IL51222A - Etherified hydroxy-benzodiheterocyclic compounds,their prearation and pharmaceutical compositions containing them - Google Patents

Etherified hydroxy-benzodiheterocyclic compounds,their prearation and pharmaceutical compositions containing them

Info

Publication number
IL51222A
IL51222A IL51222A IL5122277A IL51222A IL 51222 A IL51222 A IL 51222A IL 51222 A IL51222 A IL 51222A IL 5122277 A IL5122277 A IL 5122277A IL 51222 A IL51222 A IL 51222A
Authority
IL
Israel
Prior art keywords
benzodiheterocyclic
prearation
compounds
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL51222A
Other languages
English (en)
Other versions
IL51222A0 (en
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of IL51222A0 publication Critical patent/IL51222A0/xx
Publication of IL51222A publication Critical patent/IL51222A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/78Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/80Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40Benzopyrazines
    • C07D241/44Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/041,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/121,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/141,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/181,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/341,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/361,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/101,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/24Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IL51222A 1976-01-08 1977-01-06 Etherified hydroxy-benzodiheterocyclic compounds,their prearation and pharmaceutical compositions containing them IL51222A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH16176A CH624395A5 (fr) 1976-01-08 1976-01-08

Publications (2)

Publication Number Publication Date
IL51222A0 IL51222A0 (en) 1977-03-31
IL51222A true IL51222A (en) 1980-12-31

Family

ID=4180641

Family Applications (1)

Application Number Title Priority Date Filing Date
IL51222A IL51222A (en) 1976-01-08 1977-01-06 Etherified hydroxy-benzodiheterocyclic compounds,their prearation and pharmaceutical compositions containing them

Country Status (26)

Country Link
US (2) US4140789A (fr)
JP (1) JPS5285166A (fr)
AR (4) AR214869A1 (fr)
AT (1) AT355564B (fr)
AU (1) AU507884B2 (fr)
BE (1) BE850166A (fr)
CA (1) CA1083150A (fr)
CH (1) CH624395A5 (fr)
CS (1) CS201040B2 (fr)
DD (1) DD129444A5 (fr)
DE (1) DE2700193A1 (fr)
DK (1) DK6177A (fr)
ES (1) ES454779A1 (fr)
FI (1) FI770036A (fr)
FR (1) FR2337718A1 (fr)
GB (1) GB1549945A (fr)
GR (1) GR73132B (fr)
IE (1) IE44246B1 (fr)
IL (1) IL51222A (fr)
NL (1) NL7700141A (fr)
NO (1) NO770061L (fr)
NZ (1) NZ182963A (fr)
PL (4) PL112491B1 (fr)
SE (1) SE7700056L (fr)
SU (4) SU648091A3 (fr)
ZA (1) ZA7787B (fr)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH624395A5 (fr) * 1976-01-08 1981-07-31 Ciba Geigy Ag
DE2644833A1 (de) * 1976-10-05 1978-04-20 Boehringer Sohn Ingelheim Neue 1-aryloxy-2-hydroxy-3-alkylenaminopropane und verfahren zu ihrer herstellung
NZ187066A (en) * 1977-05-03 1981-02-11 Hoffmann La Roche 4-(3-substitutedamino-2-hydroxypropoxy)-benzimidazolidin-2-(ones or thiones)
CA1108619A (fr) * 1977-08-12 1981-09-08 Carl H. Ross Derives de 4-hydroxy-2-benzimidazolinone et leur preparation
DE2801980A1 (de) * 1978-01-18 1979-07-19 Boehringer Mannheim Gmbh 4-hydroxy-2-benzimidazolin-thion- derivate, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
EP0003758A1 (fr) * 1978-02-09 1979-09-05 Ciba-Geigy Ag Hydroxy-benzodihétérocycles éthérifiés et leurs sels d'addition acides, procédé pour leur préparation et compositions pharmaceutiques les contenant
DE2905877A1 (de) 1979-02-16 1980-08-28 Boehringer Mannheim Gmbh Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DD150456A5 (de) * 1979-03-01 1981-09-02 Ciba Geigy Ag Verfahren zur herstellung von derivaten des 3-amino-1,2-propandiols
BE883069A (fr) 1979-05-04 1980-08-18 Continental Pharma Derives de phenylethylamine, leur preparation et utilisation ainsi que composition contenant ces derives.
DE2922084A1 (de) 1979-05-31 1980-12-11 Boehringer Mannheim Gmbh Neue aminopropanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4656168A (en) * 1980-12-23 1987-04-07 Merck & Co., Inc. (3-aralkylamino-2-or-propoxy)heterocyclic compounds in method of effecting bronchodilation
US4349673A (en) * 1980-12-23 1982-09-14 Merck & Co., Inc. Benzoxazines
US4331679A (en) * 1980-12-23 1982-05-25 Merck Sharp & Dohme (I.A.) Corp. (3-Aralkylamino-2-or-propoxy) heterocyclic compounds
US4442094A (en) * 1980-12-23 1984-04-10 Merck & Co., Inc. (3-Aralkylamino-2-or-propoxy)heterocyclic compounds
DE3217012A1 (de) * 1982-05-06 1983-11-10 Dr. Karl Thomae Gmbh, 7950 Biberach Benzoxazin-2-one, deren herstellung und diese verbindungen enthaltende arzneimittel
IT1212552B (it) * 1982-10-20 1989-11-30 Italo Britannica L Manet Ti H Alcanolaminossi derivati di 3,4-diidro-2h-1.4-benzotiazin-3-one, loro procedimento di produzione e loro utilizzazione farmaceutica
GB8419797D0 (en) * 1984-08-03 1984-09-05 Beecham Group Plc Compounds
DE3800096A1 (de) * 1988-01-05 1989-07-13 Bayer Ag Verwendung von benzimidazolderivaten als leistungsfoerderer
FR2653430B1 (fr) * 1989-10-23 1991-12-20 Pf Medicament Nouveaux derives de dihydro-1,2 oxo-2 quinoxalines, leur preparation et leur application en therapeutique.
ZA967892B (en) * 1995-09-21 1998-03-18 Lilly Co Eli Selective β3 adrenergic agonists.
EP0827746B1 (fr) 1996-09-05 2002-04-03 Eli Lilly And Company Analogues de carbazole étant agonistes beta3-adrénergiques sélectifs
US5808080A (en) 1996-09-05 1998-09-15 Eli Lilly And Company Selective β3 adrenergic agonists
US5922715A (en) * 1997-02-18 1999-07-13 American Home Products Corporation 5-aminoalkoxy-1, 4-dihydroquinoxaline-2, 3-diones
US5990144A (en) * 1997-02-18 1999-11-23 American Home Products Corporation 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one dopamine autoreceptor agonists
US5972958A (en) * 1997-02-18 1999-10-26 American Home Products Corporation 4-aminoalkoxy-1,3-dihydro-benzoimidazol-2-thiones
EP0905121B1 (fr) * 1997-09-24 2002-07-03 Infineon Technologies AG Composés o-nitro(thio)phénoliques et leur préparation
CO5011072A1 (es) * 1997-12-05 2001-02-28 Lilly Co Eli Etanolaminas pirazinil substituidas como agfonistas de los receptores
WO2001036412A1 (fr) * 1999-11-15 2001-05-25 Eli Lilly And Company Procede de preparation d'aryloxypropanolamines
FR2805159B1 (fr) 2000-02-23 2005-06-10 Oreal Compositions pour la teinture d'oxydation des fibres keratiniques comprenant un n-(2-hydroxybenzene)-carbamate ou un n-(2-hydroxybenzene)-uree a titre de coupleur, et procedes de teinture
US6825220B2 (en) 2000-11-10 2004-11-30 Eli Lilly And Company 3-Substituted oxindole β 3 agonists
WO2003016307A1 (fr) 2001-08-14 2003-02-27 Eli Lilly And Company Agonistes de beta-3 adrenergiques
DE60211199T2 (de) 2001-08-14 2007-02-01 Eli Lilly And Co., Indianapolis 3-substituierte oxindol-beta-3-agonisten
JP2005514366A (ja) 2001-11-20 2005-05-19 イーライ・リリー・アンド・カンパニー 3−置換オキシインドールβ3アゴニスト
JP2005518357A (ja) 2001-11-20 2005-06-23 イーライ・リリー・アンド・カンパニー ベータ3アドレナリンアゴニスト
EP1467733A1 (fr) 2002-01-11 2004-10-20 Eli Lilly And Company Derives d'ethanolamine a substitution de 2-oxo-benzimidazolyle, et leur utilisation comme beta3 agonistes
JP4569755B2 (ja) 2002-08-29 2010-10-27 日産化学工業株式会社 アミノベンゾピラン化合物の製造方法
AU2004259703A1 (en) * 2003-07-15 2005-02-03 Smithkline Beecham Corporation Novel compounds
EP2079739A2 (fr) * 2006-10-04 2009-07-22 Pfizer Products Inc. Dérivés de pyrido[4,3-d]pyrimidin-4(3h)-one utilisés en tant qu'antagonistes du récepteur calcique
WO2014108449A1 (fr) 2013-01-08 2014-07-17 Atrogi Ab Procédé de criblage, trousse, méthode de traitement et composé destinés à être utilisé dans une méthode de traitement
GB201714736D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714745D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714734D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714740D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB202205895D0 (en) 2022-04-22 2022-06-08 Atrogi Ab New medical uses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA726737A (en) * 1966-01-25 C. Scarborough Homer 4-substituted quinolines and quinazolines
US3686176A (en) * 1970-03-09 1972-08-22 Frosst & Co Charles E 1-morpholino phenoxy-3-alkylamino-2-propanols
US3763153A (en) * 1972-02-22 1973-10-02 Squibb & Sons Inc Benzothiazines
GB1488330A (en) * 1973-12-19 1977-10-12 Smith Kline French Lab Dihydropyridazinones
CH624395A5 (fr) * 1976-01-08 1981-07-31 Ciba Geigy Ag

Also Published As

Publication number Publication date
GR73132B (fr) 1984-02-07
AR217258A1 (es) 1980-03-14
DD129444A5 (de) 1978-01-18
CH624395A5 (fr) 1981-07-31
CA1083150A (fr) 1980-08-05
AT355564B (de) 1980-03-10
FR2337718A1 (fr) 1977-08-05
CS201040B2 (en) 1980-10-31
NZ182963A (en) 1978-07-28
IL51222A0 (en) 1977-03-31
AU2110577A (en) 1978-07-13
AU507884B2 (en) 1980-02-28
ATA4677A (de) 1979-08-15
SU648091A3 (ru) 1979-02-15
BE850166A (fr) 1977-07-07
DE2700193A1 (de) 1977-07-14
PL195154A1 (pl) 1979-05-07
JPS5285166A (en) 1977-07-15
FI770036A (fr) 1977-07-09
AR214869A1 (es) 1979-08-15
ES454779A1 (es) 1978-01-01
ZA7787B (en) 1977-11-30
DK6177A (da) 1977-07-09
PL110654B1 (en) 1980-07-31
SE7700056L (sv) 1977-07-09
AR214746A1 (es) 1979-07-31
IE44246L (en) 1977-07-08
US4310527A (en) 1982-01-12
NL7700141A (nl) 1977-07-12
FR2337718B1 (fr) 1980-11-07
SU645568A3 (ru) 1979-01-30
SU651695A3 (ru) 1979-03-05
IE44246B1 (en) 1981-09-23
US4140789A (en) 1979-02-20
PL112442B1 (en) 1980-10-31
SU648092A3 (ru) 1979-02-15
GB1549945A (en) 1979-08-08
AR215643A1 (es) 1979-10-31
PL112491B1 (en) 1980-10-31
NO770061L (no) 1977-07-11
PL112441B1 (en) 1980-10-31

Similar Documents

Publication Publication Date Title
IL51222A (en) Etherified hydroxy-benzodiheterocyclic compounds,their prearation and pharmaceutical compositions containing them
IL52131A (en) Substituted 4-amino-4-arylcyclohexanones and their ketals,their preparation and pharmaceutical compositions containing them
JPS52143218A (en) Pharmaceutical composition
HK12884A (en) N-aminoalkyl-heterocycles,methods for their preparation and compositions containing them
JPS52113976A (en) Pharmaceutical composition
JPS5362838A (en) Pharmaceutical composition
JPS52102432A (en) Pharmaceutical composition containing pyretrinoid
IL53043A (en) N-heterocyclylalkyl-(1-aryloxy-2-hydroxy-3-amino-propane)derivatives,their preparation and pharmaceutical compositions containing them
JPS5372814A (en) Pharmaceutical composition
IL49325A (en) 8-aza-11-deoxy-pge1 derivatives,their preparation and pharmaceutical compositions containing them
IL51309A0 (en) New 1,2-benzisothiazolin-3-ones,their preparation and pharmaceutical compositions containing them
IL52433A (en) 2-bromo-6-fluoro-n-2-imidazolidinylidene-benzamine and pharmaceutical compositions containing them
AU3152677A (en) Pharmaceutical composition
IL52717A (en) Derivatives of2-phenylamino-imidazoline-(2),their preparation and pharmaceutical compositions containing them
IL52857A (en) Oxo-benzopyrane derivatives,their preparation and pharmaceutical compositions containing them
IL52137A (en) N-heterocyclic-n-(hetero)arylfluoroalkylamines,their preparation and pharmaceutical compositions containing them
IL52615A (en) 1-aza-prostaglandin analogues,their preparation and pharmaceutical compositions containing them
JPS5356634A (en) Pharmaceutical composition
AU2649977A (en) Pharmaceutical composition
IL55018A (en) Benzylpyrimidines,their manufacture and pharmaceutical compositions containing them
IL51468A (en) 17 -hydroxy- -d-homosteroid derivatives,their preparation and pharmaceutical compositions containing them
IL51373A (en) Pharmaceutical compositions containing halocinnamides,certain such compounds and their preparation
PH13885A (en) New perhydroindolinols and pharmaceutical compositions containing them
IL56529A0 (en) Azathianaphthalene derivatives, their manufacture and pharmaceutical compositions containing them
JPS5283918A (en) Pharmaceutical composition