ZA786963B - 5,6-dihydro-prostacyclin derivatives and process for their preparation - Google Patents
5,6-dihydro-prostacyclin derivatives and process for their preparationInfo
- Publication number
- ZA786963B ZA786963B ZA00786963A ZA786963A ZA786963B ZA 786963 B ZA786963 B ZA 786963B ZA 00786963 A ZA00786963 A ZA 00786963A ZA 786963 A ZA786963 A ZA 786963A ZA 786963 B ZA786963 B ZA 786963B
- Authority
- ZA
- South Africa
- Prior art keywords
- dihydro
- preparation
- prostacyclin derivatives
- prostacyclin
- derivatives
- Prior art date
Links
- RJADQDXZYFCVHV-JQMWNLLFSA-N 5-[(2s,4r,5r,6ar)-5-hydroxy-4-[(e,3s)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydro-2h-cyclopenta[b]furan-2-yl]pentanoic acid Chemical class O1[C@@H](CCCCC(O)=O)CC2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@H]21 RJADQDXZYFCVHV-JQMWNLLFSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT31423/77A IT1089247B (en) | 1977-12-30 | 1977-12-30 | 5-6-DI HYDRO-PROSTACYCLINE DERIVATIVES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA786963B true ZA786963B (en) | 1979-11-28 |
Family
ID=11233616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA00786963A ZA786963B (en) | 1977-12-30 | 1978-12-12 | 5,6-dihydro-prostacyclin derivatives and process for their preparation |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS54103863A (en) |
| BE (1) | BE873129A (en) |
| DE (1) | DE2853849A1 (en) |
| FR (1) | FR2413383A1 (en) |
| GB (1) | GB2012762A (en) |
| HU (1) | HU182021B (en) |
| IT (1) | IT1089247B (en) |
| NL (1) | NL7812132A (en) |
| SE (1) | SE7813428L (en) |
| ZA (1) | ZA786963B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4126744A (en) * | 1977-12-05 | 1978-11-21 | The Upjohn Company | 4-Oxo-PGI1 compounds |
| DE3035713A1 (en) * | 1980-09-22 | 1982-04-29 | F. Hoffmann-La Roche & Co. AG, 4002 Basel | 6,9-Epoxy 15-hydroxy prost-13-enoic and prostanoic acid derivs. - are antisecretories, bronchodilators, blood platelet aggregation inhibitors, antiulcer and antihypertensive cpds. |
| FR2490641A1 (en) * | 1980-09-22 | 1982-03-26 | Hoffmann La Roche | 6,9-Epoxy 15-hydroxy prost-13-enoic and prostanoic acid derivs. - are antisecretories, bronchodilators, blood platelet aggregation inhibitors, antiulcer and antihypertensive cpds. |
| EP0059307A1 (en) | 1981-02-26 | 1982-09-08 | Grünenthal GmbH | Preparation of 2-oxa-bicyclo(3.3.0)octane compounds and their derivatives |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU511711B2 (en) * | 1976-12-30 | 1980-09-04 | Upjohn Company, The | 6-Oxo and 5, 6-Dihalo prostaglandin analogues |
| US4126744A (en) * | 1977-12-05 | 1978-11-21 | The Upjohn Company | 4-Oxo-PGI1 compounds |
-
1977
- 1977-12-30 IT IT31423/77A patent/IT1089247B/en active
-
1978
- 1978-12-12 ZA ZA00786963A patent/ZA786963B/en unknown
- 1978-12-13 NL NL7812132A patent/NL7812132A/en not_active Application Discontinuation
- 1978-12-13 DE DE19782853849 patent/DE2853849A1/en not_active Withdrawn
- 1978-12-14 GB GB7848599A patent/GB2012762A/en not_active Withdrawn
- 1978-12-28 BE BE192605A patent/BE873129A/en not_active IP Right Cessation
- 1978-12-28 JP JP16597878A patent/JPS54103863A/en active Pending
- 1978-12-29 FR FR7836902A patent/FR2413383A1/en active Granted
- 1978-12-29 SE SE7813428A patent/SE7813428L/en unknown
- 1978-12-29 HU HU78EA188A patent/HU182021B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SE7813428L (en) | 1979-07-01 |
| NL7812132A (en) | 1979-07-03 |
| JPS54103863A (en) | 1979-08-15 |
| BE873129A (en) | 1979-04-17 |
| GB2012762A (en) | 1979-08-01 |
| DE2853849A1 (en) | 1979-10-18 |
| FR2413383A1 (en) | 1979-07-27 |
| HU182021B (en) | 1983-12-28 |
| IT1089247B (en) | 1985-06-18 |
| FR2413383B1 (en) | 1982-04-09 |
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