivatives and process for their preparation - Google Patents

5,6-dihydro-prostacyclin derivatives and process for their preparation

Info

Publication number
ZA786963B
ZA786963B ZA00786963A ZA786963A ZA786963B ZA 786963 B ZA786963 B ZA 786963B ZA 00786963 A ZA00786963 A ZA 00786963A ZA 786963 A ZA786963 A ZA 786963A ZA 786963 B ZA786963 B ZA 786963B
Authority
ZA
South Africa
Prior art keywords
dihydro
preparation
prostacyclin derivatives
prostacyclin
derivatives
Prior art date
Application number
ZA00786963A
Inventor
A Andreoni
A Fumagalli
F Faustini
C Passarotti
R Ceserani
C Gandolfi
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of ZA786963B publication Critical patent/ZA786963B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
ZA00786963A 1977-12-30 1978-12-12 5,6-dihydro-prostacyclin derivatives and process for their preparation ZA786963B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT31423/77A IT1089247B (en) 1977-12-30 1977-12-30 5-6-DI HYDRO-PROSTACYCLINE DERIVATIVES

Publications (1)

Publication Number Publication Date
ZA786963B true ZA786963B (en) 1979-11-28

Family

ID=11233616

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00786963A ZA786963B (en) 1977-12-30 1978-12-12 5,6-dihydro-prostacyclin derivatives and process for their preparation

Country Status (10)

Country Link
JP (1) JPS54103863A (en)
BE (1) BE873129A (en)
DE (1) DE2853849A1 (en)
FR (1) FR2413383A1 (en)
GB (1) GB2012762A (en)
HU (1) HU182021B (en)
IT (1) IT1089247B (en)
NL (1) NL7812132A (en)
SE (1) SE7813428L (en)
ZA (1) ZA786963B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4126744A (en) * 1977-12-05 1978-11-21 The Upjohn Company 4-Oxo-PGI1 compounds
FR2490641A1 (en) * 1980-09-22 1982-03-26 Hoffmann La Roche 6,9-Epoxy 15-hydroxy prost-13-enoic and prostanoic acid derivs. - are antisecretories, bronchodilators, blood platelet aggregation inhibitors, antiulcer and antihypertensive cpds.
DE3035713A1 (en) * 1980-09-22 1982-04-29 F. Hoffmann-La Roche & Co. AG, 4002 Basel 6,9-Epoxy 15-hydroxy prost-13-enoic and prostanoic acid derivs. - are antisecretories, bronchodilators, blood platelet aggregation inhibitors, antiulcer and antihypertensive cpds.
EP0059307A1 (en) 1981-02-26 1982-09-08 Grünenthal GmbH Preparation of 2-oxa-bicyclo(3.3.0)octane compounds and their derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU511711B2 (en) * 1976-12-30 1980-09-04 Upjohn Company, The 6-Oxo and 5, 6-Dihalo prostaglandin analogues
US4126744A (en) * 1977-12-05 1978-11-21 The Upjohn Company 4-Oxo-PGI1 compounds

Also Published As

Publication number Publication date
JPS54103863A (en) 1979-08-15
SE7813428L (en) 1979-07-01
GB2012762A (en) 1979-08-01
FR2413383A1 (en) 1979-07-27
FR2413383B1 (en) 1982-04-09
DE2853849A1 (en) 1979-10-18
HU182021B (en) 1983-12-28
IT1089247B (en) 1985-06-18
NL7812132A (en) 1979-07-03
BE873129A (en) 1979-04-17

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