IL50774A - Preparation of D -) - () p - hydroxyphenyl (- glycyl chloride hydrochloride - Google Patents

Preparation of D -) - () p - hydroxyphenyl (- glycyl chloride hydrochloride

Info

Publication number
IL50774A
IL50774A IL50774A IL5077473A IL50774A IL 50774 A IL50774 A IL 50774A IL 50774 A IL50774 A IL 50774A IL 5077473 A IL5077473 A IL 5077473A IL 50774 A IL50774 A IL 50774A
Authority
IL
Israel
Prior art keywords
hydroxyphenyl
reaction
prepared
phosgene
chloride
Prior art date
Application number
IL50774A
Other languages
English (en)
Hebrew (he)
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IL50774A publication Critical patent/IL50774A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL50774A 1972-12-26 1973-12-25 Preparation of D -) - () p - hydroxyphenyl (- glycyl chloride hydrochloride IL50774A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31834072A 1972-12-26 1972-12-26

Publications (1)

Publication Number Publication Date
IL50774A true IL50774A (en) 1977-08-31

Family

ID=23237764

Family Applications (3)

Application Number Title Priority Date Filing Date
IL50774A IL50774A (en) 1972-12-26 1973-12-25 Preparation of D -) - () p - hydroxyphenyl (- glycyl chloride hydrochloride
IL43913A IL43913A (en) 1972-12-26 1973-12-25 Preparation of acid D] - 7) a - amino - a - p - hydroxyphenyl (- acetamido [- 3 -) 1, 2, 3 - triazole - 5 - ile (thymethyl - 3 - cephalic - 4 - carboxylitol salt
IL50774A IL50774A0 (en) 1972-12-26 1976-10-27 The preparation of d-(-)-2-(p-hydroxyphenyl)-glycyl chloride hydrochloride

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL43913A IL43913A (en) 1972-12-26 1973-12-25 Preparation of acid D] - 7) a - amino - a - p - hydroxyphenyl (- acetamido [- 3 -) 1, 2, 3 - triazole - 5 - ile (thymethyl - 3 - cephalic - 4 - carboxylitol salt
IL50774A IL50774A0 (en) 1972-12-26 1976-10-27 The preparation of d-(-)-2-(p-hydroxyphenyl)-glycyl chloride hydrochloride

Country Status (23)

Country Link
JP (4) JPS5652024B2 (hu)
KR (1) KR780000197B1 (hu)
AR (4) AR203636A1 (hu)
AT (1) AT331397B (hu)
BE (1) BE808924A (hu)
BG (3) BG21234A3 (hu)
CH (1) CH602760A5 (hu)
DD (2) DD110664A5 (hu)
DE (1) DE2364192A1 (hu)
ES (3) ES421707A1 (hu)
FR (2) FR2211216B1 (hu)
GB (3) GB1460915A (hu)
HU (2) HU169451B (hu)
IL (3) IL50774A (hu)
IN (1) IN139259B (hu)
LU (1) LU69080A1 (hu)
NL (1) NL7317715A (hu)
NO (1) NO142710C (hu)
OA (1) OA04655A (hu)
RO (1) RO66051A (hu)
SE (2) SE7512971L (hu)
SU (1) SU576948A3 (hu)
ZA (1) ZA739607B (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3907667A (en) * 1973-08-22 1975-09-23 Gulf Research Development Co Process for producing a lubricating oil from a residue feed
NZ179268A (en) * 1974-12-13 1978-04-28 Bristol Myers Co Derivative of cephalosporin c, the preparation of certain cephalosporins
NL162387C (nl) * 1977-09-06 1980-05-16 Gist Brocades Nv Werkwijze voor het bereiden van 6-(d-alpha-amino-p- -hydroxyfenylacetamido)penicillanzuur.
EP0018546B1 (en) * 1979-04-25 1983-09-28 BIOCHEMIE Gesellschaft m.b.H. Process for the production of phenylglycyl chloride hydrochlorides
ATA308979A (de) * 1979-04-25 1982-01-15 Biochemie Gmbh Verfahren zur herstellung von (d)-phenylglycylchlorid hydrochloryd-derivaten
JPS6128429A (ja) * 1983-10-21 1986-02-08 Kazuo Ogata 均質機の分割式均質装置
IT1186778B (it) * 1985-10-15 1987-12-16 Lark Spa Cefatrizina glicerolo solvato cristallino e procedimento per la sua preparazione
JPH01152718U (hu) * 1988-04-13 1989-10-20
CN103772414B (zh) * 2013-12-31 2016-03-09 福建省福抗药业股份有限公司 一种制备丙二醇头孢曲嗪的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1159449B (de) * 1961-03-22 1963-12-19 Gruenenthal Chemie Verfahren zur Herstellung von 6-Acylaminopenicillansaeuren und deren Salzen
IL38099A (en) * 1970-12-17 1976-01-30 Smith Kline French Lab 3-heterocyclyl thiomethylcephalosporins
IE36346B1 (en) * 1971-05-11 1976-10-13 R & L Molecular Research Ltd Antibacterial agents and a process for the preparation thereof
CA1076560A (en) * 1972-06-14 1980-04-29 Smith Kline And French Canada Ltd. 3-heterocyclic thiomethylcephalosporins

Also Published As

Publication number Publication date
FR2211216B1 (hu) 1977-04-22
FR2267307B1 (hu) 1978-05-19
FR2211216A1 (hu) 1974-07-19
BG21234A3 (bg) 1976-03-20
AR205561A1 (es) 1976-05-14
ES444926A1 (es) 1977-11-16
HU169451B (hu) 1976-11-28
IL43913A0 (en) 1974-03-14
HU167560B (hu) 1975-11-28
NL7317715A (hu) 1974-06-28
NO743649L (no) 1974-06-27
JPS5912661B2 (ja) 1984-03-24
DE2364192A1 (de) 1974-06-27
JPS5191283A (en) 1976-08-10
CH602760A5 (hu) 1978-07-31
JPS5652024B2 (hu) 1981-12-09
ATA1083073A (de) 1975-11-15
JPS5953277B2 (ja) 1984-12-24
RO66051A (fr) 1979-08-15
DD110664A5 (hu) 1975-01-05
FR2267307A1 (hu) 1975-11-07
BG21233A3 (bg) 1976-03-20
BE808924A (fr) 1974-06-20
IL50774A0 (en) 1976-12-31
ES421707A1 (es) 1976-09-16
ZA739607B (en) 1974-09-25
SE404692B (sv) 1978-10-23
NO142710C (no) 1980-10-01
JPS5191282A (en) 1976-08-10
LU69080A1 (hu) 1974-08-19
SE7512972L (sv) 1975-11-18
OA04655A (fr) 1980-12-31
AT331397B (de) 1976-08-25
GB1460914A (en) 1977-01-06
ES444927A1 (es) 1977-04-16
NO142710B (no) 1980-06-23
SE7512971L (sv) 1975-11-18
JPS4994696A (hu) 1974-09-09
IL43913A (en) 1977-08-31
KR780000197B1 (en) 1978-05-26
BG21601A3 (bg) 1976-07-20
IN139259B (hu) 1976-05-29
AR203896A1 (es) 1975-10-31
AR203636A1 (es) 1975-09-30
AU6384773A (en) 1975-06-26
GB1460916A (en) 1977-01-06
GB1460915A (en) 1977-01-06
AR205560A1 (es) 1976-05-14
SU576948A3 (ru) 1977-10-15
DD116602A5 (hu) 1975-12-05
JPS5191224A (en) 1976-08-10

Similar Documents

Publication Publication Date Title
EP0019345B1 (en) Process for the preparation of a (d-alpha-amino-(p-hydroxyphenyl)-acetamido) group containing cephalosporanic acid derivatives
JPH0313237B2 (hu)
CN106749242B (zh) 阿维巴坦中间体的制备方法
WO2005121154A1 (en) Process for the preparation of cefdinir
IL50774A (en) Preparation of D -) - () p - hydroxyphenyl (- glycyl chloride hydrochloride
US4258195A (en) Novel thiol esters and process for preparing cephalosporin compounds using same
US3518260A (en) Method for preparing aminoacyl cephalosporins
KR100789156B1 (ko) 세팔로스포린 중간체
EP0262744B1 (en) A process for preparing 3-alkoxymethylcephalosphorins
EP0175814B1 (en) Process for preparing cephem derivatives
KR100249581B1 (ko) 7-알파-아미노아실-세팔로스포린의 제조방법
EP0844999B1 (en) Purification process
KR830001905B1 (ko) 소디움 세펄옥심의 제조방법
CA1052769A (en) Process for preparing cefazolin
JPS6133833B2 (hu)
US4247461A (en) Esterification process using methoxymethyl-P-toluenesulfonate
US4584371A (en) Catalytic process for preparing 3-ester-methyl cephalosporins from desacetyl-7-aminocephalosporanic acid
EP0004570A1 (en) Thiol esters, process for their preparation, pharmaceutical compositions containing them and a process for preparing cephalosporin compounds using the same
BG61163B1 (bg) Метод за получаване на цефалоспоринов антибиотикпри използване на син-изомер на тиазолилов междинен продукт
JPS5858341B2 (ja) カガクテキホウホウ
US4351947A (en) Tetrazole derivative
KR800001419B1 (ko) 염화 2-(p-하이드록시페닐) 글라이실·염산염의 제조방법
DK156221B (da) Fremgangsmaade til fremstilling af penicillansyre- og cephalosporansyrederivater
SU503525A3 (ru) Способ получени 3-карбамоилоксиметилцефалоспоринов
US4082766A (en) Process for preparing n-chlorophthalimide